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The map label for this gene is yisY [H]

Identifier: 187935377

GI number: 187935377

Start: 2229227

End: 2230042

Strand: Reverse

Name: yisY [H]

Synonym: CLL_A2130

Alternate gene names: 187935377

Gene position: 2230042-2229227 (Counterclockwise)

Preceding gene: 187933749

Following gene: 187935741

Centisome position: 58.68

GC content: 34.56

Gene sequence:

>816_bases
ATGGGATATTATGTTAGAGTAGAATCAGATGTAAAAGTTTATGTAGAGGATCTTAATCCAGAGGGCAAAAAAACAATCGT
ATTTCTACATGGGTGGCCTGGAAGTCATAAACTGTTTGAGTATCAGTTTAATCAACTACCTAAAATGGGATATCGATGTA
TTGGCATAGATCAGAGAGGATTTGGACAATCAGACAAGCCTTTTACAGGATATTGCTACGATAGGTTATCAGATGATGTT
CGAGCTGTAGTTGAAGTACTTAATTTAAAAAATTTTATATTAGCAGGACATTCTACTGGGGGAGCCATTGCTATTAGATA
CATGGCCAGACATAATGAATATGGAGTGTCTAAACTTGCACTTTTTGCAGCAGCAGCTCCTAGTCTTATAAAACGTCCAT
ATTTTCCATATGGTTTAGAAAAAGAAGCTGTAAATGAAATTATTCAAGGAACATATAATGATCGTCCTAAAATGTTGCAA
GGATTTGGAGACATGTTTTTCTTCCAGCATATAACTAAGCCTTTTTCAGACTGGTTCTTCCAATTAGGATTACAAGCAGC
AGGCTGGGCAACTGCTGCAACTGCAAATTCTTGGTTAGATGAAGAAAGCTTATTTTTTGATCTAGAGAAAATAAGTGTTC
CAACTTTAATTCTTCATGGTATTCATGACAAAGTTTGTCTATTCCCATTAGCTGAATCACAAAGACAACGTATTAAAAAT
TCCAAGCTTATAGCATTTGAAGACAGTGGCCATGGATTATTCTATGATCAACGTGATAAATTTAATGAAGAATTGACACA
ATTTATTGAAGAATAA

Upstream 100 bases:

>100_bases
GCTTGAACGAAATTATATTAAAATCAAATATGTGATTCACCTATTTGTTCCACAGAGAATAAGCTGATAATGAAGAAATT
TTATTAAAAGAGGTATTTGA

Downstream 100 bases:

>100_bases
AGTTTTTGTATCTATTGATTTGCCTAGAATAGTAGAAATCGAAATATATAATTTAAAAAAACAGGAATTTGTAGTGGGGA
TTATTAAGGATGATGAGGAA

Product: alpha/beta superfamily hydrolase

Products: 2-oxopent-4-enoate; succinate [C]

Alternate protein names: NA

Number of amino acids: Translated: 271; Mature: 270

Protein sequence:

>271_residues
MGYYVRVESDVKVYVEDLNPEGKKTIVFLHGWPGSHKLFEYQFNQLPKMGYRCIGIDQRGFGQSDKPFTGYCYDRLSDDV
RAVVEVLNLKNFILAGHSTGGAIAIRYMARHNEYGVSKLALFAAAAPSLIKRPYFPYGLEKEAVNEIIQGTYNDRPKMLQ
GFGDMFFFQHITKPFSDWFFQLGLQAAGWATAATANSWLDEESLFFDLEKISVPTLILHGIHDKVCLFPLAESQRQRIKN
SKLIAFEDSGHGLFYDQRDKFNEELTQFIEE

Sequences:

>Translated_271_residues
MGYYVRVESDVKVYVEDLNPEGKKTIVFLHGWPGSHKLFEYQFNQLPKMGYRCIGIDQRGFGQSDKPFTGYCYDRLSDDV
RAVVEVLNLKNFILAGHSTGGAIAIRYMARHNEYGVSKLALFAAAAPSLIKRPYFPYGLEKEAVNEIIQGTYNDRPKMLQ
GFGDMFFFQHITKPFSDWFFQLGLQAAGWATAATANSWLDEESLFFDLEKISVPTLILHGIHDKVCLFPLAESQRQRIKN
SKLIAFEDSGHGLFYDQRDKFNEELTQFIEE
>Mature_270_residues
GYYVRVESDVKVYVEDLNPEGKKTIVFLHGWPGSHKLFEYQFNQLPKMGYRCIGIDQRGFGQSDKPFTGYCYDRLSDDVR
AVVEVLNLKNFILAGHSTGGAIAIRYMARHNEYGVSKLALFAAAAPSLIKRPYFPYGLEKEAVNEIIQGTYNDRPKMLQG
FGDMFFFQHITKPFSDWFFQLGLQAAGWATAATANSWLDEESLFFDLEKISVPTLILHGIHDKVCLFPLAESQRQRIKNS
KLIAFEDSGHGLFYDQRDKFNEELTQFIEE

Specific function: 3-hydroxyphenylpropionate degradation. [C]

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily [H]

Homologues:

Organism=Caenorhabditis elegans, GI17554012, Length=293, Percent_Identity=22.8668941979522, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: 3.7.1.- [C]

Molecular weight: Translated: 31041; Mature: 30909

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYYVRVESDVKVYVEDLNPEGKKTIVFLHGWPGSHKLFEYQFNQLPKMGYRCIGIDQRG
CCEEEEECCCEEEEEECCCCCCCEEEEEEECCCCCCCHHHHHHHCCCCCCCEEEECCCCC
FGQSDKPFTGYCYDRLSDDVRAVVEVLNLKNFILAGHSTGGAIAIRYMARHNEYGVSKLA
CCCCCCCCCCHHHHHCCHHHHHHHHHHCCHHEEEECCCCCCEEEEEEEHHCCCCCHHHHH
LFAAAAPSLIKRPYFPYGLEKEAVNEIIQGTYNDRPKMLQGFGDMFFFQHITKPFSDWFF
HHHHHCHHHHHCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QLGLQAAGWATAATANSWLDEESLFFDLEKISVPTLILHGIHDKVCLFPLAESQRQRIKN
HHCCCCCCCCHHHHHHHCCCCHHHEEEHHHHCCCHHEEECCCCCEEEEECCHHHHHHHCC
SKLIAFEDSGHGLFYDQRDKFNEELTQFIEE
CCEEEEECCCCCCEECCHHHHHHHHHHHHCC
>Mature Secondary Structure 
GYYVRVESDVKVYVEDLNPEGKKTIVFLHGWPGSHKLFEYQFNQLPKMGYRCIGIDQRG
CEEEEECCCEEEEEECCCCCCCEEEEEEECCCCCCCHHHHHHHCCCCCCCEEEECCCCC
FGQSDKPFTGYCYDRLSDDVRAVVEVLNLKNFILAGHSTGGAIAIRYMARHNEYGVSKLA
CCCCCCCCCCHHHHHCCHHHHHHHHHHCCHHEEEECCCCCCEEEEEEEHHCCCCCHHHHH
LFAAAAPSLIKRPYFPYGLEKEAVNEIIQGTYNDRPKMLQGFGDMFFFQHITKPFSDWFF
HHHHHCHHHHHCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QLGLQAAGWATAATANSWLDEESLFFDLEKISVPTLILHGIHDKVCLFPLAESQRQRIKN
HHCCCCCCCCHHHHHHHCCCCHHHEEEHHHHCCCHHEEECCCCCEEEEECCHHHHHHHCC
SKLIAFEDSGHGLFYDQRDKFNEELTQFIEE
CCEEEEECCCCCCEECCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-hydroxy-6-ketononadienedicarboxylate; H2O [C]

Specific reaction: 2-hydroxy-6-ketononadienedicarboxylate + H2O = 2-oxopent-4-enoate + succinate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353931; 9384377 [H]