BacMap

Definition	Ralstonia pickettii 12J chromosome chromosome 1, complete sequence.
Accession	NC_010682
Length	3,942,557

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The map label for this gene is ftsH

Identifier: 187928785

GI number: 187928785

Start: 1793426

End: 1795570

Strand: Reverse

Name: ftsH

Synonym: Rpic_1702

Alternate gene names: 187928785

Gene position: 1795570-1793426 (Counterclockwise)

Preceding gene: 187928798

Following gene: 187928782

Centisome position: 45.54

GC content: 58.6

Gene sequence:

>2145_bases
ATGGAGAAGCCACGGCGCTTGCGCCCGCGCGCGCGGCCCCAATGTCGCGGGTTGATGAAGGTCAACCTCGGCGATTTCCA
AGCGTCAATACTGGGAACGCATACCAATGCGCGGTTGTCCGGCGCCTACCCAGGCCGCCCACCAACCTTCCCAGCATTGG
AGACCAGACTCACTTTCAATAAGGTCGACTTGGAGAAGAATCCCATGGAACCGCGACAGCAACAGTTCTCCCTCTGGTAC
GTGCTCGTGACCATACTGGCCATGCTTGCAATCCAGACGCTCTTCGTGTCGGGGCATGTCGAGACGATCCCATACAGCGA
TTTCAAGGTCCTACTGAAGGCTGGCAAGCTCAAGGACGTGGCTATTGGTGAGCAGGCTATCAGCGGAACCTTCTCGACAG
AAGGTATCGACAATCTCCTTGCCAAGCAGCAGATCGAGGAAATCCGCCGAGAGGCAAAGGGCGACCACGCCTTCTCCACG
CTTCGAGTGGCCGATCCTGAGCTGGTGCAGGAGCTCGAAGCGGCAAAGGTGCGCTTCGTCGGGCAGCCCGACAACAAATG
GCTGAGCACGATCCTCTCGTGGGTTGTGCCGGCCGTCATCTTTTTCGGTATCTGGAGCTTTCTCATCAAGCGCGTGGGCG
GCGCCGCCGGCAGCATGATGGAAATTGGCAAGAGCAAGGCAAAGGTCTACATGCAAAAGGAGACCGGCGTGACTTTTGCC
GACGTGGCTGGAATCGACGAAGCCAAGGAGGAGCTGTCGGAGATTGTTAGCTTCCTGAAAGATCCTCAGCGGTACCAGCG
CCTGGGCGGAAAAATTCCCAAGGGCGTGCTGCTGGTTGGGGCCCCGGGCACTGGCAAGACCTTATTGGCAAAGGCCGTGG
CAGGCGAAGCCGGCGTGCCATTCTTCAGCATGAGCGGCTCCGACTTCGTCGAGATGTTCGTTGGTGTGGGTGCAGCACGG
GTCCGCGATCTCTTTAAGCAAGCCGAAACCAAAGCCCCCTGCATCATCTTCATTGATGAGCTTGACGCACTCGGAAAGAC
GCGAGCACTGAATGCGGTCGGCGGCAACGAGGAGCGCGAACAAACACTGAACCAGCTTCTGGTCGAGATGGACGGTTTTG
ATAGCAACAAAGGCGTCATCATCATGGCCGCCACAAACCGACCCGAGATACTGGACCCCGCCCTGCTTCGCCCCGGTCGC
TTTGACCGCCACGTCGCACTGGACCGGCCTGACCTCAAGGGACGGGAGCAGATTCTCAAAGTTCACGTCAAGGGCGTTGT
CCTCGCTCCTGAGGTCGACCTGACTAAACTCGCCGGACGGACCCCGGGGTTCGCAGGTGCCGATCTTGCCAACTTGGTTA
ACGAAGCCGCGCTCCTTGCCGCGCGCAAGAGCAAGCAAATGGTCGAGATGGCAGATTTCGACGAGGCGCTTGACCGGATC
GTCGGCGGCCTGGAAAAAAAGAACCGCGTGATGAATCCGAAGGAGAAGGAAACTATCGCATTCCACGAGGCAGGACATGC
CATCGTCGCGGAGCATCGGCCGCTGGCTGACCGTGTCTCCAAAGTTTCCATCATTCCGCGGGGCGTTGCGGCGTTGGGTT
ACACGCAACAGACCCCAACCGAGGACCGCTACCTGCTCAAGCGCAGCGAACTGCTTGACCGGCTCGATGTCTTGCTCGGT
GGCCGTATTGCGGAACAGCTCATTTTCGGCGACGTATCCACGGGCGCACAGAACGACCTGCAGCGCGCAACCGACATGGC
TCGGCAGATGATTACCCAGTTTGGCATGAGCGACCAGCTGGGCCTGGCCACGTACGAGAATATGCCGAACCCGCTCTTTG
CTGGGACGGGGCTAATGCAGCGCGAACGCAATGAATACAGCGAGAGCACCGCACAGATGATTGATGCTGAAGTCCGTAAG
CTATTGGCAGAAGCAAGTCATCGCGTACAAGCGACGCTGGAAGGACAGCGGACCAAGCTCGATGCTCTGGCCCAATTACT
TCTCGAGAAGGAAGTGGTTGACCGCCAAGACCTGGACATGTTTTTGTCAGCGAAGGTGACGCCAATGCCTCCGCCCAAGC
CCGTCGCGAATATCGAGGAGTCAACTGCAACGGGGAAACCGGACCAAAAAACGCAAGGCACATAG

Upstream 100 bases:

>100_bases
TACTTTGCGCCAGCGCAAGTTGCTGTTGAGTCTCATGCCGCCGTAATGGATTTGTCATGTTTGCTTTCCGCGACACATCC
CCTATCGGCTGGGCACAACC

Downstream 100 bases:

>100_bases
AGCGAAGATTGATGCCATGGCATGCCAAGAACGCAACCACGCCAAAGCGCGGCCGGCTGCCGGCAATCAATGCGTTCACC
ACGTGAGACAGGCGCCCCGA

Product: ATP-dependent metalloprotease FtsH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 714; Mature: 714

Protein sequence:

>714_residues
MEKPRRLRPRARPQCRGLMKVNLGDFQASILGTHTNARLSGAYPGRPPTFPALETRLTFNKVDLEKNPMEPRQQQFSLWY
VLVTILAMLAIQTLFVSGHVETIPYSDFKVLLKAGKLKDVAIGEQAISGTFSTEGIDNLLAKQQIEEIRREAKGDHAFST
LRVADPELVQELEAAKVRFVGQPDNKWLSTILSWVVPAVIFFGIWSFLIKRVGGAAGSMMEIGKSKAKVYMQKETGVTFA
DVAGIDEAKEELSEIVSFLKDPQRYQRLGGKIPKGVLLVGAPGTGKTLLAKAVAGEAGVPFFSMSGSDFVEMFVGVGAAR
VRDLFKQAETKAPCIIFIDELDALGKTRALNAVGGNEEREQTLNQLLVEMDGFDSNKGVIIMAATNRPEILDPALLRPGR
FDRHVALDRPDLKGREQILKVHVKGVVLAPEVDLTKLAGRTPGFAGADLANLVNEAALLAARKSKQMVEMADFDEALDRI
VGGLEKKNRVMNPKEKETIAFHEAGHAIVAEHRPLADRVSKVSIIPRGVAALGYTQQTPTEDRYLLKRSELLDRLDVLLG
GRIAEQLIFGDVSTGAQNDLQRATDMARQMITQFGMSDQLGLATYENMPNPLFAGTGLMQRERNEYSESTAQMIDAEVRK
LLAEASHRVQATLEGQRTKLDALAQLLLEKEVVDRQDLDMFLSAKVTPMPPPKPVANIEESTATGKPDQKTQGT

Sequences:

>Translated_714_residues
MEKPRRLRPRARPQCRGLMKVNLGDFQASILGTHTNARLSGAYPGRPPTFPALETRLTFNKVDLEKNPMEPRQQQFSLWY
VLVTILAMLAIQTLFVSGHVETIPYSDFKVLLKAGKLKDVAIGEQAISGTFSTEGIDNLLAKQQIEEIRREAKGDHAFST
LRVADPELVQELEAAKVRFVGQPDNKWLSTILSWVVPAVIFFGIWSFLIKRVGGAAGSMMEIGKSKAKVYMQKETGVTFA
DVAGIDEAKEELSEIVSFLKDPQRYQRLGGKIPKGVLLVGAPGTGKTLLAKAVAGEAGVPFFSMSGSDFVEMFVGVGAAR
VRDLFKQAETKAPCIIFIDELDALGKTRALNAVGGNEEREQTLNQLLVEMDGFDSNKGVIIMAATNRPEILDPALLRPGR
FDRHVALDRPDLKGREQILKVHVKGVVLAPEVDLTKLAGRTPGFAGADLANLVNEAALLAARKSKQMVEMADFDEALDRI
VGGLEKKNRVMNPKEKETIAFHEAGHAIVAEHRPLADRVSKVSIIPRGVAALGYTQQTPTEDRYLLKRSELLDRLDVLLG
GRIAEQLIFGDVSTGAQNDLQRATDMARQMITQFGMSDQLGLATYENMPNPLFAGTGLMQRERNEYSESTAQMIDAEVRK
LLAEASHRVQATLEGQRTKLDALAQLLLEKEVVDRQDLDMFLSAKVTPMPPPKPVANIEESTATGKPDQKTQGT
>Mature_714_residues
MEKPRRLRPRARPQCRGLMKVNLGDFQASILGTHTNARLSGAYPGRPPTFPALETRLTFNKVDLEKNPMEPRQQQFSLWY
VLVTILAMLAIQTLFVSGHVETIPYSDFKVLLKAGKLKDVAIGEQAISGTFSTEGIDNLLAKQQIEEIRREAKGDHAFST
LRVADPELVQELEAAKVRFVGQPDNKWLSTILSWVVPAVIFFGIWSFLIKRVGGAAGSMMEIGKSKAKVYMQKETGVTFA
DVAGIDEAKEELSEIVSFLKDPQRYQRLGGKIPKGVLLVGAPGTGKTLLAKAVAGEAGVPFFSMSGSDFVEMFVGVGAAR
VRDLFKQAETKAPCIIFIDELDALGKTRALNAVGGNEEREQTLNQLLVEMDGFDSNKGVIIMAATNRPEILDPALLRPGR
FDRHVALDRPDLKGREQILKVHVKGVVLAPEVDLTKLAGRTPGFAGADLANLVNEAALLAARKSKQMVEMADFDEALDRI
VGGLEKKNRVMNPKEKETIAFHEAGHAIVAEHRPLADRVSKVSIIPRGVAALGYTQQTPTEDRYLLKRSELLDRLDVLLG
GRIAEQLIFGDVSTGAQNDLQRATDMARQMITQFGMSDQLGLATYENMPNPLFAGTGLMQRERNEYSESTAQMIDAEVRK
LLAEASHRVQATLEGQRTKLDALAQLLLEKEVVDRQDLDMFLSAKVTPMPPPKPVANIEESTATGKPDQKTQGT

Specific function: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins

COG id: COG0465

COG function: function code O; ATP-dependent Zn proteases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the peptidase M41 family

Homologues:

Organism=Homo sapiens, GI300192933, Length=550, Percent_Identity=47.8181818181818, Blast_Score=479, Evalue=1e-135,
Organism=Homo sapiens, GI4507173, Length=460, Percent_Identity=47.1739130434783, Blast_Score=415, Evalue=1e-115,
Organism=Homo sapiens, GI21327685, Length=452, Percent_Identity=47.1238938053097, Blast_Score=402, Evalue=1e-112,
Organism=Homo sapiens, GI7657689, Length=452, Percent_Identity=47.1238938053097, Blast_Score=402, Evalue=1e-112,
Organism=Homo sapiens, GI4506209, Length=257, Percent_Identity=40.4669260700389, Blast_Score=209, Evalue=6e-54,
Organism=Homo sapiens, GI24430151, Length=294, Percent_Identity=38.7755102040816, Blast_Score=207, Evalue=3e-53,
Organism=Homo sapiens, GI195539395, Length=246, Percent_Identity=40.650406504065, Blast_Score=200, Evalue=5e-51,
Organism=Homo sapiens, GI24497435, Length=252, Percent_Identity=40.4761904761905, Blast_Score=197, Evalue=3e-50,
Organism=Homo sapiens, GI45643123, Length=282, Percent_Identity=39.3617021276596, Blast_Score=196, Evalue=7e-50,
Organism=Homo sapiens, GI45643125, Length=282, Percent_Identity=39.3617021276596, Blast_Score=196, Evalue=8e-50,
Organism=Homo sapiens, GI6005942, Length=225, Percent_Identity=43.5555555555556, Blast_Score=192, Evalue=7e-49,
Organism=Homo sapiens, GI89064750, Length=253, Percent_Identity=39.5256916996047, Blast_Score=191, Evalue=2e-48,
Organism=Homo sapiens, GI21361144, Length=240, Percent_Identity=41.25, Blast_Score=191, Evalue=2e-48,
Organism=Homo sapiens, GI5729991, Length=253, Percent_Identity=39.5256916996047, Blast_Score=191, Evalue=3e-48,
Organism=Homo sapiens, GI24430155, Length=253, Percent_Identity=39.5256916996047, Blast_Score=190, Evalue=4e-48,
Organism=Homo sapiens, GI157671927, Length=269, Percent_Identity=37.546468401487, Blast_Score=179, Evalue=9e-45,
Organism=Homo sapiens, GI40806173, Length=138, Percent_Identity=63.0434782608696, Blast_Score=178, Evalue=2e-44,
Organism=Homo sapiens, GI229577436, Length=244, Percent_Identity=39.7540983606557, Blast_Score=166, Evalue=7e-41,
Organism=Homo sapiens, GI24497618, Length=266, Percent_Identity=37.218045112782, Blast_Score=162, Evalue=1e-39,
Organism=Homo sapiens, GI4505725, Length=236, Percent_Identity=36.864406779661, Blast_Score=160, Evalue=4e-39,
Organism=Homo sapiens, GI153792536, Length=325, Percent_Identity=32.9230769230769, Blast_Score=156, Evalue=7e-38,
Organism=Homo sapiens, GI194018488, Length=268, Percent_Identity=37.6865671641791, Blast_Score=149, Evalue=7e-36,
Organism=Homo sapiens, GI5901990, Length=240, Percent_Identity=39.1666666666667, Blast_Score=148, Evalue=2e-35,
Organism=Homo sapiens, GI14149767, Length=292, Percent_Identity=34.5890410958904, Blast_Score=147, Evalue=5e-35,
Organism=Homo sapiens, GI62177112, Length=292, Percent_Identity=34.5890410958904, Blast_Score=147, Evalue=5e-35,
Organism=Homo sapiens, GI17865802, Length=234, Percent_Identity=37.6068376068376, Blast_Score=138, Evalue=2e-32,
Organism=Homo sapiens, GI31377644, Length=234, Percent_Identity=37.1794871794872, Blast_Score=137, Evalue=4e-32,
Organism=Homo sapiens, GI7019569, Length=240, Percent_Identity=36.25, Blast_Score=134, Evalue=3e-31,
Organism=Homo sapiens, GI226371754, Length=260, Percent_Identity=33.8461538461538, Blast_Score=130, Evalue=4e-30,
Organism=Homo sapiens, GI31742536, Length=226, Percent_Identity=35.3982300884956, Blast_Score=130, Evalue=4e-30,
Organism=Homo sapiens, GI112789543, Length=226, Percent_Identity=35.3982300884956, Blast_Score=130, Evalue=4e-30,
Organism=Homo sapiens, GI11875211, Length=264, Percent_Identity=37.8787878787879, Blast_Score=129, Evalue=8e-30,
Organism=Homo sapiens, GI40806170, Length=264, Percent_Identity=37.8787878787879, Blast_Score=129, Evalue=1e-29,
Organism=Homo sapiens, GI156564401, Length=262, Percent_Identity=34.3511450381679, Blast_Score=124, Evalue=3e-28,
Organism=Homo sapiens, GI310125282, Length=262, Percent_Identity=33.969465648855, Blast_Score=121, Evalue=3e-27,
Organism=Homo sapiens, GI310125280, Length=209, Percent_Identity=35.8851674641148, Blast_Score=119, Evalue=1e-26,
Organism=Homo sapiens, GI64084766, Length=271, Percent_Identity=27.6752767527675, Blast_Score=96, Evalue=2e-19,
Organism=Homo sapiens, GI75677353, Length=196, Percent_Identity=32.6530612244898, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI283436222, Length=198, Percent_Identity=30.8080808080808, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI283436224, Length=198, Percent_Identity=30.8080808080808, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI283436220, Length=198, Percent_Identity=30.8080808080808, Blast_Score=78, Evalue=3e-14,
Organism=Homo sapiens, GI116292174, Length=249, Percent_Identity=30.1204819277108, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI194018490, Length=161, Percent_Identity=32.9192546583851, Blast_Score=71, Evalue=3e-12,
Organism=Escherichia coli, GI1789568, Length=565, Percent_Identity=49.2035398230089, Blast_Score=529, Evalue=1e-151,
Organism=Caenorhabditis elegans, GI71994521, Length=459, Percent_Identity=51.4161220043573, Blast_Score=442, Evalue=1e-124,
Organism=Caenorhabditis elegans, GI17554264, Length=460, Percent_Identity=46.304347826087, Blast_Score=396, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI115534323, Length=455, Percent_Identity=44.3956043956044, Blast_Score=386, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI17563248, Length=257, Percent_Identity=42.4124513618677, Blast_Score=211, Evalue=9e-55,
Organism=Caenorhabditis elegans, GI17554786, Length=252, Percent_Identity=41.6666666666667, Blast_Score=209, Evalue=6e-54,
Organism=Caenorhabditis elegans, GI25144278, Length=328, Percent_Identity=36.5853658536585, Blast_Score=207, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI25144281, Length=328, Percent_Identity=36.5853658536585, Blast_Score=207, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI17563250, Length=252, Percent_Identity=41.6666666666667, Blast_Score=206, Evalue=3e-53,
Organism=Caenorhabditis elegans, GI17505546, Length=245, Percent_Identity=41.6326530612245, Blast_Score=197, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI71987364, Length=246, Percent_Identity=39.8373983739837, Blast_Score=196, Evalue=4e-50,
Organism=Caenorhabditis elegans, GI17532375, Length=232, Percent_Identity=42.6724137931034, Blast_Score=196, Evalue=4e-50,
Organism=Caenorhabditis elegans, GI71987372, Length=246, Percent_Identity=39.8373983739837, Blast_Score=196, Evalue=4e-50,
Organism=Caenorhabditis elegans, GI17531535, Length=231, Percent_Identity=43.2900432900433, Blast_Score=192, Evalue=7e-49,
Organism=Caenorhabditis elegans, GI17508701, Length=240, Percent_Identity=40.4166666666667, Blast_Score=185, Evalue=6e-47,
Organism=Caenorhabditis elegans, GI17554784, Length=246, Percent_Identity=38.2113821138211, Blast_Score=172, Evalue=4e-43,
Organism=Caenorhabditis elegans, GI17508053, Length=254, Percent_Identity=38.1889763779528, Blast_Score=167, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17537217, Length=267, Percent_Identity=37.8277153558052, Blast_Score=162, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI193206116, Length=250, Percent_Identity=38, Blast_Score=154, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI193206114, Length=250, Percent_Identity=38, Blast_Score=154, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI133931034, Length=250, Percent_Identity=38, Blast_Score=154, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI25153574, Length=229, Percent_Identity=38.8646288209607, Blast_Score=154, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI193209502, Length=226, Percent_Identity=38.9380530973451, Blast_Score=150, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI17570397, Length=152, Percent_Identity=46.7105263157895, Blast_Score=146, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI32566590, Length=152, Percent_Identity=46.7105263157895, Blast_Score=146, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI86561515, Length=240, Percent_Identity=37.0833333333333, Blast_Score=139, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI17562804, Length=242, Percent_Identity=33.8842975206612, Blast_Score=135, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI25146157, Length=267, Percent_Identity=36.7041198501873, Blast_Score=133, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI32563584, Length=236, Percent_Identity=37.7118644067797, Blast_Score=127, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17508421, Length=236, Percent_Identity=37.7118644067797, Blast_Score=127, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI133901658, Length=298, Percent_Identity=33.2214765100671, Blast_Score=124, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI133901662, Length=298, Percent_Identity=33.2214765100671, Blast_Score=124, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17560432, Length=271, Percent_Identity=33.5793357933579, Blast_Score=121, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17541226, Length=280, Percent_Identity=29.6428571428571, Blast_Score=110, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17541224, Length=261, Percent_Identity=31.0344827586207, Blast_Score=110, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI71990294, Length=198, Percent_Identity=29.2929292929293, Blast_Score=77, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17570511, Length=67, Percent_Identity=49.2537313432836, Blast_Score=75, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6323736, Length=512, Percent_Identity=47.65625, Blast_Score=480, Evalue=1e-136,
Organism=Saccharomyces cerevisiae, GI6320854, Length=544, Percent_Identity=45.0367647058824, Blast_Score=458, Evalue=1e-129,
Organism=Saccharomyces cerevisiae, GI6325281, Length=495, Percent_Identity=45.8585858585859, Blast_Score=409, Evalue=1e-115,
Organism=Saccharomyces cerevisiae, GI6322704, Length=266, Percent_Identity=40.6015037593985, Blast_Score=211, Evalue=2e-55,
Organism=Saccharomyces cerevisiae, GI6320197, Length=310, Percent_Identity=37.0967741935484, Blast_Score=205, Evalue=2e-53,
Organism=Saccharomyces cerevisiae, GI6321390, Length=246, Percent_Identity=39.8373983739837, Blast_Score=197, Evalue=4e-51,
Organism=Saccharomyces cerevisiae, GI6324833, Length=245, Percent_Identity=42.4489795918367, Blast_Score=197, Evalue=7e-51,
Organism=Saccharomyces cerevisiae, GI6320077, Length=235, Percent_Identity=43.8297872340426, Blast_Score=193, Evalue=7e-50,
Organism=Saccharomyces cerevisiae, GI6324691, Length=244, Percent_Identity=41.3934426229508, Blast_Score=191, Evalue=3e-49,
Organism=Saccharomyces cerevisiae, GI6320602, Length=244, Percent_Identity=42.6229508196721, Blast_Score=189, Evalue=1e-48,
Organism=Saccharomyces cerevisiae, GI6323429, Length=271, Percent_Identity=38.3763837638376, Blast_Score=175, Evalue=3e-44,
Organism=Saccharomyces cerevisiae, GI6322994, Length=232, Percent_Identity=39.2241379310345, Blast_Score=170, Evalue=6e-43,
Organism=Saccharomyces cerevisiae, GI6322651, Length=248, Percent_Identity=36.6935483870968, Blast_Score=164, Evalue=6e-41,
Organism=Saccharomyces cerevisiae, GI6321709, Length=275, Percent_Identity=37.0909090909091, Blast_Score=162, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6324000, Length=238, Percent_Identity=39.0756302521008, Blast_Score=161, Evalue=3e-40,
Organism=Saccharomyces cerevisiae, GI6325431, Length=247, Percent_Identity=38.8663967611336, Blast_Score=143, Evalue=7e-35,
Organism=Saccharomyces cerevisiae, GI6321465, Length=280, Percent_Identity=33.9285714285714, Blast_Score=129, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6319554, Length=217, Percent_Identity=35.9447004608295, Blast_Score=125, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6325183, Length=254, Percent_Identity=34.6456692913386, Blast_Score=122, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6320887, Length=247, Percent_Identity=33.1983805668016, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI28574878, Length=459, Percent_Identity=49.4553376906318, Blast_Score=452, Evalue=1e-127,
Organism=Drosophila melanogaster, GI24665814, Length=459, Percent_Identity=49.4553376906318, Blast_Score=452, Evalue=1e-127,
Organism=Drosophila melanogaster, GI24639391, Length=462, Percent_Identity=47.8354978354978, Blast_Score=426, Evalue=1e-119,
Organism=Drosophila melanogaster, GI24658770, Length=505, Percent_Identity=44.3564356435644, Blast_Score=400, Evalue=1e-111,
Organism=Drosophila melanogaster, GI45554047, Length=166, Percent_Identity=59.6385542168675, Blast_Score=208, Evalue=1e-53,
Organism=Drosophila melanogaster, GI24649446, Length=294, Percent_Identity=38.4353741496599, Blast_Score=205, Evalue=1e-52,
Organism=Drosophila melanogaster, GI17137560, Length=230, Percent_Identity=43.4782608695652, Blast_Score=204, Evalue=2e-52,
Organism=Drosophila melanogaster, GI161076486, Length=230, Percent_Identity=43.4782608695652, Blast_Score=204, Evalue=2e-52,
Organism=Drosophila melanogaster, GI161076488, Length=230, Percent_Identity=43.4782608695652, Blast_Score=204, Evalue=3e-52,
Organism=Drosophila melanogaster, GI17137738, Length=251, Percent_Identity=40.6374501992032, Blast_Score=202, Evalue=8e-52,
Organism=Drosophila melanogaster, GI24660075, Length=266, Percent_Identity=41.7293233082707, Blast_Score=201, Evalue=1e-51,
Organism=Drosophila melanogaster, GI281365776, Length=266, Percent_Identity=41.7293233082707, Blast_Score=201, Evalue=1e-51,
Organism=Drosophila melanogaster, GI19920408, Length=252, Percent_Identity=40.8730158730159, Blast_Score=201, Evalue=1e-51,
Organism=Drosophila melanogaster, GI45552965, Length=266, Percent_Identity=41.7293233082707, Blast_Score=201, Evalue=2e-51,
Organism=Drosophila melanogaster, GI24651451, Length=252, Percent_Identity=40.0793650793651, Blast_Score=192, Evalue=5e-49,
Organism=Drosophila melanogaster, GI17738151, Length=240, Percent_Identity=41.25, Blast_Score=192, Evalue=1e-48,
Organism=Drosophila melanogaster, GI24640100, Length=245, Percent_Identity=40.4081632653061, Blast_Score=191, Evalue=1e-48,
Organism=Drosophila melanogaster, GI24663015, Length=256, Percent_Identity=38.671875, Blast_Score=185, Evalue=1e-46,
Organism=Drosophila melanogaster, GI18860063, Length=240, Percent_Identity=39.5833333333333, Blast_Score=184, Evalue=2e-46,
Organism=Drosophila melanogaster, GI281361487, Length=240, Percent_Identity=38.75, Blast_Score=183, Evalue=4e-46,
Organism=Drosophila melanogaster, GI24652279, Length=191, Percent_Identity=47.1204188481675, Blast_Score=182, Evalue=6e-46,
Organism=Drosophila melanogaster, GI19921202, Length=250, Percent_Identity=37.2, Blast_Score=178, Evalue=1e-44,
Organism=Drosophila melanogaster, GI24656820, Length=248, Percent_Identity=36.2903225806452, Blast_Score=160, Evalue=4e-39,
Organism=Drosophila melanogaster, GI24656825, Length=248, Percent_Identity=36.2903225806452, Blast_Score=159, Evalue=5e-39,
Organism=Drosophila melanogaster, GI281363136, Length=276, Percent_Identity=33.695652173913, Blast_Score=156, Evalue=4e-38,
Organism=Drosophila melanogaster, GI78707192, Length=276, Percent_Identity=33.695652173913, Blast_Score=156, Evalue=4e-38,
Organism=Drosophila melanogaster, GI18859657, Length=232, Percent_Identity=39.6551724137931, Blast_Score=149, Evalue=5e-36,
Organism=Drosophila melanogaster, GI24644145, Length=273, Percent_Identity=35.8974358974359, Blast_Score=149, Evalue=7e-36,
Organism=Drosophila melanogaster, GI281360144, Length=250, Percent_Identity=36, Blast_Score=149, Evalue=9e-36,
Organism=Drosophila melanogaster, GI281360140, Length=250, Percent_Identity=36, Blast_Score=149, Evalue=9e-36,
Organism=Drosophila melanogaster, GI281360136, Length=250, Percent_Identity=36, Blast_Score=148, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24644411, Length=250, Percent_Identity=36, Blast_Score=148, Evalue=1e-35,
Organism=Drosophila melanogaster, GI281360146, Length=250, Percent_Identity=36, Blast_Score=148, Evalue=1e-35,
Organism=Drosophila melanogaster, GI281360138, Length=250, Percent_Identity=36, Blast_Score=148, Evalue=1e-35,
Organism=Drosophila melanogaster, GI281360142, Length=250, Percent_Identity=36, Blast_Score=148, Evalue=1e-35,
Organism=Drosophila melanogaster, GI21357333, Length=250, Percent_Identity=36, Blast_Score=148, Evalue=1e-35,
Organism=Drosophila melanogaster, GI21355121, Length=207, Percent_Identity=36.7149758454106, Blast_Score=145, Evalue=1e-34,
Organism=Drosophila melanogaster, GI20129423, Length=234, Percent_Identity=36.7521367521368, Blast_Score=138, Evalue=1e-32,
Organism=Drosophila melanogaster, GI20129529, Length=240, Percent_Identity=35.4166666666667, Blast_Score=133, Evalue=4e-31,
Organism=Drosophila melanogaster, GI24581396, Length=265, Percent_Identity=35.4716981132075, Blast_Score=128, Evalue=1e-29,
Organism=Drosophila melanogaster, GI28571849, Length=263, Percent_Identity=36.8821292775665, Blast_Score=125, Evalue=9e-29,
Organism=Drosophila melanogaster, GI28571847, Length=263, Percent_Identity=36.8821292775665, Blast_Score=125, Evalue=9e-29,
Organism=Drosophila melanogaster, GI28573010, Length=247, Percent_Identity=34.8178137651822, Blast_Score=122, Evalue=9e-28,
Organism=Drosophila melanogaster, GI17864540, Length=255, Percent_Identity=34.5098039215686, Blast_Score=120, Evalue=4e-27,
Organism=Drosophila melanogaster, GI24639486, Length=281, Percent_Identity=28.8256227758007, Blast_Score=95, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FTSH_RALPJ (B2UE66)

Other databases:

- EMBL:   CP001068
- RefSeq:   YP_001899272.1
- ProteinModelPortal:   B2UE66
- GeneID:   6288683
- GenomeReviews:   CP001068_GR
- KEGG:   rpi:Rpic_1702
- HOGENOM:   HBG724153
- OMA:   MNPKEKE
- ProtClustDB:   CLSK716157
- GO:   GO:0006508
- HAMAP:   MF_01458
- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR003960
- InterPro:   IPR005936
- InterPro:   IPR000642
- SMART:   SM00382
- TIGRFAMs:   TIGR01241

Pfam domain/function: PF00004 AAA; PF01434 Peptidase_M41

EC number: 3.4.24.- [C]

Molecular weight: Translated: 78413; Mature: 78413

Theoretical pI: Translated: 7.74; Mature: 7.74

Prosite motif: PS00674 AAA

Important sites: ACT_SITE 503-503

Signals:

None

Transmembrane regions:

HASH(0x15d1679c)-; HASH(0x132917d4)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKPRRLRPRARPQCRGLMKVNLGDFQASILGTHTNARLSGAYPGRPPTFPALETRLTFN
CCCCCCCCCCCCHHHCCEEEECCCCHHHHHEECCCCCEECCCCCCCCCCCCCHHHEEEEE
KVDLEKNPMEPRQQQFSLWYVLVTILAMLAIQTLFVSGHVETIPYSDFKVLLKAGKLKDV
EECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCHH
AIGEQAISGTFSTEGIDNLLAKQQIEEIRREAKGDHAFSTLRVADPELVQELEAAKVRFV
HHCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHEEECCCHHHHHHHHHHHEEEE
GQPDNKWLSTILSWVVPAVIFFGIWSFLIKRVGGAAGSMMEIGKSKAKVYMQKETGVTFA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHEEEEECCCCCCHH
DVAGIDEAKEELSEIVSFLKDPQRYQRLGGKIPKGVLLVGAPGTGKTLLAKAVAGEAGVP
HHCCCHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHCCCCCCC
FFSMSGSDFVEMFVGVGAARVRDLFKQAETKAPCIIFIDELDALGKTRALNAVGGNEERE
EEECCCHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEECCHHHCCCHHEECCCCCCHHHH
QTLNQLLVEMDGFDSNKGVIIMAATNRPEILDPALLRPGRFDRHVALDRPDLKGREQILK
HHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHCCCCCCCCCEECCCCCCCHHHHHHH
VHVKGVVLAPEVDLTKLAGRTPGFAGADLANLVNEAALLAARKSKQMVEMADFDEALDRI
HHCCEEEECCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGGLEKKNRVMNPKEKETIAFHEAGHAIVAEHRPLADRVSKVSIIPRGVAALGYTQQTPT
HCCHHHHCCCCCCCHHHEEEEHHCCCEEEECCCCHHHHHHHHHHCCCCHHHHCCCCCCCC
EDRYLLKRSELLDRLDVLLGGRIAEQLIFGDVSTGAQNDLQRATDMARQMITQFGMSDQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
GLATYENMPNPLFAGTGLMQRERNEYSESTAQMIDAEVRKLLAEASHRVQATLEGQRTKL
CCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHCCCHHHH
DALAQLLLEKEVVDRQDLDMFLSAKVTPMPPPKPVANIEESTATGKPDQKTQGT
HHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
>Mature Secondary Structure
MEKPRRLRPRARPQCRGLMKVNLGDFQASILGTHTNARLSGAYPGRPPTFPALETRLTFN
CCCCCCCCCCCCHHHCCEEEECCCCHHHHHEECCCCCEECCCCCCCCCCCCCHHHEEEEE
KVDLEKNPMEPRQQQFSLWYVLVTILAMLAIQTLFVSGHVETIPYSDFKVLLKAGKLKDV
EECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCHH
AIGEQAISGTFSTEGIDNLLAKQQIEEIRREAKGDHAFSTLRVADPELVQELEAAKVRFV
HHCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHEEECCCHHHHHHHHHHHEEEE
GQPDNKWLSTILSWVVPAVIFFGIWSFLIKRVGGAAGSMMEIGKSKAKVYMQKETGVTFA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHEEEEECCCCCCHH
DVAGIDEAKEELSEIVSFLKDPQRYQRLGGKIPKGVLLVGAPGTGKTLLAKAVAGEAGVP
HHCCCHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHCCCCCCC
FFSMSGSDFVEMFVGVGAARVRDLFKQAETKAPCIIFIDELDALGKTRALNAVGGNEERE
EEECCCHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEECCHHHCCCHHEECCCCCCHHHH
QTLNQLLVEMDGFDSNKGVIIMAATNRPEILDPALLRPGRFDRHVALDRPDLKGREQILK
HHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHCCCCCCCCCEECCCCCCCHHHHHHH
VHVKGVVLAPEVDLTKLAGRTPGFAGADLANLVNEAALLAARKSKQMVEMADFDEALDRI
HHCCEEEECCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGGLEKKNRVMNPKEKETIAFHEAGHAIVAEHRPLADRVSKVSIIPRGVAALGYTQQTPT
HCCHHHHCCCCCCCHHHEEEEHHCCCEEEECCCCHHHHHHHHHHCCCCHHHHCCCCCCCC
EDRYLLKRSELLDRLDVLLGGRIAEQLIFGDVSTGAQNDLQRATDMARQMITQFGMSDQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
GLATYENMPNPLFAGTGLMQRERNEYSESTAQMIDAEVRKLLAEASHRVQATLEGQRTKL
CCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHCCCHHHH
DALAQLLLEKEVVDRQDLDMFLSAKVTPMPPPKPVANIEESTATGKPDQKTQGT
HHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Metalloendopeptidases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA