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The map label for this gene is erpA

Identifier: 187927473

GI number: 187927473

Start: 394113

End: 394487

Strand: Direct

Name: erpA

Synonym: Rpic_0370

Alternate gene names: 187927473

Gene position: 394113-394487 (Clockwise)

Preceding gene: 187927472

Following gene: 187927475

Centisome position: 10.0

GC content: 57.6

Gene sequence:

>375_bases
ATGAACGCAGTCGCGCAGGCAGCCACGCCCGATGTGAACGAGGTTCCGGCTCCGCTGGTCTTTACCGACAGCGCTGCGGA
CAAGGTCAAGCAACTGATTGAAGAGGAAGGCAACCCGGAGTTGAAGCTGCGCGTGTTCGTGCAAGGCGGCGGGTGCTCGG
GCTTCCAGTACGGCTTCACCTTTGACGAAGAGACCAACGAAGACGATACGACCATGACCAAGAATGGCGTGTCACTCTTG
ATCGACTCGATGAGCTACCAGTATCTGGTGGGCGCCGAGATCGACTACAAGGAAGACATCAACGGCGCGCAATTCGTCAT
CAAGAACCCGAATGCTTCGACCACGTGTGGTTGCGGCTCGTCGTTCTCGGTCTGA

Upstream 100 bases:

>100_bases
CGCACCGCACAATGCCCACTTGAAACGCGGGGCTTCGGCACGATTTGCAGCTTGCGCTTAAAATACAGGCAAGTTTTAGA
CGTTCCCACAGGAGATTTTC

Downstream 100 bases:

>100_bases
CGTCTCCCTCGCTTAAAAGAAAAAGCGCACTTCGGTGCGCTTTTTTGTTGCCCGCAAAATGGGTGCTCAAGCGGGGTAGA
TCGCGCCAAGGACGCGAGCG

Product: iron-sulfur cluster insertion protein ErpA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 124; Mature: 124

Protein sequence:

>124_residues
MNAVAQAATPDVNEVPAPLVFTDSAADKVKQLIEEEGNPELKLRVFVQGGGCSGFQYGFTFDEETNEDDTTMTKNGVSLL
IDSMSYQYLVGAEIDYKEDINGAQFVIKNPNASTTCGCGSSFSV

Sequences:

>Translated_124_residues
MNAVAQAATPDVNEVPAPLVFTDSAADKVKQLIEEEGNPELKLRVFVQGGGCSGFQYGFTFDEETNEDDTTMTKNGVSLL
IDSMSYQYLVGAEIDYKEDINGAQFVIKNPNASTTCGCGSSFSV
>Mature_124_residues
MNAVAQAATPDVNEVPAPLVFTDSAADKVKQLIEEEGNPELKLRVFVQGGGCSGFQYGFTFDEETNEDDTTMTKNGVSLL
IDSMSYQYLVGAEIDYKEDINGAQFVIKNPNASTTCGCGSSFSV

Specific function: Required for insertion of 4Fe-4S clusters (Potential)

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family

Homologues:

Organism=Homo sapiens, GI160420328, Length=121, Percent_Identity=38.0165289256198, Blast_Score=85, Evalue=2e-17,
Organism=Homo sapiens, GI52426768, Length=109, Percent_Identity=36.697247706422, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1786351, Length=112, Percent_Identity=61.6071428571429, Blast_Score=156, Evalue=3e-40,
Organism=Escherichia coli, GI1788877, Length=107, Percent_Identity=36.4485981308411, Blast_Score=68, Evalue=2e-13,
Organism=Escherichia coli, GI1787974, Length=106, Percent_Identity=29.2452830188679, Blast_Score=59, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI71998452, Length=105, Percent_Identity=39.0476190476191, Blast_Score=81, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI25146411, Length=113, Percent_Identity=30.9734513274336, Blast_Score=75, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI193209025, Length=108, Percent_Identity=31.4814814814815, Blast_Score=73, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6323001, Length=97, Percent_Identity=39.1752577319588, Blast_Score=77, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24649697, Length=83, Percent_Identity=46.9879518072289, Blast_Score=82, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24642263, Length=109, Percent_Identity=33.9449541284404, Blast_Score=73, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ERPA_RALPJ (B2UFK5)

Other databases:

- EMBL:   CP001068
- RefSeq:   YP_001897960.1
- ProteinModelPortal:   B2UFK5
- SMR:   B2UFK5
- GeneID:   6287848
- GenomeReviews:   CP001068_GR
- KEGG:   rpi:Rpic_0370
- HOGENOM:   HBG730174
- OMA:   TFDDQIN
- ProtClustDB:   PRK13623
- HAMAP:   MF_01380
- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR017870
- InterPro:   IPR023063
- Gene3D:   G3DSA:2.60.300.12
- PANTHER:   PTHR10072
- TIGRFAMs:   TIGR00049

Pfam domain/function: PF01521 Fe-S_biosyn; SSF89360 HesB_yadR_yfhF-like

EC number: NA

Molecular weight: Translated: 13304; Mature: 13304

Theoretical pI: Translated: 3.81; Mature: 3.81

Prosite motif: PS01152 HESB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAVAQAATPDVNEVPAPLVFTDSAADKVKQLIEEEGNPELKLRVFVQGGGCSGFQYGFT
CCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCEE
FDEETNEDDTTMTKNGVSLLIDSMSYQYLVGAEIDYKEDINGAQFVIKNPNASTTCGCGS
ECCCCCCCCCEEECCCEEEEEECCCCEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCCC
SFSV
CCCC
>Mature Secondary Structure
MNAVAQAATPDVNEVPAPLVFTDSAADKVKQLIEEEGNPELKLRVFVQGGGCSGFQYGFT
CCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCEE
FDEETNEDDTTMTKNGVSLLIDSMSYQYLVGAEIDYKEDINGAQFVIKNPNASTTCGCGS
ECCCCCCCCCEEECCCEEEEEECCCCEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCCC
SFSV
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA