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The map label for this gene is clpB [H]

Identifier: 188584788

GI number: 188584788

Start: 169117

End: 171561

Strand: Direct

Name: clpB [H]

Synonym: Nther_0146

Alternate gene names: 188584788

Gene position: 169117-171561 (Clockwise)

Preceding gene: 188584787

Following gene: 188584789

Centisome position: 5.34

GC content: 39.59

Gene sequence:

>2445_bases
ATGTTTGCTAGATTTACTCAAAGAGCCCAAAAAGTCATGGCTCTATCACAAGATGAGGCGAAAAGACTAAATCATAATTA
TATAGGCACTGAACATTTACTACTGGGTCTTATTAGAGAAGGTGAAGGAATTGCTGCCCAGACCTTCAAGAACTTAGGAG
TTGATTTGGAAGAAGTTAGAGAAGCTGTGGAGAATTTAGTACAACCGGGTGAAGAACAAGTTAGTGGAAATGTGGGCTAT
ACACCCAGGGTCAAAACAGTAATTGAACTATCTATGGAAGAGGCACGGCGAATGGGTCACAACTATATAGGAACCGAGCA
CTTATTGTTGGGATTAGTTAAAGAAGGAGAAGGTATAGCCGCTAAGGTACTTCAAGAATTAGGTGTTGACTTAGATAAAG
CCCGGGAAGAAGTGCTAAAAATAATTGGTGGTAGTCAGCAGCCAAAAGGTCAAGCCAATTTTGGTCAGGCTCAAAATCCC
AAAATGGCAAATAGAGACAAAACACCTACTTTAGATAATTTTGGAAGAGACCTGACTAAACTAGCTGAAGAAGGCAAACT
AGATCCGGTGATTGGACGTAAAAAGGAAATTGAACGGGTTATCCAGGTATTAAGCAGAAGGACAAAGAATAATCCTTGTT
TAATAGGTGAACCAGGAGTAGGTAAAACTGCTATTGCTGAAGGTTTAGCCCAAAAGATAATTGAAGGTGAGGTACCCAAG
ATACTCGAAAACAAACGAGTTGTCACTCTTGAATTGTCTGCAGTGGTTGCAGGAACAAAATATAGAGGTGAGTTTGAGGA
AAGATTACGTAAATTGATTGATGAATTAACTGATAGTGGTGAAGTTATTATCTTCATTGACGAAATCCACACTATGATTG
GCGCAGGTGCCGCTGAGGGAGCTATCGATGCTTCAAATATTCTCAAACCAGCTCTAGCAAAAGGGGAACTACAATGCATA
GGTGCAACTACCCTTGATGAATATCGAAAATATATTGAAAAAGATTCGGCCCTAGAGCGTCGTTTCCAGCCAGTTACCGT
TGATGAACCTAGTAAAGAAGCAACTGTTGAAATACTTAAAGGTTTAAGAGATCGTTATGAAGCTCATCATAGAGTTCAAA
TAACAGATGACGCCATTGAAGCTAGTGTGAAAATGTCAGACAGGTATATTACTGATAGATATTTACCTGACAAAGCTATA
GATTTAATTGATGAAGCTGCTTCTAATGTTAAACTTAAAACTAATACTGCACCGCCAGATATGAGGAAACTGGAAGAAGA
TCTTGAGGAAATAGAAAAAGAAAAAGAAGCTGCAGTTAAAAGTCAAGATTTTGAACAGGCAGCCAAATTAAGGGATAAAG
AACAAGAAATTAAAAAAGAGTTAGAAGATATGGAAAAAAGCTGGGAGAAAAAACAGTTGTCCGACGAAGCTCAAGTAACT
GAGGAGGATATAGCTAGAATTGTGTCGGATTGGACTGGAATACCTGTAAAGCGCTTGGCCCAGGAAGAAACCGAACGTCT
GTTGAATATGGAAGACGCTCTCCACCAACGAGTTGTAGGTCAAGAAGAGGCGGTCCAGTCGGTATCAAATGCTATTAGAA
GAGCACGCTCTGGTCTAAAAGATCCCAAAAGACCTATTGGCTCTTTTATATTCCTTGGGCCTACAGGGGTAGGAAAAACT
GAACTTGCCAGAGCTCTGGCTGATGTGTTATTTGGCGATGAAGATGCTATGATTAGATTAGATATGTCAGAGTATATGGA
AAAGCACACGGTTTCGAGACTACTAGGGTCACCACCGGGATACGTAGGCCACGAAGAATCTGGACAGCTAACGGAAAAAG
TTCGTCGCCGCCCTTATTCGGTTATTCTACTTGATGAGATAGAAAAGGCCCATCCAGAAGTCTTTAATACATTGTTGCAA
GTTCTAGAAGATGGTCGCTTAACTGACGCTAAAGGTAGAACTGTAGATTTTAGAAATACTGTTATAATTATGACCTCCAA
TGTAGGAGCAAACTTAATTAGAAATGAAAGCAAGGTAGGTTTCAAACCTCAAACCAGTGAAGATTCATATAAAGAAATGA
AAGATAATGTTATGAGTGAACTTAAGAACTCATTCCGACCAGAGTTTTTAAATCGAGTAGATGAAGTAATCGTTTTCCAT
GCACTTGAAAAAGAACATTTATCTGACATTGTGGAACTAATGCTAGAAGAATTGAAGGAAAGAATGGCCGAATTTAACAT
GAACTTAGAGTTTACGGAAGAGTCTAAAAAACATTTGGCAGAGCAGGGCTATGACCCTACCTACGGAGCCCGTCCTTTAC
GCCGTGTAATTCAAAAGCAAGTAGAAGATGTCTTATCTGAGAAAATGCTAAGCGGCGAGTTTGCCCACGGTGAAACAGTT
GTTATCGATGCCGAAGACAATGAACTAAGCTTTAAAAAGAAGTAA

Upstream 100 bases:

>100_bases
TGAGAGGGATACCAAACGAGCGGAAATTATACAGAAAAGAATAAATATGAATACAGATAAACAAGAATAAGGAAATTACT
ATTTAAAGCGGGGTGATAGT

Downstream 100 bases:

>100_bases
CTAATGAAATATTAATAAAAAACGGGGCAAATGCCCCGTTTTTTATTATTTTATTTTTATTGACTATTTGAAGGAATAGT
ATTAGTTTTTGTCGAATCAT

Product: ATPase AAA-2 domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 814; Mature: 814

Protein sequence:

>814_residues
MFARFTQRAQKVMALSQDEAKRLNHNYIGTEHLLLGLIREGEGIAAQTFKNLGVDLEEVREAVENLVQPGEEQVSGNVGY
TPRVKTVIELSMEEARRMGHNYIGTEHLLLGLVKEGEGIAAKVLQELGVDLDKAREEVLKIIGGSQQPKGQANFGQAQNP
KMANRDKTPTLDNFGRDLTKLAEEGKLDPVIGRKKEIERVIQVLSRRTKNNPCLIGEPGVGKTAIAEGLAQKIIEGEVPK
ILENKRVVTLELSAVVAGTKYRGEFEERLRKLIDELTDSGEVIIFIDEIHTMIGAGAAEGAIDASNILKPALAKGELQCI
GATTLDEYRKYIEKDSALERRFQPVTVDEPSKEATVEILKGLRDRYEAHHRVQITDDAIEASVKMSDRYITDRYLPDKAI
DLIDEAASNVKLKTNTAPPDMRKLEEDLEEIEKEKEAAVKSQDFEQAAKLRDKEQEIKKELEDMEKSWEKKQLSDEAQVT
EEDIARIVSDWTGIPVKRLAQEETERLLNMEDALHQRVVGQEEAVQSVSNAIRRARSGLKDPKRPIGSFIFLGPTGVGKT
ELARALADVLFGDEDAMIRLDMSEYMEKHTVSRLLGSPPGYVGHEESGQLTEKVRRRPYSVILLDEIEKAHPEVFNTLLQ
VLEDGRLTDAKGRTVDFRNTVIIMTSNVGANLIRNESKVGFKPQTSEDSYKEMKDNVMSELKNSFRPEFLNRVDEVIVFH
ALEKEHLSDIVELMLEELKERMAEFNMNLEFTEESKKHLAEQGYDPTYGARPLRRVIQKQVEDVLSEKMLSGEFAHGETV
VIDAEDNELSFKKK

Sequences:

>Translated_814_residues
MFARFTQRAQKVMALSQDEAKRLNHNYIGTEHLLLGLIREGEGIAAQTFKNLGVDLEEVREAVENLVQPGEEQVSGNVGY
TPRVKTVIELSMEEARRMGHNYIGTEHLLLGLVKEGEGIAAKVLQELGVDLDKAREEVLKIIGGSQQPKGQANFGQAQNP
KMANRDKTPTLDNFGRDLTKLAEEGKLDPVIGRKKEIERVIQVLSRRTKNNPCLIGEPGVGKTAIAEGLAQKIIEGEVPK
ILENKRVVTLELSAVVAGTKYRGEFEERLRKLIDELTDSGEVIIFIDEIHTMIGAGAAEGAIDASNILKPALAKGELQCI
GATTLDEYRKYIEKDSALERRFQPVTVDEPSKEATVEILKGLRDRYEAHHRVQITDDAIEASVKMSDRYITDRYLPDKAI
DLIDEAASNVKLKTNTAPPDMRKLEEDLEEIEKEKEAAVKSQDFEQAAKLRDKEQEIKKELEDMEKSWEKKQLSDEAQVT
EEDIARIVSDWTGIPVKRLAQEETERLLNMEDALHQRVVGQEEAVQSVSNAIRRARSGLKDPKRPIGSFIFLGPTGVGKT
ELARALADVLFGDEDAMIRLDMSEYMEKHTVSRLLGSPPGYVGHEESGQLTEKVRRRPYSVILLDEIEKAHPEVFNTLLQ
VLEDGRLTDAKGRTVDFRNTVIIMTSNVGANLIRNESKVGFKPQTSEDSYKEMKDNVMSELKNSFRPEFLNRVDEVIVFH
ALEKEHLSDIVELMLEELKERMAEFNMNLEFTEESKKHLAEQGYDPTYGARPLRRVIQKQVEDVLSEKMLSGEFAHGETV
VIDAEDNELSFKKK
>Mature_814_residues
MFARFTQRAQKVMALSQDEAKRLNHNYIGTEHLLLGLIREGEGIAAQTFKNLGVDLEEVREAVENLVQPGEEQVSGNVGY
TPRVKTVIELSMEEARRMGHNYIGTEHLLLGLVKEGEGIAAKVLQELGVDLDKAREEVLKIIGGSQQPKGQANFGQAQNP
KMANRDKTPTLDNFGRDLTKLAEEGKLDPVIGRKKEIERVIQVLSRRTKNNPCLIGEPGVGKTAIAEGLAQKIIEGEVPK
ILENKRVVTLELSAVVAGTKYRGEFEERLRKLIDELTDSGEVIIFIDEIHTMIGAGAAEGAIDASNILKPALAKGELQCI
GATTLDEYRKYIEKDSALERRFQPVTVDEPSKEATVEILKGLRDRYEAHHRVQITDDAIEASVKMSDRYITDRYLPDKAI
DLIDEAASNVKLKTNTAPPDMRKLEEDLEEIEKEKEAAVKSQDFEQAAKLRDKEQEIKKELEDMEKSWEKKQLSDEAQVT
EEDIARIVSDWTGIPVKRLAQEETERLLNMEDALHQRVVGQEEAVQSVSNAIRRARSGLKDPKRPIGSFIFLGPTGVGKT
ELARALADVLFGDEDAMIRLDMSEYMEKHTVSRLLGSPPGYVGHEESGQLTEKVRRRPYSVILLDEIEKAHPEVFNTLLQ
VLEDGRLTDAKGRTVDFRNTVIIMTSNVGANLIRNESKVGFKPQTSEDSYKEMKDNVMSELKNSFRPEFLNRVDEVIVFH
ALEKEHLSDIVELMLEELKERMAEFNMNLEFTEESKKHLAEQGYDPTYGARPLRRVIQKQVEDVLSEKMLSGEFAHGETV
VIDAEDNELSFKKK

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=324, Percent_Identity=37.6543209876543, Blast_Score=202, Evalue=1e-51,
Organism=Escherichia coli, GI1788943, Length=872, Percent_Identity=47.3623853211009, Blast_Score=770, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=811, Percent_Identity=38.5943279901356, Blast_Score=540, Evalue=1e-154,
Organism=Saccharomyces cerevisiae, GI6320464, Length=704, Percent_Identity=47.4431818181818, Blast_Score=656, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=877, Percent_Identity=37.2862029646522, Blast_Score=560, Evalue=1e-160,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150
- InterPro:   IPR001943 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 91628; Mature: 91628

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS50151 UVR ; PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFARFTQRAQKVMALSQDEAKRLNHNYIGTEHLLLGLIREGEGIAAQTFKNLGVDLEEVR
CCCHHHHHHHHHHHHCHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHH
EAVENLVQPGEEQVSGNVGYTPRVKTVIELSMEEARRMGHNYIGTEHLLLGLVKEGEGIA
HHHHHHHCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHH
AKVLQELGVDLDKAREEVLKIIGGSQQPKGQANFGQAQNPKMANRDKTPTLDNFGRDLTK
HHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
LAEEGKLDPVIGRKKEIERVIQVLSRRTKNNPCLIGEPGVGKTAIAEGLAQKIIEGEVPK
HHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHCCCCHH
ILENKRVVTLELSAVVAGTKYRGEFEERLRKLIDELTDSGEVIIFIDEIHTMIGAGAAEG
HHCCCCEEEEEEHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHCCCCCCC
AIDASNILKPALAKGELQCIGATTLDEYRKYIEKDSALERRFQPVTVDEPSKEATVEILK
CCCHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
GLRDRYEAHHRVQITDDAIEASVKMSDRYITDRYLPDKAIDLIDEAASNVKLKTNTAPPD
HHHHHHHCCCEEEEEHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHCCCEEECCCCCHH
MRKLEEDLEEIEKEKEAAVKSQDFEQAAKLRDKEQEIKKELEDMEKSWEKKQLSDEAQVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHCC
EEDIARIVSDWTGIPVKRLAQEETERLLNMEDALHQRVVGQEEAVQSVSNAIRRARSGLK
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCC
DPKRPIGSFIFLGPTGVGKTELARALADVLFGDEDAMIRLDMSEYMEKHTVSRLLGSPPG
CCCHHHCCEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHCCCCC
YVGHEESGQLTEKVRRRPYSVILLDEIEKAHPEVFNTLLQVLEDGRLTDAKGRTVDFRNT
CCCCCCCCHHHHHHHHCCCEEEEHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCEEEECCE
VIIMTSNVGANLIRNESKVGFKPQTSEDSYKEMKDNVMSELKNSFRPEFLNRVDEVIVFH
EEEEECCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
ALEKEHLSDIVELMLEELKERMAEFNMNLEFTEESKKHLAEQGYDPTYGARPLRRVIQKQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECHHHHHHHHHCCCCCCCCCHHHHHHHHHH
VEDVLSEKMLSGEFAHGETVVIDAEDNELSFKKK
HHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCC
>Mature Secondary Structure
MFARFTQRAQKVMALSQDEAKRLNHNYIGTEHLLLGLIREGEGIAAQTFKNLGVDLEEVR
CCCHHHHHHHHHHHHCHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHH
EAVENLVQPGEEQVSGNVGYTPRVKTVIELSMEEARRMGHNYIGTEHLLLGLVKEGEGIA
HHHHHHHCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHH
AKVLQELGVDLDKAREEVLKIIGGSQQPKGQANFGQAQNPKMANRDKTPTLDNFGRDLTK
HHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
LAEEGKLDPVIGRKKEIERVIQVLSRRTKNNPCLIGEPGVGKTAIAEGLAQKIIEGEVPK
HHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHCCCCHH
ILENKRVVTLELSAVVAGTKYRGEFEERLRKLIDELTDSGEVIIFIDEIHTMIGAGAAEG
HHCCCCEEEEEEHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHCCCCCCC
AIDASNILKPALAKGELQCIGATTLDEYRKYIEKDSALERRFQPVTVDEPSKEATVEILK
CCCHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
GLRDRYEAHHRVQITDDAIEASVKMSDRYITDRYLPDKAIDLIDEAASNVKLKTNTAPPD
HHHHHHHCCCEEEEEHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHCCCEEECCCCCHH
MRKLEEDLEEIEKEKEAAVKSQDFEQAAKLRDKEQEIKKELEDMEKSWEKKQLSDEAQVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHCC
EEDIARIVSDWTGIPVKRLAQEETERLLNMEDALHQRVVGQEEAVQSVSNAIRRARSGLK
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCC
DPKRPIGSFIFLGPTGVGKTELARALADVLFGDEDAMIRLDMSEYMEKHTVSRLLGSPPG
CCCHHHCCEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHCCCCC
YVGHEESGQLTEKVRRRPYSVILLDEIEKAHPEVFNTLLQVLEDGRLTDAKGRTVDFRNT
CCCCCCCCHHHHHHHHCCCEEEEHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCEEEECCE
VIIMTSNVGANLIRNESKVGFKPQTSEDSYKEMKDNVMSELKNSFRPEFLNRVDEVIVFH
EEEEECCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
ALEKEHLSDIVELMLEELKERMAEFNMNLEFTEESKKHLAEQGYDPTYGARPLRRVIQKQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECHHHHHHHHHCCCCCCCCCHHHHHHHHHH
VEDVLSEKMLSGEFAHGETVVIDAEDNELSFKKK
HHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]