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The map label for this gene is cat3 [H]

Identifier: 187933481

GI number: 187933481

Start: 2253143

End: 2253778

Strand: Reverse

Name: cat3 [H]

Synonym: CLL_A2166

Alternate gene names: 187933481

Gene position: 2253778-2253143 (Counterclockwise)

Preceding gene: 187934235

Following gene: 187933958

Centisome position: 59.3

GC content: 25.94

Gene sequence:

>636_bases
ATGAAACTTATAGATATAGAAAATTGGAAGAGAAAAGATCATTATAATTTTTTTAGGCAAGTTGATTACCCTCATTTTAA
TATTTGTGGAAATATTGATATTACAAAGTTTTATAAATATATTAAAGAAAATGAATTGCCATTTTTTATATCGATTTTAT
ACGCTTCTACAAAAACAGCAAATAGCATAAAAGAATTTAAACTTAGAATAAGAGGAGATAAAGTAATTGAACATGAAACT
GTAAATCCCTCTTTTACTATAATTACGGATGAGGAAGTGTTTAGTTTTTGTAGATCAAACTACACAGATAACTTTAATGA
GTTTAAAATTAATACATTAAAGGAAATTGAAAAGGTAAAAAATAATATTAGTATTGAAGATGAACCAGGACAAGATGATT
TATTATATATTACCAGTATTCCATGGGTTTCATTTACTAATATAACTCATCCAATTCAGATGAATCCTGTTGATAGCATA
CCTAGAATAGCATGGGGTAAATATTTTGAAGAAGGTGGTAATATTAAGTTACCAATTTCTGTGGATGTACATCATGCATT
AGTTGATGGGGTACACATTGGACAATATTTTAATATTATTCAAGAAATTTTAGATAATCCTATGAAGTATCTATAA

Upstream 100 bases:

>100_bases
GGAGATATTGGTGGGCGTAATTTATATATGGAGAACAAAGGAATAATTGGCATATATAAAATAAATTAGTGTGTAGTATT
AGAAAGAGAGTGATATTTTA

Downstream 100 bases:

>100_bases
GATATAATTTTAATGGGAATTTTCATATATTAAATGATGCCTAAAATTTGAAAAATATTTCAAATTAAATTGTTTGAAGG
AAGTATGGGAACAGAAAATA

Product: chloramphenicol O-acetyltransferase

Products: NA

Alternate protein names: Chloramphenicol acetyltransferase III; CAT-III [H]

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MKLIDIENWKRKDHYNFFRQVDYPHFNICGNIDITKFYKYIKENELPFFISILYASTKTANSIKEFKLRIRGDKVIEHET
VNPSFTIITDEEVFSFCRSNYTDNFNEFKINTLKEIEKVKNNISIEDEPGQDDLLYITSIPWVSFTNITHPIQMNPVDSI
PRIAWGKYFEEGGNIKLPISVDVHHALVDGVHIGQYFNIIQEILDNPMKYL

Sequences:

>Translated_211_residues
MKLIDIENWKRKDHYNFFRQVDYPHFNICGNIDITKFYKYIKENELPFFISILYASTKTANSIKEFKLRIRGDKVIEHET
VNPSFTIITDEEVFSFCRSNYTDNFNEFKINTLKEIEKVKNNISIEDEPGQDDLLYITSIPWVSFTNITHPIQMNPVDSI
PRIAWGKYFEEGGNIKLPISVDVHHALVDGVHIGQYFNIIQEILDNPMKYL
>Mature_211_residues
MKLIDIENWKRKDHYNFFRQVDYPHFNICGNIDITKFYKYIKENELPFFISILYASTKTANSIKEFKLRIRGDKVIEHET
VNPSFTIITDEEVFSFCRSNYTDNFNEFKINTLKEIEKVKNNISIEDEPGQDDLLYITSIPWVSFTNITHPIQMNPVDSI
PRIAWGKYFEEGGNIKLPISVDVHHALVDGVHIGQYFNIIQEILDNPMKYL

Specific function: This enzyme is an effector of chloramphenicol resistance in bacteria [H]

COG id: COG4845

COG function: function code V; Chloramphenicol O-acetyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chloramphenicol acetyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023213
- InterPro:   IPR018372
- InterPro:   IPR001707
- ProDom:   PD002660 [H]

Pfam domain/function: PF00302 CAT [H]

EC number: =2.3.1.28 [H]

Molecular weight: Translated: 24863; Mature: 24863

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLIDIENWKRKDHYNFFRQVDYPHFNICGNIDITKFYKYIKENELPFFISILYASTKTA
CEEECCCCCCCCHHHHHHHHCCCCCEEEECCCCHHHHHHHHHCCCCCEEEEEEECCCCCH
NSIKEFKLRIRGDKVIEHETVNPSFTIITDEEVFSFCRSNYTDNFNEFKINTLKEIEKVK
HHHHHHHEEECCCEEEEEECCCCCEEEEEHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHH
NNISIEDEPGQDDLLYITSIPWVSFTNITHPIQMNPVDSIPRIAWGKYFEEGGNIKLPIS
HCCCCCCCCCCCCEEEEEECCCEEECCCCCCEECCCCCCCCHHHHHHHHHCCCCEEEEEE
VDVHHALVDGVHIGQYFNIIQEILDNPMKYL
ECHHHHHHCCCHHHHHHHHHHHHHHCHHHCC
>Mature Secondary Structure
MKLIDIENWKRKDHYNFFRQVDYPHFNICGNIDITKFYKYIKENELPFFISILYASTKTA
CEEECCCCCCCCHHHHHHHHCCCCCEEEECCCCHHHHHHHHHCCCCCEEEEEEECCCCCH
NSIKEFKLRIRGDKVIEHETVNPSFTIITDEEVFSFCRSNYTDNFNEFKINTLKEIEKVK
HHHHHHHEEECCCEEEEEECCCCCEEEEEHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHH
NNISIEDEPGQDDLLYITSIPWVSFTNITHPIQMNPVDSIPRIAWGKYFEEGGNIKLPIS
HCCCCCCCCCCCCEEEEEECCCEEECCCCCCEECCCCCCCCHHHHHHHHHCCCCEEEEEE
VDVHHALVDGVHIGQYFNIIQEILDNPMKYL
ECHHHHHHCCCHHHHHHHHHHHHHHCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3048245; 3288984; 2187098 [H]