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The map label for this gene is mglB [H]

Identifier: 187935778

GI number: 187935778

Start: 2628288

End: 2629346

Strand: Reverse

Name: mglB [H]

Synonym: CLL_A2524

Alternate gene names: 187935778

Gene position: 2629346-2628288 (Counterclockwise)

Preceding gene: 187932767

Following gene: 187933460

Centisome position: 69.19

GC content: 25.78

Gene sequence:

>1059_bases
ATGAAAAAAAAACTTTTAAGTATTAATATGATAATTATAGTAATGATTTTAATGTTTTTTGGTGTTAATGAAAATATTGT
AGCTAATTGTTCAAATTTTGATTCAGAAAAAGCTGCTAAAGTAGGAGTATTGTTATATAAATTTAATGATGAGTATATCT
CTTTATTAAAAAATAGTTTGGAAGAAATTCAAAAAGAAAATCCAAACAAAGTTGAGTTTATTTTTTTAGATGCTTATGGT
GATGAAAAAAAACAAAATAAGGAACTAGATAAATTGTTAAAAGAAAAAGTAGATCTTTTATTAGTAAACTTAGTTGATAC
AAGTGAAGGATCAACACAAAAAGTAGTGGATAGAATTAAAGAAAATAATGTTCCAGTAATATTTTTTAATAGGGAACCTA
TAAGTAAAATACCAATAAAATCTTATGAGAAAGCTGTTATTTTATCAAGAATACCCGAGGCAGGCATATTACAAGGGCAA
ATAGTATCTGACTTATGGAATGATAATAAAAAAATGATAGATAAAAACAAAGATAATATTATGCAATATGTTATGTTAAC
TGGTGAAAGTAGTGACTTAACGGCAATTTCTAGAACTAAAAATGTTATTAAAACAATAAAAGACAATGGAATAGAAATTC
AAGAATTAGAAAAGAAAAATTCCAAGTGGGATAGAGAATTAGCTAAGCAAAATATAGCATCATTATTATATCAATACGGT
AATAAAATTGAAGTTATAATTGCTAATAATGATGCTATGGCAATAGGTGCTATTGAAGCATTGCAAAAGCAAAATTATAA
TAACGGAGATTTGAATAATACAATTATTGTTGTAGGAATTGATGCAACACCTAAAGCAAAGGAATTAATAAATGAGGGTT
ATATGGCTGGAACAGTTTTTCAAGATCCAAAAGAAGAAGCAGATGCCCTTTATACTTTAGGAATGAATTTAATATCAGGT
AAAAATCCAATTGAAAATACACAATATAAGTATGATGAGACAGGAGTTACAGTTCGCCTTCCATATAAAGAATATATTAA
TGAAACAAAGTATAAGTAA

Upstream 100 bases:

>100_bases
GCTTATTTTTATTCTTATGGATAATTTATTTTCATAATCCAAATAATATTAATAGTAAAAATATTTATGAAATATAAAAT
TAGTATAACGGAGGATTACT

Downstream 100 bases:

>100_bases
ATCTAAATTTTAATAAGTTTAAAGAATAAAATATTTTTATAAACACATTATAATTAATGAGTGAGGTGAATTTTAATGGA
TAACAATAAAAATAGATTAA

Product: D-galactose-binding periplasmic protein

Products: ADP; phosphate; beta-D-galactose [Cytoplasm] [C]

Alternate protein names: GBP; D-galactose/ D-glucose-binding protein; GGBP [H]

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MKKKLLSINMIIIVMILMFFGVNENIVANCSNFDSEKAAKVGVLLYKFNDEYISLLKNSLEEIQKENPNKVEFIFLDAYG
DEKKQNKELDKLLKEKVDLLLVNLVDTSEGSTQKVVDRIKENNVPVIFFNREPISKIPIKSYEKAVILSRIPEAGILQGQ
IVSDLWNDNKKMIDKNKDNIMQYVMLTGESSDLTAISRTKNVIKTIKDNGIEIQELEKKNSKWDRELAKQNIASLLYQYG
NKIEVIIANNDAMAIGAIEALQKQNYNNGDLNNTIIVVGIDATPKAKELINEGYMAGTVFQDPKEEADALYTLGMNLISG
KNPIENTQYKYDETGVTVRLPYKEYINETKYK

Sequences:

>Translated_352_residues
MKKKLLSINMIIIVMILMFFGVNENIVANCSNFDSEKAAKVGVLLYKFNDEYISLLKNSLEEIQKENPNKVEFIFLDAYG
DEKKQNKELDKLLKEKVDLLLVNLVDTSEGSTQKVVDRIKENNVPVIFFNREPISKIPIKSYEKAVILSRIPEAGILQGQ
IVSDLWNDNKKMIDKNKDNIMQYVMLTGESSDLTAISRTKNVIKTIKDNGIEIQELEKKNSKWDRELAKQNIASLLYQYG
NKIEVIIANNDAMAIGAIEALQKQNYNNGDLNNTIIVVGIDATPKAKELINEGYMAGTVFQDPKEEADALYTLGMNLISG
KNPIENTQYKYDETGVTVRLPYKEYINETKYK
>Mature_352_residues
MKKKLLSINMIIIVMILMFFGVNENIVANCSNFDSEKAAKVGVLLYKFNDEYISLLKNSLEEIQKENPNKVEFIFLDAYG
DEKKQNKELDKLLKEKVDLLLVNLVDTSEGSTQKVVDRIKENNVPVIFFNREPISKIPIKSYEKAVILSRIPEAGILQGQ
IVSDLWNDNKKMIDKNKDNIMQYVMLTGESSDLTAISRTKNVIKTIKDNGIEIQELEKKNSKWDRELAKQNIASLLYQYG
NKIEVIIANNDAMAIGAIEALQKQNYNNGDLNNTIIVVGIDATPKAKELINEGYMAGTVFQDPKEEADALYTLGMNLISG
KNPIENTQYKYDETGVTVRLPYKEYINETKYK

Specific function: This protein is involved in the active transport of galactose and glucose. It plays a role in the chemotaxis towards the two sugars by interacting with the trg chemoreceptor [H]

COG id: COG1879

COG function: function code G; ABC-type sugar transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 2 family [H]

Homologues:

Organism=Escherichia coli, GI1788473, Length=344, Percent_Identity=37.5, Blast_Score=211, Evalue=4e-56,
Organism=Escherichia coli, GI1790192, Length=299, Percent_Identity=21.7391304347826, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 4720 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 1320 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001761 [H]

Pfam domain/function: PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 40012; Mature: 40012

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKLLSINMIIIVMILMFFGVNENIVANCSNFDSEKAAKVGVLLYKFNDEYISLLKNSL
CCCCHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHEEEEEEEECHHHHHHHHHHH
EEIQKENPNKVEFIFLDAYGDEKKQNKELDKLLKEKVDLLLVNLVDTSEGSTQKVVDRIK
HHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHEEEEEEEECCCCCHHHHHHHHH
ENNVPVIFFNREPISKIPIKSYEKAVILSRIPEAGILQGQIVSDLWNDNKKMIDKNKDNI
HCCCCEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHCCCHHHE
MQYVMLTGESSDLTAISRTKNVIKTIKDNGIEIQELEKKNSKWDRELAKQNIASLLYQYG
EEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHC
NKIEVIIANNDAMAIGAIEALQKQNYNNGDLNNTIIVVGIDATPKAKELINEGYMAGTVF
CEEEEEEECCCCEEHHHHHHHHHCCCCCCCCCCEEEEEEECCCCHHHHHHHCCCEECCCC
QDPKEEADALYTLGMNLISGKNPIENTQYKYDETGVTVRLPYKEYINETKYK
CCCHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCEEEEECHHHHHHHCCCC
>Mature Secondary Structure
MKKKLLSINMIIIVMILMFFGVNENIVANCSNFDSEKAAKVGVLLYKFNDEYISLLKNSL
CCCCHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHEEEEEEEECHHHHHHHHHHH
EEIQKENPNKVEFIFLDAYGDEKKQNKELDKLLKEKVDLLLVNLVDTSEGSTQKVVDRIK
HHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHEEEEEEEECCCCCHHHHHHHHH
ENNVPVIFFNREPISKIPIKSYEKAVILSRIPEAGILQGQIVSDLWNDNKKMIDKNKDNI
HCCCCEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHCCCHHHE
MQYVMLTGESSDLTAISRTKNVIKTIKDNGIEIQELEKKNSKWDRELAKQNIASLLYQYG
EEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHC
NKIEVIIANNDAMAIGAIEALQKQNYNNGDLNNTIIVVGIDATPKAKELINEGYMAGTVF
CEEEEEEECCCCEEHHHHHHHHHCCCCCCCCCCEEEEEEECCCCHHHHHHHCCCEECCCC
QDPKEEADALYTLGMNLISGKNPIENTQYKYDETGVTVRLPYKEYINETKYK
CCCHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCEEEEECHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; beta-D-galactose [Periplasm]; H2O [C]

Specific reaction: ATP + beta-D-galactose [Periplasm] + H2O = ADP + phosphate + beta-D-galactose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA