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The map label for this gene is 187918275

Identifier: 187918275

GI number: 187918275

Start: 424439

End: 425320

Strand: Direct

Name: 187918275

Synonym: BH0411

Alternate gene names: NA

Gene position: 424439-425320 (Clockwise)

Preceding gene: 187918274

Following gene: 187918276

Centisome position: 46.02

GC content: 28.12

Gene sequence:

>882_bases
ATGAAGAAAAAGCTAAAAATTTTATTATGTTTTTACATATTAATCTTATTAGGATTTCTATTCTTATATCAAAATCCCAA
AATCTTAAATAACATAAAAGAAATAGCTTCTAATTATTTAGAAAAACTCAAAGACAAAATTTACGGACCTGAAATTCCAA
CAGAACTAAAAGAAGAATATCTCTTACCAAAAGGATATCTTACTACCCAAGTGCTACATAAAAAATACTACTCTTTAGGA
TATGCTGAGAGTGCAAGACAATCAGAATGGGTAGCTTACCAATTAAAAAGAGAAATGGTTGAACTAGCTTTAACCTTGCT
TAGAGAAAAAAAAATAACGAGAAGTAAGAAATTTTTTGAAGATAAAGATATTAAAGGAATCTCTCCTAAGCTAAGCGACT
ATATAAGGAGCGGATATGACAGAGGGCACATCGTCAGTTCTGCTGACATGTCTTTTTCCAAAGATGCAATGCTAGATACT
TATTTCCTCTCAAACATATCTCCTCAACAAAGAGAATTCAATTCAGGAATCTGGCTTAAACTTGAACGCCTAGTTAGAAA
ATGGGCTATCTTAAAAGAAAAAATTTATATTGTTAGTGCAGGAATTTTAACAGAAAATAAAGGATTTATTGGAAAGAATA
AAATTCTAATCCCAAAAAATTTTTATAAAATAGTGCTATCATTAAACAATAACAATTCTTATGATATATTGGCTTTCATT
ATTCCAAATGAAAAGGCCCAAGACTTAGAACTTAGAAATTATGTTGTAAATGTTAATTTAATTGAAGATAAAACTAAAAT
AGATTTCTTTGCGAAACTTGATGCTGGAATAAAAAAAGTAATTAAAATGAAAAAAGACCTATATTCTTGGGAATTTAAAT
GA

Upstream 100 bases:

>100_bases
ACATCTATTCAAAAATTGAGTGTTTATTTATTGATACATTCAATATTTCTTTTGATTTTGGTATTAGATATAATCTTAAA
AGTAGCAAAGGGGCAAAATC

Downstream 100 bases:

>100_bases
AAACAATCTTTGCAAAATTAAACATTTTCCTCTTAATAACCTTTACCTTAGGCATTATTGTTATATCAATATTCATGTAT
CATATAAACTTTAATATAAA

Product: endonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MKKKLKILLCFYILILLGFLFLYQNPKILNNIKEIASNYLEKLKDKIYGPEIPTELKEEYLLPKGYLTTQVLHKKYYSLG
YAESARQSEWVAYQLKREMVELALTLLREKKITRSKKFFEDKDIKGISPKLSDYIRSGYDRGHIVSSADMSFSKDAMLDT
YFLSNISPQQREFNSGIWLKLERLVRKWAILKEKIYIVSAGILTENKGFIGKNKILIPKNFYKIVLSLNNNNSYDILAFI
IPNEKAQDLELRNYVVNVNLIEDKTKIDFFAKLDAGIKKVIKMKKDLYSWEFK

Sequences:

>Translated_293_residues
MKKKLKILLCFYILILLGFLFLYQNPKILNNIKEIASNYLEKLKDKIYGPEIPTELKEEYLLPKGYLTTQVLHKKYYSLG
YAESARQSEWVAYQLKREMVELALTLLREKKITRSKKFFEDKDIKGISPKLSDYIRSGYDRGHIVSSADMSFSKDAMLDT
YFLSNISPQQREFNSGIWLKLERLVRKWAILKEKIYIVSAGILTENKGFIGKNKILIPKNFYKIVLSLNNNNSYDILAFI
IPNEKAQDLELRNYVVNVNLIEDKTKIDFFAKLDAGIKKVIKMKKDLYSWEFK
>Mature_293_residues
MKKKLKILLCFYILILLGFLFLYQNPKILNNIKEIASNYLEKLKDKIYGPEIPTELKEEYLLPKGYLTTQVLHKKYYSLG
YAESARQSEWVAYQLKREMVELALTLLREKKITRSKKFFEDKDIKGISPKLSDYIRSGYDRGHIVSSADMSFSKDAMLDT
YFLSNISPQQREFNSGIWLKLERLVRKWAILKEKIYIVSAGILTENKGFIGKNKILIPKNFYKIVLSLNNNNSYDILAFI
IPNEKAQDLELRNYVVNVNLIEDKTKIDFFAKLDAGIKKVIKMKKDLYSWEFK

Specific function: Unknown

COG id: COG1864

COG function: function code F; DNA/RNA endonuclease G, NUC1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA/RNA non-specific endonuclease family [H]

Homologues:

Organism=Homo sapiens, GI53759134, Length=213, Percent_Identity=27.2300469483568, Blast_Score=95, Evalue=9e-20,
Organism=Homo sapiens, GI224451073, Length=230, Percent_Identity=27.3913043478261, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI224451075, Length=166, Percent_Identity=31.3253012048193, Blast_Score=88, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17505967, Length=223, Percent_Identity=27.8026905829596, Blast_Score=85, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6322253, Length=222, Percent_Identity=28.3783783783784, Blast_Score=88, Evalue=2e-18,
Organism=Drosophila melanogaster, GI20129899, Length=225, Percent_Identity=26.2222222222222, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24581065, Length=214, Percent_Identity=25.2336448598131, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI28571642, Length=209, Percent_Identity=23.9234449760766, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018524
- InterPro:   IPR001604
- InterPro:   IPR020821 [H]

Pfam domain/function: PF01223 Endonuclease_NS [H]

EC number: NA

Molecular weight: Translated: 34389; Mature: 34389

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: PS01070 NUCLEASE_NON_SPEC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKLKILLCFYILILLGFLFLYQNPKILNNIKEIASNYLEKLKDKIYGPEIPTELKEEY
CCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
LLPKGYLTTQVLHKKYYSLGYAESARQSEWVAYQLKREMVELALTLLREKKITRSKKFFE
CCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DKDIKGISPKLSDYIRSGYDRGHIVSSADMSFSKDAMLDTYFLSNISPQQREFNSGIWLK
CCCCCCCCHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHHHCCCHHHHHHCCCHHHH
LERLVRKWAILKEKIYIVSAGILTENKGFIGKNKILIPKNFYKIVLSLNNNNSYDILAFI
HHHHHHHHHHHHHHEEEEEECEEECCCCCCCCCEEEECCCEEEEEEEECCCCCEEEEEEE
IPNEKAQDLELRNYVVNVNLIEDKTKIDFFAKLDAGIKKVIKMKKDLYSWEFK
ECCCCCCCEEEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKKKLKILLCFYILILLGFLFLYQNPKILNNIKEIASNYLEKLKDKIYGPEIPTELKEEY
CCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
LLPKGYLTTQVLHKKYYSLGYAESARQSEWVAYQLKREMVELALTLLREKKITRSKKFFE
CCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DKDIKGISPKLSDYIRSGYDRGHIVSSADMSFSKDAMLDTYFLSNISPQQREFNSGIWLK
CCCCCCCCHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHHHCCCHHHHHHCCCHHHH
LERLVRKWAILKEKIYIVSAGILTENKGFIGKNKILIPKNFYKIVLSLNNNNSYDILAFI
HHHHHHHHHHHHHHEEEEEECEEECCCCCCCCCEEEECCCEEEEEEEECCCCCEEEEEEE
IPNEKAQDLELRNYVVNVNLIEDKTKIDFFAKLDAGIKKVIKMKKDLYSWEFK
ECCCCCCCEEEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9403685 [H]