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The map label for this gene is hprK

Identifier: 187927367

GI number: 187927367

Start: 275471

End: 276445

Strand: Reverse

Name: hprK

Synonym: Rpic_0260

Alternate gene names: 187927367

Gene position: 276445-275471 (Counterclockwise)

Preceding gene: 187927368

Following gene: 187927366

Centisome position: 7.01

GC content: 63.49

Gene sequence:

>975_bases
ATGGAACTGACCGGCGTCATCGCCCAATCGATCTTTGACGACAACGCAGCTGATCTGAAGCTCTCGTGGGTCGCCGGCCT
GGAGGGCGCGGACCGCGCGTTCGACGTGGACTTCGCCAAGGAGGCGACGTCTGCAGCCGACCTGGTCGGGCACTTGAACC
TCATCCACCCGAACCGCATCCAGGTGCTCGGCAAGCCCGAGATCACCTACTACCAACGCTTGTCGGAAGAAAACCGCAAG
CGCCAGATGGGCGAGTTGATCCTGCTGGAGCCGCCCTTCCTGGTGGTGGCCGATGGCGTCGATCCGCCGCCCGATCTGGA
ACTGCGCTGCACGCGCTCGTCCACACCGCTGTTCACGTCACCGATTTCCTCGGCTGCCGTCATTGATCATCTGCGCCTGT
ATCTGTCGCGCATCTCGGCGCCGCGCGTGACGATGCACGGGGTGTTTCTCGACATCCTCGGCATGGGCGTGCTGATCATG
GGCGATTCGGGTCTGGGCAAGAGCGAGTTGGGCCTGGAACTGATCTCGCGCGGCCACGGCCTTGTTGCCGACGACGCAGT
CGACTTCGTGCGGTTGGGGCCGGACTTTATCGAAGGCCGCTGCCCGCCGCTGCTGCAGAATCTGCTGGAAGTGCGCGGCC
TGGGCCTGCTCGACATCAAGACGATCTTCGGTGAAACGGCGGTGCGCCGGAAGATGAAGATCAAGCTGATCGTGCAACTC
GTGCGCCGCAACGATGGCGAATTCGAGCGCCTGCCGCTCGATTCGCAGTACCTCGATGTGCTCGGTCTGCCAATCCACAT
GGTGAAGATTCAGGTGGCTGCTGGCCGCAACTTGGCCGTGCTGGTCGAAGCCGCGGTGCGCAACACCATCCTGCGCCTGC
GCGGCATTGATACGTTGCGCGACTTCATGGACCGCCAGCGAGCCGCCATGCAGGCTGAAGCCGCTTCCCACTCGCCCCAG
GGCCGTCTGCTTTAA

Upstream 100 bases:

>100_bases
CAGCTACTGACCGACTGGCGGCCCTGATCGCGGCGCAATCGGGGGCAAGCGCAACCGATTGCGAACGCGCTATGCCCCGT
CGGCATCACTGTGCCCTGCT

Downstream 100 bases:

>100_bases
CAAAGCCGCTACAAAGTTTCGTCTCCAGGTCGGTTTTACCCTAGTTTTCGCTGCGAAACGTCAACCCGACATGCTGCCTC
TCCGTTGTGGGAGGGAATGC

Product: HPr kinase/phosphorylase

Products: NA

Alternate protein names: HPrK/P; HPr(Ser) kinase/phosphorylase

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MELTGVIAQSIFDDNAADLKLSWVAGLEGADRAFDVDFAKEATSAADLVGHLNLIHPNRIQVLGKPEITYYQRLSEENRK
RQMGELILLEPPFLVVADGVDPPPDLELRCTRSSTPLFTSPISSAAVIDHLRLYLSRISAPRVTMHGVFLDILGMGVLIM
GDSGLGKSELGLELISRGHGLVADDAVDFVRLGPDFIEGRCPPLLQNLLEVRGLGLLDIKTIFGETAVRRKMKIKLIVQL
VRRNDGEFERLPLDSQYLDVLGLPIHMVKIQVAAGRNLAVLVEAAVRNTILRLRGIDTLRDFMDRQRAAMQAEAASHSPQ
GRLL

Sequences:

>Translated_324_residues
MELTGVIAQSIFDDNAADLKLSWVAGLEGADRAFDVDFAKEATSAADLVGHLNLIHPNRIQVLGKPEITYYQRLSEENRK
RQMGELILLEPPFLVVADGVDPPPDLELRCTRSSTPLFTSPISSAAVIDHLRLYLSRISAPRVTMHGVFLDILGMGVLIM
GDSGLGKSELGLELISRGHGLVADDAVDFVRLGPDFIEGRCPPLLQNLLEVRGLGLLDIKTIFGETAVRRKMKIKLIVQL
VRRNDGEFERLPLDSQYLDVLGLPIHMVKIQVAAGRNLAVLVEAAVRNTILRLRGIDTLRDFMDRQRAAMQAEAASHSPQ
GRLL
>Mature_324_residues
MELTGVIAQSIFDDNAADLKLSWVAGLEGADRAFDVDFAKEATSAADLVGHLNLIHPNRIQVLGKPEITYYQRLSEENRK
RQMGELILLEPPFLVVADGVDPPPDLELRCTRSSTPLFTSPISSAAVIDHLRLYLSRISAPRVTMHGVFLDILGMGVLIM
GDSGLGKSELGLELISRGHGLVADDAVDFVRLGPDFIEGRCPPLLQNLLEVRGLGLLDIKTIFGETAVRRKMKIKLIVQL
VRRNDGEFERLPLDSQYLDVLGLPIHMVKIQVAAGRNLAVLVEAAVRNTILRLRGIDTLRDFMDRQRAAMQAEAASHSPQ
GRLL

Specific function: Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-pr

COG id: COG1493

COG function: function code T; Serine kinase of the HPr protein, regulates carbohydrate metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HPrK/P family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HPRK_RALPJ (B2UES6)

Other databases:

- EMBL:   CP001068
- RefSeq:   YP_001897854.1
- ProteinModelPortal:   B2UES6
- SMR:   B2UES6
- GeneID:   6289262
- GenomeReviews:   CP001068_GR
- KEGG:   rpi:Rpic_0260
- HOGENOM:   HBG566466
- OMA:   IHGVLVD
- ProtClustDB:   PRK05428
- HAMAP:   MF_01249
- InterPro:   IPR003755
- InterPro:   IPR011104
- InterPro:   IPR011126

Pfam domain/function: PF07475 Hpr_kinase_C; PF02603 Hpr_kinase_N

EC number: NA

Molecular weight: Translated: 35679; Mature: 35679

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: ACT_SITE 146-146 ACT_SITE 167-167 ACT_SITE 185-185 ACT_SITE 250-250

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELTGVIAQSIFDDNAADLKLSWVAGLEGADRAFDVDFAKEATSAADLVGHLNLIHPNRI
CCCHHHHHHHHHCCCCCCEEEEEEECCCCCCCEECCHHHHHHHHHHHHHHHHEEECCCEE
QVLGKPEITYYQRLSEENRKRQMGELILLEPPFLVVADGVDPPPDLELRCTRSSTPLFTS
EEECCCCHHHHHHHHHHHHHHHHCCEEEECCCEEEEECCCCCCCCCEEEEECCCCCCEEC
PISSAAVIDHLRLYLSRISAPRVTMHGVFLDILGMGVLIMGDSGLGKSELGLELISRGHG
CCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHCCCC
LVADDAVDFVRLGPDFIEGRCPPLLQNLLEVRGLGLLDIKTIFGETAVRRKMKIKLIVQL
CEEHHHHHHHHCCCHHHCCCCCHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHH
VRRNDGEFERLPLDSQYLDVLGLPIHMVKIQVAAGRNLAVLVEAAVRNTILRLRGIDTLR
HHCCCCCEEECCCCHHHHHHHCCCEEEEEEEEECCCCEEEEHHHHHHHHHHHHCCHHHHH
DFMDRQRAAMQAEAASHSPQGRLL
HHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MELTGVIAQSIFDDNAADLKLSWVAGLEGADRAFDVDFAKEATSAADLVGHLNLIHPNRI
CCCHHHHHHHHHCCCCCCEEEEEEECCCCCCCEECCHHHHHHHHHHHHHHHHEEECCCEE
QVLGKPEITYYQRLSEENRKRQMGELILLEPPFLVVADGVDPPPDLELRCTRSSTPLFTS
EEECCCCHHHHHHHHHHHHHHHHCCEEEECCCEEEEECCCCCCCCCEEEEECCCCCCEEC
PISSAAVIDHLRLYLSRISAPRVTMHGVFLDILGMGVLIMGDSGLGKSELGLELISRGHG
CCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHCCCC
LVADDAVDFVRLGPDFIEGRCPPLLQNLLEVRGLGLLDIKTIFGETAVRRKMKIKLIVQL
CEEHHHHHHHHCCCHHHCCCCCHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHH
VRRNDGEFERLPLDSQYLDVLGLPIHMVKIQVAAGRNLAVLVEAAVRNTILRLRGIDTLR
HHCCCCCEEECCCCHHHHHHHCCCEEEEEEEEECCCCEEEEHHHHHHHHHHHHCCHHHHH
DFMDRQRAAMQAEAASHSPQGRLL
HHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA