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The map label for this gene is fabG [H]

Identifier: 187927519

GI number: 187927519

Start: 443981

End: 445393

Strand: Reverse

Name: fabG [H]

Synonym: Rpic_0416

Alternate gene names: 187927519

Gene position: 445393-443981 (Counterclockwise)

Preceding gene: 187927520

Following gene: 187927518

Centisome position: 11.3

GC content: 67.94

Gene sequence:

>1413_bases
ATGCAAGACAAGTACCTCGATTTCGTCGGTTCCGGTTTCGGCAAGTGGCTGTCGGCCAACCTCGGCCTGCCGCAGCCTGT
GCCGTTGCGCCGTTATGTGCCCGGCGAACCGGAATTTGTCGGGCCGTTCCTGGTGGGCGCGGCGCCGGGCGGCTCCATGC
GCGAAACGCTCGCCGCACTGTTTGCCGAGACCGGCGTCCCTACGCGCTTTCATGAAAGCGATCCGGAATGGCTTGGTGCC
GCCAACCGGCACGGCCAGATCACGGGCCGCTTTGTCGCCCCGACGGGCAAGGACGGCGAGGCGTTTGATCGCATTGGCGG
CATCGTCTTCGATGCCACGGGCATTGCGACGGTCGACGGCCTCGACGCGCTGTATCACGTGTTCCACGATGGCGTGCGGG
CCATCGGCCGTTGTGGGCGCGTCGTGGTGATCGGCCGGCCGCCGGAAGGTTGCAAGACGCCCGAGATGGCGATTGCGCAG
CGCGCGCTGGAAGGGCTGACGCGCTCTCTTGGCAAGGAAGTCCGGCGCGGCTGCACGGCGCAGCTCGTCTACGTGGCTGA
GGGAGCGGAGAACGTGGCCGTATCGACGCTGCGCTTTCTGCTGTCGGCACGCTCGGCGTATGTGTCGGGGCAGGTGGTGC
GCGTGCATCGGGCGGCAGCGGTCTCGGTGGACTGGCAGAAGCCGCTGGCCGGGCGCACCGCGTTGGTGACCGGCGCCTCG
CGCGGCATCGGCGCGGCCATTGCGCACGTGCTGGCACGTGACGGTGCGCGCGTACTTTGCCTGGATGTGCCCGCCGCGCA
GGAAGCGCTGAACGCGGTCGCGCAGGAAATCGGCGGTGAGGCCATGGCCTACGACATTGCTGCGCCCGAGACACCCGCCC
TGCTCGCGCAGCAACTTGCTGCATTGGGCGGCATCGACATCCTCGTGCACAACGCCGGCATCACGCGCGACAAGACCATC
GCCCGCATGACCGAGCCCGCTTGGCGCAGCGTGCTCGATATCAACCTCGCCGCGCAGTTGCGCATCAACGACGCGCTGCT
TGCGGCCAATGCGCTGCACGCAGGCGGGTCCATCGTGTGCGTGTCGTCCATCAGCGGCATTGCAGGCAACCTTGGGCAGA
CCAACTACGCGATGTCCAAGGCCGGCGTGATCGGGCTCGTGCAAGCAGGCGCACCGTTGCTGGCAGAGCGCGGCATCACC
ATCAACGCTGTCGCGCCGGGCTTTATCGAGACGCAGATGACAGCGGCCGTGCCGTTTGCCATCCGCGAAGCCGGCCGCCG
CATGAACGCGATGAGCCAGGGCGGCCAGCCCGTCGACGTGGCCGAGACGATCGCGTGGTTCGCCAACCCGGCGTCCAACG
GCGTGACGGGCAACATCGTGCGCGTGTGCGGGCAAAGCCTGCTGGGAGCCTGA

Upstream 100 bases:

>100_bases
GCCGACCTGCAGCGCCGCAAGGATGCGCTCGATGCCCTGCAGGCCGCCGAGCGCCGCGCAGCCTGATGGCCCAGGGGCCT
GACAAACGACAACAACAACG

Downstream 100 bases:

>100_bases
CGCGACCATGCGCACGCTGGCCCAGCCCTTTCCGATGGTCGCAACCCAGACGCTGGTAACCGAGCCGCCGTCGCCGGGGG
CACTGGCCTGGCGCGCGCTG

Product: 3-ketoacyl-(acyl-carrier-protein) reductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MQDKYLDFVGSGFGKWLSANLGLPQPVPLRRYVPGEPEFVGPFLVGAAPGGSMRETLAALFAETGVPTRFHESDPEWLGA
ANRHGQITGRFVAPTGKDGEAFDRIGGIVFDATGIATVDGLDALYHVFHDGVRAIGRCGRVVVIGRPPEGCKTPEMAIAQ
RALEGLTRSLGKEVRRGCTAQLVYVAEGAENVAVSTLRFLLSARSAYVSGQVVRVHRAAAVSVDWQKPLAGRTALVTGAS
RGIGAAIAHVLARDGARVLCLDVPAAQEALNAVAQEIGGEAMAYDIAAPETPALLAQQLAALGGIDILVHNAGITRDKTI
ARMTEPAWRSVLDINLAAQLRINDALLAANALHAGGSIVCVSSISGIAGNLGQTNYAMSKAGVIGLVQAGAPLLAERGIT
INAVAPGFIETQMTAAVPFAIREAGRRMNAMSQGGQPVDVAETIAWFANPASNGVTGNIVRVCGQSLLGA

Sequences:

>Translated_470_residues
MQDKYLDFVGSGFGKWLSANLGLPQPVPLRRYVPGEPEFVGPFLVGAAPGGSMRETLAALFAETGVPTRFHESDPEWLGA
ANRHGQITGRFVAPTGKDGEAFDRIGGIVFDATGIATVDGLDALYHVFHDGVRAIGRCGRVVVIGRPPEGCKTPEMAIAQ
RALEGLTRSLGKEVRRGCTAQLVYVAEGAENVAVSTLRFLLSARSAYVSGQVVRVHRAAAVSVDWQKPLAGRTALVTGAS
RGIGAAIAHVLARDGARVLCLDVPAAQEALNAVAQEIGGEAMAYDIAAPETPALLAQQLAALGGIDILVHNAGITRDKTI
ARMTEPAWRSVLDINLAAQLRINDALLAANALHAGGSIVCVSSISGIAGNLGQTNYAMSKAGVIGLVQAGAPLLAERGIT
INAVAPGFIETQMTAAVPFAIREAGRRMNAMSQGGQPVDVAETIAWFANPASNGVTGNIVRVCGQSLLGA
>Mature_470_residues
MQDKYLDFVGSGFGKWLSANLGLPQPVPLRRYVPGEPEFVGPFLVGAAPGGSMRETLAALFAETGVPTRFHESDPEWLGA
ANRHGQITGRFVAPTGKDGEAFDRIGGIVFDATGIATVDGLDALYHVFHDGVRAIGRCGRVVVIGRPPEGCKTPEMAIAQ
RALEGLTRSLGKEVRRGCTAQLVYVAEGAENVAVSTLRFLLSARSAYVSGQVVRVHRAAAVSVDWQKPLAGRTALVTGAS
RGIGAAIAHVLARDGARVLCLDVPAAQEALNAVAQEIGGEAMAYDIAAPETPALLAQQLAALGGIDILVHNAGITRDKTI
ARMTEPAWRSVLDINLAAQLRINDALLAANALHAGGSIVCVSSISGIAGNLGQTNYAMSKAGVIGLVQAGAPLLAERGIT
INAVAPGFIETQMTAAVPFAIREAGRRMNAMSQGGQPVDVAETIAWFANPASNGVTGNIVRVCGQSLLGA

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=254, Percent_Identity=39.7637795275591, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI40254992, Length=232, Percent_Identity=33.1896551724138, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI32483357, Length=258, Percent_Identity=31.7829457364341, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI4504505, Length=186, Percent_Identity=34.9462365591398, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI5031737, Length=264, Percent_Identity=28.030303030303, Blast_Score=86, Evalue=8e-17,
Organism=Homo sapiens, GI126723191, Length=195, Percent_Identity=32.3076923076923, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI33667109, Length=213, Percent_Identity=30.9859154929577, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI40807363, Length=196, Percent_Identity=29.5918367346939, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI126723750, Length=262, Percent_Identity=27.0992366412214, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI7657478, Length=241, Percent_Identity=28.2157676348548, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI31542939, Length=231, Percent_Identity=28.1385281385281, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI19923817, Length=257, Percent_Identity=27.6264591439689, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI1787335, Length=237, Percent_Identity=37.5527426160338, Blast_Score=144, Evalue=2e-35,
Organism=Escherichia coli, GI87082100, Length=255, Percent_Identity=31.7647058823529, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1789208, Length=244, Percent_Identity=29.5081967213115, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI2367365, Length=237, Percent_Identity=32.9113924050633, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1790717, Length=246, Percent_Identity=28.4552845528455, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI87082160, Length=263, Percent_Identity=26.615969581749, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1787905, Length=243, Percent_Identity=32.5102880658436, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI2367175, Length=253, Percent_Identity=34.3873517786561, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1789378, Length=251, Percent_Identity=31.0756972111554, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1789057, Length=259, Percent_Identity=28.5714285714286, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1786812, Length=253, Percent_Identity=27.2727272727273, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1787526, Length=242, Percent_Identity=30.1652892561983, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1788459, Length=245, Percent_Identity=25.3061224489796, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI25147288, Length=240, Percent_Identity=37.5, Blast_Score=146, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI17555706, Length=240, Percent_Identity=37.5, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17561402, Length=248, Percent_Identity=29.0322580645161, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17568967, Length=186, Percent_Identity=31.7204301075269, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71994604, Length=246, Percent_Identity=30.0813008130081, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17562908, Length=241, Percent_Identity=31.5352697095436, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17538182, Length=205, Percent_Identity=30.2439024390244, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17560676, Length=246, Percent_Identity=26.8292682926829, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17564282, Length=214, Percent_Identity=30.8411214953271, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71994600, Length=245, Percent_Identity=27.3469387755102, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17562906, Length=243, Percent_Identity=32.0987654320988, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17508895, Length=206, Percent_Identity=28.6407766990291, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17567345, Length=220, Percent_Identity=27.7272727272727, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17559104, Length=262, Percent_Identity=27.4809160305344, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17531453, Length=245, Percent_Identity=31.0204081632653, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193204405, Length=266, Percent_Identity=29.6992481203008, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17560220, Length=264, Percent_Identity=27.6515151515151, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193203117, Length=210, Percent_Identity=27.1428571428571, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193203115, Length=198, Percent_Identity=27.7777777777778, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17562910, Length=261, Percent_Identity=26.8199233716475, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17560150, Length=250, Percent_Identity=27.6, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=210, Percent_Identity=30.952380952381, Blast_Score=93, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24639444, Length=245, Percent_Identity=36.734693877551, Blast_Score=138, Evalue=1e-32,
Organism=Drosophila melanogaster, GI18859837, Length=195, Percent_Identity=34.8717948717949, Blast_Score=101, Evalue=9e-22,
Organism=Drosophila melanogaster, GI23397609, Length=247, Percent_Identity=31.5789473684211, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI17737361, Length=249, Percent_Identity=30.5220883534137, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24644339, Length=243, Percent_Identity=32.0987654320988, Blast_Score=85, Evalue=9e-17,
Organism=Drosophila melanogaster, GI21355319, Length=203, Percent_Identity=33.4975369458128, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21357041, Length=241, Percent_Identity=31.1203319502075, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI21358495, Length=233, Percent_Identity=27.4678111587983, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24643142, Length=187, Percent_Identity=32.0855614973262, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI28571526, Length=239, Percent_Identity=30.9623430962343, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281364892, Length=169, Percent_Identity=28.9940828402367, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24640492, Length=191, Percent_Identity=29.8429319371728, Blast_Score=69, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 48787; Mature: 48787

Theoretical pI: Translated: 7.53; Mature: 7.53

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDKYLDFVGSGFGKWLSANLGLPQPVPLRRYVPGEPEFVGPFLVGAAPGGSMRETLAAL
CCCCHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCCCCEECCEEEECCCCCHHHHHHHHH
FAETGVPTRFHESDPEWLGAANRHGQITGRFVAPTGKDGEAFDRIGGIVFDATGIATVDG
HHHCCCCCCCCCCCHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHCCEEEECCCCCCHHH
LDALYHVFHDGVRAIGRCGRVVVIGRPPEGCKTPEMAIAQRALEGLTRSLGKEVRRGCTA
HHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCE
QLVYVAEGAENVAVSTLRFLLSARSAYVSGQVVRVHRAAAVSVDWQKPLAGRTALVTGAS
EEEEEECCCCHHHHHHHHHHHHHHHHHHCCEEEEEEEEEEEEECCCCCCCCCEEEEECCC
RGIGAAIAHVLARDGARVLCLDVPAAQEALNAVAQEIGGEAMAYDIAAPETPALLAQQLA
CCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHH
ALGGIDILVHNAGITRDKTIARMTEPAWRSVLDINLAAQLRINDALLAANALHAGGSIVC
HHCCEEEEEECCCCCCCHHHHHHCCHHHHHHHEECEEEEEEECHHHHHHHHHCCCCCEEE
VSSISGIAGNLGQTNYAMSKAGVIGLVQAGAPLLAERGITINAVAPGFIETQMTAAVPFA
EECCCCHHCCCCCCHHHHHHCCEEEEECCCCCHHHHCCCEEEECCCCHHHHHHHHHHHHH
IREAGRRMNAMSQGGQPVDVAETIAWFANPASNGVTGNIVRVCGQSLLGA
HHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MQDKYLDFVGSGFGKWLSANLGLPQPVPLRRYVPGEPEFVGPFLVGAAPGGSMRETLAAL
CCCCHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCCCCEECCEEEECCCCCHHHHHHHHH
FAETGVPTRFHESDPEWLGAANRHGQITGRFVAPTGKDGEAFDRIGGIVFDATGIATVDG
HHHCCCCCCCCCCCHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHCCEEEECCCCCCHHH
LDALYHVFHDGVRAIGRCGRVVVIGRPPEGCKTPEMAIAQRALEGLTRSLGKEVRRGCTA
HHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCE
QLVYVAEGAENVAVSTLRFLLSARSAYVSGQVVRVHRAAAVSVDWQKPLAGRTALVTGAS
EEEEEECCCCHHHHHHHHHHHHHHHHHHCCEEEEEEEEEEEEECCCCCCCCCEEEEECCC
RGIGAAIAHVLARDGARVLCLDVPAAQEALNAVAQEIGGEAMAYDIAAPETPALLAQQLA
CCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHH
ALGGIDILVHNAGITRDKTIARMTEPAWRSVLDINLAAQLRINDALLAANALHAGGSIVC
HHCCEEEEEECCCCCCCHHHHHHCCHHHHHHHEECEEEEEEECHHHHHHHHHCCCCCEEE
VSSISGIAGNLGQTNYAMSKAGVIGLVQAGAPLLAERGITINAVAPGFIETQMTAAVPFA
EECCCCHHCCCCCCHHHHHHCCEEEEECCCCCHHHHCCCEEEECCCCHHHHHHHHHHHHH
IREAGRRMNAMSQGGQPVDVAETIAWFANPASNGVTGNIVRVCGQSLLGA
HHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]