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The map label for this gene is gpmA [H]

Identifier: 187927317

GI number: 187927317

Start: 227340

End: 228095

Strand: Reverse

Name: gpmA [H]

Synonym: Rpic_0209

Alternate gene names: 187927317

Gene position: 228095-227340 (Counterclockwise)

Preceding gene: 187927322

Following gene: 187927316

Centisome position: 5.79

GC content: 64.95

Gene sequence:

>756_bases
ATGGCAGTCATGCATAAGCTCGTCCTCATCCGCCACGGCGAATCGACGTGGAATCTGGAGAACCGTTTCACCGGCTGGGT
CGACGTCGACCTGACCGACACGGGCGTCGCCCAGGCCCGCCAAGGCGGCAAGCTGCTGCGCGAAGCCGGCTTCACGTTCG
ATCTGGCCTACACCTCGGTGCTCAAGCGCGCGATCCGCACGCTCTGGCACGTGCAGGACGAAATGGACCTGATGTGGATC
CCGACCCGCAACGAATGGCGTCTGAACGAGCGTCACTACGGGGCGCTGTCGGGCCTGAACAAGGCAGAAACCGCCGCGCA
ATATGGCGACGAGCAAGTTCTCGTCTGGCGCCGCAGCTACGACACGCCGCCGCCCGCGCTGGAGCCCGGCGCCGACAACG
ACGCCTTCGGCAACCCGCGTTACGCGGGACTCACGCGCGAGCAGGTGCCCCTGACCGAATGCCTGAAGGACACCGTCGCA
CGCGTCATGCCGCTGTGGGAAGAATCGATTGCACCGGCCATCAAGAGCGGCAAGCGCGTGGTGATCGCCGCGCACGGCAA
CAGCATTCGCGCGCTGGTGAAGTACCTGGACGGCATCTCCGACGCGGACATCGTCGGCCTGAACATTCCCAACGGCACGC
CGCTTGTGTATGAGCTGGACGCCAACCTCAAGCCGATCCGCCATTACTACCTGGGCGACCAGGAAGCGATTGCCGCGTCG
CTCGCGGCGGTGGCCAGCCAAGGCAAGTCGAAATAA

Upstream 100 bases:

>100_bases
GCCCAATGCCCGCGGCATTATAAAATAGTCGGTTTCAGCGGCTGCACGATGACGTACGACACGTCGCCACAGCCCCGCGC
AGGTTTTCTCACTTCTCATC

Downstream 100 bases:

>100_bases
ACCGTAACGGGCGCTGCGGCACTCCAACGCCTTTATACTGTCGAAGCCTGTAGCCCGGGATGTGCGCGAGCCGTCCCGGG
CCATGTTTATCTACTGTTCC

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM [H]

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MAVMHKLVLIRHGESTWNLENRFTGWVDVDLTDTGVAQARQGGKLLREAGFTFDLAYTSVLKRAIRTLWHVQDEMDLMWI
PTRNEWRLNERHYGALSGLNKAETAAQYGDEQVLVWRRSYDTPPPALEPGADNDAFGNPRYAGLTREQVPLTECLKDTVA
RVMPLWEESIAPAIKSGKRVVIAAHGNSIRALVKYLDGISDADIVGLNIPNGTPLVYELDANLKPIRHYYLGDQEAIAAS
LAAVASQGKSK

Sequences:

>Translated_251_residues
MAVMHKLVLIRHGESTWNLENRFTGWVDVDLTDTGVAQARQGGKLLREAGFTFDLAYTSVLKRAIRTLWHVQDEMDLMWI
PTRNEWRLNERHYGALSGLNKAETAAQYGDEQVLVWRRSYDTPPPALEPGADNDAFGNPRYAGLTREQVPLTECLKDTVA
RVMPLWEESIAPAIKSGKRVVIAAHGNSIRALVKYLDGISDADIVGLNIPNGTPLVYELDANLKPIRHYYLGDQEAIAAS
LAAVASQGKSK
>Mature_250_residues
AVMHKLVLIRHGESTWNLENRFTGWVDVDLTDTGVAQARQGGKLLREAGFTFDLAYTSVLKRAIRTLWHVQDEMDLMWIP
TRNEWRLNERHYGALSGLNKAETAAQYGDEQVLVWRRSYDTPPPALEPGADNDAFGNPRYAGLTREQVPLTECLKDTVAR
VMPLWEESIAPAIKSGKRVVIAAHGNSIRALVKYLDGISDADIVGLNIPNGTPLVYELDANLKPIRHYYLGDQEAIAASL
AAVASQGKSK

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate [H]

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily [H]

Homologues:

Organism=Homo sapiens, GI50593010, Length=250, Percent_Identity=55.2, Blast_Score=301, Evalue=3e-82,
Organism=Homo sapiens, GI4505753, Length=250, Percent_Identity=58.8, Blast_Score=299, Evalue=2e-81,
Organism=Homo sapiens, GI71274132, Length=250, Percent_Identity=56.8, Blast_Score=287, Evalue=7e-78,
Organism=Homo sapiens, GI4502445, Length=252, Percent_Identity=47.6190476190476, Blast_Score=256, Evalue=1e-68,
Organism=Homo sapiens, GI40353764, Length=252, Percent_Identity=47.6190476190476, Blast_Score=256, Evalue=1e-68,
Organism=Homo sapiens, GI310129614, Length=162, Percent_Identity=59.8765432098765, Blast_Score=194, Evalue=6e-50,
Organism=Escherichia coli, GI1786970, Length=251, Percent_Identity=61.3545816733068, Blast_Score=315, Evalue=1e-87,
Organism=Saccharomyces cerevisiae, GI6322697, Length=246, Percent_Identity=51.219512195122, Blast_Score=238, Evalue=8e-64,
Organism=Saccharomyces cerevisiae, GI6324516, Length=296, Percent_Identity=33.7837837837838, Blast_Score=143, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6320183, Length=296, Percent_Identity=32.7702702702703, Blast_Score=136, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24646216, Length=253, Percent_Identity=49.4071146245059, Blast_Score=256, Evalue=1e-68,
Organism=Drosophila melanogaster, GI85725270, Length=255, Percent_Identity=50.1960784313725, Blast_Score=247, Evalue=5e-66,
Organism=Drosophila melanogaster, GI85725272, Length=255, Percent_Identity=50.1960784313725, Blast_Score=247, Evalue=5e-66,
Organism=Drosophila melanogaster, GI24650981, Length=255, Percent_Identity=50.1960784313725, Blast_Score=247, Evalue=5e-66,
Organism=Drosophila melanogaster, GI28571817, Length=255, Percent_Identity=39.2156862745098, Blast_Score=181, Evalue=5e-46,
Organism=Drosophila melanogaster, GI28571815, Length=255, Percent_Identity=39.2156862745098, Blast_Score=181, Evalue=5e-46,
Organism=Drosophila melanogaster, GI24648979, Length=255, Percent_Identity=39.2156862745098, Blast_Score=180, Evalue=7e-46,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 27895; Mature: 27764

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00175 PG_MUTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVMHKLVLIRHGESTWNLENRFTGWVDVDLTDTGVAQARQGGKLLREAGFTFDLAYTSV
CHHHHEEEEEECCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCEEEHHHHHH
LKRAIRTLWHVQDEMDLMWIPTRNEWRLNERHYGALSGLNKAETAAQYGDEQVLVWRRSY
HHHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHCCCHHHHHHHCCCCEEEEEEECC
DTPPPALEPGADNDAFGNPRYAGLTREQVPLTECLKDTVARVMPLWEESIAPAIKSGKRV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
VIAAHGNSIRALVKYLDGISDADIVGLNIPNGTPLVYELDANLKPIRHYYLGDQEAIAAS
EEEECCCHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEECCCCCHHHHHHCCCHHHHHHH
LAAVASQGKSK
HHHHHHCCCCC
>Mature Secondary Structure 
AVMHKLVLIRHGESTWNLENRFTGWVDVDLTDTGVAQARQGGKLLREAGFTFDLAYTSV
HHHHEEEEEECCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCEEEHHHHHH
LKRAIRTLWHVQDEMDLMWIPTRNEWRLNERHYGALSGLNKAETAAQYGDEQVLVWRRSY
HHHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHCCCHHHHHHHCCCCEEEEEEECC
DTPPPALEPGADNDAFGNPRYAGLTREQVPLTECLKDTVARVMPLWEESIAPAIKSGKRV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
VIAAHGNSIRALVKYLDGISDADIVGLNIPNGTPLVYELDANLKPIRHYYLGDQEAIAAS
EEEECCCHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEECCCCCHHHHHHCCCHHHHHHH
LAAVASQGKSK
HHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]