Definition Natranaerobius thermophilus JW/NM-WN-LF, complete genome.
Accession NC_010718
Length 3,165,557

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The map label for this gene is pncB [H]

Identifier: 188584695

GI number: 188584695

Start: 66478

End: 67518

Strand: Direct

Name: pncB [H]

Synonym: Nther_0053

Alternate gene names: 188584695

Gene position: 66478-67518 (Clockwise)

Preceding gene: 188584694

Following gene: 188584696

Centisome position: 2.1

GC content: 40.83

Gene sequence:

>1041_bases
ATGGATAGAATGGATTCTCTACATAATGTAGAGAAATGGGATCCTAAAACAAACCGAAGATTGTGGTCAGCGAATCACGA
AGAAATTATTAAAGGTGGTACAACTGATATATATTTTGTTCGTACCCAAGAAATTTTAAATCACATGAATTATGGTGATA
CTGAAGTGACAGTGGAGATTTTCCCATCACGGCCCGGTATAATGGCAGGAACAGAAGAAGCACTAGGTCTGATGGCTGAC
GCTCATAATTTAGAGATTTGGGCTCTTCCTGAAGGAGAAACCTTCGATAAAAAAGAGGTTATCATGAGGATTAAAGGTCC
TTATCAGGAAATAGGAATATATGAGACACCTTTGCTCGGTATATTAGCCTCCTCAGCTGGCTGGGCAGAAGCGGCCAGGG
AGTGTAGAGAAATTGTTGGAGAAGATAAACAACTGGTATGCTTCGGAGCACGTCATCTACATCCAGCAGTTGCACCAGTA
ATGGAAAGAGCTGCCCTTGTGGGAGGTTTTGACGGGTGTAGTTGTATTTTAGGAGCTAAATTGAAAGATCAGAAACCTAT
GGGTACTGTTCCCCATGCAGTATTCCTTATAGTAGGTGATACAGTGAGAGTAGCAGAAGCTTATCATCAAGCAATGCCAG
GTGAAGCTCCTCGAATAATTTTAGTTGACACCTTCAAAGATGAAGCCGAAGAAGCTCTTAGGGTAGCTAGGTCTTTAGAT
GATGATTTGGCAGGTGTTAGGTTAGATACTCCTTCAGAGCGAGGAGGTGTCACACCAGGGCTTGTCAGAGAAGTGAGAGC
CAGACTAAATCAAGAAGGATTTGATCATGTTAAAATATTAGCCTCTGGTGGAATGAACCCAGATAAAATTAGCCGTTTAA
TTGATGAAGGTGTTGATGCCTTTGGTGTAGGTAGTTATATAGCGAGGTCTAAGGCTAATGACATGACAATGGATATTAAA
GAGGTTAATGGTAAGCCTATTGCCAAAAGAGGTCGAATACCAGGAATAGTAAATAGTGAGAAATTATTAAAGATGAAATA
A

Upstream 100 bases:

>100_bases
ATTATGAACTTAAGTCGAGAAAAAAATTTCAAGAGAAGCTAAAAAATAGATACTGATATTGAATGGGATGTAAATAAACA
ATCAGAAAGGAGAAATGCTA

Downstream 100 bases:

>100_bases
GCACTTCTTTGAAGTGCTTATTTTTTTGCTCATTTGTATATGATTATTGGTTTTGGAAAAAATATAAATATCTATTAAAA
AAGTGGAGGCCTATGTCTAT

Product: nicotinate phosphoribosyltransferase

Products: NA

Alternate protein names: NAPRTase [H]

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MDRMDSLHNVEKWDPKTNRRLWSANHEEIIKGGTTDIYFVRTQEILNHMNYGDTEVTVEIFPSRPGIMAGTEEALGLMAD
AHNLEIWALPEGETFDKKEVIMRIKGPYQEIGIYETPLLGILASSAGWAEAARECREIVGEDKQLVCFGARHLHPAVAPV
MERAALVGGFDGCSCILGAKLKDQKPMGTVPHAVFLIVGDTVRVAEAYHQAMPGEAPRIILVDTFKDEAEEALRVARSLD
DDLAGVRLDTPSERGGVTPGLVREVRARLNQEGFDHVKILASGGMNPDKISRLIDEGVDAFGVGSYIARSKANDMTMDIK
EVNGKPIAKRGRIPGIVNSEKLLKMK

Sequences:

>Translated_346_residues
MDRMDSLHNVEKWDPKTNRRLWSANHEEIIKGGTTDIYFVRTQEILNHMNYGDTEVTVEIFPSRPGIMAGTEEALGLMAD
AHNLEIWALPEGETFDKKEVIMRIKGPYQEIGIYETPLLGILASSAGWAEAARECREIVGEDKQLVCFGARHLHPAVAPV
MERAALVGGFDGCSCILGAKLKDQKPMGTVPHAVFLIVGDTVRVAEAYHQAMPGEAPRIILVDTFKDEAEEALRVARSLD
DDLAGVRLDTPSERGGVTPGLVREVRARLNQEGFDHVKILASGGMNPDKISRLIDEGVDAFGVGSYIARSKANDMTMDIK
EVNGKPIAKRGRIPGIVNSEKLLKMK
>Mature_346_residues
MDRMDSLHNVEKWDPKTNRRLWSANHEEIIKGGTTDIYFVRTQEILNHMNYGDTEVTVEIFPSRPGIMAGTEEALGLMAD
AHNLEIWALPEGETFDKKEVIMRIKGPYQEIGIYETPLLGILASSAGWAEAARECREIVGEDKQLVCFGARHLHPAVAPV
MERAALVGGFDGCSCILGAKLKDQKPMGTVPHAVFLIVGDTVRVAEAYHQAMPGEAPRIILVDTFKDEAEEALRVARSLD
DDLAGVRLDTPSERGGVTPGLVREVRARLNQEGFDHVKILASGGMNPDKISRLIDEGVDAFGVGSYIARSKANDMTMDIK
EVNGKPIAKRGRIPGIVNSEKLLKMK

Specific function: Catalyzes the conversion of nicotinic acid (NA) to NA mononucleotide (NaMN) [H]

COG id: COG1488

COG function: function code H; Nicotinic acid phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAPRTase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015977
- InterPro:   IPR007229
- InterPro:   IPR006405
- InterPro:   IPR002638 [H]

Pfam domain/function: PF04095 NAPRTase [H]

EC number: =2.4.2.11 [H]

Molecular weight: Translated: 38038; Mature: 38038

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRMDSLHNVEKWDPKTNRRLWSANHEEIIKGGTTDIYFVRTQEILNHMNYGDTEVTVEI
CCCHHHHCCCHHCCCCCCCEEECCCHHHHHCCCCCEEEEEEHHHHHHHCCCCCCEEEEEE
FPSRPGIMAGTEEALGLMADAHNLEIWALPEGETFDKKEVIMRIKGPYQEIGIYETPLLG
ECCCCCCCCCCHHHHHHHCCCCCCEEEECCCCCCCCHHHHHEEECCCHHHCCCCCCCHHH
ILASSAGWAEAARECREIVGEDKQLVCFGARHLHPAVAPVMERAALVGGFDGCSCILGAK
HHHCCCCHHHHHHHHHHHHCCCCEEEEECCHHCCHHHHHHHHHHHHHCCCCCHHHEECCC
LKDQKPMGTVPHAVFLIVGDTVRVAEAYHQAMPGEAPRIILVDTFKDEAEEALRVARSLD
CCCCCCCCCCCCEEEEEECCHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHCC
DDLAGVRLDTPSERGGVTPGLVREVRARLNQEGFDHVKILASGGMNPDKISRLIDEGVDA
HHHCCEEECCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHCCCCC
FGVGSYIARSKANDMTMDIKEVNGKPIAKRGRIPGIVNSEKLLKMK
CCHHHHHHHCCCCCCEEEHHHCCCCCCHHCCCCCCCCCCCHHEECC
>Mature Secondary Structure
MDRMDSLHNVEKWDPKTNRRLWSANHEEIIKGGTTDIYFVRTQEILNHMNYGDTEVTVEI
CCCHHHHCCCHHCCCCCCCEEECCCHHHHHCCCCCEEEEEEHHHHHHHCCCCCCEEEEEE
FPSRPGIMAGTEEALGLMADAHNLEIWALPEGETFDKKEVIMRIKGPYQEIGIYETPLLG
ECCCCCCCCCCHHHHHHHCCCCCCEEEECCCCCCCCHHHHHEEECCCHHHCCCCCCCHHH
ILASSAGWAEAARECREIVGEDKQLVCFGARHLHPAVAPVMERAALVGGFDGCSCILGAK
HHHCCCCHHHHHHHHHHHHCCCCEEEEECCHHCCHHHHHHHHHHHHHCCCCCHHHEECCC
LKDQKPMGTVPHAVFLIVGDTVRVAEAYHQAMPGEAPRIILVDTFKDEAEEALRVARSLD
CCCCCCCCCCCCEEEEEECCHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHCC
DDLAGVRLDTPSERGGVTPGLVREVRARLNQEGFDHVKILASGGMNPDKISRLIDEGVDA
HHHCCEEECCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHCCCCC
FGVGSYIARSKANDMTMDIKEVNGKPIAKRGRIPGIVNSEKLLKMK
CCHHHHHHHCCCCCCEEEHHHCCCCCCHHCCCCCCCCCCCHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]