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The map label for this gene is gltK [H]

Identifier: 187927462

GI number: 187927462

Start: 384446

End: 385129

Strand: Direct

Name: gltK [H]

Synonym: Rpic_0359

Alternate gene names: 187927462

Gene position: 384446-385129 (Clockwise)

Preceding gene: 187927461

Following gene: 187927463

Centisome position: 9.75

GC content: 60.38

Gene sequence:

>684_bases
ATGGCTTATCAATTCGATTTCTCGTCCATCAACGTCGACAACATGCGCGTGCTCGGCGAGGGCATGCTCCTTTCGCTCGA
GATCACAGGCACGGCCATCCTGGTCGGCATCGTGTGGGGCACGCTGCTGGCGATGATGCGCCTGTCGGGCATCAAGCCGC
TGCAGGTGTTCGGGCAGGCGTACGTGAACCTCTTCCGGTCCATCCCGCTGGTGATGGTGCTGCTGTGGTTCTTCCTGATC
GTGCCGCAGGTACTGCAGAAAATCTTCAACCTGTCGCCGGCCACCGACATGCGCATGACGTCCGCGCTGGTCGCCTTCGC
GCTGTTTGAAGCGGCGTATTACTCGGAGATCATCCGCGCCGGTATCCAGAGCGTCTCGCGCGGGCAGATGTTCGCCGCCT
ACGCGATGGGTATGACGTACGGCCAGGCCATGCGCCTGGTGATCCTGCCGCAGGCATTCCGCAACATGATTCCGTTGCTG
CTCACCCAGGCCATCGTCCTGTTCCAGGATACGTCGCTGGTGTATGTGAGCGCGCTGTCGGACTTCTTTACGCAGGCATA
CAACATCGGTGAGCGCGACGGCCGTATCGTCGAGCTGCTGCTGTTTGCCGGCTTGTGCTATTTCGTGATCTGCTTCGGCG
CCTCCGTGCTGGTGAAGCGACTTCAGAAGAAGGTGACCCAATGA

Upstream 100 bases:

>100_bases
TGCTGATCAACCTGACCGTTATGGGCCTCATGCGCTGGGTGGAAGCACGTTCCCGGCTGCCTGGCTTTATCGGTGGCAAG
TAATCGGGCGAGGACTCTTC

Downstream 100 bases:

>100_bases
TCGAGATCAAGAACGTTTCCAAGTGGTACGGCAGCTTCCAGGTGCTGACCGACTGCACCACCAGCGTGAAGAAGAGCGAG
GTGGTGGTGGTGTGCGGCCC

Product: polar amino acid ABC transporter inner membrane subunit

Products: ADP; phosphate; L-glutamate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MAYQFDFSSINVDNMRVLGEGMLLSLEITGTAILVGIVWGTLLAMMRLSGIKPLQVFGQAYVNLFRSIPLVMVLLWFFLI
VPQVLQKIFNLSPATDMRMTSALVAFALFEAAYYSEIIRAGIQSVSRGQMFAAYAMGMTYGQAMRLVILPQAFRNMIPLL
LTQAIVLFQDTSLVYVSALSDFFTQAYNIGERDGRIVELLLFAGLCYFVICFGASVLVKRLQKKVTQ

Sequences:

>Translated_227_residues
MAYQFDFSSINVDNMRVLGEGMLLSLEITGTAILVGIVWGTLLAMMRLSGIKPLQVFGQAYVNLFRSIPLVMVLLWFFLI
VPQVLQKIFNLSPATDMRMTSALVAFALFEAAYYSEIIRAGIQSVSRGQMFAAYAMGMTYGQAMRLVILPQAFRNMIPLL
LTQAIVLFQDTSLVYVSALSDFFTQAYNIGERDGRIVELLLFAGLCYFVICFGASVLVKRLQKKVTQ
>Mature_226_residues
AYQFDFSSINVDNMRVLGEGMLLSLEITGTAILVGIVWGTLLAMMRLSGIKPLQVFGQAYVNLFRSIPLVMVLLWFFLIV
PQVLQKIFNLSPATDMRMTSALVAFALFEAAYYSEIIRAGIQSVSRGQMFAAYAMGMTYGQAMRLVILPQAFRNMIPLLL
TQAIVLFQDTSLVYVSALSDFFTQAYNIGERDGRIVELLLFAGLCYFVICFGASVLVKRLQKKVTQ

Specific function: Part of the binding-protein-dependent transport system for aspartate/glutamate; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786873, Length=222, Percent_Identity=63.5135135135135, Blast_Score=289, Evalue=1e-79,
Organism=Escherichia coli, GI87082239, Length=207, Percent_Identity=33.3333333333333, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1788226, Length=216, Percent_Identity=32.4074074074074, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1786874, Length=221, Percent_Identity=28.0542986425339, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1787030, Length=224, Percent_Identity=28.125, Blast_Score=81, Evalue=5e-17,
Organism=Escherichia coli, GI1787087, Length=228, Percent_Identity=24.1228070175439, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1788645, Length=217, Percent_Identity=25.8064516129032, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI48994930, Length=123, Percent_Identity=30.0813008130081, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788646, Length=165, Percent_Identity=25.4545454545455, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 25364; Mature: 25233

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYQFDFSSINVDNMRVLGEGMLLSLEITGTAILVGIVWGTLLAMMRLSGIKPLQVFGQA
CCEECCCCCCCCCHHHEECCCEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
YVNLFRSIPLVMVLLWFFLIVPQVLQKIFNLSPATDMRMTSALVAFALFEAAYYSEIIRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GIQSVSRGQMFAAYAMGMTYGQAMRLVILPQAFRNMIPLLLTQAIVLFQDTSLVYVSALS
HHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
DFFTQAYNIGERDGRIVELLLFAGLCYFVICFGASVLVKRLQKKVTQ
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AYQFDFSSINVDNMRVLGEGMLLSLEITGTAILVGIVWGTLLAMMRLSGIKPLQVFGQA
CEECCCCCCCCCHHHEECCCEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
YVNLFRSIPLVMVLLWFFLIVPQVLQKIFNLSPATDMRMTSALVAFALFEAAYYSEIIRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GIQSVSRGQMFAAYAMGMTYGQAMRLVILPQAFRNMIPLLLTQAIVLFQDTSLVYVSALS
HHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
DFFTQAYNIGERDGRIVELLLFAGLCYFVICFGASVLVKRLQKKVTQ
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamate [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamate [Periplasm] + H2O = ADP + phosphate + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]