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The map label for this gene is gpmA [H]

Identifier: 187918514

GI number: 187918514

Start: 703816

End: 704562

Strand: Direct

Name: gpmA [H]

Synonym: BH0658

Alternate gene names: 187918514

Gene position: 703816-704562 (Clockwise)

Preceding gene: 187918512

Following gene: 187918517

Centisome position: 76.31

GC content: 34.14

Gene sequence:

>747_bases
ATGTATAAATTAGTTTTAGTGAGGCATGGTGAGAGTGAATGGAATAGAGAAAATCTTTTTACAGGCTGGACTGATGTTAA
GCTTTCTGAAAAGGGTATTTCTGAAGCTTTAGAGGGTGGTAGAGTTCTTAAACAAAATGGATATTCTTTTGATATTGCTT
TTAGTTCAATGTTAGTCAGAGCTAATGATACTTTAAATATTATTTTGCGTGAGTTGGGACAATCTTATATTGATGTAGAG
AAATCCTGGCGACTCAATGAGAGGCATTATGGAGCTTTGCAAGGGTTAAATAAGGCTGAGACAGCTGAGAAGTATGGAGA
AGATCAGGTTTTAATGTGGAGACGTAGTTATGATATTCCTCCTATGCCTTTAGAAGAGTCTGATAAGCGTCATCCAATTC
ATGACTTAAGATATAAAGGAATTCCTAAAAGTGAGCTTCCCTCAACAGAATGTTTAAAGGATACTGTTGCAAGAGTTATA
CCGTATTGGACAGATAAAATTGCTAAAGCTATTATTGAGGGAAAAAGAGTTATTATTGCTGCTCATGGTAATTCCTTAAG
AGCTCTTGTTAAATATCTTGATAATATGAGTGATGATGATATTTTAAAGCTCAATATTCCGACTGGTATTCCTTTAGTTT
ATGAACTTGATCAAGATTTAAGACCTATTAAACACTATTACTTAGGTGATGAGGATAAGATTAAGGCGGCTATGGAATCT
GTTGCTAATCAAGGAAAGAAAAAATAA

Upstream 100 bases:

>100_bases
CTTGGGGGGGATTCTTGAGTATTAACATTAATTAGATTTTGTGTTAATTTAATTGATAAAATGTTATTAAAGTAATAAAA
AACATTTCTTAGGAGATTTT

Downstream 100 bases:

>100_bases
AGAGGCCATTAAGACTATTAGGAAGAGATCATTTAAGTTAATGCTCTCTTCCTGTTATATGTTAAATAATTTAATATTGG
AGCTAAATATAGTGTTTAAC

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM [H]

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MYKLVLVRHGESEWNRENLFTGWTDVKLSEKGISEALEGGRVLKQNGYSFDIAFSSMLVRANDTLNIILRELGQSYIDVE
KSWRLNERHYGALQGLNKAETAEKYGEDQVLMWRRSYDIPPMPLEESDKRHPIHDLRYKGIPKSELPSTECLKDTVARVI
PYWTDKIAKAIIEGKRVIIAAHGNSLRALVKYLDNMSDDDILKLNIPTGIPLVYELDQDLRPIKHYYLGDEDKIKAAMES
VANQGKKK

Sequences:

>Translated_248_residues
MYKLVLVRHGESEWNRENLFTGWTDVKLSEKGISEALEGGRVLKQNGYSFDIAFSSMLVRANDTLNIILRELGQSYIDVE
KSWRLNERHYGALQGLNKAETAEKYGEDQVLMWRRSYDIPPMPLEESDKRHPIHDLRYKGIPKSELPSTECLKDTVARVI
PYWTDKIAKAIIEGKRVIIAAHGNSLRALVKYLDNMSDDDILKLNIPTGIPLVYELDQDLRPIKHYYLGDEDKIKAAMES
VANQGKKK
>Mature_248_residues
MYKLVLVRHGESEWNRENLFTGWTDVKLSEKGISEALEGGRVLKQNGYSFDIAFSSMLVRANDTLNIILRELGQSYIDVE
KSWRLNERHYGALQGLNKAETAEKYGEDQVLMWRRSYDIPPMPLEESDKRHPIHDLRYKGIPKSELPSTECLKDTVARVI
PYWTDKIAKAIIEGKRVIIAAHGNSLRALVKYLDNMSDDDILKLNIPTGIPLVYELDQDLRPIKHYYLGDEDKIKAAMES
VANQGKKK

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate [H]

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily [H]

Homologues:

Organism=Homo sapiens, GI50593010, Length=253, Percent_Identity=54.1501976284585, Blast_Score=284, Evalue=6e-77,
Organism=Homo sapiens, GI4505753, Length=250, Percent_Identity=55.2, Blast_Score=271, Evalue=3e-73,
Organism=Homo sapiens, GI4502445, Length=255, Percent_Identity=48.6274509803922, Blast_Score=261, Evalue=6e-70,
Organism=Homo sapiens, GI40353764, Length=255, Percent_Identity=48.6274509803922, Blast_Score=261, Evalue=6e-70,
Organism=Homo sapiens, GI71274132, Length=250, Percent_Identity=52, Blast_Score=253, Evalue=2e-67,
Organism=Homo sapiens, GI310129614, Length=162, Percent_Identity=53.7037037037037, Blast_Score=165, Evalue=4e-41,
Organism=Escherichia coli, GI1786970, Length=246, Percent_Identity=63.0081300813008, Blast_Score=317, Evalue=7e-88,
Organism=Saccharomyces cerevisiae, GI6322697, Length=247, Percent_Identity=54.251012145749, Blast_Score=258, Evalue=8e-70,
Organism=Saccharomyces cerevisiae, GI6324516, Length=296, Percent_Identity=33.7837837837838, Blast_Score=157, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6320183, Length=296, Percent_Identity=32.4324324324324, Blast_Score=145, Evalue=7e-36,
Organism=Drosophila melanogaster, GI24646216, Length=251, Percent_Identity=53.7848605577689, Blast_Score=279, Evalue=1e-75,
Organism=Drosophila melanogaster, GI85725270, Length=251, Percent_Identity=55.3784860557769, Blast_Score=273, Evalue=1e-73,
Organism=Drosophila melanogaster, GI85725272, Length=251, Percent_Identity=55.3784860557769, Blast_Score=273, Evalue=1e-73,
Organism=Drosophila melanogaster, GI24650981, Length=251, Percent_Identity=55.3784860557769, Blast_Score=273, Evalue=1e-73,
Organism=Drosophila melanogaster, GI28571815, Length=252, Percent_Identity=39.2857142857143, Blast_Score=185, Evalue=2e-47,
Organism=Drosophila melanogaster, GI28571817, Length=252, Percent_Identity=39.2857142857143, Blast_Score=185, Evalue=3e-47,
Organism=Drosophila melanogaster, GI24648979, Length=252, Percent_Identity=39.2857142857143, Blast_Score=185, Evalue=3e-47,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 28462; Mature: 28462

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: PS00175 PG_MUTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKLVLVRHGESEWNRENLFTGWTDVKLSEKGISEALEGGRVLKQNGYSFDIAFSSMLVR
CEEEEEEECCCCCCCCCCCCCCCCCCEECHHHHHHHHHCCEEEECCCCEEEEEHHHHHHC
ANDTLNIILRELGQSYIDVEKSWRLNERHYGALQGLNKAETAEKYGEDQVLMWRRSYDIP
CCCHHHHHHHHHCHHHHCHHHHCCCCCHHHHHHHCCCHHHHHHHHCCCEEEEEEECCCCC
PMPLEESDKRHPIHDLRYKGIPKSELPSTECLKDTVARVIPYWTDKIAKAIIEGKRVIIA
CCCCCCCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEE
AHGNSLRALVKYLDNMSDDDILKLNIPTGIPLVYELDQDLRPIKHYYLGDEDKIKAAMES
ECCCHHHHHHHHHHCCCCCCEEEEECCCCCCEEEECCHHHHHHHHHHCCCHHHHHHHHHH
VANQGKKK
HHHCCCCC
>Mature Secondary Structure
MYKLVLVRHGESEWNRENLFTGWTDVKLSEKGISEALEGGRVLKQNGYSFDIAFSSMLVR
CEEEEEEECCCCCCCCCCCCCCCCCCEECHHHHHHHHHCCEEEECCCCEEEEEHHHHHHC
ANDTLNIILRELGQSYIDVEKSWRLNERHYGALQGLNKAETAEKYGEDQVLMWRRSYDIP
CCCHHHHHHHHHCHHHHCHHHHCCCCCHHHHHHHCCCHHHHHHHHCCCEEEEEEECCCCC
PMPLEESDKRHPIHDLRYKGIPKSELPSTECLKDTVARVIPYWTDKIAKAIIEGKRVIIA
CCCCCCCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEE
AHGNSLRALVKYLDNMSDDDILKLNIPTGIPLVYELDQDLRPIKHYYLGDEDKIKAAMES
ECCCHHHHHHHHHHCCCCCCEEEEECCCCCCEEEECCHHHHHHHHHHCCCHHHHHHHHHH
VANQGKKK
HHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA