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The map label for this gene is qseD [H]

Identifier: 187927530

GI number: 187927530

Start: 458095

End: 459018

Strand: Direct

Name: qseD [H]

Synonym: Rpic_0428

Alternate gene names: 187927530

Gene position: 458095-459018 (Clockwise)

Preceding gene: 187927527

Following gene: 187927531

Centisome position: 11.62

GC content: 67.53

Gene sequence:

>924_bases
ATGCAGATCAAATGGCTGGAAGACTTCAAGGAACTGGCCAAGACGCGCAGCTTCAGCCGCGCCGCCGAGAACCGCAACGT
CACGCACCCCGCATTCGGCCGCCGGATCAAGGCCCTGGAGGAATGGGTGGGCACCGCACTGGTCGAGCGCAGCGAGCATC
CCGTCACGCTTACCGCGGCAGGGCGCTTGTTTCTGGATGCGGCCGCCAATGCCGTCGACGGCCTGAACGATGCGCGCTTG
CTGCTGCGGGAGGCGCAACTGCCCGTGGCGCTCAGGATCGGTACCGGGCGCACGCTGGCGCGCACGTTCGTCCCCGGCTG
GTACGAAACGCTGGCGCGTCAGCGCGGTGTGTTTCCGCTCAGCGTGACGACGGGTGGCACGCAGGAAGGCGTGCTGGCCC
TTGCCGATGGCACGGTCGATTTGCTGATCGCCTACGCCAGCCCACAGGCCGATGCGCTGCTCGATCCGCGCAAGTACGAC
CATTGCCTGCTGGGCAGCGAGACGCTCGTGCCGGTGAGCGCCCCCGACAAGCGCGGCCGCCCGCGCTTCACGCTGCCGGG
CTCGGCTGCCGCACCGCTTCCATGGCTGGCCTTCGCGCGTGGGCTGACATTGCGGCAGATGCTCGACAGCCATCTGGCTG
CCGCCGATCGGAAGGCGCATCTGCAGCCCGTGTTCCAGGCGGATTTTTACGAAGCGGTGGAAGAGATGGCCCTGCGCGGA
TTCGGCATGGCGTGGCTGCCGTATCGCCTGGCCAGGCCGCACCTGAACGCGGGTGAACTGCGCCCCGCTGGTGACGACGC
CTGGCACATCCACGTCAACATCCGCATGATGCGCGTGCGTAGCAACCAGAGCGCGCTGCTCGACGAGGTGTGGCAACGGG
CGGTCGACAACGCCAGCGGTAACGGCCGTAACGATCTCACCTGA

Upstream 100 bases:

>100_bases
CTCAAGATGATAACGATACGGCACGCACGTTAAGGCTGTTCGCGCAGGCTGCGGAGATAATGCGCAGACCTCACGCCCAC
CACAAAAGACCGGACGCGCC

Downstream 100 bases:

>100_bases
GGCGCGTCGCAAAAAGCCCAACCTTGTGCCGAAACGGCACAAGCCGCCTCGGCGCGGCACCTAGACTCCTCCGCAACCTT
CGCCCGCCAGCGCCGTTCGG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Quorum-sensing regulator protein D [H]

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MQIKWLEDFKELAKTRSFSRAAENRNVTHPAFGRRIKALEEWVGTALVERSEHPVTLTAAGRLFLDAAANAVDGLNDARL
LLREAQLPVALRIGTGRTLARTFVPGWYETLARQRGVFPLSVTTGGTQEGVLALADGTVDLLIAYASPQADALLDPRKYD
HCLLGSETLVPVSAPDKRGRPRFTLPGSAAAPLPWLAFARGLTLRQMLDSHLAAADRKAHLQPVFQADFYEAVEEMALRG
FGMAWLPYRLARPHLNAGELRPAGDDAWHIHVNIRMMRVRSNQSALLDEVWQRAVDNASGNGRNDLT

Sequences:

>Translated_307_residues
MQIKWLEDFKELAKTRSFSRAAENRNVTHPAFGRRIKALEEWVGTALVERSEHPVTLTAAGRLFLDAAANAVDGLNDARL
LLREAQLPVALRIGTGRTLARTFVPGWYETLARQRGVFPLSVTTGGTQEGVLALADGTVDLLIAYASPQADALLDPRKYD
HCLLGSETLVPVSAPDKRGRPRFTLPGSAAAPLPWLAFARGLTLRQMLDSHLAAADRKAHLQPVFQADFYEAVEEMALRG
FGMAWLPYRLARPHLNAGELRPAGDDAWHIHVNIRMMRVRSNQSALLDEVWQRAVDNASGNGRNDLT
>Mature_307_residues
MQIKWLEDFKELAKTRSFSRAAENRNVTHPAFGRRIKALEEWVGTALVERSEHPVTLTAAGRLFLDAAANAVDGLNDARL
LLREAQLPVALRIGTGRTLARTFVPGWYETLARQRGVFPLSVTTGGTQEGVLALADGTVDLLIAYASPQADALLDPRKYD
HCLLGSETLVPVSAPDKRGRPRFTLPGSAAAPLPWLAFARGLTLRQMLDSHLAAADRKAHLQPVFQADFYEAVEEMALRG
FGMAWLPYRLARPHLNAGELRPAGDDAWHIHVNIRMMRVRSNQSALLDEVWQRAVDNASGNGRNDLT

Specific function: Down-regulates expression of the flagellar regulon, decreasing motility [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790783, Length=296, Percent_Identity=27.027027027027, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1787879, Length=273, Percent_Identity=26.007326007326, Blast_Score=71, Evalue=8e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33886; Mature: 33886

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIKWLEDFKELAKTRSFSRAAENRNVTHPAFGRRIKALEEWVGTALVERSEHPVTLTAA
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
GRLFLDAAANAVDGLNDARLLLREAQLPVALRIGTGRTLARTFVPGWYETLARQRGVFPL
CHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEECCCCHHHHHHCCHHHHHHHHHCCCEEE
SVTTGGTQEGVLALADGTVDLLIAYASPQADALLDPRKYDHCLLGSETLVPVSAPDKRGR
EEECCCCCCCEEEEECCCEEEEEEECCCCCCCCCCCCCCCCEEECCCEEEECCCCCCCCC
PRFTLPGSAAAPLPWLAFARGLTLRQMLDSHLAAADRKAHLQPVFQADFYEAVEEMALRG
CCEECCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHC
FGMAWLPYRLARPHLNAGELRPAGDDAWHIHVNIRMMRVRSNQSALLDEVWQRAVDNASG
CCCHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEEEEEEECCCCHHHHHHHHHHHHCCCCC
NGRNDLT
CCCCCCC
>Mature Secondary Structure
MQIKWLEDFKELAKTRSFSRAAENRNVTHPAFGRRIKALEEWVGTALVERSEHPVTLTAA
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
GRLFLDAAANAVDGLNDARLLLREAQLPVALRIGTGRTLARTFVPGWYETLARQRGVFPL
CHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEECCCCHHHHHHCCHHHHHHHHHCCCEEE
SVTTGGTQEGVLALADGTVDLLIAYASPQADALLDPRKYDHCLLGSETLVPVSAPDKRGR
EEECCCCCCCEEEEECCCEEEEEEECCCCCCCCCCCCCCCCEEECCCEEEECCCCCCCCC
PRFTLPGSAAAPLPWLAFARGLTLRQMLDSHLAAADRKAHLQPVFQADFYEAVEEMALRG
CCEECCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHC
FGMAWLPYRLARPHLNAGELRPAGDDAWHIHVNIRMMRVRSNQSALLDEVWQRAVDNASG
CCCHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEEEEEEECCCCHHHHHHHHHHHHCCCCC
NGRNDLT
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 7876157 [H]