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The map label for this gene is tlpB [H]

Identifier: 187934202

GI number: 187934202

Start: 3344349

End: 3346403

Strand: Reverse

Name: tlpB [H]

Synonym: CLL_A3212

Alternate gene names: 187934202

Gene position: 3346403-3344349 (Counterclockwise)

Preceding gene: 187935105

Following gene: 187934034

Centisome position: 88.06

GC content: 27.83

Gene sequence:

>2055_bases
ATGAGATTTAAGAAAATAAGTACGAGAATGCTTACAATTCTACTATTTGTAACTATTTTATCAATGGTTTTGCTATCAGG
TATAAGTTATGAAAGTAGCAAGGGTATTATAGACAGACAAGTAGAAGAAAACATGCAAGCAGAATTAAGTTCTACAGTAA
ATGCAATAAATCTTAAGATGCAAGAAATTTCATCAATGTCTAGTCAACTTGCATTGAATGTTGGATCAACTTATAAAACC
ACATATTTATTACAATATGAAGAAATGATTGGAAAAACAATATTTAAAAGTGATCTAGTACTTGGTGCTGGAATTTGGTT
TGAACCATACGTTTATGATGCAAGTAAAGAATATGTTGGGCCGTATATTCATAAAAATGATGATAAGGCATTAGTTACAT
ATGATTATAGCAATGCTGAATATAATTATTTTAATTATGATTGGTATAAGAATGCTAAGAATAATAATAAAGAAACTGTA
TTTAGTGATCTGTACTATGATGAAACATTAAATACTATAATGAGCACTTGCGCTACACCTATATATGATTCAAATGATAA
TTTCATTGGTGTAATTAGTGTTGATATGGAAATTCCATCAATTCAGGATTTGATAAATAATTTCAAGATTGGTGAAAATG
GCAAGGCTTTATTGATAAATAATGACGGGAAATACATAACTAACAGTGATGATAAAAAAATAATGAAAACTAAAATTAAT
GAAGATGAGAATAAATCACTTTCACAATTCGGAAATGTTTTATTAAATAATACTAATGGTAAAAGTGATTTTTCTATTGA
TAATACAGAGTATGAAACTTATTATACTACAGTGGAGCCGTTTGGATGGAAGCTATTTATACAAATACCGATGTCAGAAT
TGAACAAACCTATAAATGAATTAATGTCTAAACTTATAGTGGTAGGAATTTTAGCTATAATATTAACTACATTAGCAATA
ATATGGCAAGTTCGATACTTAACTAAAACTATAAAAAAAGTTAATAATTTAGCATCAAGTTTATCCAATGGAGATTTTTC
TATAAATGAGCTTGAAGTAACATCTGAGGATGAATTAGGACAAATGAGTAATTCATTAAATAAAATGCTATCAGAAAATA
AGAACATGATACAAGAAATATCTGATGATGCAAACAAAGTAAATAGTATAACAGAGAGTTTAAATAAATCAACTGAATCT
CTAGTAGAAAATTATAAAGTGATTAAAGACTCAGTTAAAAACATAAGTGAATCTATGCTTAATTCTAGTGCTACTACTGA
AGAAGTTAATGCTTCTGTAGAAGAAGTTAACTCTTCAATAAGTCTATTGTCACAGGAAACAATTAAAAGTCATGATATGG
CAAAAGACATAAAGGTAAGAGCATACAATATAGAAAAAATGAGTAATGATTCTTATAATAAAGCAACTAGTTTATCAGAA
GTTCATGAAACAAATCTAAAACAAAGCATTGAAAATGCTAAAATAGTTGAAAATATAGGGGCTATGGCTAAAGCTATTTC
TGATATAGCAGAACAAGTTAATTTATTATCACTTAATGCTTCAATAGAAGCTGCACGTGCTGGTGAACAAGGAAAGGGAT
TTGCAGTTGTTGCTTCTGAAATAGGTAATCTTGCAGCACAAACATCAGACACAGTAAAAGAAATTATTGAGACTATAAGT
AAAGTTCAAGAAGCGTTTAATAAATTAACTAATGATTCTACGCAGATGTTATTATTTATTAAAGATACTGTAACTCCGGA
TTATAAAGAATTTGTTGGAATAGCTAATCAATATGATAAGGATGCAAATGCTATTGAAGATATATCTATAAAAATATCTG
AGATGACAAATAACATTGAATACATTACACATGAAGTTGGAGATGCAATACAAAATATTGCAGAAGCTTCTCAAGATACT
GCATCTAATAGTGGAGAGATTGTATGTAGTATAGAATTAGTTTCACAATTAGTTGAGCAAATATCTACTATTGTGGAAAA
TGAAATTGAGGTTTCAGATAATCTTAATTCTATGGTTAAAAATTTTACTTTATAA

Upstream 100 bases:

>100_bases
AAAGGTTTTTTATGCTTTTTATCCTTAATATTAAAATGAGTATTGTAACTAAAATTAATAACCTTATAATTTATTTATTA
ATAAAAAGGGGGAGTTTTTA

Downstream 100 bases:

>100_bases
AAGATTGTTATTAACTATATAATTAGAAAGATACAAAGGAGTTATATATTGTAATTACGTTTAGTAGAAATTTGATATAA
AATATAAAAAAATCAGTTAT

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 684; Mature: 684

Protein sequence:

>684_residues
MRFKKISTRMLTILLFVTILSMVLLSGISYESSKGIIDRQVEENMQAELSSTVNAINLKMQEISSMSSQLALNVGSTYKT
TYLLQYEEMIGKTIFKSDLVLGAGIWFEPYVYDASKEYVGPYIHKNDDKALVTYDYSNAEYNYFNYDWYKNAKNNNKETV
FSDLYYDETLNTIMSTCATPIYDSNDNFIGVISVDMEIPSIQDLINNFKIGENGKALLINNDGKYITNSDDKKIMKTKIN
EDENKSLSQFGNVLLNNTNGKSDFSIDNTEYETYYTTVEPFGWKLFIQIPMSELNKPINELMSKLIVVGILAIILTTLAI
IWQVRYLTKTIKKVNNLASSLSNGDFSINELEVTSEDELGQMSNSLNKMLSENKNMIQEISDDANKVNSITESLNKSTES
LVENYKVIKDSVKNISESMLNSSATTEEVNASVEEVNSSISLLSQETIKSHDMAKDIKVRAYNIEKMSNDSYNKATSLSE
VHETNLKQSIENAKIVENIGAMAKAISDIAEQVNLLSLNASIEAARAGEQGKGFAVVASEIGNLAAQTSDTVKEIIETIS
KVQEAFNKLTNDSTQMLLFIKDTVTPDYKEFVGIANQYDKDANAIEDISIKISEMTNNIEYITHEVGDAIQNIAEASQDT
ASNSGEIVCSIELVSQLVEQISTIVENEIEVSDNLNSMVKNFTL

Sequences:

>Translated_684_residues
MRFKKISTRMLTILLFVTILSMVLLSGISYESSKGIIDRQVEENMQAELSSTVNAINLKMQEISSMSSQLALNVGSTYKT
TYLLQYEEMIGKTIFKSDLVLGAGIWFEPYVYDASKEYVGPYIHKNDDKALVTYDYSNAEYNYFNYDWYKNAKNNNKETV
FSDLYYDETLNTIMSTCATPIYDSNDNFIGVISVDMEIPSIQDLINNFKIGENGKALLINNDGKYITNSDDKKIMKTKIN
EDENKSLSQFGNVLLNNTNGKSDFSIDNTEYETYYTTVEPFGWKLFIQIPMSELNKPINELMSKLIVVGILAIILTTLAI
IWQVRYLTKTIKKVNNLASSLSNGDFSINELEVTSEDELGQMSNSLNKMLSENKNMIQEISDDANKVNSITESLNKSTES
LVENYKVIKDSVKNISESMLNSSATTEEVNASVEEVNSSISLLSQETIKSHDMAKDIKVRAYNIEKMSNDSYNKATSLSE
VHETNLKQSIENAKIVENIGAMAKAISDIAEQVNLLSLNASIEAARAGEQGKGFAVVASEIGNLAAQTSDTVKEIIETIS
KVQEAFNKLTNDSTQMLLFIKDTVTPDYKEFVGIANQYDKDANAIEDISIKISEMTNNIEYITHEVGDAIQNIAEASQDT
ASNSGEIVCSIELVSQLVEQISTIVENEIEVSDNLNSMVKNFTL
>Mature_684_residues
MRFKKISTRMLTILLFVTILSMVLLSGISYESSKGIIDRQVEENMQAELSSTVNAINLKMQEISSMSSQLALNVGSTYKT
TYLLQYEEMIGKTIFKSDLVLGAGIWFEPYVYDASKEYVGPYIHKNDDKALVTYDYSNAEYNYFNYDWYKNAKNNNKETV
FSDLYYDETLNTIMSTCATPIYDSNDNFIGVISVDMEIPSIQDLINNFKIGENGKALLINNDGKYITNSDDKKIMKTKIN
EDENKSLSQFGNVLLNNTNGKSDFSIDNTEYETYYTTVEPFGWKLFIQIPMSELNKPINELMSKLIVVGILAIILTTLAI
IWQVRYLTKTIKKVNNLASSLSNGDFSINELEVTSEDELGQMSNSLNKMLSENKNMIQEISDDANKVNSITESLNKSTES
LVENYKVIKDSVKNISESMLNSSATTEEVNASVEEVNSSISLLSQETIKSHDMAKDIKVRAYNIEKMSNDSYNKATSLSE
VHETNLKQSIENAKIVENIGAMAKAISDIAEQVNLLSLNASIEAARAGEQGKGFAVVASEIGNLAAQTSDTVKEIIETIS
KVQEAFNKLTNDSTQMLLFIKDTVTPDYKEFVGIANQYDKDANAIEDISIKISEMTNNIEYITHEVGDAIQNIAEASQDT
ASNSGEIVCSIELVSQLVEQISTIVENEIEVSDNLNSMVKNFTL

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=317, Percent_Identity=27.4447949526814, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1787690, Length=324, Percent_Identity=26.5432098765432, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1789453, Length=253, Percent_Identity=28.8537549407115, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1788195, Length=242, Percent_Identity=29.3388429752066, Blast_Score=83, Evalue=7e-17,
Organism=Escherichia coli, GI1788194, Length=198, Percent_Identity=31.3131313131313, Blast_Score=82, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 76385; Mature: 76385

Theoretical pI: Translated: 4.26; Mature: 4.26

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFKKISTRMLTILLFVTILSMVLLSGISYESSKGIIDRQVEENMQAELSSTVNAINLKM
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
QEISSMSSQLALNVGSTYKTTYLLQYEEMIGKTIFKSDLVLGAGIWFEPYVYDASKEYVG
HHHHHHHHHHEEECCCCCCEEEEEEHHHHHHHHHHHHCHHEECCCCCCCEEECCCHHHCC
PYIHKNDDKALVTYDYSNAEYNYFNYDWYKNAKNNNKETVFSDLYYDETLNTIMSTCATP
CCEECCCCCEEEEEECCCCEECEECCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
IYDSNDNFIGVISVDMEIPSIQDLINNFKIGENGKALLINNDGKYITNSDDKKIMKTKIN
CCCCCCCEEEEEEECCCCCHHHHHHHCCCCCCCCCEEEEECCCCEEECCCCHHHHHHHCC
EDENKSLSQFGNVLLNNTNGKSDFSIDNTEYETYYTTVEPFGWKLFIQIPMSELNKPINE
CCCCHHHHHHCCEEEECCCCCCCCCCCCCEEEEEEEEECCCCEEEEEECCHHHHCHHHHH
LMSKLIVVGILAIILTTLAIIWQVRYLTKTIKKVNNLASSLSNGDFSINELEVTSEDELG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHH
QMSNSLNKMLSENKNMIQEISDDANKVNSITESLNKSTESLVENYKVIKDSVKNISESML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NSSATTEEVNASVEEVNSSISLLSQETIKSHDMAKDIKVRAYNIEKMSNDSYNKATSLSE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCEEEEEEHHHCCCCCCCHHHHHHH
VHETNLKQSIENAKIVENIGAMAKAISDIAEQVNLLSLNASIEAARAGEQGKGFAVVASE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHCCCCCCCEEEEHHH
IGNLAAQTSDTVKEIIETISKVQEAFNKLTNDSTQMLLFIKDTVTPDYKEFVGIANQYDK
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHCCC
DANAIEDISIKISEMTNNIEYITHEVGDAIQNIAEASQDTASNSGEIVCSIELVSQLVEQ
CCCCHHHHEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHH
ISTIVENEIEVSDNLNSMVKNFTL
HHHHHHCCHHHHCCHHHHHHHCCC
>Mature Secondary Structure
MRFKKISTRMLTILLFVTILSMVLLSGISYESSKGIIDRQVEENMQAELSSTVNAINLKM
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
QEISSMSSQLALNVGSTYKTTYLLQYEEMIGKTIFKSDLVLGAGIWFEPYVYDASKEYVG
HHHHHHHHHHEEECCCCCCEEEEEEHHHHHHHHHHHHCHHEECCCCCCCEEECCCHHHCC
PYIHKNDDKALVTYDYSNAEYNYFNYDWYKNAKNNNKETVFSDLYYDETLNTIMSTCATP
CCEECCCCCEEEEEECCCCEECEECCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
IYDSNDNFIGVISVDMEIPSIQDLINNFKIGENGKALLINNDGKYITNSDDKKIMKTKIN
CCCCCCCEEEEEEECCCCCHHHHHHHCCCCCCCCCEEEEECCCCEEECCCCHHHHHHHCC
EDENKSLSQFGNVLLNNTNGKSDFSIDNTEYETYYTTVEPFGWKLFIQIPMSELNKPINE
CCCCHHHHHHCCEEEECCCCCCCCCCCCCEEEEEEEEECCCCEEEEEECCHHHHCHHHHH
LMSKLIVVGILAIILTTLAIIWQVRYLTKTIKKVNNLASSLSNGDFSINELEVTSEDELG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHH
QMSNSLNKMLSENKNMIQEISDDANKVNSITESLNKSTESLVENYKVIKDSVKNISESML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NSSATTEEVNASVEEVNSSISLLSQETIKSHDMAKDIKVRAYNIEKMSNDSYNKATSLSE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCEEEEEEHHHCCCCCCCHHHHHHH
VHETNLKQSIENAKIVENIGAMAKAISDIAEQVNLLSLNASIEAARAGEQGKGFAVVASE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHCCCCCCCEEEEHHH
IGNLAAQTSDTVKEIIETISKVQEAFNKLTNDSTQMLLFIKDTVTPDYKEFVGIANQYDK
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHCCC
DANAIEDISIKISEMTNNIEYITHEVGDAIQNIAEASQDTASNSGEIVCSIELVSQLVEQ
CCCCHHHHEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHH
ISTIVENEIEVSDNLNSMVKNFTL
HHHHHHCCHHHHCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8188684; 9384377 [H]