Click here to switch to the map view.

The map label for this gene is glpD2 [H]

Identifier: 187918116

GI number: 187918116

Start: 250381

End: 251943

Strand: Direct

Name: glpD2 [H]

Synonym: BH0243

Alternate gene names: 187918116

Gene position: 250381-251943 (Clockwise)

Preceding gene: 187918115

Following gene: 187918120

Centisome position: 27.15

GC content: 31.41

Gene sequence:

>1563_bases
ATGAGTAAAAATGGAAAAGAAGAATTAAAAAACATTGATAATCAAGCTTTTGATTTAATCATAGTTGGCGGAGGAGCAAC
TGGTCTTAGTATTGGAATAGATTCAATTACAAGAGGATACAAAACTTTACTCATTGACAAATTTGACTATGCAAAAGGCA
CCTCCTCTAGATCAACTAAGTTAATACATGGAGGAGTAAGATATTTAGCCCAATTTAATTTATCTTTAGTAAAAGAGGCC
CTACATGAGAAAGCGTTATTTGAAAAAAATGCACCTCACCTAGTTAGTAAACGTGCATTTATTACCCCCATATACAACCT
CTTAAGCATACCCTACTACTATTTTGGACTAAGTTGGTACCATAACCTTCTTGGAAAGTACAAAAAGTCTAAATATAAAA
CAAAGCTACTATCAAAATCCAAAACAATAGAGAAAATGCCAAATATCAAAACCAAAGGCCTTAAATGTTCTGTTTTATAC
TATGACAATTCATTTGATGATGCTAGGATGGCGATAAGCATGCTTAGAACTTTTACTGAAAAAGGGGGGATTGCGTTTAA
TTATACGGAACTTACAGGTTTTACTAAAAGAAACGGCAAAATATCTGGTGCTATTATTAAAGATACTATTAATGGTGAAC
AAGTCATTATTAATAGTAAATGCATAATAAATGCAACAGGAATATTCGCAGACGAGCTCAGAAAATTAGATGATACTAAT
GCAACTAATATTATAAAACCTTCCCAAGGAACACATTTAATAATTAAAAAAGACAAACTACGTACCAAGTACGCAATGCT
TATGCCTACGACAAGCGATAAGAGAGTCTTATTTTCTATACCTTGGTATGATGGTATTATTTGCGGAAGTACAGATATTT
CAATAGATAAAATTGAGGAAGAACCCAAAAGACTAGAGAGCGAAATTGAATTCATAATAAAAAATATGAATAATTACTTA
GATATTAAAATAACAAAAAATGATATTCTAAGTGTTTACACAGGAATTAGACCCTTAATAATAGATCCCAAGAAAGAACA
AAATACCTCAAAAATATCAAGAAACGAGAAAATATTTGTATCAGACTCAAATCTCATTACAATTGCTGGAGGGAAATATA
CTACTTGCAGAAAGATGGCTGAAAAAGTTATACAAAAAGCAATAGACGCAAAATTAATACCTGATTCAATTCCCAAAACA
GAAAATTTAAAGCTGCACGGGTATATAGAAAGGGAAGAAGCACTTAAAATCCCTGAACACTTTAGAGTTTATGGGAGTGA
TTTTAAATATCTAAGTCAAATGAAAGACTTTAATAACAAGATTCACACCGATTTGCCATTAACTGAAGCTCAAATAACTT
TTGCCATTGAATTTGAACAAGCAAAAACTATTGAAGACATTTTATCAAGAAGAACAAGATCTCTACTTCTCAATGCAAAA
GCCACAATTGAAGCTACACCAAAGGTAGCTGAGATTATGATGCACAAACTTGGCAAATCTGAAAAATGGAAGAACGAACA
AATAAAAAGCTTTAAAGAAGTAGCAACAAAATATTTAGCTTAA

Upstream 100 bases:

>100_bases
AGCAAAAGTAGATGGTATATTTACAGACTTTACTGATACAGTAGTGAATTTCATCACAAAAATAAAACCATAGCCTTAAT
AAGGAGAATATTTAACTCTT

Downstream 100 bases:

>100_bases
TAAATGGGGGGTAATAAATCCTCCTTATTTTTATAGTATTAAGTGGATTAAATCTATTATTGCATAGAAAGATAAACACA
AACTTGGTCTCACCTAAGCA

Product: glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 520; Mature: 519

Protein sequence:

