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The map label for this gene is clpX [H]

Identifier: 187918472

GI number: 187918472

Start: 645382

End: 646683

Strand: Direct

Name: clpX [H]

Synonym: BH0612

Alternate gene names: 187918472

Gene position: 645382-646683 (Clockwise)

Preceding gene: 187918471

Following gene: 187918473

Centisome position: 69.97

GC content: 32.87

Gene sequence:

>1302_bases
GTGAGATTTTATATGGCAAAAAGTAAAAGTCAAAAAATTGAAGGGTGTTCTTTTTGTGGGCGTACTAATGCTGAAGTTGA
AGGACGAATTATTTCAGCAAAGTCTGTTGCTATTTGTTTTGAATGTTCTAAAATATGTCATAATCTTTTTAAAGAAGATA
CAGAAAAACCTGAAAGGGGTAGATCTTCAAGATCCCTTCCAACCCCTAAGCAACTTAAAAGTCATTTAGATAAATATATT
ATTGGACAGGAAGATGCAAAGAAAGTATTGTCCGTTGCTGTTTATAATCACTATAAGAGGATATTTAGAGGTAACAAAAA
GGAGAGTGGAGTTGAACTTGAGAAATCTAATGTATTGCTTGTAGGTCCTACTGGGAGTGGTAAAACTTTACTTGCAAAAA
AGTTGGCAGATGAGATGAATGTTCCGTTTGCAATAGCGGATGCTACAACGCTTACTGAGGCTGGATATGTTGGAGAGGAT
GTTGAGAATATTTTACTTAAGTTGATTCATGCTGCTAATGGAGATGTGAGTTTTGCAGAAAGAGGTATTGTTTACATAGA
TGAAATAGATAAGATTGCAAAAAAAGGTGAAAATGTTTCAATTACAAGGGATGTATCTGGAGAAGGTGTGCAACAATCTT
TATTGAAAATAATTGAAGGCACTATTGCAAATATACCTCCAAAGGGTGGGAGAAAACATCCTTATGAGGAGACTATTGAA
ATCAATACGCAAGACATACTATTCATATGTGGTGGGGCGTTTGTGGGACTTGAAAATATTATTAAAAGAAGAATTAATAA
AAGTTCCATTGGCTTTTCATCTGTTGGTAAACAAGATTCAAGGGAAAATAATTCTTTAAAATACTTAGAAATGGAAGATT
TGGTTAAATTTGGACTCATTCCAGAATTTGTCGGTAGGCTTCCTGTACATTCTTATCTTGAGAAGCTAGAAAAGGAAGAT
TTAATTAAAATATTAATTGAACCTGAGAATTCTATCGTGAAACAATATTATCATATGTTTAAAATGGATAATGTTGAACT
GGTATTTGAAAGGGATGCGCTTAATGCAATTGCAGAAGAAGCCATGTTAAAAAATACAGGTGCTAGAGGTTTGCGTTCTA
TTTTAGAAGAATTACTTAAAGATGTGATGTTTGAGATACCTTCAACTAAGCAAATTAAAAAAGTTATTGTTACTAAAGAG
TCTGTTTTAAATAGCAATATTGAGCCCTTTATTTTGACAGGAAGGCATGTTCATAAGCCTTGGGCAAAAGAACTTTATGA
AATCAATTCTAAATCTAATTAA

Upstream 100 bases:

>100_bases
TATCTCTTGATATCGAGCGAGATTATTTTATGACACCAAAAGATGCTCTTGATTATGGCATTATTGATGGTATCTTGGTA
AGAAATTAGTTTTATTTTGG

Downstream 100 bases:

>100_bases
TTCTAAGAGAGATGATCTTCCAGTTATTCTCTTAAGACAAAATGTTTTTTTCCCCAATGTAACTTTATGGGTTAATTTTG
ATGATAGTGTTTCGATTAAT

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MRFYMAKSKSQKIEGCSFCGRTNAEVEGRIISAKSVAICFECSKICHNLFKEDTEKPERGRSSRSLPTPKQLKSHLDKYI
IGQEDAKKVLSVAVYNHYKRIFRGNKKESGVELEKSNVLLVGPTGSGKTLLAKKLADEMNVPFAIADATTLTEAGYVGED
VENILLKLIHAANGDVSFAERGIVYIDEIDKIAKKGENVSITRDVSGEGVQQSLLKIIEGTIANIPPKGGRKHPYEETIE
INTQDILFICGGAFVGLENIIKRRINKSSIGFSSVGKQDSRENNSLKYLEMEDLVKFGLIPEFVGRLPVHSYLEKLEKED
LIKILIEPENSIVKQYYHMFKMDNVELVFERDALNAIAEEAMLKNTGARGLRSILEELLKDVMFEIPSTKQIKKVIVTKE
SVLNSNIEPFILTGRHVHKPWAKELYEINSKSN

Sequences:

>Translated_433_residues
MRFYMAKSKSQKIEGCSFCGRTNAEVEGRIISAKSVAICFECSKICHNLFKEDTEKPERGRSSRSLPTPKQLKSHLDKYI
IGQEDAKKVLSVAVYNHYKRIFRGNKKESGVELEKSNVLLVGPTGSGKTLLAKKLADEMNVPFAIADATTLTEAGYVGED
VENILLKLIHAANGDVSFAERGIVYIDEIDKIAKKGENVSITRDVSGEGVQQSLLKIIEGTIANIPPKGGRKHPYEETIE
INTQDILFICGGAFVGLENIIKRRINKSSIGFSSVGKQDSRENNSLKYLEMEDLVKFGLIPEFVGRLPVHSYLEKLEKED
LIKILIEPENSIVKQYYHMFKMDNVELVFERDALNAIAEEAMLKNTGARGLRSILEELLKDVMFEIPSTKQIKKVIVTKE
SVLNSNIEPFILTGRHVHKPWAKELYEINSKSN
>Mature_433_residues
MRFYMAKSKSQKIEGCSFCGRTNAEVEGRIISAKSVAICFECSKICHNLFKEDTEKPERGRSSRSLPTPKQLKSHLDKYI
IGQEDAKKVLSVAVYNHYKRIFRGNKKESGVELEKSNVLLVGPTGSGKTLLAKKLADEMNVPFAIADATTLTEAGYVGED
VENILLKLIHAANGDVSFAERGIVYIDEIDKIAKKGENVSITRDVSGEGVQQSLLKIIEGTIANIPPKGGRKHPYEETIE
INTQDILFICGGAFVGLENIIKRRINKSSIGFSSVGKQDSRENNSLKYLEMEDLVKFGLIPEFVGRLPVHSYLEKLEKED
LIKILIEPENSIVKQYYHMFKMDNVELVFERDALNAIAEEAMLKNTGARGLRSILEELLKDVMFEIPSTKQIKKVIVTKE
SVLNSNIEPFILTGRHVHKPWAKELYEINSKSN

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=316, Percent_Identity=49.6835443037975, Blast_Score=285, Evalue=5e-77,
Organism=Escherichia coli, GI1786642, Length=422, Percent_Identity=54.0284360189574, Blast_Score=455, Evalue=1e-129,
Organism=Escherichia coli, GI1790366, Length=105, Percent_Identity=42.8571428571429, Blast_Score=92, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI71982905, Length=313, Percent_Identity=44.408945686901, Blast_Score=265, Evalue=2e-71,
Organism=Caenorhabditis elegans, GI71982908, Length=313, Percent_Identity=44.408945686901, Blast_Score=265, Evalue=3e-71,
Organism=Caenorhabditis elegans, GI71988663, Length=405, Percent_Identity=36.7901234567901, Blast_Score=246, Evalue=2e-65,
Organism=Caenorhabditis elegans, GI71988660, Length=250, Percent_Identity=37.6, Blast_Score=172, Evalue=4e-43,
Organism=Saccharomyces cerevisiae, GI6319704, Length=425, Percent_Identity=40.7058823529412, Blast_Score=269, Evalue=6e-73,
Organism=Drosophila melanogaster, GI24648291, Length=318, Percent_Identity=44.0251572327044, Blast_Score=275, Evalue=4e-74,
Organism=Drosophila melanogaster, GI24648289, Length=318, Percent_Identity=44.0251572327044, Blast_Score=275, Evalue=5e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 48567; Mature: 48567

Theoretical pI: Translated: 8.33; Mature: 8.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFYMAKSKSQKIEGCSFCGRTNAEVEGRIISAKSVAICFECSKICHNLFKEDTEKPERG
CCEECCCCCCCCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCC
RSSRSLPTPKQLKSHLDKYIIGQEDAKKVLSVAVYNHYKRIFRGNKKESGVELEKSNVLL
CCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCEEE
VGPTGSGKTLLAKKLADEMNVPFAIADATTLTEAGYVGEDVENILLKLIHAANGDVSFAE
EECCCCCHHHHHHHHHHHCCCCEEEECCHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHH
RGIVYIDEIDKIAKKGENVSITRDVSGEGVQQSLLKIIEGTIANIPPKGGRKHPYEETIE
CCCEEEHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHEE
INTQDILFICGGAFVGLENIIKRRINKSSIGFSSVGKQDSRENNSLKYLEMEDLVKFGLI
ECCCEEEEEECCHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCCEEEEEHHHHHHHCCC
PEFVGRLPVHSYLEKLEKEDLIKILIEPENSIVKQYYHMFKMDNVELVFERDALNAIAEE
HHHHHCCCHHHHHHHHCHHCEEEEEECCCHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHH
AMLKNTGARGLRSILEELLKDVMFEIPSTKQIKKVIVTKESVLNSNIEPFILTGRHVHKP
HHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCH
WAKELYEINSKSN
HHHHHHHHCCCCC
>Mature Secondary Structure
MRFYMAKSKSQKIEGCSFCGRTNAEVEGRIISAKSVAICFECSKICHNLFKEDTEKPERG
CCEECCCCCCCCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCC
RSSRSLPTPKQLKSHLDKYIIGQEDAKKVLSVAVYNHYKRIFRGNKKESGVELEKSNVLL
CCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCEEE
VGPTGSGKTLLAKKLADEMNVPFAIADATTLTEAGYVGEDVENILLKLIHAANGDVSFAE
EECCCCCHHHHHHHHHHHCCCCEEEECCHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHH
RGIVYIDEIDKIAKKGENVSITRDVSGEGVQQSLLKIIEGTIANIPPKGGRKHPYEETIE
CCCEEEHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHEE
INTQDILFICGGAFVGLENIIKRRINKSSIGFSSVGKQDSRENNSLKYLEMEDLVKFGLI
ECCCEEEEEECCHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCCEEEEEHHHHHHHCCC
PEFVGRLPVHSYLEKLEKEDLIKILIEPENSIVKQYYHMFKMDNVELVFERDALNAIAEE
HHHHHCCCHHHHHHHHCHHCEEEEEECCCHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHH
AMLKNTGARGLRSILEELLKDVMFEIPSTKQIKKVIVTKESVLNSNIEPFILTGRHVHKP
HHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCH
WAKELYEINSKSN
HHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA