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The map label for this gene is apaH [H]

Identifier: 187927721

GI number: 187927721

Start: 665340

End: 666188

Strand: Reverse

Name: apaH [H]

Synonym: Rpic_0625

Alternate gene names: 187927721

Gene position: 666188-665340 (Counterclockwise)

Preceding gene: 187927722

Following gene: 187927713

Centisome position: 16.9

GC content: 63.96

Gene sequence:

>849_bases
ATGAATCGGGAATCTCCCCACGCCATCGGCGACCTCCAAGGCTGCTGCTCCCCACTCCAGACCCTGCTGGCCGCCCTCCC
AGCCAACGCCCCTCTCCGCTTCGTCGGCGATCTGATCAACCGTGGCCCCGACTCTCTCGCCACACTGCGCCAGGTCATTT
CCCTATGCGAAGCGGGACGCGCACGCACCGTTCTCGGCAACCATGACATCCACCTGCTGGCCGTGGCGGCAGGGGTGCGA
AAACCCGGCAAACGCGACACCATCGCCGAGATACTCTCTGCCCCCGATAGCGACCAACTCATCACTTGGCTGCGCCACCA
GCCGCTGGCCATCTTCGAAAACAGCTTTCTGATGGTGCACGCCGGCGTCCTGCCTCAATGGATAACAGGCGACGTACTCG
AGCTGGCCGGCGCAGTGGAGCGCGAGCTGCGTAGCCCACATTGGAAAACCTTCCTGGCCGATGCGTTTGGCAACCATCCC
GACAAGTGGAGTAACGATCTCGTCGGCATGGATCGGCTGCGGCTGACCATCAACGCCTTGACGCGCCTACGCTTCTGCAA
GCCCGATGGGACGATGGAGTTCGAGACGACTGACGCCGATGGCGCTCCGGATGGCCACATGCCGTGGTTCGACGTGCCAG
GGCGCCGTACGCGCGGCACGCCGATCGTGTTCGGGCATTGGTCCACACGCGGGCTGGTGATGCGCGACGATGTGATAGGC
CTGGATACCGGCTGCGTGTGGGGTGGCAAACTGACGGCGGCGAAGCTATCGTTGACGCCAGCCGGGCGTGACGTGATCCA
GGTGGATTGCGAGCAGGCGCAGGACCCGCTCGCGCACAAGAAGAAATAG

Upstream 100 bases:

>100_bases
TTTGCTATAGCCCTGATCAGGGAGCGCCAACAGACTCGTGCCGCATAAAATGCGTAAGGTCGATTTCTTCGCAATGATGG
CGTTTTGAGGGACATCTGTC

Downstream 100 bases:

>100_bases
CCGAGTAGCCTAGCCCGCGCGGTCGATCAGCGCGGCAACAGCGTCGTGACTATGTGCGGCCAGCCCACGGCGGTCCATCT
CCGGAGCTACGGCGGGGCCT

Product: diadenosine tetraphosphatase

Products: NA

Alternate protein names: Ap4A hydrolase; Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase; Diadenosine tetraphosphatase [H]

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MNRESPHAIGDLQGCCSPLQTLLAALPANAPLRFVGDLINRGPDSLATLRQVISLCEAGRARTVLGNHDIHLLAVAAGVR
KPGKRDTIAEILSAPDSDQLITWLRHQPLAIFENSFLMVHAGVLPQWITGDVLELAGAVERELRSPHWKTFLADAFGNHP
DKWSNDLVGMDRLRLTINALTRLRFCKPDGTMEFETTDADGAPDGHMPWFDVPGRRTRGTPIVFGHWSTRGLVMRDDVIG
LDTGCVWGGKLTAAKLSLTPAGRDVIQVDCEQAQDPLAHKKK

Sequences:

>Translated_282_residues
MNRESPHAIGDLQGCCSPLQTLLAALPANAPLRFVGDLINRGPDSLATLRQVISLCEAGRARTVLGNHDIHLLAVAAGVR
KPGKRDTIAEILSAPDSDQLITWLRHQPLAIFENSFLMVHAGVLPQWITGDVLELAGAVERELRSPHWKTFLADAFGNHP
DKWSNDLVGMDRLRLTINALTRLRFCKPDGTMEFETTDADGAPDGHMPWFDVPGRRTRGTPIVFGHWSTRGLVMRDDVIG
LDTGCVWGGKLTAAKLSLTPAGRDVIQVDCEQAQDPLAHKKK
>Mature_282_residues
MNRESPHAIGDLQGCCSPLQTLLAALPANAPLRFVGDLINRGPDSLATLRQVISLCEAGRARTVLGNHDIHLLAVAAGVR
KPGKRDTIAEILSAPDSDQLITWLRHQPLAIFENSFLMVHAGVLPQWITGDVLELAGAVERELRSPHWKTFLADAFGNHP
DKWSNDLVGMDRLRLTINALTRLRFCKPDGTMEFETTDADGAPDGHMPWFDVPGRRTRGTPIVFGHWSTRGLVMRDDVIG
LDTGCVWGGKLTAAKLSLTPAGRDVIQVDCEQAQDPLAHKKK

Specific function: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP [H]

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Ap4A hydrolase family [H]

Homologues:

Organism=Escherichia coli, GI1786234, Length=256, Percent_Identity=42.1875, Blast_Score=192, Evalue=1e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004617
- InterPro:   IPR004843 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: =3.6.1.41 [H]

Molecular weight: Translated: 30865; Mature: 30865

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRESPHAIGDLQGCCSPLQTLLAALPANAPLRFVGDLINRGPDSLATLRQVISLCEAGR
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
ARTVLGNHDIHLLAVAAGVRKPGKRDTIAEILSAPDSDQLITWLRHQPLAIFENSFLMVH
CEEEECCCCEEEEEEEHHCCCCCCHHHHHHHHCCCCCHHHHHHHHCCCCEEECCCEEEEE
AGVLPQWITGDVLELAGAVERELRSPHWKTFLADAFGNHPDKWSNDLVGMDRLRLTINAL
CCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
TRLRFCKPDGTMEFETTDADGAPDGHMPWFDVPGRRTRGTPIVFGHWSTRGLVMRDDVIG
HHHEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCEEEECCEEE
LDTGCVWGGKLTAAKLSLTPAGRDVIQVDCEQAQDPLAHKKK
CCCCCEECCCEEEEEEEECCCCCCEEEEEHHHHCCCCCCCCC
>Mature Secondary Structure
MNRESPHAIGDLQGCCSPLQTLLAALPANAPLRFVGDLINRGPDSLATLRQVISLCEAGR
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
ARTVLGNHDIHLLAVAAGVRKPGKRDTIAEILSAPDSDQLITWLRHQPLAIFENSFLMVH
CEEEECCCCEEEEEEEHHCCCCCCHHHHHHHHCCCCCHHHHHHHHCCCCEEECCCEEEEE
AGVLPQWITGDVLELAGAVERELRSPHWKTFLADAFGNHPDKWSNDLVGMDRLRLTINAL
CCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
TRLRFCKPDGTMEFETTDADGAPDGHMPWFDVPGRRTRGTPIVFGHWSTRGLVMRDDVIG
HHHEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCEEEECCEEE
LDTGCVWGGKLTAAKLSLTPAGRDVIQVDCEQAQDPLAHKKK
CCCCCEECCCEEEEEEEECCCCCCEEEEEHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]