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The map label for this gene is ubiH [H]

Identifier: 187927487

GI number: 187927487

Start: 407205

End: 408440

Strand: Reverse

Name: ubiH [H]

Synonym: Rpic_0384

Alternate gene names: 187927487

Gene position: 408440-407205 (Counterclockwise)

Preceding gene: 187927488

Following gene: 187927486

Centisome position: 10.36

GC content: 71.52

Gene sequence:

>1236_bases
ATGACCGACAGCATCACAGCGAGCAGCGCCGCACCGGACTTCGACGTGGCCATCGTTGGCGCCGGGCCCGTCGGGCTGGC
GCTGGCCAACTGGTTGCTGCGCGACACCGACTGGCGCATCGCCCTGTTCGATGCGCGCGACGCCGAAGCCGCCGCGCGAG
ACCCGCGCGCGCTGGCGCTGTCTCATGGCTCGCGCGTGCTGCTGCAGGAGATTGGCGGCTGGCCCACGCGCGCCACGCCC
ATCACGCACATCCACGTCTCGCAACGCGGCCACTTCGGGCAGGCGCATATCCGCCGTGAAGACTACGACGTCCCCGCGCT
CGGACACGTCGTGCAATACGGCGACCTGAGCGCCGCGCTCAACGCCGCCCTCGACACGCAGATGGAGCGTCACCCGGGGC
GCCTCACCCGCTATGACCACACGCCCGTGGAGCGCGTCGAACAACTGCCGCGCGCCGACGGTACGGTCGCCCCGGCACGC
GTGCGGGCGCTGCGCGAAGGGCGCCATCCGCTGGCCATCGAAACCGAAGTCGTCATCCAGGCCGAAGGCGGGTTGTTCGA
CGACGCACGCAAGCAGCAACGCGGCATCGCCCAGGCGCGCCGGCGCGATTACGGCCAGACCGCCATCGTCGCGCACGTGC
GCTGCAGCGCCCCGCTCGAAGGCTGGGCATGGGAGCGTTTCACGCCCGAAGGCCCGCTCGCATTGCTGCCGCAGGATGAC
GCGCAAGGTCCCGGCTACGCCCTTGTCTGGTGCTGCGCGCCCGACGAAGCGCGCCGACGCGCAGCGTTGCCCGACGACGC
CTTCCTCGCCGAACTGGGCGCTGCCTTTGGCGAGCGCATGGGCCGCTTCACGCACGCCAGCCCGCGCCATACGTTCGCGC
TCGGGCTGCACGCCCAGCGCATTCCGGTCGACCGCCGCGTCGCCGCCATCGGCAATGCCGCCCAGACGATCCACCCGGTG
GCGGGCCAGGGCTTCAACCTCGGCCTGCGCGATGCGTTCGAAATGGCACGCGCGCTTCGGGATGGGGCAACGGCGGCCAC
CCTCGCCCGTTTCGCCCGCGAACGCGCATTTGACCGCGCCGTCACCATCGGCCTGACCGATTTGCTGCCGCGCGCGTTTG
CCGTGCCGGGCCGGTCGTTTGGCCACCTGCGCGGCGCCGCGCTCACGCTGCTGGAATGCCTGCCGCCGCTCAAGCATGGG
CTCGCCCGGCAGATGATGTTCGGGCAGCGAGGCTAA

Upstream 100 bases:

>100_bases
TTGAAGACGACGCCATCGTCACGCCCGAAGGCTGCGAAATCATCACGCGCGACGTGCCCGTAGCCCCGGACGAAATCGAA
CTGGTGATGCGGGGCCAGGC

Downstream 100 bases:

>100_bases
CGGATGGCGTGTGCCGAGGTAGGCGCTGCAGGCGACCGCCAGCAGATCACCGTGGTGGGCGCCGGCATTGTCGGCACGGC
GTGCGCACTGCAATTGCAAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 411; Mature: 410

Protein sequence:

>411_residues
MTDSITASSAAPDFDVAIVGAGPVGLALANWLLRDTDWRIALFDARDAEAAARDPRALALSHGSRVLLQEIGGWPTRATP
ITHIHVSQRGHFGQAHIRREDYDVPALGHVVQYGDLSAALNAALDTQMERHPGRLTRYDHTPVERVEQLPRADGTVAPAR
VRALREGRHPLAIETEVVIQAEGGLFDDARKQQRGIAQARRRDYGQTAIVAHVRCSAPLEGWAWERFTPEGPLALLPQDD
AQGPGYALVWCCAPDEARRRAALPDDAFLAELGAAFGERMGRFTHASPRHTFALGLHAQRIPVDRRVAAIGNAAQTIHPV
AGQGFNLGLRDAFEMARALRDGATAATLARFARERAFDRAVTIGLTDLLPRAFAVPGRSFGHLRGAALTLLECLPPLKHG
LARQMMFGQRG

Sequences:

>Translated_411_residues
MTDSITASSAAPDFDVAIVGAGPVGLALANWLLRDTDWRIALFDARDAEAAARDPRALALSHGSRVLLQEIGGWPTRATP
ITHIHVSQRGHFGQAHIRREDYDVPALGHVVQYGDLSAALNAALDTQMERHPGRLTRYDHTPVERVEQLPRADGTVAPAR
VRALREGRHPLAIETEVVIQAEGGLFDDARKQQRGIAQARRRDYGQTAIVAHVRCSAPLEGWAWERFTPEGPLALLPQDD
AQGPGYALVWCCAPDEARRRAALPDDAFLAELGAAFGERMGRFTHASPRHTFALGLHAQRIPVDRRVAAIGNAAQTIHPV
AGQGFNLGLRDAFEMARALRDGATAATLARFARERAFDRAVTIGLTDLLPRAFAVPGRSFGHLRGAALTLLECLPPLKHG
LARQMMFGQRG
>Mature_410_residues
TDSITASSAAPDFDVAIVGAGPVGLALANWLLRDTDWRIALFDARDAEAAARDPRALALSHGSRVLLQEIGGWPTRATPI
THIHVSQRGHFGQAHIRREDYDVPALGHVVQYGDLSAALNAALDTQMERHPGRLTRYDHTPVERVEQLPRADGTVAPARV
RALREGRHPLAIETEVVIQAEGGLFDDARKQQRGIAQARRRDYGQTAIVAHVRCSAPLEGWAWERFTPEGPLALLPQDDA
QGPGYALVWCCAPDEARRRAALPDDAFLAELGAAFGERMGRFTHASPRHTFALGLHAQRIPVDRRVAAIGNAAQTIHPVA
GQGFNLGLRDAFEMARALRDGATAATLARFARERAFDRAVTIGLTDLLPRAFAVPGRSFGHLRGAALTLLECLPPLKHGL
ARQMMFGQRG

Specific function: Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiH/COQ6 family [H]

Homologues:

Organism=Homo sapiens, GI32967305, Length=408, Percent_Identity=25.7352941176471, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI32967307, Length=362, Percent_Identity=25.9668508287293, Blast_Score=87, Evalue=4e-17,
Organism=Escherichia coli, GI1789274, Length=415, Percent_Identity=35.6626506024096, Blast_Score=174, Evalue=8e-45,
Organism=Escherichia coli, GI1789273, Length=410, Percent_Identity=30.2439024390244, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1786883, Length=389, Percent_Identity=27.7634961439589, Blast_Score=88, Evalue=9e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042
- InterPro:   IPR018168
- InterPro:   IPR010971
- InterPro:   IPR011295 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.14.13.-

Molecular weight: Translated: 44689; Mature: 44558

Theoretical pI: Translated: 8.66; Mature: 8.66

Prosite motif: PS01304 UBIH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDSITASSAAPDFDVAIVGAGPVGLALANWLLRDTDWRIALFDARDAEAAARDPRALAL
CCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHCCCCEEEE
SHGSRVLLQEIGGWPTRATPITHIHVSQRGHFGQAHIRREDYDVPALGHVVQYGDLSAAL
CCCCCHHHHHCCCCCCCCCCEEEEEECCCCCCCHHHCCCCCCCCCHHHHHHHHCCHHHHH
NAALDTQMERHPGRLTRYDHTPVERVEQLPRADGTVAPARVRALREGRHPLAIETEVVIQ
HHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHCCCCCEEEEEEEEEE
AEGGLFDDARKQQRGIAQARRRDYGQTAIVAHVRCSAPLEGWAWERFTPEGPLALLPQDD
ECCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCCCCCCEEECCCCC
AQGPGYALVWCCAPDEARRRAALPDDAFLAELGAAFGERMGRFTHASPRHTFALGLHAQR
CCCCCEEEEEEECCHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHH
IPVDRRVAAIGNAAQTIHPVAGQGFNLGLRDAFEMARALRDGATAATLARFARERAFDRA
CCCHHHHHHHCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
VTIGLTDLLPRAFAVPGRSFGHLRGAALTLLECLPPLKHGLARQMMFGQRG
HEECHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TDSITASSAAPDFDVAIVGAGPVGLALANWLLRDTDWRIALFDARDAEAAARDPRALAL
CCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHCCCCEEEE
SHGSRVLLQEIGGWPTRATPITHIHVSQRGHFGQAHIRREDYDVPALGHVVQYGDLSAAL
CCCCCHHHHHCCCCCCCCCCEEEEEECCCCCCCHHHCCCCCCCCCHHHHHHHHCCHHHHH
NAALDTQMERHPGRLTRYDHTPVERVEQLPRADGTVAPARVRALREGRHPLAIETEVVIQ
HHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHCCCCCEEEEEEEEEE
AEGGLFDDARKQQRGIAQARRRDYGQTAIVAHVRCSAPLEGWAWERFTPEGPLALLPQDD
ECCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCCCCCCEEECCCCC
AQGPGYALVWCCAPDEARRRAALPDDAFLAELGAAFGERMGRFTHASPRHTFALGLHAQR
CCCCCEEEEEEECCHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHH
IPVDRRVAAIGNAAQTIHPVAGQGFNLGLRDAFEMARALRDGATAATLARFARERAFDRA
CCCHHHHHHHCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
VTIGLTDLLPRAFAVPGRSFGHLRGAALTLLECLPPLKHGLARQMMFGQRG
HEECHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1339425; 9278503 [H]