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The map label for this gene is aspB [H]

Identifier: 188527480

GI number: 188527480

Start: 668413

End: 669585

Strand: Reverse

Name: aspB [H]

Synonym: HPSH_03500

Alternate gene names: 188527480

Gene position: 669585-668413 (Counterclockwise)

Preceding gene: 188527481

Following gene: 188527479

Centisome position: 41.63

GC content: 43.39

Gene sequence:

>1173_bases
ATGCCCTATTCCTCTAAAATCCAATCCCTTTCAGAATCCGCAACGATCGCTATTAGCACACTCGCTAAAGAATTGAAATC
GCAAGGAAAAGATATTTTAAGTTTTTCAGCGGGCGAGCCTGATTTTGACACCCCGCAAGCGATTAAAGATGCGGCCATAA
AAGCCCTAAATAATGGCTTTACCAAATACACTCCAGTGGCCGGGATCCCTGAATTATTAAAAGCGATCGCTCATAAATTG
AAAAAAGAAAACAACTTGGATTACGAACCGAATGAAATTCTAGTGAGCAATGGCGCTAAGCAAAGCTTGTTCAATGCGAT
TCAAGCCTTAATAGGGGATGGCGATGAAGTGATTATCCCTGTGCCTTTTTGGGTAACTTACCCTGAGCTTGTGAAATACA
GCGGTGGGGTGAGCAAATTCATTCAAACCGATGAGAAAAGCCATTTTAAAATCACCCCCAAGCAGCTTAAAGACGCCTTA
ACCCCCAAAACAAAAATGCTCATTCTCACCACCCCATCAAACCCTACCGGTATGCTTTATAGTAAGGCGGAGTTAGAGGC
TTTAGGCGAAGTTTTAAAAGACACTCCAATTTGGGTGCTTAGCGATGAAATTTATGAAAAGCTTGTTTATAAGGGGGAGT
TTGTTTCTTGCGCGGCGGTGAGTGAAGAGATGGAAAAACGCACCATTACCATTAACGGCTTGAGCAAGTCAGTAGCGATG
ACAGGCTGGCGTATGGGCTATGCGGCGAGCAAGGATAAAAAATTAGTCAAATTGATGAATAACTTGCAAAGCCAATGCAC
TTCCAATATCAATTCTATCACGCAAATGGCTTCTATCGTGGCGCTTGAAGGGTTGGTGGATAAAGAAATTGAAACGATGC
GTCAGGTTTTTGAGAAGCGCTGTCATTTAGCCCACGCAAAAATCAATGCGATTGAGGGGCTGAACGCTTTAAAACCTGAT
GGGGCGTTTTATCTTTTCATCAACATTAGCGGTCTTTGTGGGGGGGATTCGATGCGATTTTGCCATGAGTTATTGGAAAA
AGAAGGCGTGGCGTTAGTGCCTGGAAAGGCTTTTGGATTGGAAGGCTATGTGCGTTTGTCTTTTGCATGCTCAGAAGAAC
AGATTGAAAAGGGGATGGAACGCATCGCTCGCTTTGTCAAATCAAAAGGATAA

Upstream 100 bases:

>100_bases
CTTGCTTTCTTTTGAAATGTTTTTGAAAGTTTTTTGAAAATTAGAATTAAAATCTTTTTGATCATGTTATGATAGTTCAA
AAATTTAACAAGGATTAAGC

Downstream 100 bases:

>100_bases
AAGAATTTTATTTTAAAAGGGGGGATTTTATATTGTAGTTAGTGGCATAGTGGTGTAATGGTTAGATTTAAAAGTTTGAA
AAGTGTAGTTTTCATAACTA

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 390; Mature: 389

Protein sequence:

>390_residues
MPYSSKIQSLSESATIAISTLAKELKSQGKDILSFSAGEPDFDTPQAIKDAAIKALNNGFTKYTPVAGIPELLKAIAHKL
KKENNLDYEPNEILVSNGAKQSLFNAIQALIGDGDEVIIPVPFWVTYPELVKYSGGVSKFIQTDEKSHFKITPKQLKDAL
TPKTKMLILTTPSNPTGMLYSKAELEALGEVLKDTPIWVLSDEIYEKLVYKGEFVSCAAVSEEMEKRTITINGLSKSVAM
TGWRMGYAASKDKKLVKLMNNLQSQCTSNINSITQMASIVALEGLVDKEIETMRQVFEKRCHLAHAKINAIEGLNALKPD
GAFYLFINISGLCGGDSMRFCHELLEKEGVALVPGKAFGLEGYVRLSFACSEEQIEKGMERIARFVKSKG

Sequences:

>Translated_390_residues
MPYSSKIQSLSESATIAISTLAKELKSQGKDILSFSAGEPDFDTPQAIKDAAIKALNNGFTKYTPVAGIPELLKAIAHKL
KKENNLDYEPNEILVSNGAKQSLFNAIQALIGDGDEVIIPVPFWVTYPELVKYSGGVSKFIQTDEKSHFKITPKQLKDAL
TPKTKMLILTTPSNPTGMLYSKAELEALGEVLKDTPIWVLSDEIYEKLVYKGEFVSCAAVSEEMEKRTITINGLSKSVAM
TGWRMGYAASKDKKLVKLMNNLQSQCTSNINSITQMASIVALEGLVDKEIETMRQVFEKRCHLAHAKINAIEGLNALKPD
GAFYLFINISGLCGGDSMRFCHELLEKEGVALVPGKAFGLEGYVRLSFACSEEQIEKGMERIARFVKSKG
>Mature_389_residues
PYSSKIQSLSESATIAISTLAKELKSQGKDILSFSAGEPDFDTPQAIKDAAIKALNNGFTKYTPVAGIPELLKAIAHKLK
KENNLDYEPNEILVSNGAKQSLFNAIQALIGDGDEVIIPVPFWVTYPELVKYSGGVSKFIQTDEKSHFKITPKQLKDALT
PKTKMLILTTPSNPTGMLYSKAELEALGEVLKDTPIWVLSDEIYEKLVYKGEFVSCAAVSEEMEKRTITINGLSKSVAMT
GWRMGYAASKDKKLVKLMNNLQSQCTSNINSITQMASIVALEGLVDKEIETMRQVFEKRCHLAHAKINAIEGLNALKPDG
AFYLFINISGLCGGDSMRFCHELLEKEGVALVPGKAFGLEGYVRLSFACSEEQIEKGMERIARFVKSKG

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=422, Percent_Identity=28.1990521327014, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI56713256, Length=422, Percent_Identity=28.1990521327014, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI95147551, Length=420, Percent_Identity=26.1904761904762, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI169881279, Length=420, Percent_Identity=26.1904761904762, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI4507369, Length=380, Percent_Identity=24.4736842105263, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI169881281, Length=304, Percent_Identity=25.6578947368421, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI7705897, Length=426, Percent_Identity=24.4131455399061, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI33469970, Length=426, Percent_Identity=24.4131455399061, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI4885351, Length=343, Percent_Identity=23.6151603498542, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI19263340, Length=394, Percent_Identity=21.5736040609137, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI215599424, Length=394, Percent_Identity=21.5736040609137, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1786816, Length=387, Percent_Identity=26.8733850129199, Blast_Score=164, Evalue=6e-42,
Organism=Escherichia coli, GI1788627, Length=397, Percent_Identity=28.463476070529, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1788722, Length=400, Percent_Identity=25.5, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1790797, Length=312, Percent_Identity=22.1153846153846, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17567663, Length=372, Percent_Identity=25.8064516129032, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI71994476, Length=380, Percent_Identity=28.9473684210526, Blast_Score=127, Evalue=8e-30,
Organism=Caenorhabditis elegans, GI71994472, Length=380, Percent_Identity=28.9473684210526, Blast_Score=127, Evalue=8e-30,
Organism=Caenorhabditis elegans, GI17567369, Length=407, Percent_Identity=26.044226044226, Blast_Score=109, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6322401, Length=388, Percent_Identity=25, Blast_Score=139, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6323118, Length=374, Percent_Identity=23.2620320855615, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI28573069, Length=389, Percent_Identity=25.706940874036, Blast_Score=122, Evalue=6e-28,
Organism=Drosophila melanogaster, GI24646114, Length=389, Percent_Identity=25.706940874036, Blast_Score=122, Evalue=6e-28,
Organism=Drosophila melanogaster, GI28573067, Length=389, Percent_Identity=25.706940874036, Blast_Score=122, Evalue=6e-28,
Organism=Drosophila melanogaster, GI28573065, Length=389, Percent_Identity=25.706940874036, Blast_Score=122, Evalue=6e-28,
Organism=Drosophila melanogaster, GI18859735, Length=370, Percent_Identity=24.8648648648649, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24641770, Length=366, Percent_Identity=23.7704918032787, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24641760, Length=366, Percent_Identity=23.7704918032787, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24641768, Length=366, Percent_Identity=23.7704918032787, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24641766, Length=366, Percent_Identity=23.7704918032787, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24641764, Length=366, Percent_Identity=23.7704918032787, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI45551451, Length=366, Percent_Identity=23.7704918032787, Blast_Score=82, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 42848; Mature: 42717

Theoretical pI: Translated: 7.42; Mature: 7.42

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPYSSKIQSLSESATIAISTLAKELKSQGKDILSFSAGEPDFDTPQAIKDAAIKALNNGF
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCC
TKYTPVAGIPELLKAIAHKLKKENNLDYEPNEILVSNGAKQSLFNAIQALIGDGDEVIIP
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCEEEEE
VPFWVTYPELVKYSGGVSKFIQTDEKSHFKITPKQLKDALTPKTKMLILTTPSNPTGMLY
CCHHHCCHHHHHHCCCHHHHHHCCCCCCEEECHHHHHHHCCCCCEEEEEECCCCCCCCEE
SKAELEALGEVLKDTPIWVLSDEIYEKLVYKGEFVSCAAVSEEMEKRTITINGLSKSVAM
CHHHHHHHHHHHHCCCEEEECHHHHHHHHHCCCCHHHHHHHHHHHHCEEEEECCCHHHHH
TGWRMGYAASKDKKLVKLMNNLQSQCTSNINSITQMASIVALEGLVDKEIETMRQVFEKR
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CHLAHAKINAIEGLNALKPDGAFYLFINISGLCGGDSMRFCHELLEKEGVALVPGKAFGL
HHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCEEECCCCCCC
EGYVRLSFACSEEQIEKGMERIARFVKSKG
CCEEEEEEECCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PYSSKIQSLSESATIAISTLAKELKSQGKDILSFSAGEPDFDTPQAIKDAAIKALNNGF
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCC
TKYTPVAGIPELLKAIAHKLKKENNLDYEPNEILVSNGAKQSLFNAIQALIGDGDEVIIP
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCEEEEE
VPFWVTYPELVKYSGGVSKFIQTDEKSHFKITPKQLKDALTPKTKMLILTTPSNPTGMLY
CCHHHCCHHHHHHCCCHHHHHHCCCCCCEEECHHHHHHHCCCCCEEEEEECCCCCCCCEE
SKAELEALGEVLKDTPIWVLSDEIYEKLVYKGEFVSCAAVSEEMEKRTITINGLSKSVAM
CHHHHHHHHHHHHCCCEEEECHHHHHHHHHCCCCHHHHHHHHHHHHCEEEEECCCHHHHH
TGWRMGYAASKDKKLVKLMNNLQSQCTSNINSITQMASIVALEGLVDKEIETMRQVFEKR
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CHLAHAKINAIEGLNALKPDGAFYLFINISGLCGGDSMRFCHELLEKEGVALVPGKAFGL
HHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCEEECCCCCCC
EGYVRLSFACSEEQIEKGMERIARFVKSKG
CCEEEEEEECCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]