>520_residues
MSKNGKEELKNIDNQAFDLIIVGGGATGLSIGIDSITRGYKTLLIDKFDYAKGTSSRSTKLIHGGVRYLAQFNLSLVKEA
LHEKALFEKNAPHLVSKRAFITPIYNLLSIPYYYFGLSWYHNLLGKYKKSKYKTKLLSKSKTIEKMPNIKTKGLKCSVLY
YDNSFDDARMAISMLRTFTEKGGIAFNYTELTGFTKRNGKISGAIIKDTINGEQVIINSKCIINATGIFADELRKLDDTN
ATNIIKPSQGTHLIIKKDKLRTKYAMLMPTTSDKRVLFSIPWYDGIICGSTDISIDKIEEEPKRLESEIEFIIKNMNNYL
DIKITKNDILSVYTGIRPLIIDPKKEQNTSKISRNEKIFVSDSNLITIAGGKYTTCRKMAEKVIQKAIDAKLIPDSIPKT
ENLKLHGYIEREEALKIPEHFRVYGSDFKYLSQMKDFNNKIHTDLPLTEAQITFAIEFEQAKTIEDILSRRTRSLLLNAK
ATIEATPKVAEIMMHKLGKSEKWKNEQIKSFKEVATKYLA

Sequences:

>Translated_520_residues
MSKNGKEELKNIDNQAFDLIIVGGGATGLSIGIDSITRGYKTLLIDKFDYAKGTSSRSTKLIHGGVRYLAQFNLSLVKEA
LHEKALFEKNAPHLVSKRAFITPIYNLLSIPYYYFGLSWYHNLLGKYKKSKYKTKLLSKSKTIEKMPNIKTKGLKCSVLY
YDNSFDDARMAISMLRTFTEKGGIAFNYTELTGFTKRNGKISGAIIKDTINGEQVIINSKCIINATGIFADELRKLDDTN
ATNIIKPSQGTHLIIKKDKLRTKYAMLMPTTSDKRVLFSIPWYDGIICGSTDISIDKIEEEPKRLESEIEFIIKNMNNYL
DIKITKNDILSVYTGIRPLIIDPKKEQNTSKISRNEKIFVSDSNLITIAGGKYTTCRKMAEKVIQKAIDAKLIPDSIPKT
ENLKLHGYIEREEALKIPEHFRVYGSDFKYLSQMKDFNNKIHTDLPLTEAQITFAIEFEQAKTIEDILSRRTRSLLLNAK
ATIEATPKVAEIMMHKLGKSEKWKNEQIKSFKEVATKYLA
>Mature_519_residues
SKNGKEELKNIDNQAFDLIIVGGGATGLSIGIDSITRGYKTLLIDKFDYAKGTSSRSTKLIHGGVRYLAQFNLSLVKEAL
HEKALFEKNAPHLVSKRAFITPIYNLLSIPYYYFGLSWYHNLLGKYKKSKYKTKLLSKSKTIEKMPNIKTKGLKCSVLYY
DNSFDDARMAISMLRTFTEKGGIAFNYTELTGFTKRNGKISGAIIKDTINGEQVIINSKCIINATGIFADELRKLDDTNA
TNIIKPSQGTHLIIKKDKLRTKYAMLMPTTSDKRVLFSIPWYDGIICGSTDISIDKIEEEPKRLESEIEFIIKNMNNYLD
IKITKNDILSVYTGIRPLIIDPKKEQNTSKISRNEKIFVSDSNLITIAGGKYTTCRKMAEKVIQKAIDAKLIPDSIPKTE
NLKLHGYIEREEALKIPEHFRVYGSDFKYLSQMKDFNNKIHTDLPLTEAQITFAIEFEQAKTIEDILSRRTRSLLLNAKA
TIEATPKVAEIMMHKLGKSEKWKNEQIKSFKEVATKYLA

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=540, Percent_Identity=36.6666666666667, Blast_Score=344, Evalue=1e-94,
Organism=Homo sapiens, GI285002231, Length=540, Percent_Identity=36.6666666666667, Blast_Score=344, Evalue=1e-94,
Organism=Escherichia coli, GI2367226, Length=490, Percent_Identity=27.3469387755102, Blast_Score=152, Evalue=5e-38,
Organism=Escherichia coli, GI1788574, Length=484, Percent_Identity=25.2066115702479, Blast_Score=97, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI115534726, Length=532, Percent_Identity=34.9624060150376, Blast_Score=286, Evalue=2e-77,
Organism=Caenorhabditis elegans, GI17509253, Length=543, Percent_Identity=34.622467771639, Blast_Score=286, Evalue=2e-77,
Organism=Saccharomyces cerevisiae, GI6322036, Length=579, Percent_Identity=32.1243523316062, Blast_Score=281, Evalue=3e-76,
Organism=Drosophila melanogaster, GI161077125, Length=547, Percent_Identity=38.3912248628885, Blast_Score=332, Evalue=5e-91,
Organism=Drosophila melanogaster, GI24653942, Length=547, Percent_Identity=38.3912248628885, Blast_Score=332, Evalue=5e-91,
Organism=Drosophila melanogaster, GI24653944, Length=547, Percent_Identity=38.3912248628885, Blast_Score=332, Evalue=5e-91,
Organism=Drosophila melanogaster, GI20130025, Length=547, Percent_Identity=38.3912248628885, Blast_Score=332, Evalue=5e-91,
Organism=Drosophila melanogaster, GI19921278, Length=547, Percent_Identity=28.3363802559415, Blast_Score=220, Evalue=2e-57,
Organism=Drosophila melanogaster, GI24586295, Length=532, Percent_Identity=27.8195488721804, Blast_Score=214, Evalue=9e-56,
Organism=Drosophila melanogaster, GI45550977, Length=404, Percent_Identity=27.2277227722772, Blast_Score=160, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 59074; Mature: 58943

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKNGKEELKNIDNQAFDLIIVGGGATGLSIGIDSITRGYKTLLIDKFDYAKGTSSRSTK
CCCCCHHHHHCCCCCEEEEEEECCCCCCEEECHHHHHCCCCEEEEECCCCCCCCCCCCCH
LIHGGVRYLAQFNLSLVKEALHEKALFEKNAPHLVSKRAFITPIYNLLSIPYYYFGLSWY
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHCHHHHHHHHHH
HNLLGKYKKSKYKTKLLSKSKTIEKMPNIKTKGLKCSVLYYDNSFDDARMAISMLRTFTE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHH
KGGIAFNYTELTGFTKRNGKISGAIIKDTINGEQVIINSKCIINATGIFADELRKLDDTN
CCCEEEEEHHHCCEECCCCEEECEEEEECCCCCEEEEECEEEEEECCCCHHHHHHCCCCC
ATNIIKPSQGTHLIIKKDKLRTKYAMLMPTTSDKRVLFSIPWYDGIICGSTDISIDKIEE
CCCEECCCCCCEEEEECCCCCCEEEEEEECCCCCEEEEEECCCCCEEECCCCCCHHHHHH
EPKRLESEIEFIIKNMNNYLDIKITKNDILSVYTGIRPLIIDPKKEQNTSKISRNEKIFV
HHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHCCEEEEECCCCCCCHHHHCCCCEEEE
SDSNLITIAGGKYTTCRKMAEKVIQKAIDAKLIPDSIPKTENLKLHGYIEREEALKIPEH
ECCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEHHHHHCCCHH
FRVYGSDFKYLSQMKDFNNKIHTDLPLTEAQITFAIEFEQAKTIEDILSRRTRSLLLNAK
HEEECCCHHHHHHHHHHCCCCCCCCCCCEEEEEEEEEECHHHHHHHHHHHHHHHHEEECC
ATIEATPKVAEIMMHKLGKSEKWKNEQIKSFKEVATKYLA
EEEECCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SKNGKEELKNIDNQAFDLIIVGGGATGLSIGIDSITRGYKTLLIDKFDYAKGTSSRSTK
CCCCHHHHHCCCCCEEEEEEECCCCCCEEECHHHHHCCCCEEEEECCCCCCCCCCCCCH
LIHGGVRYLAQFNLSLVKEALHEKALFEKNAPHLVSKRAFITPIYNLLSIPYYYFGLSWY
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHCHHHHHHHHHH
HNLLGKYKKSKYKTKLLSKSKTIEKMPNIKTKGLKCSVLYYDNSFDDARMAISMLRTFTE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHH
KGGIAFNYTELTGFTKRNGKISGAIIKDTINGEQVIINSKCIINATGIFADELRKLDDTN
CCCEEEEEHHHCCEECCCCEEECEEEEECCCCCEEEEECEEEEEECCCCHHHHHHCCCCC
ATNIIKPSQGTHLIIKKDKLRTKYAMLMPTTSDKRVLFSIPWYDGIICGSTDISIDKIEE
CCCEECCCCCCEEEEECCCCCCEEEEEEECCCCCEEEEEECCCCCEEECCCCCCHHHHHH
EPKRLESEIEFIIKNMNNYLDIKITKNDILSVYTGIRPLIIDPKKEQNTSKISRNEKIFV
HHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHCCEEEEECCCCCCCHHHHCCCCEEEE
SDSNLITIAGGKYTTCRKMAEKVIQKAIDAKLIPDSIPKTENLKLHGYIEREEALKIPEH
ECCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEHHHHHCCCHH
FRVYGSDFKYLSQMKDFNNKIHTDLPLTEAQITFAIEFEQAKTIEDILSRRTRSLLLNAK
HEEECCCHHHHHHHHHHCCCCCCCCCCCEEEEEEEEEECHHHHHHHHHHHHHHHHEEECC
ATIEATPKVAEIMMHKLGKSEKWKNEQIKSFKEVATKYLA
EEEECCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]