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The map label for this gene is fabG [H]

Identifier: 187927657

GI number: 187927657

Start: 593755

End: 594462

Strand: Reverse

Name: fabG [H]

Synonym: Rpic_0560

Alternate gene names: 187927657

Gene position: 594462-593755 (Counterclockwise)

Preceding gene: 187927658

Following gene: 187927653

Centisome position: 15.08

GC content: 69.92

Gene sequence:

>708_bases
ATGCCAACCCGCCCCGCACCGCAAGCCGCTGCCGCCCGTCATGCCATCGTGACTGGCGCCTCCTCGGGCATCGGCCGCGC
CATTGCAGAGCGCCTGCTGGCCGACGGCTGGCGCGTGACAGGCCTGTGCCGGACCGCGCCCGCCGAGCCGGTCGAAGGGT
TGGAGATCGCACAGGTGGATGTGACGGACTTCGCGCGGTTGGGCAAGGTATGCGACAGCCTGGGCGCAGTTGACGCACTT
GTGCATGCTGCCGGCTTCATGCGCACAGCCCCATTGGGCGAGCTTTGCGCCGCCGATGGTGAGGCGATGTGGCGCGTGCA
CGTCGATGCCGCCGCCTTCCTCGCAGACAGACTCGTGCAGCGCATGCCGGCCGGCGGCCGCATTCTCTTGATCGGTAGCC
GCACGGCCAACGGCGCCCCAACGCGCAGCCAGTACGCCGCCACCAAGGCGGCCCTCGTGGGTATGGCGCGTTCGTGGGCC
GCCGAACTGGCGCCGCGCGGCATCACCGTCAACGTGATTGCGCCCGGCGCGACGGATACACCGTTCCTGCACGACCCTGC
ACGCGCGCACACCCCGCCGCGCATGCCGCCTATCGGCCGGTTCATCGCGCCCGAAGAAGTGGCCGCCATGGCGGCATTCC
TGGCAGGCGAATACGGCGGCGCCATCACCGGTCAGCAGATCGTGATGTGTGGTGGGGCGTCGTTGTAG

Upstream 100 bases:

>100_bases
CCTGGACGCTCATCACCGACAACGGTGCATCGCCCGATCAACTGGACCCATTCCACGAACGCGACGAGGTCGACGTGGAA
ATCGCCCCGCTGGACTAAGC

Downstream 100 bases:

>100_bases
CGCTGGCGTGCAGTTAGGAGATCACGCCAAAGCGGGGCAGATGCCCGGTGGCCTCGGCGAGCAATCAGCCTTGCCTTGCT
TGCATCGTGCGCGCGGCGGC

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 235; Mature: 234

Protein sequence:

>235_residues
MPTRPAPQAAAARHAIVTGASSGIGRAIAERLLADGWRVTGLCRTAPAEPVEGLEIAQVDVTDFARLGKVCDSLGAVDAL
VHAAGFMRTAPLGELCAADGEAMWRVHVDAAAFLADRLVQRMPAGGRILLIGSRTANGAPTRSQYAATKAALVGMARSWA
AELAPRGITVNVIAPGATDTPFLHDPARAHTPPRMPPIGRFIAPEEVAAMAAFLAGEYGGAITGQQIVMCGGASL

Sequences:

>Translated_235_residues
MPTRPAPQAAAARHAIVTGASSGIGRAIAERLLADGWRVTGLCRTAPAEPVEGLEIAQVDVTDFARLGKVCDSLGAVDAL
VHAAGFMRTAPLGELCAADGEAMWRVHVDAAAFLADRLVQRMPAGGRILLIGSRTANGAPTRSQYAATKAALVGMARSWA
AELAPRGITVNVIAPGATDTPFLHDPARAHTPPRMPPIGRFIAPEEVAAMAAFLAGEYGGAITGQQIVMCGGASL
>Mature_234_residues
PTRPAPQAAAARHAIVTGASSGIGRAIAERLLADGWRVTGLCRTAPAEPVEGLEIAQVDVTDFARLGKVCDSLGAVDALV
HAAGFMRTAPLGELCAADGEAMWRVHVDAAAFLADRLVQRMPAGGRILLIGSRTANGAPTRSQYAATKAALVGMARSWAA
ELAPRGITVNVIAPGATDTPFLHDPARAHTPPRMPPIGRFIAPEEVAAMAAFLAGEYGGAITGQQIVMCGGASL

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI66933014, Length=199, Percent_Identity=26.6331658291457, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI40254992, Length=236, Percent_Identity=32.6271186440678, Blast_Score=81, Evalue=7e-16,
Organism=Homo sapiens, GI32483357, Length=246, Percent_Identity=31.3008130081301, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI7705925, Length=237, Percent_Identity=30.8016877637131, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI5031737, Length=244, Percent_Identity=30.7377049180328, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI15277342, Length=245, Percent_Identity=29.3877551020408, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI33667109, Length=191, Percent_Identity=34.5549738219895, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI126723750, Length=242, Percent_Identity=27.2727272727273, Blast_Score=64, Evalue=9e-11,
Organism=Escherichia coli, GI1787335, Length=239, Percent_Identity=35.5648535564854, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI2367365, Length=224, Percent_Identity=36.6071428571429, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1786812, Length=244, Percent_Identity=32.7868852459016, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1788459, Length=244, Percent_Identity=32.3770491803279, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI87082100, Length=249, Percent_Identity=30.1204819277108, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1789378, Length=248, Percent_Identity=27.8225806451613, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789208, Length=240, Percent_Identity=26.25, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87082160, Length=241, Percent_Identity=29.4605809128631, Blast_Score=68, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17555706, Length=244, Percent_Identity=29.0983606557377, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI25147288, Length=259, Percent_Identity=25.4826254826255, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17562910, Length=256, Percent_Identity=30.46875, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562906, Length=271, Percent_Identity=29.520295202952, Blast_Score=71, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24643142, Length=240, Percent_Identity=27.9166666666667, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21355319, Length=247, Percent_Identity=31.9838056680162, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24639444, Length=242, Percent_Identity=29.7520661157025, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24641232, Length=210, Percent_Identity=29.5238095238095, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 24163; Mature: 24032

Theoretical pI: Translated: 7.99; Mature: 7.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTRPAPQAAAARHAIVTGASSGIGRAIAERLLADGWRVTGLCRTAPAEPVEGLEIAQVD
CCCCCCCHHHHHHHHHEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEEEEC
VTDFARLGKVCDSLGAVDALVHAAGFMRTAPLGELCAADGEAMWRVHVDAAAFLADRLVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCEEEEEEHHHHHHHHHHHHH
RMPAGGRILLIGSRTANGAPTRSQYAATKAALVGMARSWAAELAPRGITVNVIAPGATDT
HCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCC
PFLHDPARAHTPPRMPPIGRFIAPEEVAAMAAFLAGEYGGAITGQQIVMCGGASL
CCCCCCHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCC
>Mature Secondary Structure 
PTRPAPQAAAARHAIVTGASSGIGRAIAERLLADGWRVTGLCRTAPAEPVEGLEIAQVD
CCCCCCHHHHHHHHHEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEEEEC
VTDFARLGKVCDSLGAVDALVHAAGFMRTAPLGELCAADGEAMWRVHVDAAAFLADRLVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCEEEEEEHHHHHHHHHHHHH
RMPAGGRILLIGSRTANGAPTRSQYAATKAALVGMARSWAAELAPRGITVNVIAPGATDT
HCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCC
PFLHDPARAHTPPRMPPIGRFIAPEEVAAMAAFLAGEYGGAITGQQIVMCGGASL
CCCCCCHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12522265 [H]