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The map label for this gene is xylB [H]

Identifier: 187935024

GI number: 187935024

Start: 3505141

End: 3506613

Strand: Reverse

Name: xylB [H]

Synonym: CLL_A3333

Alternate gene names: 187935024

Gene position: 3506613-3505141 (Counterclockwise)

Preceding gene: 187932577

Following gene: 187934270

Centisome position: 92.27

GC content: 34.96

Gene sequence:

>1473_bases
ATGTTATATATTGGAGTTGATCTTGGTACATCAGCTGTGAAATTATTATTAATGGATGAAAAAGGGAAAATACATAAGAT
TGTTTCTAAGAAATATCAGTTGTATTTCCCACATACAGGTTGGTCAGAGCAGAAACCAGAGGATTGGTATGTACAGACTT
TGGAGGGAATTAAAGAGTTAATTTTGAATTATAAAAAGGAAGAAATTGCTGGTATCAGTTTTGGAGGGCAAATGCATGGT
TTAGTTATTTTAGATGTGCATGATAAGGTGATTCGTCCAGCAATTTTATGGAATGACGGAAGGAGTCAAAGAGAGACAGA
ATATTTGAATAAAGCCATAGGAAAGGAGAAACTTTCTGAATATACGGCCAATATTGCATTTGCAGGATTTACTGCTCCGA
AAATTCTTTGGATGAAGAAACATGAGCCAAAAAATTTTGAACGAATATCAAAAATTATGCTTCCAAAAGACTATCTAGCA
TATCGCCTAAGTGGCGTTCATTGTACAGATTATTCAGATGCTTCTGGAATGTTATTGCTTGATGTTAAGAATAAGTGTTG
GTCAAAAGAAATGATGAAAATATGTGGTGTGACAGAAAATCAGTTGCCTAAATTATATGAGAGTTATGAGGTTGTGGGCC
GATTAAAACATAATATTGCAGAAGAGTTGGGCATTTCATCAAATGTAAAGATTATTGCAGGAGCTGGTGATAATGCAGCA
GCAGCTGTTGGAACTGGAACAGTAGGGGATGGCATGTGTAATGTTTCATTAGGAACTTCAGGAACAATTTTTATTTCTAG
TAAAACTTTTAGTGTGGATGATAATAATGCACTACACTCATTTGTTAATGCTGATGGATATTATCATTTAATGGGATGTA
TGTTGAGTGCTGCTTCATGTAATAAATGGTGGATGGATGAAATTCTTAATAATAAGGAATATGAAGAAGAACAGAAAAGA
ATTTTAAAACTTGGTGAAAATAAGGTATTTTATTTACCATATCTGATGGGAGAGCGTTCACCACATAATGATCCAAATGC
AAGGGCAACTTTTGTTGGAATGACAATGGATACCAATAGGGATGAAATGACACAAGCAGTATTGGAAGGCGTTGCATTTG
GGTTACGAGATTCGTTGGAAGTAGCAAGAAGTCTTGGTATTAAAATTGAAAGTACGAAAATTTGTGGTGGTGGAGCAAAA
AGTACACTATGGAAAAAGATAATTGCAAATGTGCTTAATTTGACAGTTGATGTGGTCAAAAGTGAGGAGGGTCCAGGTTA
TGGTGGCGCTATTCTTGCTGCAGTTGGATGTGGTGAATTTTCTTCAGTAGAAGAAGCAACAGGTAAACTGGTGAAGATAG
TTAATACTATAAGACCTGAATCAATATTGGTAAAAAAATATGATGAACAATATCAGAAATTCCGTCAGATTTATCCTGCC
ATGAAAGAACTGTTTAAGTCACTAGCAGAATAA

Upstream 100 bases:

>100_bases
TGAAAGGTAAATATATTTGTGGTTATAAATAGAATTATAATATAAATTAAAAAAATATAAACTTACTAAATCCTTGTTTT
TTTATTTTGGGAGGTATTAT

Downstream 100 bases:

>100_bases
GGTAGAAAAACTAATAAAATAAAGAAAAAAACTTATGAATAAACTTGAACTTCAGAAAAATGCTGATAAAGTTCACAAAG
TAATTGTATCTTCGTTACAC

Product: xylulokinase

Products: NA

Alternate protein names: Xylulokinase [H]

Number of amino acids: Translated: 490; Mature: 490

Protein sequence:

>490_residues
MLYIGVDLGTSAVKLLLMDEKGKIHKIVSKKYQLYFPHTGWSEQKPEDWYVQTLEGIKELILNYKKEEIAGISFGGQMHG
LVILDVHDKVIRPAILWNDGRSQRETEYLNKAIGKEKLSEYTANIAFAGFTAPKILWMKKHEPKNFERISKIMLPKDYLA
YRLSGVHCTDYSDASGMLLLDVKNKCWSKEMMKICGVTENQLPKLYESYEVVGRLKHNIAEELGISSNVKIIAGAGDNAA
AAVGTGTVGDGMCNVSLGTSGTIFISSKTFSVDDNNALHSFVNADGYYHLMGCMLSAASCNKWWMDEILNNKEYEEEQKR
ILKLGENKVFYLPYLMGERSPHNDPNARATFVGMTMDTNRDEMTQAVLEGVAFGLRDSLEVARSLGIKIESTKICGGGAK
STLWKKIIANVLNLTVDVVKSEEGPGYGGAILAAVGCGEFSSVEEATGKLVKIVNTIRPESILVKKYDEQYQKFRQIYPA
MKELFKSLAE

Sequences:

>Translated_490_residues
MLYIGVDLGTSAVKLLLMDEKGKIHKIVSKKYQLYFPHTGWSEQKPEDWYVQTLEGIKELILNYKKEEIAGISFGGQMHG
LVILDVHDKVIRPAILWNDGRSQRETEYLNKAIGKEKLSEYTANIAFAGFTAPKILWMKKHEPKNFERISKIMLPKDYLA
YRLSGVHCTDYSDASGMLLLDVKNKCWSKEMMKICGVTENQLPKLYESYEVVGRLKHNIAEELGISSNVKIIAGAGDNAA
AAVGTGTVGDGMCNVSLGTSGTIFISSKTFSVDDNNALHSFVNADGYYHLMGCMLSAASCNKWWMDEILNNKEYEEEQKR
ILKLGENKVFYLPYLMGERSPHNDPNARATFVGMTMDTNRDEMTQAVLEGVAFGLRDSLEVARSLGIKIESTKICGGGAK
STLWKKIIANVLNLTVDVVKSEEGPGYGGAILAAVGCGEFSSVEEATGKLVKIVNTIRPESILVKKYDEQYQKFRQIYPA
MKELFKSLAE
>Mature_490_residues
MLYIGVDLGTSAVKLLLMDEKGKIHKIVSKKYQLYFPHTGWSEQKPEDWYVQTLEGIKELILNYKKEEIAGISFGGQMHG
LVILDVHDKVIRPAILWNDGRSQRETEYLNKAIGKEKLSEYTANIAFAGFTAPKILWMKKHEPKNFERISKIMLPKDYLA
YRLSGVHCTDYSDASGMLLLDVKNKCWSKEMMKICGVTENQLPKLYESYEVVGRLKHNIAEELGISSNVKIIAGAGDNAA
AAVGTGTVGDGMCNVSLGTSGTIFISSKTFSVDDNNALHSFVNADGYYHLMGCMLSAASCNKWWMDEILNNKEYEEEQKR
ILKLGENKVFYLPYLMGERSPHNDPNARATFVGMTMDTNRDEMTQAVLEGVAFGLRDSLEVARSLGIKIESTKICGGGAK
STLWKKIIANVLNLTVDVVKSEEGPGYGGAILAAVGCGEFSSVEEATGKLVKIVNTIRPESILVKKYDEQYQKFRQIYPA
MKELFKSLAE

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI42794763, Length=440, Percent_Identity=25.9090909090909, Blast_Score=129, Evalue=7e-30,
Organism=Homo sapiens, GI189409120, Length=440, Percent_Identity=25.9090909090909, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI4504007, Length=440, Percent_Identity=25.9090909090909, Blast_Score=126, Evalue=5e-29,
Organism=Homo sapiens, GI41393575, Length=436, Percent_Identity=25.9174311926606, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI164663828, Length=549, Percent_Identity=21.8579234972678, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI88196792, Length=482, Percent_Identity=20.954356846473, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI18860918, Length=488, Percent_Identity=24.3852459016393, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI164663830, Length=157, Percent_Identity=28.0254777070064, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1789987, Length=487, Percent_Identity=37.9876796714579, Blast_Score=339, Evalue=3e-94,
Organism=Escherichia coli, GI1790005, Length=498, Percent_Identity=24.8995983935743, Blast_Score=159, Evalue=4e-40,
Organism=Escherichia coli, GI1790361, Length=471, Percent_Identity=25.2653927813163, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1789168, Length=466, Percent_Identity=23.6051502145923, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1787789, Length=515, Percent_Identity=23.3009708737864, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1790338, Length=433, Percent_Identity=21.0161662817552, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17535599, Length=439, Percent_Identity=25.2847380410023, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17554530, Length=482, Percent_Identity=19.9170124481328, Blast_Score=83, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6321633, Length=362, Percent_Identity=23.4806629834254, Blast_Score=74, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24657106, Length=550, Percent_Identity=22.9090909090909, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24657102, Length=550, Percent_Identity=22.9090909090909, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI17864214, Length=468, Percent_Identity=23.9316239316239, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24654573, Length=396, Percent_Identity=23.989898989899, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24655555, Length=426, Percent_Identity=21.5962441314554, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24655560, Length=426, Percent_Identity=21.5962441314554, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24655570, Length=426, Percent_Identity=21.5962441314554, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24655574, Length=426, Percent_Identity=21.5962441314554, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24655565, Length=426, Percent_Identity=21.5962441314554, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI21356607, Length=303, Percent_Identity=24.4224422442244, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI19920476, Length=328, Percent_Identity=23.780487804878, Blast_Score=85, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.17 [H]

Molecular weight: Translated: 54589; Mature: 54589

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: PS00933 FGGY_KINASES_1 ; PS00445 FGGY_KINASES_2 ; PS00107 PROTEIN_KINASE_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYIGVDLGTSAVKLLLMDEKGKIHKIVSKKYQLYFPHTGWSEQKPEDWYVQTLEGIKEL
CEEEEEECCCCCEEEEEECCCCHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHH
ILNYKKEEIAGISFGGQMHGLVILDVHDKVIRPAILWNDGRSQRETEYLNKAIGKEKLSE
HHCCCHHHHCCEECCCCCCCEEEEECCHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHHH
YTANIAFAGFTAPKILWMKKHEPKNFERISKIMLPKDYLAYRLSGVHCTDYSDASGMLLL
HHHCEEEECCCCCEEEEEECCCCCCHHHHHHHHCCHHHHHHHCCCEEECCCCCCCCEEEE
DVKNKCWSKEMMKICGVTENQLPKLYESYEVVGRLKHNIAEELGISSNVKIIAGAGDNAA
ECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCC
AAVGTGTVGDGMCNVSLGTSGTIFISSKTFSVDDNNALHSFVNADGYYHLMGCMLSAASC
EEECCCCCCCCEEEEEECCCEEEEEECEEEECCCCCHHHHHHCCCCHHHHHHHHHHHCCC
NKWWMDEILNNKEYEEEQKRILKLGENKVFYLPYLMGERSPHNDPNARATFVGMTMDTNR
CHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEHHHCCCCCCCCCCCEEEEEEEEECCCH
DEMTQAVLEGVAFGLRDSLEVARSLGIKIESTKICGGGAKSTLWKKIIANVLNLTVDVVK
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHEEEE
SEEGPGYGGAILAAVGCGEFSSVEEATGKLVKIVNTIRPESILVKKYDEQYQKFRQIYPA
CCCCCCCCCHHEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
MKELFKSLAE
HHHHHHHHCC
>Mature Secondary Structure
MLYIGVDLGTSAVKLLLMDEKGKIHKIVSKKYQLYFPHTGWSEQKPEDWYVQTLEGIKEL
CEEEEEECCCCCEEEEEECCCCHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHH
ILNYKKEEIAGISFGGQMHGLVILDVHDKVIRPAILWNDGRSQRETEYLNKAIGKEKLSE
HHCCCHHHHCCEECCCCCCCEEEEECCHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHHH
YTANIAFAGFTAPKILWMKKHEPKNFERISKIMLPKDYLAYRLSGVHCTDYSDASGMLLL
HHHCEEEECCCCCEEEEEECCCCCCHHHHHHHHCCHHHHHHHCCCEEECCCCCCCCEEEE
DVKNKCWSKEMMKICGVTENQLPKLYESYEVVGRLKHNIAEELGISSNVKIIAGAGDNAA
ECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCC
AAVGTGTVGDGMCNVSLGTSGTIFISSKTFSVDDNNALHSFVNADGYYHLMGCMLSAASC
EEECCCCCCCCEEEEEECCCEEEEEECEEEECCCCCHHHHHHCCCCHHHHHHHHHHHCCC
NKWWMDEILNNKEYEEEQKRILKLGENKVFYLPYLMGERSPHNDPNARATFVGMTMDTNR
CHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEHHHCCCCCCCCCCCEEEEEEEEECCCH
DEMTQAVLEGVAFGLRDSLEVARSLGIKIESTKICGGGAKSTLWKKIIANVLNLTVDVVK
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHEEEE
SEEGPGYGGAILAAVGCGEFSSVEEATGKLVKIVNTIRPESILVKKYDEQYQKFRQIYPA
CCCCCCCCCHHEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
MKELFKSLAE
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 2994009 [H]