Definition | Natranaerobius thermophilus JW/NM-WN-LF, complete genome. |
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Accession | NC_010718 |
Length | 3,165,557 |
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The map label for this gene is pncB [H]
Identifier: 188584695
GI number: 188584695
Start: 66478
End: 67518
Strand: Direct
Name: pncB [H]
Synonym: Nther_0053
Alternate gene names: 188584695
Gene position: 66478-67518 (Clockwise)
Preceding gene: 188584694
Following gene: 188584696
Centisome position: 2.1
GC content: 40.83
Gene sequence:
>1041_bases ATGGATAGAATGGATTCTCTACATAATGTAGAGAAATGGGATCCTAAAACAAACCGAAGATTGTGGTCAGCGAATCACGA AGAAATTATTAAAGGTGGTACAACTGATATATATTTTGTTCGTACCCAAGAAATTTTAAATCACATGAATTATGGTGATA CTGAAGTGACAGTGGAGATTTTCCCATCACGGCCCGGTATAATGGCAGGAACAGAAGAAGCACTAGGTCTGATGGCTGAC GCTCATAATTTAGAGATTTGGGCTCTTCCTGAAGGAGAAACCTTCGATAAAAAAGAGGTTATCATGAGGATTAAAGGTCC TTATCAGGAAATAGGAATATATGAGACACCTTTGCTCGGTATATTAGCCTCCTCAGCTGGCTGGGCAGAAGCGGCCAGGG AGTGTAGAGAAATTGTTGGAGAAGATAAACAACTGGTATGCTTCGGAGCACGTCATCTACATCCAGCAGTTGCACCAGTA ATGGAAAGAGCTGCCCTTGTGGGAGGTTTTGACGGGTGTAGTTGTATTTTAGGAGCTAAATTGAAAGATCAGAAACCTAT GGGTACTGTTCCCCATGCAGTATTCCTTATAGTAGGTGATACAGTGAGAGTAGCAGAAGCTTATCATCAAGCAATGCCAG GTGAAGCTCCTCGAATAATTTTAGTTGACACCTTCAAAGATGAAGCCGAAGAAGCTCTTAGGGTAGCTAGGTCTTTAGAT GATGATTTGGCAGGTGTTAGGTTAGATACTCCTTCAGAGCGAGGAGGTGTCACACCAGGGCTTGTCAGAGAAGTGAGAGC CAGACTAAATCAAGAAGGATTTGATCATGTTAAAATATTAGCCTCTGGTGGAATGAACCCAGATAAAATTAGCCGTTTAA TTGATGAAGGTGTTGATGCCTTTGGTGTAGGTAGTTATATAGCGAGGTCTAAGGCTAATGACATGACAATGGATATTAAA GAGGTTAATGGTAAGCCTATTGCCAAAAGAGGTCGAATACCAGGAATAGTAAATAGTGAGAAATTATTAAAGATGAAATA A
Upstream 100 bases:
>100_bases ATTATGAACTTAAGTCGAGAAAAAAATTTCAAGAGAAGCTAAAAAATAGATACTGATATTGAATGGGATGTAAATAAACA ATCAGAAAGGAGAAATGCTA
Downstream 100 bases:
>100_bases GCACTTCTTTGAAGTGCTTATTTTTTTGCTCATTTGTATATGATTATTGGTTTTGGAAAAAATATAAATATCTATTAAAA AAGTGGAGGCCTATGTCTAT
Product: nicotinate phosphoribosyltransferase
Products: NA
Alternate protein names: NAPRTase [H]
Number of amino acids: Translated: 346; Mature: 346
Protein sequence:
>346_residues MDRMDSLHNVEKWDPKTNRRLWSANHEEIIKGGTTDIYFVRTQEILNHMNYGDTEVTVEIFPSRPGIMAGTEEALGLMAD AHNLEIWALPEGETFDKKEVIMRIKGPYQEIGIYETPLLGILASSAGWAEAARECREIVGEDKQLVCFGARHLHPAVAPV MERAALVGGFDGCSCILGAKLKDQKPMGTVPHAVFLIVGDTVRVAEAYHQAMPGEAPRIILVDTFKDEAEEALRVARSLD DDLAGVRLDTPSERGGVTPGLVREVRARLNQEGFDHVKILASGGMNPDKISRLIDEGVDAFGVGSYIARSKANDMTMDIK EVNGKPIAKRGRIPGIVNSEKLLKMK
Sequences:
>Translated_346_residues MDRMDSLHNVEKWDPKTNRRLWSANHEEIIKGGTTDIYFVRTQEILNHMNYGDTEVTVEIFPSRPGIMAGTEEALGLMAD AHNLEIWALPEGETFDKKEVIMRIKGPYQEIGIYETPLLGILASSAGWAEAARECREIVGEDKQLVCFGARHLHPAVAPV MERAALVGGFDGCSCILGAKLKDQKPMGTVPHAVFLIVGDTVRVAEAYHQAMPGEAPRIILVDTFKDEAEEALRVARSLD DDLAGVRLDTPSERGGVTPGLVREVRARLNQEGFDHVKILASGGMNPDKISRLIDEGVDAFGVGSYIARSKANDMTMDIK EVNGKPIAKRGRIPGIVNSEKLLKMK >Mature_346_residues MDRMDSLHNVEKWDPKTNRRLWSANHEEIIKGGTTDIYFVRTQEILNHMNYGDTEVTVEIFPSRPGIMAGTEEALGLMAD AHNLEIWALPEGETFDKKEVIMRIKGPYQEIGIYETPLLGILASSAGWAEAARECREIVGEDKQLVCFGARHLHPAVAPV MERAALVGGFDGCSCILGAKLKDQKPMGTVPHAVFLIVGDTVRVAEAYHQAMPGEAPRIILVDTFKDEAEEALRVARSLD DDLAGVRLDTPSERGGVTPGLVREVRARLNQEGFDHVKILASGGMNPDKISRLIDEGVDAFGVGSYIARSKANDMTMDIK EVNGKPIAKRGRIPGIVNSEKLLKMK
Specific function: Catalyzes the conversion of nicotinic acid (NA) to NA mononucleotide (NaMN) [H]
COG id: COG1488
COG function: function code H; Nicotinic acid phosphoribosyltransferase
Gene ontology:
Cell location: Cytoplasmic
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Belongs to the NAPRTase family [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR015977 - InterPro: IPR007229 - InterPro: IPR006405 - InterPro: IPR002638 [H]
Pfam domain/function: PF04095 NAPRTase [H]
EC number: =2.4.2.11 [H]
Molecular weight: Translated: 38038; Mature: 38038
Theoretical pI: Translated: 5.48; Mature: 5.48
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 3.8 %Met (Translated Protein) 4.9 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 3.8 %Met (Mature Protein) 4.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDRMDSLHNVEKWDPKTNRRLWSANHEEIIKGGTTDIYFVRTQEILNHMNYGDTEVTVEI CCCHHHHCCCHHCCCCCCCEEECCCHHHHHCCCCCEEEEEEHHHHHHHCCCCCCEEEEEE FPSRPGIMAGTEEALGLMADAHNLEIWALPEGETFDKKEVIMRIKGPYQEIGIYETPLLG ECCCCCCCCCCHHHHHHHCCCCCCEEEECCCCCCCCHHHHHEEECCCHHHCCCCCCCHHH ILASSAGWAEAARECREIVGEDKQLVCFGARHLHPAVAPVMERAALVGGFDGCSCILGAK HHHCCCCHHHHHHHHHHHHCCCCEEEEECCHHCCHHHHHHHHHHHHHCCCCCHHHEECCC LKDQKPMGTVPHAVFLIVGDTVRVAEAYHQAMPGEAPRIILVDTFKDEAEEALRVARSLD CCCCCCCCCCCCEEEEEECCHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHCC DDLAGVRLDTPSERGGVTPGLVREVRARLNQEGFDHVKILASGGMNPDKISRLIDEGVDA HHHCCEEECCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHCCCCC FGVGSYIARSKANDMTMDIKEVNGKPIAKRGRIPGIVNSEKLLKMK CCHHHHHHHCCCCCCEEEHHHCCCCCCHHCCCCCCCCCCCHHEECC >Mature Secondary Structure MDRMDSLHNVEKWDPKTNRRLWSANHEEIIKGGTTDIYFVRTQEILNHMNYGDTEVTVEI CCCHHHHCCCHHCCCCCCCEEECCCHHHHHCCCCCEEEEEEHHHHHHHCCCCCCEEEEEE FPSRPGIMAGTEEALGLMADAHNLEIWALPEGETFDKKEVIMRIKGPYQEIGIYETPLLG ECCCCCCCCCCHHHHHHHCCCCCCEEEECCCCCCCCHHHHHEEECCCHHHCCCCCCCHHH ILASSAGWAEAARECREIVGEDKQLVCFGARHLHPAVAPVMERAALVGGFDGCSCILGAK HHHCCCCHHHHHHHHHHHHCCCCEEEEECCHHCCHHHHHHHHHHHHHCCCCCHHHEECCC LKDQKPMGTVPHAVFLIVGDTVRVAEAYHQAMPGEAPRIILVDTFKDEAEEALRVARSLD CCCCCCCCCCCCEEEEEECCHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHCC DDLAGVRLDTPSERGGVTPGLVREVRARLNQEGFDHVKILASGGMNPDKISRLIDEGVDA HHHCCEEECCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHCCCCC FGVGSYIARSKANDMTMDIKEVNGKPIAKRGRIPGIVNSEKLLKMK CCHHHHHHHCCCCCCEEEHHHCCCCCCHHCCCCCCCCCCCHHEECC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9384377 [H]