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The map label for this gene is yajL [H]

Identifier: 187918480

GI number: 187918480

Start: 655486

End: 656031

Strand: Direct

Name: yajL [H]

Synonym: BH0621

Alternate gene names: 187918480

Gene position: 655486-656031 (Clockwise)

Preceding gene: 187918478

Following gene: 187918483

Centisome position: 71.07

GC content: 35.9

Gene sequence:

>546_bases
ATGAGAGCTGCAATTGTGCTTGCCAATGGTTTTGAAGAGATTGAAGCTGTAGTCCCTATGGATATTTTAAGACGTGGTGG
TGTTGATCTGAAGGTTATTGGTTTAAATGATGATAGGGTTGTTTTAAGTTCTAGAGGATTTACTTTTTGGACTGATAAGA
AAATATCAGATTGTAGTGCAGATCATTTTGATTTAATAATACTTCCTGGAGGAATGCCTGGTGCTACAAATCTTTTTGAA
TCGCAAAATTTAGATAAGATTTTAAGAAATATGAACTTACAAGGTAAGTTGATTGCAGCCATTTGTGCATCACCAGCAGT
TGTGCTTTCTGCAAAGGGACTTTTGGGGACAAATAAGTTTACGTGCTATCCAGGCTTTGAAAATGGTATTACTGATGGTG
AATTTGTGGATGATGATGTTGTTGTTAGTAATAATTTCATTACTTCTAAGGGTGTTGGCACGGCTTTCAAGTTTGCTTTT
ACTTTGCTTAAGATTATTAAGGGAGAGAGCGTACTTGAGGATGTTAAGAGGAAAGCTTTGCTTTAA

Upstream 100 bases:

>100_bases
ATGGCTGCAAGCTGATGTAGCTCAGTTGGTTAGAGCACTCGGCTCATATCCGAGTTGTCGTGGGTTCAAGTCCCTCCATC
AGCATTAAGGAGTTTGTGTT

Downstream 100 bases:

>100_bases
TATGATTTGTACTACAGGATATTTCAGTTAATTTAGTAAGTCAGTTCTTAAAGATTGCCTTATAATAATTTAAATTTTTT
AATTTATTTTAAATCCCGTG

Product: 4-methyl-5(B-hydroxyethyl)-thiazole monophosphate biosynthesis enzyme

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 181; Mature: 181

Protein sequence:

>181_residues
MRAAIVLANGFEEIEAVVPMDILRRGGVDLKVIGLNDDRVVLSSRGFTFWTDKKISDCSADHFDLIILPGGMPGATNLFE
SQNLDKILRNMNLQGKLIAAICASPAVVLSAKGLLGTNKFTCYPGFENGITDGEFVDDDVVVSNNFITSKGVGTAFKFAF
TLLKIIKGESVLEDVKRKALL

Sequences:

>Translated_181_residues
MRAAIVLANGFEEIEAVVPMDILRRGGVDLKVIGLNDDRVVLSSRGFTFWTDKKISDCSADHFDLIILPGGMPGATNLFE
SQNLDKILRNMNLQGKLIAAICASPAVVLSAKGLLGTNKFTCYPGFENGITDGEFVDDDVVVSNNFITSKGVGTAFKFAF
TLLKIIKGESVLEDVKRKALL
>Mature_181_residues
MRAAIVLANGFEEIEAVVPMDILRRGGVDLKVIGLNDDRVVLSSRGFTFWTDKKISDCSADHFDLIILPGGMPGATNLFE
SQNLDKILRNMNLQGKLIAAICASPAVVLSAKGLLGTNKFTCYPGFENGITDGEFVDDDVVVSNNFITSKGVGTAFKFAF
TLLKIIKGESVLEDVKRKALL

Specific function: Involved in biogenesis of ribosomal proteins, probably as a ribosomal protein-folding chaperone. Interacts with ribosomal subunits, ribosomes and polysomes. Confers resistance to oxidative stress [H]

COG id: COG0693

COG function: function code R; Putative intracellular protease/amidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C56 family [H]

Homologues:

Organism=Homo sapiens, GI183227678, Length=184, Percent_Identity=34.2391304347826, Blast_Score=108, Evalue=2e-24,
Organism=Homo sapiens, GI31543380, Length=184, Percent_Identity=34.2391304347826, Blast_Score=108, Evalue=2e-24,
Organism=Escherichia coli, GI87081736, Length=183, Percent_Identity=29.5081967213115, Blast_Score=95, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17531319, Length=167, Percent_Identity=35.9281437125749, Blast_Score=110, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI17558714, Length=159, Percent_Identity=37.7358490566038, Blast_Score=101, Evalue=3e-22,
Organism=Drosophila melanogaster, GI28571932, Length=181, Percent_Identity=35.9116022099448, Blast_Score=121, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24653499, Length=181, Percent_Identity=34.2541436464088, Blast_Score=100, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006287
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: NA

Molecular weight: Translated: 19571; Mature: 19571

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAAIVLANGFEEIEAVVPMDILRRGGVDLKVIGLNDDRVVLSSRGFTFWTDKKISDCSA
CCEEEEEECCHHHHHHHCCHHHHHCCCCCEEEEECCCCEEEEECCCEEEEECCCCCCCCC
DHFDLIILPGGMPGATNLFESQNLDKILRNMNLQGKLIAAICASPAVVLSAKGLLGTNKF
CCEEEEEECCCCCCCCHHHCCCCHHHHHHCCCCCCHHHEEHHCCCEEEEEECCCCCCCEE
TCYPGFENGITDGEFVDDDVVVSNNFITSKGVGTAFKFAFTLLKIIKGESVLEDVKRKAL
EEECCCCCCCCCCCCCCCCEEEECCEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHC
L
C
>Mature Secondary Structure
MRAAIVLANGFEEIEAVVPMDILRRGGVDLKVIGLNDDRVVLSSRGFTFWTDKKISDCSA
CCEEEEEECCHHHHHHHCCHHHHHCCCCCEEEEECCCCEEEEECCCEEEEECCCCCCCCC
DHFDLIILPGGMPGATNLFESQNLDKILRNMNLQGKLIAAICASPAVVLSAKGLLGTNKF
CCEEEEEECCCCCCCCHHHCCCCHHHHHHCCCCCCHHHEEHHCCCEEEEEECCCCCCCEE
TCYPGFENGITDGEFVDDDVVVSNNFITSKGVGTAFKFAFTLLKIIKGESVLEDVKRKAL
EEECCCCCCCCCCCCCCCCEEEECCEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHC
L
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503; 9592144 [H]