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The map label for this gene is ttuD [H]

Identifier: 187927465

GI number: 187927465

Start: 387039

End: 388337

Strand: Direct

Name: ttuD [H]

Synonym: Rpic_0362

Alternate gene names: 187927465

Gene position: 387039-388337 (Clockwise)

Preceding gene: 187927463

Following gene: 187927466

Centisome position: 9.82

GC content: 68.51

Gene sequence:

>1299_bases
ATGAAGCTCGATCGCACCGCCGCCCGTGCCCTCCTGCTGGAGAGCTACGCCGCCGCCGTGGGCGCGGCGGACCCACTGAA
GATCGTCGCTGACTTCCTCCCCCCGCCGCATGCCGGCGGCAAGACGCTCGTGGTCGGCGCCGGCAAGGCGGCTGCCTCGA
TGGCGCTGGCCGTCGAGCAGGCCTATGCCGGCCGCGCAAAGATCGAAGGCCTGGTCATCACGCGTTATGCGCATGGCCTG
CCGACCGAGCACATCCGCGTTATCGAAGCCGGACACCCGGTGCCGGACGAGGCGGGCGAACAGGCGGCGCAGGAAATCCT
GGATCGGGTTTGCGCGCTCACCGAGCGCGACCGCCTGATCGTGCTGGTTTCGGGTGGCGGCTCCAGCCTGCTGTCGTTGC
CCGCCGAGGGCATCCCGATGGGCGATCTGAAAGACGTGACGCGCGAGTTGCTGCGCTGCGGCGCTCCGATCACCGACATG
AACATCGTGCGCAAGCATTTGTCGCGCATTCAAGGCGGGCGGCTTGCCGCCGCTTCGCGCGCGCCGGCCACGACGCTGAT
CGTCTCCGACGTGGCGGGCGACGATCCAAGCGCCATTGCCAGCGGCCCGACCGTGCCGGATGCGAGCACCTACGCCGATG
CGCTGGCCATCATCAAGCGTTGGGGTGCGCAGATACCCGATACCGTGCACGCGCACCTCGAACGTGGCGCACGCGGCGAG
ATTGCCGAAACGCCCAAACCCGGCGACGCCTGTTTTGCACGCGTGACCAACCACGTCATCGCCACTGCGCAACAGAGTTT
GCAGGCCGGCGCGCAGGTATTTGCGACGCGTGGCATCCACACCGCCATCCTCGGCGACACGGTGACCGGCGAGGCGCGTG
AGGTCGCCCAGGTGTACGGCGCGCTGGCGAGGCAGGTGCGCCAGCACGGCACGCCGTTTGTGGCGCCGGTGGCACTCATC
TCCGGTGGCGAATGCACGGTGACGATTCCGCCGGGCGTGACCGGCGGCCGCGGCGGGCGCTGCGCGGAGTTCCTGCTCTC
GCTCGGTGTCACGCTCGAAGACATGGGTGATATCTACGCACTGGCCGCCGATACAGACGGCATCGATGGATCGGAGGACA
ATGCGGGTGCGCTGCTTGACCCCGGCTCCATCGCGCGCGCCGCCGCCAAGGGCGTTGCCGCCCGCGCCGCGCTCGATGCA
CACGACGCCTACGGTTTCTTTGCTGCCGCCGATGACTTGATCGTCACCGGCCCGACGCGCACCAACGTCAACGACTACCG
CGTCATCCTCATTCTCTGA

Upstream 100 bases:

>100_bases
CCAAGCGCCTTCGTCTTCACGGCGCCGCGCCCCGCTGCCGGGCGTTGCGCACATGCCGCACACCATCGCCCCCAGATTGC
CCACACCGGACGTCATCCCC

Downstream 100 bases:

>100_bases
TTCACGTTTTTGCTGACCGCTTCCGCACGCACCATGACCGACACTCTTACGATCGTCCGCCCCGATGACTGGCACCTGCA
CCTGCGCGACGGCGATGCGC

Product: Hydroxypyruvate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MKLDRTAARALLLESYAAAVGAADPLKIVADFLPPPHAGGKTLVVGAGKAAASMALAVEQAYAGRAKIEGLVITRYAHGL
PTEHIRVIEAGHPVPDEAGEQAAQEILDRVCALTERDRLIVLVSGGGSSLLSLPAEGIPMGDLKDVTRELLRCGAPITDM
NIVRKHLSRIQGGRLAAASRAPATTLIVSDVAGDDPSAIASGPTVPDASTYADALAIIKRWGAQIPDTVHAHLERGARGE
IAETPKPGDACFARVTNHVIATAQQSLQAGAQVFATRGIHTAILGDTVTGEAREVAQVYGALARQVRQHGTPFVAPVALI
SGGECTVTIPPGVTGGRGGRCAEFLLSLGVTLEDMGDIYALAADTDGIDGSEDNAGALLDPGSIARAAAKGVAARAALDA
HDAYGFFAAADDLIVTGPTRTNVNDYRVILIL

Sequences:

>Translated_432_residues
MKLDRTAARALLLESYAAAVGAADPLKIVADFLPPPHAGGKTLVVGAGKAAASMALAVEQAYAGRAKIEGLVITRYAHGL
PTEHIRVIEAGHPVPDEAGEQAAQEILDRVCALTERDRLIVLVSGGGSSLLSLPAEGIPMGDLKDVTRELLRCGAPITDM
NIVRKHLSRIQGGRLAAASRAPATTLIVSDVAGDDPSAIASGPTVPDASTYADALAIIKRWGAQIPDTVHAHLERGARGE
IAETPKPGDACFARVTNHVIATAQQSLQAGAQVFATRGIHTAILGDTVTGEAREVAQVYGALARQVRQHGTPFVAPVALI
SGGECTVTIPPGVTGGRGGRCAEFLLSLGVTLEDMGDIYALAADTDGIDGSEDNAGALLDPGSIARAAAKGVAARAALDA
HDAYGFFAAADDLIVTGPTRTNVNDYRVILIL
>Mature_432_residues
MKLDRTAARALLLESYAAAVGAADPLKIVADFLPPPHAGGKTLVVGAGKAAASMALAVEQAYAGRAKIEGLVITRYAHGL
PTEHIRVIEAGHPVPDEAGEQAAQEILDRVCALTERDRLIVLVSGGGSSLLSLPAEGIPMGDLKDVTRELLRCGAPITDM
NIVRKHLSRIQGGRLAAASRAPATTLIVSDVAGDDPSAIASGPTVPDASTYADALAIIKRWGAQIPDTVHAHLERGARGE
IAETPKPGDACFARVTNHVIATAQQSLQAGAQVFATRGIHTAILGDTVTGEAREVAQVYGALARQVRQHGTPFVAPVALI
SGGECTVTIPPGVTGGRGGRCAEFLLSLGVTLEDMGDIYALAADTDGIDGSEDNAGALLDPGSIARAAAKGVAARAALDA
HDAYGFFAAADDLIVTGPTRTNVNDYRVILIL

Specific function: Degrades an unidentified toxic product from the first step of tartrate degradation [H]

COG id: COG2379

COG function: function code G; Putative glycerate kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI31543063, Length=448, Percent_Identity=31.25, Blast_Score=149, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI193205461, Length=430, Percent_Identity=26.2790697674419, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI19920578, Length=477, Percent_Identity=29.559748427673, Blast_Score=117, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007835 [H]

Pfam domain/function: PF05161 MOFRL [H]

EC number: =1.1.1.81 [H]

Molecular weight: Translated: 44441; Mature: 44441

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLDRTAARALLLESYAAAVGAADPLKIVADFLPPPHAGGKTLVVGAGKAAASMALAVEQ
CCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHH
AYAGRAKIEGLVITRYAHGLPTEHIRVIEAGHPVPDEAGEQAAQEILDRVCALTERDRLI
HHCCCHHCCEEEEEEECCCCCHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEE
VLVSGGGSSLLSLPAEGIPMGDLKDVTRELLRCGAPITDMNIVRKHLSRIQGGRLAAASR
EEEECCCCCEEECCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEECCC
APATTLIVSDVAGDDPSAIASGPTVPDASTYADALAIIKRWGAQIPDTVHAHLERGARGE
CCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCC
IAETPKPGDACFARVTNHVIATAQQSLQAGAQVFATRGIHTAILGDTVTGEAREVAQVYG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHH
ALARQVRQHGTPFVAPVALISGGECTVTIPPGVTGGRGGRCAEFLLSLGVTLEDMGDIYA
HHHHHHHHCCCCEEEHHHEECCCEEEEEECCCCCCCCCCHHHHHHHHHCCCHHHCCCEEE
LAADTDGIDGSEDNAGALLDPGSIARAAAKGVAARAALDAHDAYGFFAAADDLIVTGPTR
EEECCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHCHHHCEEEEECCCEEEECCCC
TNVNDYRVILIL
CCCCCEEEEEEC
>Mature Secondary Structure
MKLDRTAARALLLESYAAAVGAADPLKIVADFLPPPHAGGKTLVVGAGKAAASMALAVEQ
CCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHH
AYAGRAKIEGLVITRYAHGLPTEHIRVIEAGHPVPDEAGEQAAQEILDRVCALTERDRLI
HHCCCHHCCEEEEEEECCCCCHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEE
VLVSGGGSSLLSLPAEGIPMGDLKDVTRELLRCGAPITDMNIVRKHLSRIQGGRLAAASR
EEEECCCCCEEECCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEECCC
APATTLIVSDVAGDDPSAIASGPTVPDASTYADALAIIKRWGAQIPDTVHAHLERGARGE
CCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCC
IAETPKPGDACFARVTNHVIATAQQSLQAGAQVFATRGIHTAILGDTVTGEAREVAQVYG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHH
ALARQVRQHGTPFVAPVALISGGECTVTIPPGVTGGRGGRCAEFLLSLGVTLEDMGDIYA
HHHHHHHHCCCCEEEHHHEECCCEEEEEECCCCCCCCCCHHHHHHHHHCCCHHHCCCEEE
LAADTDGIDGSEDNAGALLDPGSIARAAAKGVAARAALDAHDAYGFFAAADDLIVTGPTR
EEECCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHCHHHCEEEEECCCEEEECCCC
TNVNDYRVILIL
CCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]