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The map label for this gene is coaD

Identifier: 187918558

GI number: 187918558

Start: 747004

End: 747501

Strand: Direct

Name: coaD

Synonym: BH0702

Alternate gene names: 187918558

Gene position: 747004-747501 (Clockwise)

Preceding gene: 187918557

Following gene: 187918559

Centisome position: 80.99

GC content: 29.12

Gene sequence:

>498_bases
ATGAGAGTAGCATTATTTCCTGGTTCATTCGATCCTGTTACTTGGGGACATATTGATTTAGTGAAGAGAGCATCATTAAT
TTTTGATAAGGTTATTGTTCTTGTTGCTAATAATAGTGCTAAGAATTATTTGCTTAGTGATGTTGAGAGATATGAGCTTA
CTTTTGAGGTTATTGCGTCTTTAGGATGGTCAAAAATTTTTGTGGATAGGTATGATGGGATTATTTTGGATTATGCTTTA
AAGAATGATATTGGTTTTATTGTTAGAGGAGTTAGAGCTTTTCATGATTTTGAATTTGAATTTGAAAGGTATGTTGTTAA
TAACAAGCTTAGTCCTTTAGTAGACACAATATTTTTACCAAGTAGTGATAGATATCTGTTTGTAAGGTCAGATCTTGTTA
AAGAATTGATAAAGAATAAAAATTTTGATCTCTCAAGTTTTATTCCAGAGTTAGTGCAAAAAAAGTTGAAATCTAAATTT
ATTGACAAATTATCTTAA

Upstream 100 bases:

>100_bases
AAATAGTTAAAGAGATTGATTTTGAAAATTTAGAGAGTCGTCCTATTTGGCGAAAAAAAATTCTTCAAGATATGAATAAA
GGGTTTAAGTTTTATTAATT

Downstream 100 bases:

>100_bases
TAATATATATATTATTAAGATATGTTTGTTTATGTTTAAGGAGGCAAAAAGATGGCTGTTCCAAAATTTAAGCCTTCAAA
GTCTAGAAGTAGGACGAGGC

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 165; Mature: 165

Protein sequence:

>165_residues
MRVALFPGSFDPVTWGHIDLVKRASLIFDKVIVLVANNSAKNYLLSDVERYELTFEVIASLGWSKIFVDRYDGIILDYAL
KNDIGFIVRGVRAFHDFEFEFERYVVNNKLSPLVDTIFLPSSDRYLFVRSDLVKELIKNKNFDLSSFIPELVQKKLKSKF
IDKLS

Sequences:

>Translated_165_residues
MRVALFPGSFDPVTWGHIDLVKRASLIFDKVIVLVANNSAKNYLLSDVERYELTFEVIASLGWSKIFVDRYDGIILDYAL
KNDIGFIVRGVRAFHDFEFEFERYVVNNKLSPLVDTIFLPSSDRYLFVRSDLVKELIKNKNFDLSSFIPELVQKKLKSKF
IDKLS
>Mature_165_residues
MRVALFPGSFDPVTWGHIDLVKRASLIFDKVIVLVANNSAKNYLLSDVERYELTFEVIASLGWSKIFVDRYDGIILDYAL
KNDIGFIVRGVRAFHDFEFEFERYVVNNKLSPLVDTIFLPSSDRYLFVRSDLVKELIKNKNFDLSSFIPELVQKKLKSKF
IDKLS

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=157, Percent_Identity=35.031847133758, Blast_Score=110, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_BORHD (B2S145)

Other databases:

- EMBL:   CP000048
- RefSeq:   YP_001884121.1
- ProteinModelPortal:   B2S145
- EnsemblBacteria:   EBBORT00000006634
- GeneID:   6276485
- GenomeReviews:   CP000048_GR
- KEGG:   bhr:BH0702
- GeneTree:   EBGT00050000007240
- HOGENOM:   HBG288308
- OMA:   MDHARER
- ProtClustDB:   PRK00168
- BioCyc:   BHER314723:BH0702-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 19135; Mature: 19135

Theoretical pI: Translated: 8.78; Mature: 8.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVALFPGSFDPVTWGHIDLVKRASLIFDKVIVLVANNSAKNYLLSDVERYELTFEVIAS
CEEEECCCCCCCCCCCHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
LGWSKIFVDRYDGIILDYALKNDIGFIVRGVRAFHDFEFEFERYVVNNKLSPLVDTIFLP
CCHHHEEHCCCCCEEEEEHHHCCHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHEECC
SSDRYLFVRSDLVKELIKNKNFDLSSFIPELVQKKLKSKFIDKLS
CCCCEEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRVALFPGSFDPVTWGHIDLVKRASLIFDKVIVLVANNSAKNYLLSDVERYELTFEVIAS
CEEEECCCCCCCCCCCHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
LGWSKIFVDRYDGIILDYALKNDIGFIVRGVRAFHDFEFEFERYVVNNKLSPLVDTIFLP
CCHHHEEHCCCCCEEEEEHHHCCHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHEECC
SSDRYLFVRSDLVKELIKNKNFDLSSFIPELVQKKLKSKFIDKLS
CCCCEEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA