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The map label for this gene is yycG [H]

Identifier: 187933521

GI number: 187933521

Start: 1944108

End: 1945871

Strand: Reverse

Name: yycG [H]

Synonym: CLL_A1851

Alternate gene names: 187933521

Gene position: 1945871-1944108 (Counterclockwise)

Preceding gene: 187933765

Following gene: 187933655

Centisome position: 51.2

GC content: 22.85

Gene sequence:

>1764_bases
ATGGGTAAAGAAGAAAATCAGGTATATGTATTTAAAAACTTAAAGGACATGTTAAAATCACAACCTGCAAAAGAAATTGT
AAACAATAAATATATTAATGAGTGTGTTAGAGAGGAATCTGAGAATTTTAAAAATACATTAATAAATTTAAATAGAGAAA
CAAATGCAGAAGGAATTACTTTATTTTTATACGATGAAAAAGAAAACATGTTAAAATTAAAATTTAAGTTAGGAAATGCA
TCAGTGATAGAAGATAATTATACAATAAAATTATGTGAAGAATCTAAGGCAAATTTAATTACCAATAAATATGTTCACAG
AACTATAGATATAAAAGAAACATATTTGTTTAAAAAATATATAGAAAACAATAATATTAATATAAATAAAAACTATGGAT
ATATAAGAATGTATTCAATAAAAGATACAAATAGATTAATAGGTGTTTTAAGTATTTTTTATGATAAAAATATTGATTTG
GATAAGATAAATAACAATGTTATAGATTACGAATGTGAGAAATTAGAATTATTAATTAAAAATAAAATTTTAACCAATAA
ATTAAGAGAAGAACTTATAAAAAGAACATTAAGTGAAAGTAAGCTAAAATCTTTTTTGGAAATTGCAACTGATTTGTGGG
CAATAATGGATTATAAACAACATTTTAAGTGTGTATCTCCAAGTGTTATTGATGTTACAGGATGGAGTAATGAAAAAATA
TCAATAATGAATGTATTTGATATGGTACATCCAGATGATAGAGAAAGAGCAAGAAAATATATAAAATTTATAAAAGATGC
AAAAGGTGAAAATTCTATTGCTAAAGTACTGTGTGCAAATGGTGAATGTAAGATATTTCAATGGAATTGGAGCTGTATTG
AAGAAGGAAAATATGTATTTTTAGCTGCAAAAGATATTACAGAACAAAGAAAATTACAGCAACAAAAAAAAGAACTAGAA
GAAGCCATTATGATTGAAAATTTCAAAAATAAGTTTCTTGCTAATATATCACATGAATTTAAGACACCTTTAAATGTAAT
ACTTTCTACTTTACAGCTTATAGATAAAAATAGCAATGATTTAAAAATTCATGAAATAGATTTAATTAATTACATAGATG
GAATTAAGAGAAATTCTTATAGGCTATTAAGACTTATAAATAATCTAATAGATATAACTAAAATAGATTCAGGACATTAT
AATTTACAACTGCAAAATTATAATGCGGTTGAAATAATTGAAGATATAGTAATGGCAGTAAGAGAATATATAAAAGAAAA
CACTAGAGATATAATTTTTGATACAAGTGAAGAAGAAATAATAACGGCTTTGGATGAAAATAAAATTGAAACTATAATAT
TAAATTTACTTTCTAACGCTATAAAATATACAAATGATGATGGAATAATAGAAGTAAGTATAAAATACAGTAAAGATAGA
AAAAATATACTTATTAGTATAAAAGATAATGGAATAGGAATAGATAGTAATGATATAAATAATATTTTTAAAAGATTTAA
ATATTCTAATAATATACTTAATAGAAGATGTGAGGGTACAGGAGTAGGTTTATCACTTGTAAAATCTTTAGTGGAAATGC
ATGGCGGTAAGATAATTGCTAAAAATAATCAACTTAAAGGAGCAGAGTTCATTTTTTCAATTCCAGTGAAATTAACACGG
GGTGATACTACTAATAATAATAAGATTTTAGAAAGTAGTATAAAAAAATGTAATATAGAATTTTCAGACATATATTTTCT
ATAA

Upstream 100 bases:

>100_bases
TTTTTTATGACAAAACTTGATTCAAGGTTTGAAAAATATAATATAGAATTTTCGGATGTATATTAGAGTGTCATGGTTAC
TATAATAAGGGGATAATATA

Downstream 100 bases:

>100_bases
GAAAACTATTTATTTTACTTATAGAATTTGCTAATTATCTTTTTGTAAACTATATTAAAGTGAAATTATATTAGTAAATT
AAGTATAATATAATTTCACT

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 587; Mature: 586

Protein sequence:

>587_residues
MGKEENQVYVFKNLKDMLKSQPAKEIVNNKYINECVREESENFKNTLINLNRETNAEGITLFLYDEKENMLKLKFKLGNA
SVIEDNYTIKLCEESKANLITNKYVHRTIDIKETYLFKKYIENNNININKNYGYIRMYSIKDTNRLIGVLSIFYDKNIDL
DKINNNVIDYECEKLELLIKNKILTNKLREELIKRTLSESKLKSFLEIATDLWAIMDYKQHFKCVSPSVIDVTGWSNEKI
SIMNVFDMVHPDDRERARKYIKFIKDAKGENSIAKVLCANGECKIFQWNWSCIEEGKYVFLAAKDITEQRKLQQQKKELE
EAIMIENFKNKFLANISHEFKTPLNVILSTLQLIDKNSNDLKIHEIDLINYIDGIKRNSYRLLRLINNLIDITKIDSGHY
NLQLQNYNAVEIIEDIVMAVREYIKENTRDIIFDTSEEEIITALDENKIETIILNLLSNAIKYTNDDGIIEVSIKYSKDR
KNILISIKDNGIGIDSNDINNIFKRFKYSNNILNRRCEGTGVGLSLVKSLVEMHGGKIIAKNNQLKGAEFIFSIPVKLTR
GDTTNNNKILESSIKKCNIEFSDIYFL

Sequences:

>Translated_587_residues
MGKEENQVYVFKNLKDMLKSQPAKEIVNNKYINECVREESENFKNTLINLNRETNAEGITLFLYDEKENMLKLKFKLGNA
SVIEDNYTIKLCEESKANLITNKYVHRTIDIKETYLFKKYIENNNININKNYGYIRMYSIKDTNRLIGVLSIFYDKNIDL
DKINNNVIDYECEKLELLIKNKILTNKLREELIKRTLSESKLKSFLEIATDLWAIMDYKQHFKCVSPSVIDVTGWSNEKI
SIMNVFDMVHPDDRERARKYIKFIKDAKGENSIAKVLCANGECKIFQWNWSCIEEGKYVFLAAKDITEQRKLQQQKKELE
EAIMIENFKNKFLANISHEFKTPLNVILSTLQLIDKNSNDLKIHEIDLINYIDGIKRNSYRLLRLINNLIDITKIDSGHY
NLQLQNYNAVEIIEDIVMAVREYIKENTRDIIFDTSEEEIITALDENKIETIILNLLSNAIKYTNDDGIIEVSIKYSKDR
KNILISIKDNGIGIDSNDINNIFKRFKYSNNILNRRCEGTGVGLSLVKSLVEMHGGKIIAKNNQLKGAEFIFSIPVKLTR
GDTTNNNKILESSIKKCNIEFSDIYFL
>Mature_586_residues
GKEENQVYVFKNLKDMLKSQPAKEIVNNKYINECVREESENFKNTLINLNRETNAEGITLFLYDEKENMLKLKFKLGNAS
VIEDNYTIKLCEESKANLITNKYVHRTIDIKETYLFKKYIENNNININKNYGYIRMYSIKDTNRLIGVLSIFYDKNIDLD
KINNNVIDYECEKLELLIKNKILTNKLREELIKRTLSESKLKSFLEIATDLWAIMDYKQHFKCVSPSVIDVTGWSNEKIS
IMNVFDMVHPDDRERARKYIKFIKDAKGENSIAKVLCANGECKIFQWNWSCIEEGKYVFLAAKDITEQRKLQQQKKELEE
AIMIENFKNKFLANISHEFKTPLNVILSTLQLIDKNSNDLKIHEIDLINYIDGIKRNSYRLLRLINNLIDITKIDSGHYN
LQLQNYNAVEIIEDIVMAVREYIKENTRDIIFDTSEEEIITALDENKIETIILNLLSNAIKYTNDDGIIEVSIKYSKDRK
NILISIKDNGIGIDSNDINNIFKRFKYSNNILNRRCEGTGVGLSLVKSLVEMHGGKIIAKNNQLKGAEFIFSIPVKLTRG
DTTNNNKILESSIKKCNIEFSDIYFL

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=269, Percent_Identity=31.5985130111524, Blast_Score=105, Evalue=8e-24,
Organism=Escherichia coli, GI1786912, Length=231, Percent_Identity=27.2727272727273, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1788713, Length=263, Percent_Identity=28.5171102661597, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI145693157, Length=260, Percent_Identity=26.1538461538462, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI87081816, Length=252, Percent_Identity=28.968253968254, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1788393, Length=268, Percent_Identity=25, Blast_Score=95, Evalue=2e-20,
Organism=Escherichia coli, GI1786600, Length=262, Percent_Identity=22.9007633587786, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1790436, Length=255, Percent_Identity=25.4901960784314, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI48994928, Length=409, Percent_Identity=25.1833740831296, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1790346, Length=276, Percent_Identity=22.463768115942, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1787894, Length=228, Percent_Identity=26.3157894736842, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788549, Length=254, Percent_Identity=24.0157480314961, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1790300, Length=277, Percent_Identity=24.187725631769, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1790551, Length=217, Percent_Identity=22.5806451612903, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1790861, Length=261, Percent_Identity=23.7547892720307, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1788279, Length=242, Percent_Identity=23.9669421487603, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI87082128, Length=236, Percent_Identity=22.8813559322034, Blast_Score=62, Evalue=8e-11,
Organism=Escherichia coli, GI1786783, Length=267, Percent_Identity=22.4719101123595, Blast_Score=62, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 68361; Mature: 68229

Theoretical pI: Translated: 7.69; Mature: 7.69

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKEENQVYVFKNLKDMLKSQPAKEIVNNKYINECVREESENFKNTLINLNRETNAEGIT
CCCCCCEEEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCEEE
LFLYDEKENMLKLKFKLGNASVIEDNYTIKLCEESKANLITNKYVHRTIDIKETYLFKKY
EEEEECCCCEEEEEEEECCCEEEECCCEEEEECCCCCCHHHHHHHHEEECHHHHHHHHHH
IENNNININKNYGYIRMYSIKDTNRLIGVLSIFYDKNIDLDKINNNVIDYECEKLELLIK
HCCCCEEEECCCCEEEEEEECCCHHHHHHHHHHHCCCCCHHHCCCCEECCCHHHHHHHHH
NKILTNKLREELIKRTLSESKLKSFLEIATDLWAIMDYKQHFKCVSPSVIDVTGWSNEKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEECCCCCCE
SIMNVFDMVHPDDRERARKYIKFIKDAKGENSIAKVLCANGECKIFQWNWSCIEEGKYVF
EEEEHHHCCCCCCHHHHHHHHHHHHCCCCCCCEEHEEECCCCEEEEEECCCEECCCCEEE
LAAKDITEQRKLQQQKKELEEAIMIENFKNKFLANISHEFKTPLNVILSTLQLIDKNSND
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHCCCCCC
LKIHEIDLINYIDGIKRNSYRLLRLINNLIDITKIDSGHYNLQLQNYNAVEIIEDIVMAV
EEEEEEEHHHHHHHCCCCHHHHHHHHHHHHHHEEECCCEEEEEECCCCHHHHHHHHHHHH
REYIKENTRDIIFDTSEEEIITALDENKIETIILNLLSNAIKYTNDDGIIEVSIKYSKDR
HHHHHCCCCEEEEECCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCC
KNILISIKDNGIGIDSNDINNIFKRFKYSNNILNRRCEGTGVGLSLVKSLVEMHGGKIIA
CEEEEEEECCCCCCCCCHHHHHHHHHHHCCCHHHCCCCCCCCCHHHHHHHHHHCCCEEEE
KNNQLKGAEFIFSIPVKLTRGDTTNNNKILESSIKKCNIEFSDIYFL
ECCCCCCCEEEEEECEEEECCCCCCCCHHHHHHHHHCCCCHHEEEEC
>Mature Secondary Structure 
GKEENQVYVFKNLKDMLKSQPAKEIVNNKYINECVREESENFKNTLINLNRETNAEGIT
CCCCCEEEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCEEE
LFLYDEKENMLKLKFKLGNASVIEDNYTIKLCEESKANLITNKYVHRTIDIKETYLFKKY
EEEEECCCCEEEEEEEECCCEEEECCCEEEEECCCCCCHHHHHHHHEEECHHHHHHHHHH
IENNNININKNYGYIRMYSIKDTNRLIGVLSIFYDKNIDLDKINNNVIDYECEKLELLIK
HCCCCEEEECCCCEEEEEEECCCHHHHHHHHHHHCCCCCHHHCCCCEECCCHHHHHHHHH
NKILTNKLREELIKRTLSESKLKSFLEIATDLWAIMDYKQHFKCVSPSVIDVTGWSNEKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEECCCCCCE
SIMNVFDMVHPDDRERARKYIKFIKDAKGENSIAKVLCANGECKIFQWNWSCIEEGKYVF
EEEEHHHCCCCCCHHHHHHHHHHHHCCCCCCCEEHEEECCCCEEEEEECCCEECCCCEEE
LAAKDITEQRKLQQQKKELEEAIMIENFKNKFLANISHEFKTPLNVILSTLQLIDKNSND
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHCCCCCC
LKIHEIDLINYIDGIKRNSYRLLRLINNLIDITKIDSGHYNLQLQNYNAVEIIEDIVMAV
EEEEEEEHHHHHHHCCCCHHHHHHHHHHHHHHEEECCCEEEEEECCCCHHHHHHHHHHHH
REYIKENTRDIIFDTSEEEIITALDENKIETIILNLLSNAIKYTNDDGIIEVSIKYSKDR
HHHHHCCCCEEEEECCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCC
KNILISIKDNGIGIDSNDINNIFKRFKYSNNILNRRCEGTGVGLSLVKSLVEMHGGKIIA
CEEEEEEECCCCCCCCCHHHHHHHHHHHCCCHHHCCCCCCCCCHHHHHHHHHHCCCEEEE
KNNQLKGAEFIFSIPVKLTRGDTTNNNKILESSIKKCNIEFSDIYFL
ECCCCCCCEEEEEECEEEECCCCCCCCHHHHHHHHHCCCCHHEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]