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The map label for this gene is yicO [C]

Identifier: 187935209

GI number: 187935209

Start: 2726438

End: 2727778

Strand: Reverse

Name: yicO [C]

Synonym: CLL_A2616

Alternate gene names: 187935209

Gene position: 2727778-2726438 (Counterclockwise)

Preceding gene: 187934893

Following gene: 187933218

Centisome position: 71.78

GC content: 31.32

Gene sequence:

>1341_bases
ATGATTGAAATTAAACAAAAGGATTGTAATAATAACAGTATTTTGGAAAAATTTTTTAAGTTAACTGAAAAGGGAACAGA
TGTAAAGACCGAAATATTAGCAGGAGCAACAACATTTATAGCAACAGCATATATTTTAGCAGTTATACCTAGTATGCTCT
GTACAACAGGAATGCCGCAAACTAGTACAGTAGCAGCGGTAGTTTTAACAACGGCATTTGCGACAATATTTATGGGGATG
TTTGCAAATTTACCAGTTGTAGTTGCACCAGGATTAGGATTAAGTGCTTTTTTTGCATATACTATTTGTGGAGCAATGGG
GTTACCATGGCAAACAGCATTAGGTGCAGTTTTTATTTCAGGGGTAGTATTTATAATTTTAACAGTAACTAAGGTATTAC
AACGTATTATAGATTCTATTCCAGATGTTTTAAAAACATCTATAGGGGTTGGTATAGGATTATTTATAGCGTTTATAGGA
CTAAAAAATTCTCAAATTATTGTTGCCAATCAATCTACTTTTGTTGGACTTGGTAATATAAAAGATCCAGGAGTAATTCT
TACATTTTTTGGATTGATTTTTACAGCAGCTTTATTTTCAAGAAGGGTTAAAGGTAGTTTATTAATTGGAATGTTTACCA
CAACAATAGTGGGAATGTTTATTGGAATAACTAAAATTCCACATAGCATAGGAGATATATTTAATTTAGTTCCACCTATT
CCAGTAGATACATTTGGTAAATTAGATATTATGGGAGCAGTAAAATACGGACTTGTATCAATAGTGTTTTCAATAACAAT
TGTTGATATGTTTGATAATATTGGAACACTAATTGGAGTATCAAAAAAAGCTGGTTTAGTTAAAGAAGATGGAAGTATTG
AAGGATTAGATAAAGCATTAGTTACAGGTTCAGTGGCAGCAGCAACAGGAGCATTACTTGGAACTTGTACTGTTACATCA
TATGTAGAAAGTGCTACAGGAGTAGCAGAAGGTGGTAGAACTGGTTTAACAGCTGTTACAACAGGAATTCTATTTCTAGT
AGCATTATTCTTTGCACCATTATTTATGTTAGTTCCTCCACAAGCTACAGCACCAGTTTTAATTATAGTAGGTGTTCTTA
TGCTTGGTGAAGTTACTAGTATAAATTTTAATGATTTTACTGAAGCACTACCAGGATTTATAACTATACTTCTTATGCCA
CTTACTTTTAGTATAGCTCAAGGATTAGCAATGGGATTCATTAGTTACACTTTAATTAAAGTATTAACAGGTAAACAAAA
GGAAATAAAACCTATTATGTATATACTTACAATAGCATTTGTTATACATTTTATTATTTAA

Upstream 100 bases:

>100_bases
TTTTATTAAGATTTTTTAACTACCATTTGATTAAGTAATTGATTAAGTATTAATCATTTTCTTATAAAGAAATAAGTTAA
ATTTCATAGGGGGATTAAAA

Downstream 100 bases:

>100_bases
GATTATTATAATATTAAGAAGAATCTTAGAATTTAATAATCTTAGAACTTAGGAATTTAAGAATATTAGAATTTAAGAAC
TTAAGAATTTGCTGATAAAA

Product: inner membrane protein YicO

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MIEIKQKDCNNNSILEKFFKLTEKGTDVKTEILAGATTFIATAYILAVIPSMLCTTGMPQTSTVAAVVLTTAFATIFMGM
FANLPVVVAPGLGLSAFFAYTICGAMGLPWQTALGAVFISGVVFIILTVTKVLQRIIDSIPDVLKTSIGVGIGLFIAFIG
LKNSQIIVANQSTFVGLGNIKDPGVILTFFGLIFTAALFSRRVKGSLLIGMFTTTIVGMFIGITKIPHSIGDIFNLVPPI
PVDTFGKLDIMGAVKYGLVSIVFSITIVDMFDNIGTLIGVSKKAGLVKEDGSIEGLDKALVTGSVAAATGALLGTCTVTS
YVESATGVAEGGRTGLTAVTTGILFLVALFFAPLFMLVPPQATAPVLIIVGVLMLGEVTSINFNDFTEALPGFITILLMP
LTFSIAQGLAMGFISYTLIKVLTGKQKEIKPIMYILTIAFVIHFII

Sequences:

>Translated_446_residues
MIEIKQKDCNNNSILEKFFKLTEKGTDVKTEILAGATTFIATAYILAVIPSMLCTTGMPQTSTVAAVVLTTAFATIFMGM
FANLPVVVAPGLGLSAFFAYTICGAMGLPWQTALGAVFISGVVFIILTVTKVLQRIIDSIPDVLKTSIGVGIGLFIAFIG
LKNSQIIVANQSTFVGLGNIKDPGVILTFFGLIFTAALFSRRVKGSLLIGMFTTTIVGMFIGITKIPHSIGDIFNLVPPI
PVDTFGKLDIMGAVKYGLVSIVFSITIVDMFDNIGTLIGVSKKAGLVKEDGSIEGLDKALVTGSVAAATGALLGTCTVTS
YVESATGVAEGGRTGLTAVTTGILFLVALFFAPLFMLVPPQATAPVLIIVGVLMLGEVTSINFNDFTEALPGFITILLMP
LTFSIAQGLAMGFISYTLIKVLTGKQKEIKPIMYILTIAFVIHFII
>Mature_446_residues
MIEIKQKDCNNNSILEKFFKLTEKGTDVKTEILAGATTFIATAYILAVIPSMLCTTGMPQTSTVAAVVLTTAFATIFMGM
FANLPVVVAPGLGLSAFFAYTICGAMGLPWQTALGAVFISGVVFIILTVTKVLQRIIDSIPDVLKTSIGVGIGLFIAFIG
LKNSQIIVANQSTFVGLGNIKDPGVILTFFGLIFTAALFSRRVKGSLLIGMFTTTIVGMFIGITKIPHSIGDIFNLVPPI
PVDTFGKLDIMGAVKYGLVSIVFSITIVDMFDNIGTLIGVSKKAGLVKEDGSIEGLDKALVTGSVAAATGALLGTCTVTS
YVESATGVAEGGRTGLTAVTTGILFLVALFFAPLFMLVPPQATAPVLIIVGVLMLGEVTSINFNDFTEALPGFITILLMP
LTFSIAQGLAMGFISYTLIKVLTGKQKEIKPIMYILTIAFVIHFII

Specific function: Unknown

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082309, Length=440, Percent_Identity=42.2727272727273, Blast_Score=352, Evalue=3e-98,
Organism=Escherichia coli, GI1790150, Length=445, Percent_Identity=41.3483146067416, Blast_Score=342, Evalue=3e-95,
Organism=Escherichia coli, GI1790499, Length=439, Percent_Identity=33.4851936218679, Blast_Score=236, Evalue=2e-63,
Organism=Escherichia coli, GI48994909, Length=446, Percent_Identity=32.9596412556054, Blast_Score=223, Evalue=2e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 47014; Mature: 47014

Theoretical pI: Translated: 8.30; Mature: 8.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEIKQKDCNNNSILEKFFKLTEKGTDVKTEILAGATTFIATAYILAVIPSMLCTTGMPQ
CCEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
TSTVAAVVLTTAFATIFMGMFANLPVVVAPGLGLSAFFAYTICGAMGLPWQTALGAVFIS
HHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
GVVFIILTVTKVLQRIIDSIPDVLKTSIGVGIGLFIAFIGLKNSQIIVANQSTFVGLGNI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEECCCC
KDPGVILTFFGLIFTAALFSRRVKGSLLIGMFTTTIVGMFIGITKIPHSIGDIFNLVPPI
CCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCC
PVDTFGKLDIMGAVKYGLVSIVFSITIVDMFDNIGTLIGVSKKAGLVKEDGSIEGLDKAL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCHHHHHHH
VTGSVAAATGALLGTCTVTSYVESATGVAEGGRTGLTAVTTGILFLVALFFAPLFMLVPP
HHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
QATAPVLIIVGVLMLGEVTSINFNDFTEALPGFITILLMPLTFSIAQGLAMGFISYTLIK
CCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLTGKQKEIKPIMYILTIAFVIHFII
HHCCCCHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MIEIKQKDCNNNSILEKFFKLTEKGTDVKTEILAGATTFIATAYILAVIPSMLCTTGMPQ
CCEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
TSTVAAVVLTTAFATIFMGMFANLPVVVAPGLGLSAFFAYTICGAMGLPWQTALGAVFIS
HHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
GVVFIILTVTKVLQRIIDSIPDVLKTSIGVGIGLFIAFIGLKNSQIIVANQSTFVGLGNI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEECCCC
KDPGVILTFFGLIFTAALFSRRVKGSLLIGMFTTTIVGMFIGITKIPHSIGDIFNLVPPI
CCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCC
PVDTFGKLDIMGAVKYGLVSIVFSITIVDMFDNIGTLIGVSKKAGLVKEDGSIEGLDKAL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCHHHHHHH
VTGSVAAATGALLGTCTVTSYVESATGVAEGGRTGLTAVTTGILFLVALFFAPLFMLVPP
HHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
QATAPVLIIVGVLMLGEVTSINFNDFTEALPGFITILLMPLTFSIAQGLAMGFISYTLIK
CCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLTGKQKEIKPIMYILTIAFVIHFII
HHCCCCHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]