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The map label for this gene is insF1 [C]

Identifier: 187928907

GI number: 187928907

Start: 1917862

End: 1918719

Strand: Reverse

Name: insF1 [C]

Synonym: Rpic_1826

Alternate gene names: 187928907

Gene position: 1918719-1917862 (Counterclockwise)

Preceding gene: 187928908

Following gene: 187928906

Centisome position: 48.67

GC content: 63.64

Gene sequence:

>858_bases
GTGTTGCAGGTTGCCTCGTCGGCCTATCGGCGCCATGCCGCACGGCTGCGTGATCCGTCACGGCGCAGCGACCGTGCGCG
TCGTGATGAACGGCTCATGCCGCAAGTCCAGCGAGTGTGGCAGGAGAACCATCGCGTCTACGGCGCCGACAAGGTCTGGC
GGCAACTGAACCGCGAGGGCGTGACGGTTGCCCGCTGCACGGTCGAGCGATTGATGCGCGCCCAGGGACTGCAAGGTGTG
CGGCGCGGCAAGCGGCTGCGAACGACCATCGCTGACGACGCCGCCAGTCGCCCGGTGGATCGCGTCAACCGGCAGTTCCG
GGCCGACCGTCCCAATCAGCTCTGGGTCTCGGACTTCACCTACGTCTCGACATGGCAGGGTTGGCTGTACGTGGCCTTCG
TCGTCGACGTCTACGCCAGGCGCATCGTCGGCTGGCGCGTGAGCAAATCCATGACGACGGACTTCGTGCTCGATGCGCTG
GAGCAGGCCCTATACGCTCGCCAGCCTGGCAACGACGGTTCTCTGACCCACCACTCCGATAGGGGATCGCAGTACGTCAG
CATCCGCTATAGCGAACGCCTGGCCGAAGCCGGCATCGAGCCGTCGGTCGGCAGCCGTGGCGACAGTTACGACAACGCCT
TGGCCGAGACGATCAATGGCTTGTACAAGGCCGAGCTGATCCATCGCCGCGCGCCTTGGAAAACCAGGGAATCCGTCGAA
CTGGCAACACTGGAATGGGTCGCTTGGTTCAACCATAAGCGCCTGCACTCATCCATCGGCTATATCCCGCCCGCCGAGGC
TGAGGCAAACTACTACAACCAACTCGGCAAAACCGCCGACGAGGCCGTTTTACTTTAA

Upstream 100 bases:

>100_bases
GCGCTTTTTTCGCGCAGGCGGAGCTCGACCGCAAGCTGAAGTCGTAAACACCTACATCGACCGGCACCGGGAGGTTTACG
GGGTCGAGCCGATCTGCAAG

Downstream 100 bases:

>100_bases
CCAAACAGCCTCCGCGAAAACCGGGGCGATTCAGTCCCGTTGGTTCAGCGCCAGGCTTCAGCATCTGGGTCCCGTTGACC
CCGGGCGCCTTCTGGCAACG

Product: Integrase catalytic subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MLQVASSAYRRHAARLRDPSRRSDRARRDERLMPQVQRVWQENHRVYGADKVWRQLNREGVTVARCTVERLMRAQGLQGV
RRGKRLRTTIADDAASRPVDRVNRQFRADRPNQLWVSDFTYVSTWQGWLYVAFVVDVYARRIVGWRVSKSMTTDFVLDAL
EQALYARQPGNDGSLTHHSDRGSQYVSIRYSERLAEAGIEPSVGSRGDSYDNALAETINGLYKAELIHRRAPWKTRESVE
LATLEWVAWFNHKRLHSSIGYIPPAEAEANYYNQLGKTADEAVLL

Sequences:

>Translated_285_residues
MLQVASSAYRRHAARLRDPSRRSDRARRDERLMPQVQRVWQENHRVYGADKVWRQLNREGVTVARCTVERLMRAQGLQGV
RRGKRLRTTIADDAASRPVDRVNRQFRADRPNQLWVSDFTYVSTWQGWLYVAFVVDVYARRIVGWRVSKSMTTDFVLDAL
EQALYARQPGNDGSLTHHSDRGSQYVSIRYSERLAEAGIEPSVGSRGDSYDNALAETINGLYKAELIHRRAPWKTRESVE
LATLEWVAWFNHKRLHSSIGYIPPAEAEANYYNQLGKTADEAVLL
>Mature_285_residues
MLQVASSAYRRHAARLRDPSRRSDRARRDERLMPQVQRVWQENHRVYGADKVWRQLNREGVTVARCTVERLMRAQGLQGV
RRGKRLRTTIADDAASRPVDRVNRQFRADRPNQLWVSDFTYVSTWQGWLYVAFVVDVYARRIVGWRVSKSMTTDFVLDAL
EQALYARQPGNDGSLTHHSDRGSQYVSIRYSERLAEAGIEPSVGSRGDSYDNALAETINGLYKAELIHRRAPWKTRESVE
LATLEWVAWFNHKRLHSSIGYIPPAEAEANYYNQLGKTADEAVLL

Specific function: Involved in the transposition of the insertion sequence [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=240, Percent_Identity=53.3333333333333, Blast_Score=248, Evalue=4e-66,
Organism=Escherichia coli, GI1788405, Length=258, Percent_Identity=31.7829457364341, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1787263, Length=258, Percent_Identity=31.7829457364341, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1786753, Length=258, Percent_Identity=31.7829457364341, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1786570, Length=258, Percent_Identity=31.7829457364341, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1786490, Length=258, Percent_Identity=31.7829457364341, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1789981, Length=264, Percent_Identity=27.2727272727273, Blast_Score=113, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 32890; Mature: 32890

Theoretical pI: Translated: 10.31; Mature: 10.31

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQVASSAYRRHAARLRDPSRRSDRARRDERLMPQVQRVWQENHRVYGADKVWRQLNREG
CCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEECHHHHHHHHCCCC
VTVARCTVERLMRAQGLQGVRRGKRLRTTIADDAASRPVDRVNRQFRADRPNQLWVSDFT
CCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCEEECCCCH
YVSTWQGWLYVAFVVDVYARRIVGWRVSKSMTTDFVLDALEQALYARQPGNDGSLTHHSD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
RGSQYVSIRYSERLAEAGIEPSVGSRGDSYDNALAETINGLYKAELIHRRAPWKTRESVE
CCCEEEEEEHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
LATLEWVAWFNHKRLHSSIGYIPPAEAEANYYNQLGKTADEAVLL
HHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCHHHHCCC
>Mature Secondary Structure
MLQVASSAYRRHAARLRDPSRRSDRARRDERLMPQVQRVWQENHRVYGADKVWRQLNREG
CCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEECHHHHHHHHCCCC
VTVARCTVERLMRAQGLQGVRRGKRLRTTIADDAASRPVDRVNRQFRADRPNQLWVSDFT
CCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCEEECCCCH
YVSTWQGWLYVAFVVDVYARRIVGWRVSKSMTTDFVLDALEQALYARQPGNDGSLTHHSD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
RGSQYVSIRYSERLAEAGIEPSVGSRGDSYDNALAETINGLYKAELIHRRAPWKTRESVE
CCCEEEEEEHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
LATLEWVAWFNHKRLHSSIGYIPPAEAEANYYNQLGKTADEAVLL
HHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2159625; 2824781 [H]