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The map label for this gene is ftsX [H]

Identifier: 187933240

GI number: 187933240

Start: 3535604

End: 3536494

Strand: Reverse

Name: ftsX [H]

Synonym: CLL_A3352

Alternate gene names: 187933240

Gene position: 3536494-3535604 (Counterclockwise)

Preceding gene: 187934440

Following gene: 187932500

Centisome position: 93.06

GC content: 28.62

Gene sequence:

>891_bases
ATGAGAATTAATACATTTACATATTTTATAAAAGATGCATTTACTAGTTTAAAAAGAAATAGAACTATAAGTTTTGCCTC
AATACTTACAGTACTTATAACCTTCTTTGTTTTAGGAATATTTATATTATTAGCAGGTAATGTAAATCAAGCTATTAGTA
GCGTTCAAGACAAAGTAGATCTTGAAGTGTTCCTTAAAGACGATATAAAACTTATTGATCAAAGAGAAATAGAATTAAAA
TTAAGAGAACTAGAAGGTGTAAAAGACGTTGTATATAAATCAAAAGAAGAAGCATATAAGAAAGTTCAAGACACAACAAG
TGAAAATGAAGGATTATTACAAGGTTATACTTTAGAACATAATCCATTCCCAGCTTCATTTACTGTAAAGTTAGAATCAC
CTGAATATGCAGAAAATATAAGCCAAGCTTTAGATGGATTTACAGGAGTTGAAAAGATAGACAATCAGAAAAAGGTTGTT
GATGGAATCGTAAAACTTGTAAAAGGTATAAATATAGTTGGCGGAGCATTATTTATAGTTTTAGTTGGAGTATCTATTTT
CTTAATAATGAATACAACTAAATTAACAGTTTATTCAAGAAGAAGAGAAGTTGGAATAATGAAGTTTGTAGGAGCCACTG
ATTGGTTTATAAGATGGCCTTTCATAATAGAAGGTATGGTAATTGGGGTTTTAGGATCTACATTATCATGCATAGTGTTA
TTCTTTGCTTATAAAGGAGTATTCAGTTGGATAGCATCAATGATGATGTTTGTCACTCTTGTTCCTCCTATATATATTTT
AAAAGTAGTTTTATTAGAATTTATAATTGGTGGGATTTTAGTTGGTGGAATAGCTAGTGCATCAGCTTTAAGAAAATTCT
TAATAGTATAA

Upstream 100 bases:

>100_bases
GCCACTCATGCAAAGGAAATAGTTGATTATATGAAGAAGAGAGTTATAGCAATTGATAGAGGAGAAATAGTAAGAGACGA
AAAGAGAGGTAAGTACGAAG

Downstream 100 bases:

>100_bases
TTTCTTATAAATAAGAATAAAATTAACTTATAAATAAAAATAATGGACCAAATATTCTTTAGATATTTTTAATTATTAGA
ATAAATAGAGTATTAATACT

Product: cell-division protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MRINTFTYFIKDAFTSLKRNRTISFASILTVLITFFVLGIFILLAGNVNQAISSVQDKVDLEVFLKDDIKLIDQREIELK
LRELEGVKDVVYKSKEEAYKKVQDTTSENEGLLQGYTLEHNPFPASFTVKLESPEYAENISQALDGFTGVEKIDNQKKVV
DGIVKLVKGINIVGGALFIVLVGVSIFLIMNTTKLTVYSRRREVGIMKFVGATDWFIRWPFIIEGMVIGVLGSTLSCIVL
FFAYKGVFSWIASMMMFVTLVPPIYILKVVLLEFIIGGILVGGIASASALRKFLIV

Sequences:

>Translated_296_residues
MRINTFTYFIKDAFTSLKRNRTISFASILTVLITFFVLGIFILLAGNVNQAISSVQDKVDLEVFLKDDIKLIDQREIELK
LRELEGVKDVVYKSKEEAYKKVQDTTSENEGLLQGYTLEHNPFPASFTVKLESPEYAENISQALDGFTGVEKIDNQKKVV
DGIVKLVKGINIVGGALFIVLVGVSIFLIMNTTKLTVYSRRREVGIMKFVGATDWFIRWPFIIEGMVIGVLGSTLSCIVL
FFAYKGVFSWIASMMMFVTLVPPIYILKVVLLEFIIGGILVGGIASASALRKFLIV
>Mature_296_residues
MRINTFTYFIKDAFTSLKRNRTISFASILTVLITFFVLGIFILLAGNVNQAISSVQDKVDLEVFLKDDIKLIDQREIELK
LRELEGVKDVVYKSKEEAYKKVQDTTSENEGLLQGYTLEHNPFPASFTVKLESPEYAENISQALDGFTGVEKIDNQKKVV
DGIVKLVKGINIVGGALFIVLVGVSIFLIMNTTKLTVYSRRREVGIMKFVGATDWFIRWPFIIEGMVIGVLGSTLSCIVL
FFAYKGVFSWIASMMMFVTLVPPIYILKVVLLEFIIGGILVGGIASASALRKFLIV

Specific function: Part of the ABC transporter ftsEX involved in sporulation. May act as an importer, possibly at the top of a hierarchical cascade leading to the correct temporal initiation of sporulation. Acts upstream of the histidine kinases KinA, KinB and KInC, the Rap

COG id: COG2177

COG function: function code D; Cell division protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable). Note=Unlike the E.coli ortholog, localization is not restricted to division septa, nor is it dependent on ftsZ [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789872, Length=241, Percent_Identity=26.9709543568465, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 33092; Mature: 33092

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRINTFTYFIKDAFTSLKRNRTISFASILTVLITFFVLGIFILLAGNVNQAISSVQDKVD
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LEVFLKDDIKLIDQREIELKLRELEGVKDVVYKSKEEAYKKVQDTTSENEGLLQGYTLEH
HHEEEHHHHHHHCCHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHCCCCCCCCEECEEECC
NPFPASFTVKLESPEYAENISQALDGFTGVEKIDNQKKVVDGIVKLVKGINIVGGALFIV
CCCCCEEEEEECCCHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHH
LVGVSIFLIMNTTKLTVYSRRREVGIMKFVGATDWFIRWPFIIEGMVIGVLGSTLSCIVL
HHHHHHHHHHCCHHEEEEHHHHHHHHHHHHCCCHHHEECHHHHHHHHHHHHHHHHHHHHH
FFAYKGVFSWIASMMMFVTLVPPIYILKVVLLEFIIGGILVGGIASASALRKFLIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRINTFTYFIKDAFTSLKRNRTISFASILTVLITFFVLGIFILLAGNVNQAISSVQDKVD
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LEVFLKDDIKLIDQREIELKLRELEGVKDVVYKSKEEAYKKVQDTTSENEGLLQGYTLEH
HHEEEHHHHHHHCCHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHCCCCCCCCEECEEECC
NPFPASFTVKLESPEYAENISQALDGFTGVEKIDNQKKVVDGIVKLVKGINIVGGALFIV
CCCCCEEEEEECCCHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHH
LVGVSIFLIMNTTKLTVYSRRREVGIMKFVGATDWFIRWPFIIEGMVIGVLGSTLSCIVL
HHHHHHHHHHCCHHEEEEHHHHHHHHHHHHCCCHHHEECHHHHHHHHHHHHHHHHHHHHH
FFAYKGVFSWIASMMMFVTLVPPIYILKVVLLEFIIGGILVGGIASASALRKFLIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]