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The map label for this gene is dnaA [H]

Identifier: 187918302

GI number: 187918302

Start: 460217

End: 461671

Strand: Direct

Name: dnaA [H]

Synonym: BH0437

Alternate gene names: 187918302

Gene position: 460217-461671 (Clockwise)

Preceding gene: 187918298

Following gene: 187918303

Centisome position: 49.9

GC content: 28.25

Gene sequence:

>1455_bases
ATGCAAGAGGGAAAAAACATATGGAGCTTAATTTTAGCAGCAATAAGGAAAGAGCTTTCTGAAGAAGAATTTTACATATG
GTTTGAAAATTTATATTTCATAGATGCAACTGATGAGAATATAAAAATATCTGCTCCAAATTCTTTTCATAAAAATCAAG
TAGAAAAAAGATTTGCCAAAAGAATCAAAGAAATTCTCATTGAAAAAGGCCATAATACAATTAATGTTGAATTTATAAAT
TCACCAAATGACTCTAAGACTCATAACATGGAATCAAAAAATATCTCATTAAAAGACATTTCTACACAACAAGATTCACC
AGAAAAAAGAACGACCTTTAAAATTCACACTAAAAACATAATAGAGAGTACAAAACAATACACTACGAAAGAAGAAATTC
ACACGAAATATAGAAATCCTTTTCTTAAAAAGAAATACACATTTGAAAACTTCATTACAGGCCCAAATAATAAGCTTGCA
TATAATGCAAGCTTATCAATCGCAAAAAATCCAGGTAAAAAATATAATCCATGCCTAATTTATGGCGGAGTTGGTCTTGG
CAAAACACATTTACTTCAAAGTATAGGCAATAAAACAGAAGAATTACATAAAGAATTTAAAATACTTTATGTAACTGCTG
AAAATTTTTTAAATGAATTTGTAGAAAGCATAAAAACAAATGAAACAAAAAGATTTAAGAAGAAATACAGATATCTAGAT
ATGCTACTACTAGATGATATTCATGATTTACAGAAAAAAGAAGGTATACAAGAAGAGCTTTTTCACACTTTCAATGCTCT
TTATGAAGATAATAAACAAATGGTATTTACATGCGATAGACAACCCTCAGAACTCATAAATTTTACAGATAGACTTAAAA
GCAGATTTACAAGAGGATTAAATGTCGACATATCAAAACCAAACTTTGAACTAAGAGTAGCAATTATAGAAAAAAAAGCA
GAAGAAGATGGAATTAAAGTTCCAAAAAGCATTCTCAACTTAGTCGCTAAGAAAGTTACAACAAACATAAGAGATCTTGA
AGCTGCGGTAACCAAATTAAAAGCTCATATAGACCTTGAAGATATAGAAATTGACACTAGCACAGTAGACAAAATAATTA
AAGAGATAATAGTTTATGAGAACGATAACACAAATACGCATAACAAAATAAACATTGAAAGCATAAAAAAAGTTATCTTA
AGGGAATTAAAGCTTACAAATAAGGATATTGAAGGCAACAGCAAAAAACCTGAAATCACAAAAGCAAGACACATTTATGC
TTATCTTTTGAGGAATTTTACAGAGCTTTCAACAATTGAAATAGGTAAAATCATTGGGGGAAAAACCCATTCAACGGTGC
TTTATTCAATAAATAAGATAGATAAAGAGAGAAACAATGACCTAGAAATTAACAATTTAATCATAGAACTTATGAACAAA
ATAAACAAAAAATAA

Upstream 100 bases:

>100_bases
TAATGTTCCGGTTTATTATTATACTATATACTTATACATACATACACTAATAATCAAAAAAGATATAATGATAAAAAGCC
AAAATCAACGAGGATAATAT

Downstream 100 bases:

>100_bases
AAAATCTATAAAATTCAAAATACTTTTGAACAAATCAAACAAATAATTCATCAAAAAACACAAACAATTAGACATATACT
ATTACTTGTGGTATAAGGAG

Product: chromosomal replication initiator protein DnaA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 484; Mature: 484

Protein sequence:

>484_residues
MQEGKNIWSLILAAIRKELSEEEFYIWFENLYFIDATDENIKISAPNSFHKNQVEKRFAKRIKEILIEKGHNTINVEFIN
SPNDSKTHNMESKNISLKDISTQQDSPEKRTTFKIHTKNIIESTKQYTTKEEIHTKYRNPFLKKKYTFENFITGPNNKLA
YNASLSIAKNPGKKYNPCLIYGGVGLGKTHLLQSIGNKTEELHKEFKILYVTAENFLNEFVESIKTNETKRFKKKYRYLD
MLLLDDIHDLQKKEGIQEELFHTFNALYEDNKQMVFTCDRQPSELINFTDRLKSRFTRGLNVDISKPNFELRVAIIEKKA
EEDGIKVPKSILNLVAKKVTTNIRDLEAAVTKLKAHIDLEDIEIDTSTVDKIIKEIIVYENDNTNTHNKINIESIKKVIL
RELKLTNKDIEGNSKKPEITKARHIYAYLLRNFTELSTIEIGKIIGGKTHSTVLYSINKIDKERNNDLEINNLIIELMNK
INKK

Sequences:

>Translated_484_residues
MQEGKNIWSLILAAIRKELSEEEFYIWFENLYFIDATDENIKISAPNSFHKNQVEKRFAKRIKEILIEKGHNTINVEFIN
SPNDSKTHNMESKNISLKDISTQQDSPEKRTTFKIHTKNIIESTKQYTTKEEIHTKYRNPFLKKKYTFENFITGPNNKLA
YNASLSIAKNPGKKYNPCLIYGGVGLGKTHLLQSIGNKTEELHKEFKILYVTAENFLNEFVESIKTNETKRFKKKYRYLD
MLLLDDIHDLQKKEGIQEELFHTFNALYEDNKQMVFTCDRQPSELINFTDRLKSRFTRGLNVDISKPNFELRVAIIEKKA
EEDGIKVPKSILNLVAKKVTTNIRDLEAAVTKLKAHIDLEDIEIDTSTVDKIIKEIIVYENDNTNTHNKINIESIKKVIL
RELKLTNKDIEGNSKKPEITKARHIYAYLLRNFTELSTIEIGKIIGGKTHSTVLYSINKIDKERNNDLEINNLIIELMNK
INKK
>Mature_484_residues
MQEGKNIWSLILAAIRKELSEEEFYIWFENLYFIDATDENIKISAPNSFHKNQVEKRFAKRIKEILIEKGHNTINVEFIN
SPNDSKTHNMESKNISLKDISTQQDSPEKRTTFKIHTKNIIESTKQYTTKEEIHTKYRNPFLKKKYTFENFITGPNNKLA
YNASLSIAKNPGKKYNPCLIYGGVGLGKTHLLQSIGNKTEELHKEFKILYVTAENFLNEFVESIKTNETKRFKKKYRYLD
MLLLDDIHDLQKKEGIQEELFHTFNALYEDNKQMVFTCDRQPSELINFTDRLKSRFTRGLNVDISKPNFELRVAIIEKKA
EEDGIKVPKSILNLVAKKVTTNIRDLEAAVTKLKAHIDLEDIEIDTSTVDKIIKEIIVYENDNTNTHNKINIESIKKVIL
RELKLTNKDIEGNSKKPEITKARHIYAYLLRNFTELSTIEIGKIIGGKTHSTVLYSINKIDKERNNDLEINNLIIELMNK
INKK

Specific function: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box):5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phosph

COG id: COG0593

COG function: function code L; ATPase involved in DNA replication initiation

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dnaA family [H]

Homologues:

Organism=Escherichia coli, GI2367267, Length=481, Percent_Identity=31.1850311850312, Blast_Score=263, Evalue=2e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001957
- InterPro:   IPR020591
- InterPro:   IPR018312
- InterPro:   IPR013159
- InterPro:   IPR013317
- InterPro:   IPR010921 [H]

Pfam domain/function: PF00308 Bac_DnaA; PF08299 Bac_DnaA_C [H]

EC number: NA

Molecular weight: Translated: 56364; Mature: 56364

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: PS01008 DNAA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEGKNIWSLILAAIRKELSEEEFYIWFENLYFIDATDENIKISAPNSFHKNQVEKRFAK
CCCCHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEECCCCCEEEECCCCHHHHHHHHHHHH
RIKEILIEKGHNTINVEFINSPNDSKTHNMESKNISLKDISTQQDSPEKRTTFKIHTKNI
HHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCEEEEEHHHH
IESTKQYTTKEEIHTKYRNPFLKKKYTFENFITGPNNKLAYNASLSIAKNPGKKYNPCLI
HHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHCCCCCCCEEEECEEEEECCCCCCCCCEEE
YGGVGLGKTHLLQSIGNKTEELHKEFKILYVTAENFLNEFVESIKTNETKRFKKKYRYLD
ECCCCCCHHHHHHHHCCHHHHHHHHHEEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHH
MLLLDDIHDLQKKEGIQEELFHTFNALYEDNKQMVFTCDRQPSELINFTDRLKSRFTRGL
HHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCC
NVDISKPNFELRVAIIEKKAEEDGIKVPKSILNLVAKKVTTNIRDLEAAVTKLKAHIDLE
EEEECCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHH
DIEIDTSTVDKIIKEIIVYENDNTNTHNKINIESIKKVILRELKLTNKDIEGNSKKPEIT
HEECCHHHHHHHHHHHHEECCCCCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
KARHIYAYLLRNFTELSTIEIGKIIGGKTHSTVLYSINKIDKERNNDLEINNLIIELMNK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHCCCCCCCHHHHHHHHHHHH
INKK
HCCC
>Mature Secondary Structure
MQEGKNIWSLILAAIRKELSEEEFYIWFENLYFIDATDENIKISAPNSFHKNQVEKRFAK
CCCCHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEECCCCCEEEECCCCHHHHHHHHHHHH
RIKEILIEKGHNTINVEFINSPNDSKTHNMESKNISLKDISTQQDSPEKRTTFKIHTKNI
HHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCEEEEEHHHH
IESTKQYTTKEEIHTKYRNPFLKKKYTFENFITGPNNKLAYNASLSIAKNPGKKYNPCLI
HHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHCCCCCCCEEEECEEEEECCCCCCCCCEEE
YGGVGLGKTHLLQSIGNKTEELHKEFKILYVTAENFLNEFVESIKTNETKRFKKKYRYLD
ECCCCCCHHHHHHHHCCHHHHHHHHHEEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHH
MLLLDDIHDLQKKEGIQEELFHTFNALYEDNKQMVFTCDRQPSELINFTDRLKSRFTRGL
HHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCC
NVDISKPNFELRVAIIEKKAEEDGIKVPKSILNLVAKKVTTNIRDLEAAVTKLKAHIDLE
EEEECCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHH
DIEIDTSTVDKIIKEIIVYENDNTNTHNKINIESIKKVILRELKLTNKDIEGNSKKPEIT
HEECCHHHHHHHHHHHHEECCCCCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
KARHIYAYLLRNFTELSTIEIGKIIGGKTHSTVLYSINKIDKERNNDLEINNLIIELMNK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHCCCCCCCHHHHHHHHHHHH
INKK
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA