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The map label for this gene is ctsR [H]

Identifier: 188584785

GI number: 188584785

Start: 166978

End: 167442

Strand: Direct

Name: ctsR [H]

Synonym: Nther_0143

Alternate gene names: 188584785

Gene position: 166978-167442 (Clockwise)

Preceding gene: 188584784

Following gene: 188584786

Centisome position: 5.27

GC content: 35.91

Gene sequence:

>465_bases
ATGGGAAGTCTTTCAGATAATATAGAAAAATACCTAAAAAATTTAATCGAAGAAAGTCCTAATAAAGCAATCGTAGTTAA
ACGTTGTGACCTGGCCTATAAGTTTAATTGTGTTCCATCTCAAATAAACTATGTATTGAGTACACGATTCACGGAAGATA
AAGGATATCTAGTGAGTAGTCGCCGTGGTGGTGGTGGATATATTGAAATCAGAAGATTGAGATTAGCTGGTGAGACTCCT
CTTTACAAACTAACTGATTTAATTGGAAACTCTATTTCTGAACAAGAGGCTAATGGTTTAATTACTCGATTGGCAGATGA
GGGAATTATCAAGGAACGCGAGGAAGGATTACTTAAAAGTTGTGTAAAAAGGGAAAGTATTCCTGTTCCTCTACCTTGGA
GAGACGAAATAAGGGCCGCTCTGTTTAAAAATGTATTGCTGGAGATACTAAAATTCAAGGAATAG

Upstream 100 bases:

>100_bases
AGTGTGTAGAGCTCAATTTTTATTTAATAATGTTGCAAAAAAAGGAAAAAAATTTTATAATAAGAATTGAAAGGTCAAAA
ATGGTCAGGGGTGAGATGGA

Downstream 100 bases:

>100_bases
TAAATTGTTAAGGCCTGTTTAGGAGGTGATTATTATGATGTGCCAAAATTGCAATAAACGTCCTGCCACTGTACATTGGA
CTAAAATTATCAATAACAAG

Product: transcriptional repressor, CtsR

Products: NA

Alternate protein names: Class three stress gene repressor [H]

Number of amino acids: Translated: 154; Mature: 153

Protein sequence:

>154_residues
MGSLSDNIEKYLKNLIEESPNKAIVVKRCDLAYKFNCVPSQINYVLSTRFTEDKGYLVSSRRGGGGYIEIRRLRLAGETP
LYKLTDLIGNSISEQEANGLITRLADEGIIKEREEGLLKSCVKRESIPVPLPWRDEIRAALFKNVLLEILKFKE

Sequences:

>Translated_154_residues
MGSLSDNIEKYLKNLIEESPNKAIVVKRCDLAYKFNCVPSQINYVLSTRFTEDKGYLVSSRRGGGGYIEIRRLRLAGETP
LYKLTDLIGNSISEQEANGLITRLADEGIIKEREEGLLKSCVKRESIPVPLPWRDEIRAALFKNVLLEILKFKE
>Mature_153_residues
GSLSDNIEKYLKNLIEESPNKAIVVKRCDLAYKFNCVPSQINYVLSTRFTEDKGYLVSSRRGGGGYIEIRRLRLAGETPL
YKLTDLIGNSISEQEANGLITRLADEGIIKEREEGLLKSCVKRESIPVPLPWRDEIRAALFKNVLLEILKFKE

Specific function: Controls the expression of the cellular protein quality control genes clpC, clpE and clpP. Acts as a repressor of these class III stress genes by binding to a directly repeated heptanucleotide operator sequence (A/GGTCAAA NAN A/GGTCAAA). After heat shock,

COG id: COG4463

COG function: function code K; Transcriptional repressor of class III stress genes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CtsR family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008463 [H]

Pfam domain/function: PF05848 CtsR [H]

EC number: NA

Molecular weight: Translated: 17491; Mature: 17359

Theoretical pI: Translated: 8.79; Mature: 8.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSLSDNIEKYLKNLIEESPNKAIVVKRCDLAYKFNCVPSQINYVLSTRFTEDKGYLVSS
CCCHHHHHHHHHHHHHHCCCCCEEEEEECCEEEEECCCHHHHHHHHHHEEECCCCEEEEC
RRGGGGYIEIRRLRLAGETPLYKLTDLIGNSISEQEANGLITRLADEGIIKEREEGLLKS
CCCCCCEEEEEEEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHH
CVKRESIPVPLPWRDEIRAALFKNVLLEILKFKE
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GSLSDNIEKYLKNLIEESPNKAIVVKRCDLAYKFNCVPSQINYVLSTRFTEDKGYLVSS
CCHHHHHHHHHHHHHHCCCCCEEEEEECCEEEEECCCHHHHHHHHHHEEECCCCEEEEC
RRGGGGYIEIRRLRLAGETPLYKLTDLIGNSISEQEANGLITRLADEGIIKEREEGLLKS
CCCCCCEEEEEEEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHH
CVKRESIPVPLPWRDEIRAALFKNVLLEILKFKE
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]