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The map label for this gene is qseD [H]

Identifier: 187927458

GI number: 187927458

Start: 379773

End: 380717

Strand: Direct

Name: qseD [H]

Synonym: Rpic_0355

Alternate gene names: 187927458

Gene position: 379773-380717 (Clockwise)

Preceding gene: 187927457

Following gene: 187927459

Centisome position: 9.63

GC content: 64.97

Gene sequence:

>945_bases
ATGGAACTCAAATGGCTGGAAGACTTCATCAGCCTGGCCGAGACGCGCAGCTTTTCGCGCTCGGCCGAGCTGCGGCACGT
GACGCAGCCGGCGTTTTCGCGGCGCATTCAATCCCTCGAGGCCTGGCTCGGCAATGAGCTGATCGACCGATCAAGCTACC
CAACACGCCTGACGCCCGCCGGAGAGGTCTTCTACGAACAGGCTTTGGCGATGCTCGCCCAGGTGAGTGAGACGCGCGCA
CTGATGCGCGGCCAGCGTCCGGCCAGTGCGTCGACGATCGACTTTGCCGTGCCGCATACGCTATCGCTGACGTTCTTCCC
CGGCTGGCTCGCGCAGGTGGAAGAGAAGATCGGCAAGCTGCAATGCAGGCTGCGCGCGCTCAATGTGCACGATGCGGTGA
TGACGCTGGTGGAGGGCGGCTGCGATCTCGTGATGGTCTATCACCACGCGCGGCAGATGATCCAGCTCGACCCCACGCGC
TACGACATGCTGGTGCTGGGCACCGAGCGGCTTTCGCCGTTCTCCAAGCCCGATGCCAGCGGGCGGCCGATCTATCGACT
CGTTCCCACCGCACGCAAACCCATCGCCTACCTGAGCTATACGCCCAATGCCTTTCTCGGGCGCATGGTGGATGTGCTGC
TGGAAAACTCGCCGGTGGCGCCGCTGCTCGACAAGTGCTACGAAACCGACATGGCCGAGGCGCTCAAGGTGATGGCGCTG
GCGGGCCATGGCGTGGCCTTCCTGCCCGAGAGTGCGGTGCGTGAGGATGTGGCAGCGGGTCGCCTCGTGCGCGCGGAAGG
CAAGGGCGGCGGTACGTTGTCGATCGAGATGGAAATCCGGCTTTACCGTGAGCACCCCCAGAGCGGCGCACACGACCGTC
GGCACCCCCAGTCCAAGCGCAAACGCGAGCTGATCGACACGCTGTGGAGCGCGCTGGCGGGCTGA

Upstream 100 bases:

>100_bases
AGGCCGTTACGCGCAGATGTGGCGCATGCAGGCACGCGAGCCAGAGCGCGTTGCCGAAGAAGCAGAAGACGCCCGAGCAG
GTTGAGGGAGAGGCAATCCG

Downstream 100 bases:

>100_bases
ACGGGCCATCGAATTCGTCCCCGGGGTTATGCGTTCAATGCATAACCCGATGTAAAAATGGCATTGGATTTCGTTCCGGG
CGGTCCCTAAGCTGGCGGGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Quorum-sensing regulator protein D [H]

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MELKWLEDFISLAETRSFSRSAELRHVTQPAFSRRIQSLEAWLGNELIDRSSYPTRLTPAGEVFYEQALAMLAQVSETRA
LMRGQRPASASTIDFAVPHTLSLTFFPGWLAQVEEKIGKLQCRLRALNVHDAVMTLVEGGCDLVMVYHHARQMIQLDPTR
YDMLVLGTERLSPFSKPDASGRPIYRLVPTARKPIAYLSYTPNAFLGRMVDVLLENSPVAPLLDKCYETDMAEALKVMAL
AGHGVAFLPESAVREDVAAGRLVRAEGKGGGTLSIEMEIRLYREHPQSGAHDRRHPQSKRKRELIDTLWSALAG

Sequences:

>Translated_314_residues
MELKWLEDFISLAETRSFSRSAELRHVTQPAFSRRIQSLEAWLGNELIDRSSYPTRLTPAGEVFYEQALAMLAQVSETRA
LMRGQRPASASTIDFAVPHTLSLTFFPGWLAQVEEKIGKLQCRLRALNVHDAVMTLVEGGCDLVMVYHHARQMIQLDPTR
YDMLVLGTERLSPFSKPDASGRPIYRLVPTARKPIAYLSYTPNAFLGRMVDVLLENSPVAPLLDKCYETDMAEALKVMAL
AGHGVAFLPESAVREDVAAGRLVRAEGKGGGTLSIEMEIRLYREHPQSGAHDRRHPQSKRKRELIDTLWSALAG
>Mature_314_residues
MELKWLEDFISLAETRSFSRSAELRHVTQPAFSRRIQSLEAWLGNELIDRSSYPTRLTPAGEVFYEQALAMLAQVSETRA
LMRGQRPASASTIDFAVPHTLSLTFFPGWLAQVEEKIGKLQCRLRALNVHDAVMTLVEGGCDLVMVYHHARQMIQLDPTR
YDMLVLGTERLSPFSKPDASGRPIYRLVPTARKPIAYLSYTPNAFLGRMVDVLLENSPVAPLLDKCYETDMAEALKVMAL
AGHGVAFLPESAVREDVAAGRLVRAEGKGGGTLSIEMEIRLYREHPQSGAHDRRHPQSKRKRELIDTLWSALAG

Specific function: Down-regulates expression of the flagellar regulon, decreasing motility [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790783, Length=264, Percent_Identity=32.5757575757576, Blast_Score=141, Evalue=6e-35,
Organism=Escherichia coli, GI1787879, Length=273, Percent_Identity=25.2747252747253, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1790399, Length=146, Percent_Identity=28.0821917808219, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35144; Mature: 35144

Theoretical pI: Translated: 8.11; Mature: 8.11

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELKWLEDFISLAETRSFSRSAELRHVTQPAFSRRIQSLEAWLGNELIDRSSYPTRLTPA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
GEVFYEQALAMLAQVSETRALMRGQRPASASTIDFAVPHTLSLTFFPGWLAQVEEKIGKL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCEEEEEECCHHHHHHHHHHHHH
QCRLRALNVHDAVMTLVEGGCDLVMVYHHARQMIQLDPTRYDMLVLGTERLSPFSKPDAS
HHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHEEECCCCEEEEEEEHHHCCCCCCCCCC
GRPIYRLVPTARKPIAYLSYTPNAFLGRMVDVLLENSPVAPLLDKCYETDMAEALKVMAL
CCCEEEECCCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
AGHGVAFLPESAVREDVAAGRLVRAEGKGGGTLSIEMEIRLYREHPQSGAHDRRHPQSKR
HCCCEEECCHHHHHHHHHHCCEEEECCCCCCEEEEEEEEEEEECCCCCCCCCCCCCHHHH
KRELIDTLWSALAG
HHHHHHHHHHHHCC
>Mature Secondary Structure
MELKWLEDFISLAETRSFSRSAELRHVTQPAFSRRIQSLEAWLGNELIDRSSYPTRLTPA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
GEVFYEQALAMLAQVSETRALMRGQRPASASTIDFAVPHTLSLTFFPGWLAQVEEKIGKL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCEEEEEECCHHHHHHHHHHHHH
QCRLRALNVHDAVMTLVEGGCDLVMVYHHARQMIQLDPTRYDMLVLGTERLSPFSKPDAS
HHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHEEECCCCEEEEEEEHHHCCCCCCCCCC
GRPIYRLVPTARKPIAYLSYTPNAFLGRMVDVLLENSPVAPLLDKCYETDMAEALKVMAL
CCCEEEECCCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
AGHGVAFLPESAVREDVAAGRLVRAEGKGGGTLSIEMEIRLYREHPQSGAHDRRHPQSKR
HCCCEEECCHHHHHHHHHHCCEEEECCCCCCEEEEEEEEEEEECCCCCCCCCCCCCHHHH
KRELIDTLWSALAG
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 7876157 [H]