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The map label for this gene is hmrR2 [H]

Identifier: 187928887

GI number: 187928887

Start: 1896327

End: 1896755

Strand: Reverse

Name: hmrR2 [H]

Synonym: Rpic_1805

Alternate gene names: 187928887

Gene position: 1896755-1896327 (Counterclockwise)

Preceding gene: 187928896

Following gene: 187928886

Centisome position: 48.11

GC content: 60.84

Gene sequence:

>429_bases
ATGAATATTGGACAAGCCGCGAGCGTCTCGGGCGTCTCGGCCAAAATGATCCGCTACTACGAAAGTATTGGCTTAGTCGC
ATCAGCTACCCGGAGCGAGGGGAACTACCGAATGTATCGTGAAAACGACATTCACACCCTGCGCTTCATCGGGCGTGCGC
GGGCGTTAGGTTTCTCCACGGCGCAGATTCGAGAGCTGCTCGGGCTGTGGCAAGACAAGCGCCGCACGCGCGCAACAGTG
AAGGCCATCGCGTTACAGCGCATCCAGGAACTGGACGCTCGGATTGCCGCGCTCAGCGACATGCGGGACACCCTGCTGTA
TCTGGCACAGCATTGTGACGGTGACGATCGCCCCGCCTGCCCGATCCTGGAGGCGATCAGCAGCGTCGCCCCACGGCAAT
TACCTGCCCCGCAGGCCACGAGACATTGA

Upstream 100 bases:

>100_bases
CGTGAAACCGTGAAGATTTTGGGTACGCGTCGGTCCCGCGGAAGATGCTACGAACACGGAATACCGAAGCTGCCACGCGC
ACAGGAGCGAGGAGCACGTC

Downstream 100 bases:

>100_bases
GGCAGCGCAAAAATGAATGATCAACGATCGCATCCGCAGACGCCATCCCCTGCACCCGGCCACGTCAAAGGTGTGGAATG
CGGAAATTCGTGCACAGAAG

Product: MerR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 142; Mature: 142

Protein sequence:

>142_residues
MNIGQAASVSGVSAKMIRYYESIGLVASATRSEGNYRMYRENDIHTLRFIGRARALGFSTAQIRELLGLWQDKRRTRATV
KAIALQRIQELDARIAALSDMRDTLLYLAQHCDGDDRPACPILEAISSVAPRQLPAPQATRH

Sequences:

>Translated_142_residues
MNIGQAASVSGVSAKMIRYYESIGLVASATRSEGNYRMYRENDIHTLRFIGRARALGFSTAQIRELLGLWQDKRRTRATV
KAIALQRIQELDARIAALSDMRDTLLYLAQHCDGDDRPACPILEAISSVAPRQLPAPQATRH
>Mature_142_residues
MNIGQAASVSGVSAKMIRYYESIGLVASATRSEGNYRMYRENDIHTLRFIGRARALGFSTAQIRELLGLWQDKRRTRATV
KAIALQRIQELDARIAALSDMRDTLLYLAQHCDGDDRPACPILEAISSVAPRQLPAPQATRH

Specific function: Transcriptional regulator involved in acid tolerance. Binds copper [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786695, Length=130, Percent_Identity=40, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1789687, Length=131, Percent_Identity=40.4580152671756, Blast_Score=91, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011789
- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 15826; Mature: 15826

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIGQAASVSGVSAKMIRYYESIGLVASATRSEGNYRMYRENDIHTLRFIGRARALGFST
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHCCCCH
AQIRELLGLWQDKRRTRATVKAIALQRIQELDARIAALSDMRDTLLYLAQHCDGDDRPAC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PILEAISSVAPRQLPAPQATRH
HHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MNIGQAASVSGVSAKMIRYYESIGLVASATRSEGNYRMYRENDIHTLRFIGRARALGFST
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHCCCCH
AQIRELLGLWQDKRRTRATVKAIALQRIQELDARIAALSDMRDTLLYLAQHCDGDDRPAC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PILEAISSVAPRQLPAPQATRH
HHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481431 [H]