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The map label for this gene is yeeO [H]

Identifier: 187934418

GI number: 187934418

Start: 2625718

End: 2627079

Strand: Reverse

Name: yeeO [H]

Synonym: CLL_A2520

Alternate gene names: 187934418

Gene position: 2627079-2625718 (Counterclockwise)

Preceding gene: 187932830

Following gene: 187933641

Centisome position: 69.13

GC content: 30.25

Gene sequence:

>1362_bases
ATGTTTATAAGAAAAAATGTTTTGAAATTAGCAATACCAATAATAATAGAGCAAACATTTGTTATGCTTTTGGGTGTATG
CAATACAATGATGGCAGGGCATATAGGAGAAGAAGCTGTTTCTGCAATTGGAATGGTAGATTCAATAAATAATATGTTTA
TATCTTTTTTCGCGGCCTTATCTGTTGGAGCTACTGTAGTTGTTGCGCAACATATTGGAAAAGAGAATCATAAAAAAGCA
AACGAAACAGCTAGACAAGCTTTAGTATCTGGATGCTGTTTAGCTGCTTTAATAAGTATTTTAATGTGGATTTTGCGTGT
TCCAATGATTAACTCTTTGTATGGTACTGCGGAAGAGTTAGTAAAATCAAATGCAAAAATATATTTAGAACTTACACTTA
TTACTTATCCTTTTATTGCAGTGCAACAAATTGCAAATGGAGTATTAAGAGGATGTGGAGATACAAAAACACCAATGTAT
ATTACAATGTTTATGAATATTATTAATATAATTTTAGGATATATATTAATTTATGGAATAAAAGATGTTAATTTATTAGG
ATATGTTTTAAATACAACATCATATGGAATAGATGGTGCAGCAATATCAATTGCAATTGCAAGATTGGTTGGAACAATTC
TTATAGGAATTGTTTTATTTAGAGGAAGTAGAGTTATAAGAATGAGAAAGATTTTCCCATTTAAATTTGATTTAGAAACA
CAAAAGAGTATATTTAATATAGGAATACCAGCAGGTGTTGAGCAAGTACTTTTTAATGCAGGAAAATTAATTGTTCAAAT
ATTTATAGTAACTATGGGAACCGCATCAATAGCAGCAAATGCAATAGGTTCATCAATAGCAACTATTGTTGCAGTTCCAG
GAAATGCACTATGTTTAGCTGCAACAACTTTAGTAGGTCAATATGTAGGAAGAGATGATACAAAAGGTGCTAAAAGTACA
CTTGTGTATTTAACTAAATTTGGAACAGTATGTTTGGTAGCAATAGGTTTAATATTTATTCCTATTTCAGAATGGGTATC
TTCTTTTTATACAGATAGTATAGAGGTAATAAAACTTTCATCTGCATTAATTAAAAGTAATAGCGTGGCTTTAATAGTAT
GGCCTATTTCTTTTATATTATCATCAGGACTAAAGGGTGCTGGAGATACAAGGTATACTATGCTAACAGCTTTTGTAGGA
ATGTGGATTTTTAGAATATTTACAGGCTATATTTTAGGATTAGTATTTGGACTTGGTGTTTTAGGGATTTGGATTGGAAT
GTATACAGATTGGCTGATTAGAGGAATAATGTATTGTTTTAGGCTTAAAGGTGAAAAGTGGCTTAAACATAAAGTTGTAT
AA

Upstream 100 bases:

>100_bases
AGGAGTAATATGATATGATTGTGTTAAAGCAACCATAAAAACTAGTAAATTATACTGAAGACGAATAGTATAGTTATTGG
AAGGGAAAGAGGGCTATAGT

Downstream 100 bases:

>100_bases
TAAATTCAAATAATAGTTTTAAAATTTAATAAAGGTATCAAATATAGTAAAGAGATAATTTATATAAACAGTGTACAATG
TTTTAAGTGAAATTTTTAAG

Product: mate efflux family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 453

Protein sequence:

>453_residues
MFIRKNVLKLAIPIIIEQTFVMLLGVCNTMMAGHIGEEAVSAIGMVDSINNMFISFFAALSVGATVVVAQHIGKENHKKA
NETARQALVSGCCLAALISILMWILRVPMINSLYGTAEELVKSNAKIYLELTLITYPFIAVQQIANGVLRGCGDTKTPMY
ITMFMNIINIILGYILIYGIKDVNLLGYVLNTTSYGIDGAAISIAIARLVGTILIGIVLFRGSRVIRMRKIFPFKFDLET
QKSIFNIGIPAGVEQVLFNAGKLIVQIFIVTMGTASIAANAIGSSIATIVAVPGNALCLAATTLVGQYVGRDDTKGAKST
LVYLTKFGTVCLVAIGLIFIPISEWVSSFYTDSIEVIKLSSALIKSNSVALIVWPISFILSSGLKGAGDTRYTMLTAFVG
MWIFRIFTGYILGLVFGLGVLGIWIGMYTDWLIRGIMYCFRLKGEKWLKHKVV

Sequences:

>Translated_453_residues
MFIRKNVLKLAIPIIIEQTFVMLLGVCNTMMAGHIGEEAVSAIGMVDSINNMFISFFAALSVGATVVVAQHIGKENHKKA
NETARQALVSGCCLAALISILMWILRVPMINSLYGTAEELVKSNAKIYLELTLITYPFIAVQQIANGVLRGCGDTKTPMY
ITMFMNIINIILGYILIYGIKDVNLLGYVLNTTSYGIDGAAISIAIARLVGTILIGIVLFRGSRVIRMRKIFPFKFDLET
QKSIFNIGIPAGVEQVLFNAGKLIVQIFIVTMGTASIAANAIGSSIATIVAVPGNALCLAATTLVGQYVGRDDTKGAKST
LVYLTKFGTVCLVAIGLIFIPISEWVSSFYTDSIEVIKLSSALIKSNSVALIVWPISFILSSGLKGAGDTRYTMLTAFVG
MWIFRIFTGYILGLVFGLGVLGIWIGMYTDWLIRGIMYCFRLKGEKWLKHKVV
>Mature_453_residues
MFIRKNVLKLAIPIIIEQTFVMLLGVCNTMMAGHIGEEAVSAIGMVDSINNMFISFFAALSVGATVVVAQHIGKENHKKA
NETARQALVSGCCLAALISILMWILRVPMINSLYGTAEELVKSNAKIYLELTLITYPFIAVQQIANGVLRGCGDTKTPMY
ITMFMNIINIILGYILIYGIKDVNLLGYVLNTTSYGIDGAAISIAIARLVGTILIGIVLFRGSRVIRMRKIFPFKFDLET
QKSIFNIGIPAGVEQVLFNAGKLIVQIFIVTMGTASIAANAIGSSIATIVAVPGNALCLAATTLVGQYVGRDDTKGAKST
LVYLTKFGTVCLVAIGLIFIPISEWVSSFYTDSIEVIKLSSALIKSNSVALIVWPISFILSSGLKGAGDTRYTMLTAFVG
MWIFRIFTGYILGLVFGLGVLGIWIGMYTDWLIRGIMYCFRLKGEKWLKHKVV

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=448, Percent_Identity=36.6071428571429, Blast_Score=287, Evalue=8e-79,
Organism=Escherichia coli, GI48994890, Length=466, Percent_Identity=26.1802575107296, Blast_Score=94, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 49282; Mature: 49282

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFIRKNVLKLAIPIIIEQTFVMLLGVCNTMMAGHIGEEAVSAIGMVDSINNMFISFFAAL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SVGATVVVAQHIGKENHKKANETARQALVSGCCLAALISILMWILRVPMINSLYGTAEEL
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
VKSNAKIYLELTLITYPFIAVQQIANGVLRGCGDTKTPMYITMFMNIINIILGYILIYGI
HHCCCEEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
KDVNLLGYVLNTTSYGIDGAAISIAIARLVGTILIGIVLFRGSRVIRMRKIFPFKFDLET
CCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHCCCEEECCCH
QKSIFNIGIPAGVEQVLFNAGKLIVQIFIVTMGTASIAANAIGSSIATIVAVPGNALCLA
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHEEEECCCCHHHHH
ATTLVGQYVGRDDTKGAKSTLVYLTKFGTVCLVAIGLIFIPISEWVSSFYTDSIEVIKLS
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
SALIKSNSVALIVWPISFILSSGLKGAGDTRYTMLTAFVGMWIFRIFTGYILGLVFGLGV
HHHHCCCCEEEEEEEHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGIWIGMYTDWLIRGIMYCFRLKGEKWLKHKVV
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCC
>Mature Secondary Structure
MFIRKNVLKLAIPIIIEQTFVMLLGVCNTMMAGHIGEEAVSAIGMVDSINNMFISFFAAL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SVGATVVVAQHIGKENHKKANETARQALVSGCCLAALISILMWILRVPMINSLYGTAEEL
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
VKSNAKIYLELTLITYPFIAVQQIANGVLRGCGDTKTPMYITMFMNIINIILGYILIYGI
HHCCCEEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
KDVNLLGYVLNTTSYGIDGAAISIAIARLVGTILIGIVLFRGSRVIRMRKIFPFKFDLET
CCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHCCCEEECCCH
QKSIFNIGIPAGVEQVLFNAGKLIVQIFIVTMGTASIAANAIGSSIATIVAVPGNALCLA
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHEEEECCCCHHHHH
ATTLVGQYVGRDDTKGAKSTLVYLTKFGTVCLVAIGLIFIPISEWVSSFYTDSIEVIKLS
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
SALIKSNSVALIVWPISFILSSGLKGAGDTRYTMLTAFVGMWIFRIFTGYILGLVFGLGV
HHHHCCCCEEEEEEEHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGIWIGMYTDWLIRGIMYCFRLKGEKWLKHKVV
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]