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The map label for this gene is mvk [H]

Identifier: 187918544

GI number: 187918544

Start: 735625

End: 736518

Strand: Direct

Name: mvk [H]

Synonym: BH0688

Alternate gene names: 187918544

Gene position: 735625-736518 (Clockwise)

Preceding gene: 187918543

Following gene: 187918546

Centisome position: 79.76

GC content: 29.98

Gene sequence:

>894_bases
ATGTTTATAATAAAAAAACCTTCTAAAATATTATTCTTAGGCGAACATAGTGCCGTTTATGGTTTTCCAGTAATTGGTGC
TACGATACCTCTTTATATGCACTTAGTTTATACCTTTTCTGCTTCTTGGAGGTACTTGGGAGTACCTTTTTTAAAAATAG
ATGAGGTAATACATTTTATTAATAAAAGGTTTAATAAAGTTAGGCCCATTGAATTTTTAATTTTTTCTCAAATTCCAGTT
GGACTGGGATTTGGTTCTTCTGCCAGTCTTAGTTTATGTTTTGCTGAATATATTGTAAGTCATGATGAATATAGTACTTA
CGATAAAATTTTGCTGGCAAGGGAAATTGAAAATATTTTTCATGGCAGGTCTTCTGGTATGGACGTTTTGCTTGTTGAGT
TAGATGGAACTTTTTATTTAGAGAGTCGAAATGGTGCTTTAAGTTATCTAAGAATATCATTTTGTAATTTTTACTTTTTA
ATTGGAGCAGTTAGAAGGGAATGTGCAACAAATGAAATAATATCTGATTTGAGCTATAGGATTTCTCTTGATAATGATCA
ATTTGAAATTATTAAAAAACTTGGTTGGATTGCTAGGGATTCTTATGTTGCTTTTGAGAAACGAGATATTGCTTTATTGG
CGAATAATATGAATGTTGCAAATAATTGTTTAAATTCTTTGGGTTTATCTTCAGGTGTACTTGATTATGTAATAGAGAGA
GGTAGAAAATTTAAGGCTCTTGCTGGTAAATTGAGTGGTGCTGGTAGGGGTGGGGCTTTTATTTTACTTTTTCAAAATAA
GAATGAAGCTAGCTTGTGTTTAGAGGAATTGAATAAGGATTTAGATAAGAATAATATTGATTTGATTTTTAAACTTAAAA
TATTTAAGTGTTAA

Upstream 100 bases:

>100_bases
AAATGAAACTTTTTTAGTTTATAAGCCGAATTTTGAAGTTTTTAAACAATTTAATATTGAACCAATAAATCTAGATTTAG
ATGGTGTTAAATTTCAGTAG

Downstream 100 bases:

>100_bases
ACTATATTAAAGACATATTAGAGAGAAATGTTTTTGTGAGGCTAAGGAATTGCATTTTATGTAGTGTCTTATAGTAACTT
AAAGAAAATTAATAAAATTA

Product: mevalonate kinase

Products: NA

Alternate protein names: MK [H]

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MFIIKKPSKILFLGEHSAVYGFPVIGATIPLYMHLVYTFSASWRYLGVPFLKIDEVIHFINKRFNKVRPIEFLIFSQIPV
GLGFGSSASLSLCFAEYIVSHDEYSTYDKILLAREIENIFHGRSSGMDVLLVELDGTFYLESRNGALSYLRISFCNFYFL
IGAVRRECATNEIISDLSYRISLDNDQFEIIKKLGWIARDSYVAFEKRDIALLANNMNVANNCLNSLGLSSGVLDYVIER
GRKFKALAGKLSGAGRGGAFILLFQNKNEASLCLEELNKDLDKNNIDLIFKLKIFKC

Sequences:

>Translated_297_residues
MFIIKKPSKILFLGEHSAVYGFPVIGATIPLYMHLVYTFSASWRYLGVPFLKIDEVIHFINKRFNKVRPIEFLIFSQIPV
GLGFGSSASLSLCFAEYIVSHDEYSTYDKILLAREIENIFHGRSSGMDVLLVELDGTFYLESRNGALSYLRISFCNFYFL
IGAVRRECATNEIISDLSYRISLDNDQFEIIKKLGWIARDSYVAFEKRDIALLANNMNVANNCLNSLGLSSGVLDYVIER
GRKFKALAGKLSGAGRGGAFILLFQNKNEASLCLEELNKDLDKNNIDLIFKLKIFKC
>Mature_297_residues
MFIIKKPSKILFLGEHSAVYGFPVIGATIPLYMHLVYTFSASWRYLGVPFLKIDEVIHFINKRFNKVRPIEFLIFSQIPV
GLGFGSSASLSLCFAEYIVSHDEYSTYDKILLAREIENIFHGRSSGMDVLLVELDGTFYLESRNGALSYLRISFCNFYFL
IGAVRRECATNEIISDLSYRISLDNDQFEIIKKLGWIARDSYVAFEKRDIALLANNMNVANNCLNSLGLSSGVLDYVIER
GRKFKALAGKLSGAGRGGAFILLFQNKNEASLCLEELNKDLDKNNIDLIFKLKIFKC

Specific function: Unknown

COG id: COG1577

COG function: function code I; Mevalonate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GHMP kinase family. Mevalonate kinase subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006204
- InterPro:   IPR013750
- InterPro:   IPR006203
- InterPro:   IPR006205
- InterPro:   IPR006206
- InterPro:   IPR022937
- InterPro:   IPR020568
- InterPro:   IPR014721 [H]

Pfam domain/function: PF08544 GHMP_kinases_C; PF00288 GHMP_kinases_N [H]

EC number: =2.7.1.36 [H]

Molecular weight: Translated: 33632; Mature: 33632

Theoretical pI: Translated: 8.34; Mature: 8.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFIIKKPSKILFLGEHSAVYGFPVIGATIPLYMHLVYTFSASWRYLGVPFLKIDEVIHFI
CEEEECCCEEEEEECCCCEECCHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHH
NKRFNKVRPIEFLIFSQIPVGLGFGSSASLSLCFAEYIVSHDEYSTYDKILLAREIENIF
HHHHCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
HGRSSGMDVLLVELDGTFYLESRNGALSYLRISFCNFYFLIGAVRRECATNEIISDLSYR
CCCCCCCEEEEEEECCEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEE
ISLDNDQFEIIKKLGWIARDSYVAFEKRDIALLANNMNVANNCLNSLGLSSGVLDYVIER
EEECCCHHHHHHHHCCHHCCCEEEEECCCEEEEECCCCHHHHHHHHCCCCCHHHHHHHHC
GRKFKALAGKLSGAGRGGAFILLFQNKNEASLCLEELNKDLDKNNIDLIFKLKIFKC
CCHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHCCCCCCEEEEEEEEECC
>Mature Secondary Structure
MFIIKKPSKILFLGEHSAVYGFPVIGATIPLYMHLVYTFSASWRYLGVPFLKIDEVIHFI
CEEEECCCEEEEEECCCCEECCHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHH
NKRFNKVRPIEFLIFSQIPVGLGFGSSASLSLCFAEYIVSHDEYSTYDKILLAREIENIF
HHHHCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
HGRSSGMDVLLVELDGTFYLESRNGALSYLRISFCNFYFLIGAVRRECATNEIISDLSYR
CCCCCCCEEEEEEECCEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEE
ISLDNDQFEIIKKLGWIARDSYVAFEKRDIALLANNMNVANNCLNSLGLSSGVLDYVIER
EEECCCHHHHHHHHCCHHCCCEEEEECCCEEEEECCCCHHHHHHHHCCCCCHHHHHHHHC
GRKFKALAGKLSGAGRGGAFILLFQNKNEASLCLEELNKDLDKNNIDLIFKLKIFKC
CCHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHCCCCCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA