Click here to switch to the map view.

The map label for this gene is fhuB [H]

Identifier: 187933044

GI number: 187933044

Start: 2212289

End: 2213302

Strand: Reverse

Name: fhuB [H]

Synonym: CLL_A2115

Alternate gene names: 187933044

Gene position: 2213302-2212289 (Counterclockwise)

Preceding gene: 187935398

Following gene: 187934017

Centisome position: 58.24

GC content: 31.16

Gene sequence:

>1014_bases
ATGAAGAAATTTAATAAAAAAACTTTAGCGTATATATTTATGGTTATAGGAATTATGCTTCTTATATTTGGAATAGTTAT
GTCTGTTTCATTAGGAGCAAAAGATATAGATTTTTTAACAATAATAAAAAGTTTGGCTACGGATAACAATGATGTAAATA
CAAAAATAGTTAGAGATGTTAGAATACCTAGAGCTATTGCAGCTTCCCTTGTAGGGGGATTTTTAGCAGTAGCAGGTGCG
ATAATGCAAGGTATAACTAGAAATCCTATAGCAGAACCATCTGTAATGGGAATAACACAAGGTGCTACATTTATGATAGC
AGTAACTTTTGTATTACAAAGAATATATCCAAATTTAGTTGTAGGAAGTTTTGGAATTATGATATTTGCTTTTATTGGAG
CTAGTATAAGCGGACTTTTAGTATATTTTATAAGCTCAAAATCAGCAAGAAAAGTAGATACGGTAAAACTTGCTCTTGCA
GGGACTGCATTAGGTACATTATTAATATCTTTAGCGATGGGAATAGCTATGTATTTTAACCTATCTCAACAGCTAAGCTT
TTGGATTTCAGGAGGATTAGTTAGTGCTAAGTGGGAAGGTGTGAAATTACTATCTATAGTTGGAGGAAGTGCATTAATAG
GAGCTATGATTATGGCACCTAAAATAACTATTTTAAGTTTAGGTGAAGAAGTAGCAATAGGATTAGGACAAAAAACCAAT
GCAGTAAGATTTATAAGCATAATAATAGTAATATTTTTAACAGGAGCATCTGTTTCAGTGGCAGGAAATATAGTGTTTAT
AGGATTAATAGTTCCTCAAATCGCTAAAGCAATAGTAGGAGCAGATTACAAGTATATAATACCTAGTTCAATGATTCTAG
GTTCAGTTTTACTTGTGTATAGTGATATTTTAGCTAGAATGATTAATCCTCCATATGAAACTCCAATTGGTTCTTTAACT
GCATTATTAGGAGTTCCTATGTTTATATATCTTGTTAGAAAGGATAAGAAATAG

Upstream 100 bases:

>100_bases
GTTGTAAAATAATACAAGTATATAGAGTAGGTGGTGAGAGGAGCAACCCTTTTGTCACCTACTATTTGAATTTATAGATA
AATTAGTTTGAGGAGAAGCT

Downstream 100 bases:

>100_bases
ATGATAAATATAGATAAAAATAAAAGATTTACATTAATTATAGGTGTTTTAATGATACTAATAATTACTACAATTTTGAT
TGGTTTAAATATGGGCTCTC

Product: ferrichrome transport system permease protein FhuB

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: Ferric hydroxamate uptake protein B; Ferrichrome transport system permease protein fhuB; Iron(III)-hydroxamate import system permease protein fhuB [H]

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MKKFNKKTLAYIFMVIGIMLLIFGIVMSVSLGAKDIDFLTIIKSLATDNNDVNTKIVRDVRIPRAIAASLVGGFLAVAGA
IMQGITRNPIAEPSVMGITQGATFMIAVTFVLQRIYPNLVVGSFGIMIFAFIGASISGLLVYFISSKSARKVDTVKLALA
GTALGTLLISLAMGIAMYFNLSQQLSFWISGGLVSAKWEGVKLLSIVGGSALIGAMIMAPKITILSLGEEVAIGLGQKTN
AVRFISIIIVIFLTGASVSVAGNIVFIGLIVPQIAKAIVGADYKYIIPSSMILGSVLLVYSDILARMINPPYETPIGSLT
ALLGVPMFIYLVRKDKK

Sequences:

>Translated_337_residues
MKKFNKKTLAYIFMVIGIMLLIFGIVMSVSLGAKDIDFLTIIKSLATDNNDVNTKIVRDVRIPRAIAASLVGGFLAVAGA
IMQGITRNPIAEPSVMGITQGATFMIAVTFVLQRIYPNLVVGSFGIMIFAFIGASISGLLVYFISSKSARKVDTVKLALA
GTALGTLLISLAMGIAMYFNLSQQLSFWISGGLVSAKWEGVKLLSIVGGSALIGAMIMAPKITILSLGEEVAIGLGQKTN
AVRFISIIIVIFLTGASVSVAGNIVFIGLIVPQIAKAIVGADYKYIIPSSMILGSVLLVYSDILARMINPPYETPIGSLT
ALLGVPMFIYLVRKDKK
>Mature_337_residues
MKKFNKKTLAYIFMVIGIMLLIFGIVMSVSLGAKDIDFLTIIKSLATDNNDVNTKIVRDVRIPRAIAASLVGGFLAVAGA
IMQGITRNPIAEPSVMGITQGATFMIAVTFVLQRIYPNLVVGSFGIMIFAFIGASISGLLVYFISSKSARKVDTVKLALA
GTALGTLLISLAMGIAMYFNLSQQLSFWISGGLVSAKWEGVKLLSIVGGSALIGAMIMAPKITILSLGEEVAIGLGQKTN
AVRFISIIIVIFLTGASVSVAGNIVFIGLIVPQIAKAIVGADYKYIIPSSMILGSVLLVYSDILARMINPPYETPIGSLT
ALLGVPMFIYLVRKDKK

Specific function: Part of the ABC transporter complex fhuBGCD involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790741, Length=280, Percent_Identity=34.6428571428571, Blast_Score=154, Evalue=8e-39,
Organism=Escherichia coli, GI1786805, Length=317, Percent_Identity=32.1766561514196, Blast_Score=141, Evalue=7e-35,
Organism=Escherichia coli, GI1790740, Length=333, Percent_Identity=30.9309309309309, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1788004, Length=287, Percent_Identity=34.4947735191638, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1786347, Length=331, Percent_Identity=29.607250755287, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1786804, Length=314, Percent_Identity=27.3885350318471, Blast_Score=93, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 35790; Mature: 35790

Theoretical pI: Translated: 10.51; Mature: 10.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKFNKKTLAYIFMVIGIMLLIFGIVMSVSLGAKDIDFLTIIKSLATDNNDVNTKIVRDV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHH
RIPRAIAASLVGGFLAVAGAIMQGITRNPIAEPSVMGITQGATFMIAVTFVLQRIYPNLV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHH
VGSFGIMIFAFIGASISGLLVYFISSKSARKVDTVKLALAGTALGTLLISLAMGIAMYFN
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSQQLSFWISGGLVSAKWEGVKLLSIVGGSALIGAMIMAPKITILSLGEEVAIGLGQKTN
HHHHHHHHHCCCEEEECCCCEEEEEHHCCHHHHHHHHHCCCEEEEECCHHHHCCCCCCCC
AVRFISIIIVIFLTGASVSVAGNIVFIGLIVPQIAKAIVGADYKYIIPSSMILGSVLLVY
HHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHH
SDILARMINPPYETPIGSLTALLGVPMFIYLVRKDKK
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKKFNKKTLAYIFMVIGIMLLIFGIVMSVSLGAKDIDFLTIIKSLATDNNDVNTKIVRDV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHH
RIPRAIAASLVGGFLAVAGAIMQGITRNPIAEPSVMGITQGATFMIAVTFVLQRIYPNLV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHH
VGSFGIMIFAFIGASISGLLVYFISSKSARKVDTVKLALAGTALGTLLISLAMGIAMYFN
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSQQLSFWISGGLVSAKWEGVKLLSIVGGSALIGAMIMAPKITILSLGEEVAIGLGQKTN
HHHHHHHHHCCCEEEECCCCEEEEEHHCCHHHHHHHHHCCCEEEEECCHHHHCCCCCCCC
AVRFISIIIVIFLTGASVSVAGNIVFIGLIVPQIAKAIVGADYKYIIPSSMILGSVLLVY
HHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHH
SDILARMINPPYETPIGSLTALLGVPMFIYLVRKDKK
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377; 8388528 [H]