Click here to switch to the map view.

The map label for this gene is luxS [H]

Identifier: 187932450

GI number: 187932450

Start: 3492206

End: 3492658

Strand: Reverse

Name: luxS [H]

Synonym: CLL_A3319

Alternate gene names: 187932450

Gene position: 3492658-3492206 (Counterclockwise)

Preceding gene: 187935188

Following gene: 187934784

Centisome position: 91.9

GC content: 28.48

Gene sequence:

>453_bases
ATGGTTAAAGTAGAAAGTTTTGAATTAGATCACACAAAGGTAAAAGCCCCATATGTAAGAAAATGTGGTTCAGAAAAGGG
TAATAATGGAGATATAGTTTCTAAATTTGATTTAAGATTTTTACAACCAAATGAAAAAGAGATGCCAACAGGTGCAATGC
ATACATTAGAACATTTATTAGCTGGATATATGAGAGAAAAATTAGATGGAATAATAGATATATCTCCTATGGGATGTAGA
ACTGGATTTTATATGGTTGCATGGGGAACTCCTGAAGTGGAGAAAGTAATAGAAGCATTAAATTATTCATTAAATAAAAT
ATTAGAAACAGAAGAAATACCAGCAACAAATAAATTTCAATGTGGGAATTATAGAGATCATTCATTATTTGCAGGAAAAG
AATATATTAAATTAATATTAAAAGAGGGGATTAGTAGTGAAATATATAGATGA

Upstream 100 bases:

>100_bases
GTAGGTATTGTTGATAATTTGATAAGACTTTCAGTTGGTATAGAAAGTATACAAGATATTATTGAGGATTTAGAAAAAGC
ATTAGAATGGGGGAAAATTA

Downstream 100 bases:

>100_bases
TATTAGAAGTCATATAGGAAATACACCTATTATGAAACTAAATAATATGGGAATAAAAGCTGGTGTAAATGTATTTGCTA
AATTAGAATTTTTAAATCCT

Product: S-ribosylhomocysteinase

Products: NA

Alternate protein names: AI-2 synthesis protein; Autoinducer-2 production protein luxS [H]

Number of amino acids: Translated: 150; Mature: 150

Protein sequence:

>150_residues
MVKVESFELDHTKVKAPYVRKCGSEKGNNGDIVSKFDLRFLQPNEKEMPTGAMHTLEHLLAGYMREKLDGIIDISPMGCR
TGFYMVAWGTPEVEKVIEALNYSLNKILETEEIPATNKFQCGNYRDHSLFAGKEYIKLILKEGISSEIYR

Sequences:

>Translated_150_residues
MVKVESFELDHTKVKAPYVRKCGSEKGNNGDIVSKFDLRFLQPNEKEMPTGAMHTLEHLLAGYMREKLDGIIDISPMGCR
TGFYMVAWGTPEVEKVIEALNYSLNKILETEEIPATNKFQCGNYRDHSLFAGKEYIKLILKEGISSEIYR
>Mature_150_residues
MVKVESFELDHTKVKAPYVRKCGSEKGNNGDIVSKFDLRFLQPNEKEMPTGAMHTLEHLLAGYMREKLDGIIDISPMGCR
TGFYMVAWGTPEVEKVIEALNYSLNKILETEEIPATNKFQCGNYRDHSLFAGKEYIKLILKEGISSEIYR

Specific function: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is ca

COG id: COG1854

COG function: function code T; LuxS protein involved in autoinducer AI2 synthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the luxS family [H]

Homologues:

Organism=Escherichia coli, GI1789043, Length=151, Percent_Identity=43.7086092715232, Blast_Score=137, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR003815
- ProDom:   PD013172 [H]

Pfam domain/function: PF02664 LuxS [H]

EC number: =4.4.1.21 [H]

Molecular weight: Translated: 17096; Mature: 17096

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKVESFELDHTKVKAPYVRKCGSEKGNNGDIVSKFDLRFLQPNEKEMPTGAMHTLEHLL
CCCCCCCCCCCCEECCHHHHHCCCCCCCCCCEEEECCEEEECCCCCCCCCHHHHHHHHHH
AGYMREKLDGIIDISPMGCRTGFYMVAWGTPEVEKVIEALNYSLNKILETEEIPATNKFQ
HHHHHHHHCCEECCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEE
CGNYRDHSLFAGKEYIKLILKEGISSEIYR
CCCCCCCCHHHHHHHHHHHHHHCCHHHCCC
>Mature Secondary Structure
MVKVESFELDHTKVKAPYVRKCGSEKGNNGDIVSKFDLRFLQPNEKEMPTGAMHTLEHLL
CCCCCCCCCCCCEECCHHHHHCCCCCCCCCCEEEECCEEEECCCCCCCCCHHHHHHHHHH
AGYMREKLDGIIDISPMGCRTGFYMVAWGTPEVEKVIEALNYSLNKILETEEIPATNKFQ
HHHHHHHHCCEECCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEE
CGNYRDHSLFAGKEYIKLILKEGISSEIYR
CCCCCCCCHHHHHHHHHHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA