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The map label for this gene is dusC [H]

Identifier: 187935292

GI number: 187935292

Start: 2214622

End: 2215587

Strand: Reverse

Name: dusC [H]

Synonym: CLL_A2117

Alternate gene names: 187935292

Gene position: 2215587-2214622 (Counterclockwise)

Preceding gene: 187933963

Following gene: 187935398

Centisome position: 58.3

GC content: 25.78

Gene sequence:

>966_bases
ATGAAATATTATTTAGCACCAATGGAAGGAATCACTGGATACATATATAGAAATTCTTATGAAAAATTTTTTAATAATAT
TGACAAATACTTTACACCATTTATTGTTACAAATAAAAGTAGAAGTCTTAAAACTAAAGAATTAAGGGATGTTTTGCCTG
AAAATAATAATGGGATGAATATAGTGCCTCAAATACTTACTAATGATTCAGAAGGGTTTATTAATACTTCTGGAAAGTTA
AAACAATTAGGTTATAATGAAGTTAATTTAAATTTAGGCTGTCCTGCTGGAACTGTTGTTTCAAAAAATAGAGGCTCAGG
ATTTCTAGCCAAAAGAGAAGAATTGGACATGTTCTTAGATGAAATATTTAAAATGGATGATATTAAAATTTCCATAAAAA
CTAGAATAGGAAAGGATAGTCCGGAAGAATTTTATGAGCTGATAAAAATTTACAATAAATATCCTATTGAAGAATTAATT
ATTCATCCTAGAACACAAAAAGATTTTTATGGAAATAAACCCAATTTAGACGTATTTAAAGATGCATTATCATTAAGTAA
CAATCCAATATGTTACAATGGTGATATTTTCACTGTGAAAGATCATGATAAATTAACAAGAGATTTTCCAGAAGTTAAAA
CATTAATGCTTGGAAGAGGTATATTAGCCAATCCGGGGTTAATGAATGAGATTAAAAATAATACTTTTATAGATAAAGAA
ATATTAAAAGAGTTTCATGATGAAATTTTAAGTAAATATATAGAGTTATTTAATGAAGATAGGAATGCAATATTTAGAAT
GAAAGAATTATGGGGATACATGATTTACATGTTTTCAGATAATAAAAAATACGCTAAAAAAATAAAGAAGGCACAAAAAT
TAAGTGATTATAATGAAACTGTCTTAAGTTTATTTACGGAGCAGGAAATTATAAAAGGGGCTGGATTATTTAATAATCAA
TATTAA

Upstream 100 bases:

>100_bases
GTTTATAAAGGAATAATAGTGTGGGAAATTAAATACAGTTATAGTAATTTAAATATTACTTTTATAAGCAAATACAACTT
AGATTATAAGGAGTCATTAA

Downstream 100 bases:

>100_bases
AAGTGATATGTTTTATTAAATAAACATGACAAAGAAGAGCAAGATAATAAAACAAGTTTATGCTATTAATGATTTTATGT
AGAGGTATTATCTTTATTAT

Product: dihydrouridine synthase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MKYYLAPMEGITGYIYRNSYEKFFNNIDKYFTPFIVTNKSRSLKTKELRDVLPENNNGMNIVPQILTNDSEGFINTSGKL
KQLGYNEVNLNLGCPAGTVVSKNRGSGFLAKREELDMFLDEIFKMDDIKISIKTRIGKDSPEEFYELIKIYNKYPIEELI
IHPRTQKDFYGNKPNLDVFKDALSLSNNPICYNGDIFTVKDHDKLTRDFPEVKTLMLGRGILANPGLMNEIKNNTFIDKE
ILKEFHDEILSKYIELFNEDRNAIFRMKELWGYMIYMFSDNKKYAKKIKKAQKLSDYNETVLSLFTEQEIIKGAGLFNNQ
Y

Sequences:

>Translated_321_residues
MKYYLAPMEGITGYIYRNSYEKFFNNIDKYFTPFIVTNKSRSLKTKELRDVLPENNNGMNIVPQILTNDSEGFINTSGKL
KQLGYNEVNLNLGCPAGTVVSKNRGSGFLAKREELDMFLDEIFKMDDIKISIKTRIGKDSPEEFYELIKIYNKYPIEELI
IHPRTQKDFYGNKPNLDVFKDALSLSNNPICYNGDIFTVKDHDKLTRDFPEVKTLMLGRGILANPGLMNEIKNNTFIDKE
ILKEFHDEILSKYIELFNEDRNAIFRMKELWGYMIYMFSDNKKYAKKIKKAQKLSDYNETVLSLFTEQEIIKGAGLFNNQ
Y
>Mature_321_residues
MKYYLAPMEGITGYIYRNSYEKFFNNIDKYFTPFIVTNKSRSLKTKELRDVLPENNNGMNIVPQILTNDSEGFINTSGKL
KQLGYNEVNLNLGCPAGTVVSKNRGSGFLAKREELDMFLDEIFKMDDIKISIKTRIGKDSPEEFYELIKIYNKYPIEELI
IHPRTQKDFYGNKPNLDVFKDALSLSNNPICYNGDIFTVKDHDKLTRDFPEVKTLMLGRGILANPGLMNEIKNNTFIDKE
ILKEFHDEILSKYIELFNEDRNAIFRMKELWGYMIYMFSDNKKYAKKIKKAQKLSDYNETVLSLFTEQEIIKGAGLFNNQ
Y

Specific function: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs [H]

COG id: COG0042

COG function: function code J; tRNA-dihydrouridine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dus family. DusC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788462, Length=297, Percent_Identity=24.2424242424242, Blast_Score=76, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001269
- InterPro:   IPR018517 [H]

Pfam domain/function: PF01207 Dus [H]

EC number: NA

Molecular weight: Translated: 37433; Mature: 37433

Theoretical pI: Translated: 8.11; Mature: 8.11

Prosite motif: PS01136 UPF0034

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYYLAPMEGITGYIYRNSYEKFFNNIDKYFTPFIVTNKSRSLKTKELRDVLPENNNGMN
CCEEECCCCCCEEEEECCCHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHCCCCCCCCE
IVPQILTNDSEGFINTSGKLKQLGYNEVNLNLGCPAGTVVSKNRGSGFLAKREELDMFLD
EEHHHHCCCCCCEEECCCCHHHCCCCEEEEEECCCCCCEEECCCCCCCCHHHHHHHHHHH
EIFKMDDIKISIKTRIGKDSPEEFYELIKIYNKYPIEELIIHPRTQKDFYGNKPNLDVFK
HHHCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCHHHHH
DALSLSNNPICYNGDIFTVKDHDKLTRDFPEVKTLMLGRGILANPGLMNEIKNNTFIDKE
HHHHCCCCCEEECCCEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCHH
ILKEFHDEILSKYIELFNEDRNAIFRMKELWGYMIYMFSDNKKYAKKIKKAQKLSDYNET
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCEEEEEEECCHHHHHHHHHHHHHHHHHHH
VLSLFTEQEIIKGAGLFNNQY
HHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKYYLAPMEGITGYIYRNSYEKFFNNIDKYFTPFIVTNKSRSLKTKELRDVLPENNNGMN
CCEEECCCCCCEEEEECCCHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHCCCCCCCCE
IVPQILTNDSEGFINTSGKLKQLGYNEVNLNLGCPAGTVVSKNRGSGFLAKREELDMFLD
EEHHHHCCCCCCEEECCCCHHHCCCCEEEEEECCCCCCEEECCCCCCCCHHHHHHHHHHH
EIFKMDDIKISIKTRIGKDSPEEFYELIKIYNKYPIEELIIHPRTQKDFYGNKPNLDVFK
HHHCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCHHHHH
DALSLSNNPICYNGDIFTVKDHDKLTRDFPEVKTLMLGRGILANPGLMNEIKNNTFIDKE
HHHHCCCCCEEECCCEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCHH
ILKEFHDEILSKYIELFNEDRNAIFRMKELWGYMIYMFSDNKKYAKKIKKAQKLSDYNET
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCEEEEEEECCHHHHHHHHHHHHHHHHHHH
VLSLFTEQEIIKGAGLFNNQY
HHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]