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The map label for this gene is oxaA

Identifier: 187918308

GI number: 187918308

Start: 465008

End: 466645

Strand: Direct

Name: oxaA

Synonym: BH0442

Alternate gene names: 187918308

Gene position: 465008-466645 (Clockwise)

Preceding gene: 187918307

Following gene: 187918309

Centisome position: 50.42

GC content: 27.96

Gene sequence:

>1638_bases
GTGAGTCAGAGTAAAAGAATTTTAAGAGCCATTTATTTGTCTTTATTTTTTATCGGTATTTTTATGATTATTGATGATAT
CTTTTTCTCTCACAAATCTCCTTCTGTAATGGATAAGGAGATTGGATTTAACTTAGATAAAGATTTTGATATTGATAATT
CTTCAATTGATGAAGATTATGCTTTAAACTTGAGCGCTAATTCTAAAGACATTGATGTTGAGACTGGCATATATTATGCT
ACTTTTTCGACATTTAGGGGAGATTTAATTTCTCTAAAGCTTAAGGATCATTTAAATTTAGAGAAAGAACCAACAGAAAT
GGTTAAGGTTAATATGGATAGGGAGAGTCTTTTTTATGTTACCCTTGATAACTTAACTAGAGATTTATTTTCATACGACA
GAGTAGATGACTATACGCATGATTTTAAGACCAATTTTGAATATAATGGCAAGTTTTATGAGTACATAAAGAGATATACA
TTTTCAAACAAAGGCGAATATTTAATCAAGCTTGAAATCTTTTTAAATAATATTGATGCTAATGATAATTCTGATATTGA
TTCTTATAAGTTTGTATTAAGTTCTGATATTGAAAAGTTAAGCGAGAGAGGTAAGCTGCAATATAATAATTATTTATCTC
AAGCTGTTTATTTTGATACTAAGCTTAGATATGGTAAGGATGGTTTAAGTGTTATTAGTCCTAAGTGGGTTGGTTCGGGT
ACTAAATATTTTGAAGTTTTAGTTTCAAAAGAAAATATGAATGTTGAATTTAAACAGGAAAGTAAAATTTTAAAGGCTTT
TATTTTAAACAAAGTAGGTAATAAAAATATTAGTGATACCTTTTATATTTATGCAGGCCCTAAAGATAATGGATATTTAG
ATCTTTTTAATAAAGAGGATCTAAATAGTTTTGGTTTATCTAATGTTGAATTTGGAATGTCTGTAGAGAAGAGCTTGTTA
TACTTTATTCAAGTTCCTATGCAATTGATAATGCAAATTTTTTATAATGTTATTCCTAATTGGGGACTTTCAATAATGTT
TCTTACAATTGTTGTAAGAATACTTATATTTCCTTTGACTTTTAAAAGTTTTAGGGCTACAGCAGAACTTTCTAAATTAC
AGCCAAAAATGAAAGAGATACAAGTAAAATTTAAAAATGATCCTAAAAGGTTAAATGAAGAGATGGGTAAACTTTATAGG
GAAGAAGGAGTTAATCCTCTTGGAGGATGTTTTCCTATTCTTTTACAACTACCTGTATTTTTTGCTCTTTATGGCCTTGT
GAATAATTTCTTTTTGCTAAGGGGGGCTAGTTTTATTCCAGGCTGGATTGATGATTTGTCAATTGGTGATAGCATATATT
ATTTTGGGTATAAAGTTTTTATGTGGACTGATATTAGAATTTTACCTTTTATTATGATGGTTACTCAGTTAATCTCTACA
ATAATTAGTTCTAATGTTAGTTTTAAAAGTCTTGGATCACAACAGAAAATTTTATATTTTGGTATGCCCATTATGTTTTT
TTTCATACTGTATGATATGCCATCAGGACTTTTAATCTATTGGATTACAACCAATATTTTTACTATTTTGCAACAATACT
ATATAAAGATGAATGTATCTGAAAGGAGGAACAGATGA

Upstream 100 bases:

>100_bases
ACTTTATTTTCGTAGTTTATCCTCAAAAAGCAGATGTTAATTATCATGAAGTTGAGACGATACTAAAGAATATAGTTGTG
TATATCATGAAGAGGAATAT

Downstream 100 bases:

>100_bases
GTTATGAGTTTTATGGAAAAACAGAACAAGAAGCAATTAAAAAAGCTATGAGAGATCTTGATTTAAAAGAAGGCGAGTTT
GATGTAGAGATTTTGGATAA

Product: putative inner membrane protein translocase component YidC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 545; Mature: 544

Protein sequence:

>545_residues
MSQSKRILRAIYLSLFFIGIFMIIDDIFFSHKSPSVMDKEIGFNLDKDFDIDNSSIDEDYALNLSANSKDIDVETGIYYA
TFSTFRGDLISLKLKDHLNLEKEPTEMVKVNMDRESLFYVTLDNLTRDLFSYDRVDDYTHDFKTNFEYNGKFYEYIKRYT
FSNKGEYLIKLEIFLNNIDANDNSDIDSYKFVLSSDIEKLSERGKLQYNNYLSQAVYFDTKLRYGKDGLSVISPKWVGSG
TKYFEVLVSKENMNVEFKQESKILKAFILNKVGNKNISDTFYIYAGPKDNGYLDLFNKEDLNSFGLSNVEFGMSVEKSLL
YFIQVPMQLIMQIFYNVIPNWGLSIMFLTIVVRILIFPLTFKSFRATAELSKLQPKMKEIQVKFKNDPKRLNEEMGKLYR
EEGVNPLGGCFPILLQLPVFFALYGLVNNFFLLRGASFIPGWIDDLSIGDSIYYFGYKVFMWTDIRILPFIMMVTQLIST
IISSNVSFKSLGSQQKILYFGMPIMFFFILYDMPSGLLIYWITTNIFTILQQYYIKMNVSERRNR

Sequences:

>Translated_545_residues
MSQSKRILRAIYLSLFFIGIFMIIDDIFFSHKSPSVMDKEIGFNLDKDFDIDNSSIDEDYALNLSANSKDIDVETGIYYA
TFSTFRGDLISLKLKDHLNLEKEPTEMVKVNMDRESLFYVTLDNLTRDLFSYDRVDDYTHDFKTNFEYNGKFYEYIKRYT
FSNKGEYLIKLEIFLNNIDANDNSDIDSYKFVLSSDIEKLSERGKLQYNNYLSQAVYFDTKLRYGKDGLSVISPKWVGSG
TKYFEVLVSKENMNVEFKQESKILKAFILNKVGNKNISDTFYIYAGPKDNGYLDLFNKEDLNSFGLSNVEFGMSVEKSLL
YFIQVPMQLIMQIFYNVIPNWGLSIMFLTIVVRILIFPLTFKSFRATAELSKLQPKMKEIQVKFKNDPKRLNEEMGKLYR
EEGVNPLGGCFPILLQLPVFFALYGLVNNFFLLRGASFIPGWIDDLSIGDSIYYFGYKVFMWTDIRILPFIMMVTQLIST
IISSNVSFKSLGSQQKILYFGMPIMFFFILYDMPSGLLIYWITTNIFTILQQYYIKMNVSERRNR
>Mature_544_residues
SQSKRILRAIYLSLFFIGIFMIIDDIFFSHKSPSVMDKEIGFNLDKDFDIDNSSIDEDYALNLSANSKDIDVETGIYYAT
FSTFRGDLISLKLKDHLNLEKEPTEMVKVNMDRESLFYVTLDNLTRDLFSYDRVDDYTHDFKTNFEYNGKFYEYIKRYTF
SNKGEYLIKLEIFLNNIDANDNSDIDSYKFVLSSDIEKLSERGKLQYNNYLSQAVYFDTKLRYGKDGLSVISPKWVGSGT
KYFEVLVSKENMNVEFKQESKILKAFILNKVGNKNISDTFYIYAGPKDNGYLDLFNKEDLNSFGLSNVEFGMSVEKSLLY
FIQVPMQLIMQIFYNVIPNWGLSIMFLTIVVRILIFPLTFKSFRATAELSKLQPKMKEIQVKFKNDPKRLNEEMGKLYRE
EGVNPLGGCFPILLQLPVFFALYGLVNNFFLLRGASFIPGWIDDLSIGDSIYYFGYKVFMWTDIRILPFIMMVTQLISTI
ISSNVSFKSLGSQQKILYFGMPIMFFFILYDMPSGLLIYWITTNIFTILQQYYIKMNVSERRNR

Specific function: Required for the insertion of integral membrane proteins into the membrane. Probably plays an essential role in the integration of proteins of the respiratory chain complexes. Involved in integration of membrane proteins that insert dependently and indepe

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790140, Length=230, Percent_Identity=36.0869565217391, Blast_Score=149, Evalue=4e-37,
Organism=Drosophila melanogaster, GI24662345, Length=213, Percent_Identity=25.8215962441315, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21356443, Length=213, Percent_Identity=25.8215962441315, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OXAA_BORHD (B2S0E5)

Other databases:

- EMBL:   CP000048
- RefSeq:   YP_001883871.1
- EnsemblBacteria:   EBBORT00000006849
- GeneID:   6276525
- GenomeReviews:   CP000048_GR
- KEGG:   bhr:BH0442
- GeneTree:   EBGT00050000007198
- HOGENOM:   HBG352905
- OMA:   WITTNIF
- ProtClustDB:   PRK01318
- BioCyc:   BHER314723:BH0442-MONOMER
- HAMAP:   MF_01810
- InterPro:   IPR019998
- InterPro:   IPR001708
- PANTHER:   PTHR12428
- PRINTS:   PR00701
- PRINTS:   PR01900
- TIGRFAMs:   TIGR03592

Pfam domain/function: PF02096 60KD_IMP

EC number: NA

Molecular weight: Translated: 63667; Mature: 63536

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1eacb4c8)-; HASH(0x1ffc9678)-; HASH(0x1f59195c)-; HASH(0x1ffd0544)-; HASH(0x1f63f45c)-; HASH(0x1ffb6774)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQSKRILRAIYLSLFFIGIFMIIDDIFFSHKSPSVMDKEIGFNLDKDFDIDNSSIDEDY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCE
ALNLSANSKDIDVETGIYYATFSTFRGDLISLKLKDHLNLEKEPTEMVKVNMDRESLFYV
EEEECCCCCCCEEECCEEEEEEHHCCCCEEEEEECCCCCCCCCCCEEEEEECCCCEEEEE
TLDNLTRDLFSYDRVDDYTHDFKTNFEYNGKFYEYIKRYTFSNKGEYLIKLEIFLNNIDA
EHHHHHHHHHHHHCCCCCCHHCCCCCEECCHHHHHHHHHCCCCCCCEEEEEEEEEEECCC
NDNSDIDSYKFVLSSDIEKLSERGKLQYNNYLSQAVYFDTKLRYGKDGLSVISPKWVGSG
CCCCCCHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHEEECHHCCCCCCCCEECCCCCCCC
TKYFEVLVSKENMNVEFKQESKILKAFILNKVGNKNISDTFYIYAGPKDNGYLDLFNKED
CEEEEEEEECCCCCEEEHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCEEEECCCCC
LNSFGLSNVEFGMSVEKSLLYFIQVPMQLIMQIFYNVIPNWGLSIMFLTIVVRILIFPLT
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
FKSFRATAELSKLQPKMKEIQVKFKNDPKRLNEEMGKLYREEGVNPLGGCFPILLQLPVF
HHHHHHHHHHHHHCCCHHHEEEEECCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
FALYGLVNNFFLLRGASFIPGWIDDLSIGDSIYYFGYKVFMWTDIRILPFIMMVTQLIST
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEEEEEEECHHHHHHHHHHHHHHHH
IISSNVSFKSLGSQQKILYFGMPIMFFFILYDMPSGLLIYWITTNIFTILQQYYIKMNVS
HHHCCCCHHHCCCCCEEEEECHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHEECHH
ERRNR
HHCCH
>Mature Secondary Structure 
SQSKRILRAIYLSLFFIGIFMIIDDIFFSHKSPSVMDKEIGFNLDKDFDIDNSSIDEDY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCE
ALNLSANSKDIDVETGIYYATFSTFRGDLISLKLKDHLNLEKEPTEMVKVNMDRESLFYV
EEEECCCCCCCEEECCEEEEEEHHCCCCEEEEEECCCCCCCCCCCEEEEEECCCCEEEEE
TLDNLTRDLFSYDRVDDYTHDFKTNFEYNGKFYEYIKRYTFSNKGEYLIKLEIFLNNIDA
EHHHHHHHHHHHHCCCCCCHHCCCCCEECCHHHHHHHHHCCCCCCCEEEEEEEEEEECCC
NDNSDIDSYKFVLSSDIEKLSERGKLQYNNYLSQAVYFDTKLRYGKDGLSVISPKWVGSG
CCCCCCHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHEEECHHCCCCCCCCEECCCCCCCC
TKYFEVLVSKENMNVEFKQESKILKAFILNKVGNKNISDTFYIYAGPKDNGYLDLFNKED
CEEEEEEEECCCCCEEEHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCEEEECCCCC
LNSFGLSNVEFGMSVEKSLLYFIQVPMQLIMQIFYNVIPNWGLSIMFLTIVVRILIFPLT
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
FKSFRATAELSKLQPKMKEIQVKFKNDPKRLNEEMGKLYREEGVNPLGGCFPILLQLPVF
HHHHHHHHHHHHHCCCHHHEEEEECCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
FALYGLVNNFFLLRGASFIPGWIDDLSIGDSIYYFGYKVFMWTDIRILPFIMMVTQLIST
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEEEEEEECHHHHHHHHHHHHHHHH
IISSNVSFKSLGSQQKILYFGMPIMFFFILYDMPSGLLIYWITTNIFTILQQYYIKMNVS
HHHCCCCHHHCCCCCEEEEECHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHEECHH
ERRNR
HHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA