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The map label for this gene is katE [H]

Identifier: 187736548

GI number: 187736548

Start: 2515550

End: 2517805

Strand: Direct

Name: katE [H]

Synonym: Amuc_2070

Alternate gene names: 187736548

Gene position: 2515550-2517805 (Clockwise)

Preceding gene: 187736547

Following gene: 187736551

Centisome position: 94.42

GC content: 55.05

Gene sequence:

>2256_bases
ATGAAAAAAAAGAAACCGCCCATGGAAGACAGCGCCGCCCCTTTTCCCAATGGAAAAGAAGCTGCTCCCCATTATACGGA
TACAATTGATCCGGAATTGATCAAACCCACTCCAAAACCTACGCCGCCCAATGCGGAACCTTCCGCGCCCGGTTCCATGA
AGATGCCGGATAACGCTACGGAAAAAATCAGGGAGCTGGATGCCATGCGCTCCAACGGCATGGGACAGGCCCTCACAAGC
AACCTGGGAGTTAAAATATCCGATGATCAAAACACACTTAAAGCAGGAAGCAGAGGCCCCTCTCTGCTTGAAGACTTCCA
CTTTCTGGAGAAAATGGCTCATTTTGACCAGGAGCGGATACCGGAACGCGTGGTTCACGCAAGAGGTTCCGGGGCACATG
GTTATTTTCAGGTGTACAAATCCCTTTCCAAGTACACCAAAGCGGCTTTTTTGCAGGATCCGGGAGAAAAAACCCCGGTC
TTTGTGCGTTTTTCCACCGTGCAGGGCTTCAGAGGATCTCCGGATACAGTAAGGGATATCCGCGGTTGGGCTACCAAATT
CTATACCAAGGAAGGCAACTATGATCTGGTAGGCAATAACACGCCCGTCTTCTTCATTCAGGATGCCATCAAATTTCCGG
ATTTCGTTCATGCCGTCAAACCGGAACCCCACAATGAAATGCCCCAGGGGCAGACGGCCCATGACTCTTTCTGGGACTAC
GTCTCCCTGCAGCCGGAAACTCTGCATAACGTCATGTGGGCCATGTCGGACCGCGGCATCCCCAGAAGCTTCCGTACGAT
GGAAGGGTTCGGCATCCATACGTACAAACTGGTCAATGAAGAAGGAAAAAGCACTTTCGTCCGTTTCCACTGGAAACCGG
TGTACGGGAAAAAATCCCTGGTGTGGGATGAAGCCCAGGTATTGACAGGACGCGATCCTGACTTCCACCGCAAGGATCTC
TGGCAATCCATTGAAGCCGGAGATTATCCGGAATACGAGCTGGGTCTGCAGCTCATCCCGGAAGAAGACGCAGACCAGCT
CGACTTCGATATTCTGGACGCTACCAAGCTCATTCCGGAAGCTCTGGTTCCCGTGGAAATCGTCGGGAAAATGGTGCTGA
ACCGCAACCCGGACAACTTTTTTGCGGAAACGGAACAGGTAGCCTTCTGCCCCGCCAATATCGTGCCGGGCATTGATTTT
TCAGACGATCCGCTGCTCCAGGGCCGTATTTTCTCTTACAGCGATACCCAGCGGCACCGGCTGGGAGGAGCCAATTTCAC
GGAAATTCCCATCAACCGCCCCATTTGCCCCTTCCACAACAACCAGAGGGACGGCTTCCACCGTATGCAGATAGACGCCT
CTCCGGCCAACTATGATCCCAATTCCATCGGGAACAACTGGCCGAGAGAAACGCCCCCGGAGAAAGGCGGCTTCACCACC
AGCCCCCAGACGGTAAGCGGTGTCAAGGAACGTCTGCGGAACCCCTCCTTCGCGGAATACTATTCCCACCCCCGGTTGTT
CTGGATGAGTCAAACTCCGGTGGAACAGGAGCACATTATCAACGCGTTCAGCTTTGAGCTGGGCAAGGTGACGCGCCCCT
ATATTCGGGAACGCGTGGTGGACCTTCTGACACGCATTGATCCGGACCTGGCAAGCGGAGTGGCCCGCAACCTGGGAATT
CAACTCACCAGGGAACAGCTCAGCAGGGAACTTCCCAGGCCCGTCTGCGGCCTGGAACAAGATCCGTCATTGAGCCTGTA
TGCCCATACGGACGGCAACCTCAAAGGCCTCCGCGTCTCTTTACTGGCAGCGGACGGCGTCAGCCTGAAATCCGTGAAAG
AAATCTGCGAGGCCCTGCATGAAGAAGGCATCCACCCCCAAATCATTGCCCCGCACATGGGAAGCGTAACAACGGAAGAA
GGGGAAGATCTGCCTGTTAACGGGACTCTGTCCGGCACTCCTTCCGTCCTGTTTGACTCCGTCATCGTCCCGGAAGGAGA
ACAAAGCATCGCAGCGCTCCTGAAAGACGGAGATGCCAAGTACCATTTGCGCCAGGCCTACAGGCACCTGAAAGCCATCG
GACTGCCCGGCAACGCCAAAGCCATGCTTGAGGCAGCCTCCCTGCCCCAGGATATGGATGATGCCGGACTGCTCATGCCG
AAGGACACCAAATCCCTGATGCCCTCCTTCATCACGGCCATGAAACAGCACCGCGTCTGGAGCCGCGAGCCTAAAACCCT
TGATTTCGGCGCCTAG

Upstream 100 bases:

>100_bases
CGGAGAAATACTGATGACAAAACAGGACGGAACATCCCCGGAAAAAGGGAAGTCGAACTATTACCCACATAGAAAAATCC
GGTCCCTCATGAACAAGCCA

Downstream 100 bases:

>100_bases
ATTCGTTCCTTATTCAGGAACCGCTTCCCAATACAGGCTGCCCCGTCGAAAGGCGCGGCAGCCGTTTTTATTAAAAAATC
CGAGGAGTTATAGCATCATA

Product: hydroperoxidase II

Products: NA

Alternate protein names: Hydroxyperoxidase II [H]

Number of amino acids: Translated: 751; Mature: 751

Protein sequence:

>751_residues
MKKKKPPMEDSAAPFPNGKEAAPHYTDTIDPELIKPTPKPTPPNAEPSAPGSMKMPDNATEKIRELDAMRSNGMGQALTS
NLGVKISDDQNTLKAGSRGPSLLEDFHFLEKMAHFDQERIPERVVHARGSGAHGYFQVYKSLSKYTKAAFLQDPGEKTPV
FVRFSTVQGFRGSPDTVRDIRGWATKFYTKEGNYDLVGNNTPVFFIQDAIKFPDFVHAVKPEPHNEMPQGQTAHDSFWDY
VSLQPETLHNVMWAMSDRGIPRSFRTMEGFGIHTYKLVNEEGKSTFVRFHWKPVYGKKSLVWDEAQVLTGRDPDFHRKDL
WQSIEAGDYPEYELGLQLIPEEDADQLDFDILDATKLIPEALVPVEIVGKMVLNRNPDNFFAETEQVAFCPANIVPGIDF
SDDPLLQGRIFSYSDTQRHRLGGANFTEIPINRPICPFHNNQRDGFHRMQIDASPANYDPNSIGNNWPRETPPEKGGFTT
SPQTVSGVKERLRNPSFAEYYSHPRLFWMSQTPVEQEHIINAFSFELGKVTRPYIRERVVDLLTRIDPDLASGVARNLGI
QLTREQLSRELPRPVCGLEQDPSLSLYAHTDGNLKGLRVSLLAADGVSLKSVKEICEALHEEGIHPQIIAPHMGSVTTEE
GEDLPVNGTLSGTPSVLFDSVIVPEGEQSIAALLKDGDAKYHLRQAYRHLKAIGLPGNAKAMLEAASLPQDMDDAGLLMP
KDTKSLMPSFITAMKQHRVWSREPKTLDFGA

Sequences:

>Translated_751_residues
MKKKKPPMEDSAAPFPNGKEAAPHYTDTIDPELIKPTPKPTPPNAEPSAPGSMKMPDNATEKIRELDAMRSNGMGQALTS
NLGVKISDDQNTLKAGSRGPSLLEDFHFLEKMAHFDQERIPERVVHARGSGAHGYFQVYKSLSKYTKAAFLQDPGEKTPV
FVRFSTVQGFRGSPDTVRDIRGWATKFYTKEGNYDLVGNNTPVFFIQDAIKFPDFVHAVKPEPHNEMPQGQTAHDSFWDY
VSLQPETLHNVMWAMSDRGIPRSFRTMEGFGIHTYKLVNEEGKSTFVRFHWKPVYGKKSLVWDEAQVLTGRDPDFHRKDL
WQSIEAGDYPEYELGLQLIPEEDADQLDFDILDATKLIPEALVPVEIVGKMVLNRNPDNFFAETEQVAFCPANIVPGIDF
SDDPLLQGRIFSYSDTQRHRLGGANFTEIPINRPICPFHNNQRDGFHRMQIDASPANYDPNSIGNNWPRETPPEKGGFTT
SPQTVSGVKERLRNPSFAEYYSHPRLFWMSQTPVEQEHIINAFSFELGKVTRPYIRERVVDLLTRIDPDLASGVARNLGI
QLTREQLSRELPRPVCGLEQDPSLSLYAHTDGNLKGLRVSLLAADGVSLKSVKEICEALHEEGIHPQIIAPHMGSVTTEE
GEDLPVNGTLSGTPSVLFDSVIVPEGEQSIAALLKDGDAKYHLRQAYRHLKAIGLPGNAKAMLEAASLPQDMDDAGLLMP
KDTKSLMPSFITAMKQHRVWSREPKTLDFGA
>Mature_751_residues
MKKKKPPMEDSAAPFPNGKEAAPHYTDTIDPELIKPTPKPTPPNAEPSAPGSMKMPDNATEKIRELDAMRSNGMGQALTS
NLGVKISDDQNTLKAGSRGPSLLEDFHFLEKMAHFDQERIPERVVHARGSGAHGYFQVYKSLSKYTKAAFLQDPGEKTPV
FVRFSTVQGFRGSPDTVRDIRGWATKFYTKEGNYDLVGNNTPVFFIQDAIKFPDFVHAVKPEPHNEMPQGQTAHDSFWDY
VSLQPETLHNVMWAMSDRGIPRSFRTMEGFGIHTYKLVNEEGKSTFVRFHWKPVYGKKSLVWDEAQVLTGRDPDFHRKDL
WQSIEAGDYPEYELGLQLIPEEDADQLDFDILDATKLIPEALVPVEIVGKMVLNRNPDNFFAETEQVAFCPANIVPGIDF
SDDPLLQGRIFSYSDTQRHRLGGANFTEIPINRPICPFHNNQRDGFHRMQIDASPANYDPNSIGNNWPRETPPEKGGFTT
SPQTVSGVKERLRNPSFAEYYSHPRLFWMSQTPVEQEHIINAFSFELGKVTRPYIRERVVDLLTRIDPDLASGVARNLGI
QLTREQLSRELPRPVCGLEQDPSLSLYAHTDGNLKGLRVSLLAADGVSLKSVKEICEALHEEGIHPQIIAPHMGSVTTEE
GEDLPVNGTLSGTPSVLFDSVIVPEGEQSIAALLKDGDAKYHLRQAYRHLKAIGLPGNAKAMLEAASLPQDMDDAGLLMP
KDTKSLMPSFITAMKQHRVWSREPKTLDFGA

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family. HPII subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=503, Percent_Identity=42.1471172962227, Blast_Score=382, Evalue=1e-106,
Organism=Escherichia coli, GI48994891, Length=737, Percent_Identity=63.3649932157395, Blast_Score=957, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71998444, Length=484, Percent_Identity=45.2479338842975, Blast_Score=407, Evalue=1e-114,
Organism=Caenorhabditis elegans, GI25147792, Length=488, Percent_Identity=44.0573770491803, Blast_Score=405, Evalue=1e-113,
Organism=Caenorhabditis elegans, GI25151141, Length=500, Percent_Identity=43.6, Blast_Score=404, Evalue=1e-112,
Organism=Saccharomyces cerevisiae, GI6320462, Length=495, Percent_Identity=36.7676767676768, Blast_Score=321, Evalue=3e-88,
Organism=Saccharomyces cerevisiae, GI6321525, Length=508, Percent_Identity=36.8110236220472, Blast_Score=318, Evalue=1e-87,
Organism=Drosophila melanogaster, GI17981717, Length=491, Percent_Identity=40.122199592668, Blast_Score=360, Evalue=2e-99,
Organism=Drosophila melanogaster, GI19920968, Length=480, Percent_Identity=39.7916666666667, Blast_Score=359, Evalue=3e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 84036; Mature: 84036

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: PS00437 CATALASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKKPPMEDSAAPFPNGKEAAPHYTDTIDPELIKPTPKPTPPNAEPSAPGSMKMPDNAT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCHH
EKIRELDAMRSNGMGQALTSNLGVKISDDQNTLKAGSRGPSLLEDFHFLEKMAHFDQERI
HHHHHHHHHHCCCCCHHHHCCCCEEECCCCHHHHCCCCCHHHHHHHHHHHHHHHCCHHHH
PERVVHARGSGAHGYFQVYKSLSKYTKAAFLQDPGEKTPVFVRFSTVQGFRGSPDTVRDI
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCHHHHHH
RGWATKFYTKEGNYDLVGNNTPVFFIQDAIKFPDFVHAVKPEPHNEMPQGQTAHDSFWDY
HHHHHHEEECCCCEEEECCCCCEEEEECHHCCCHHHHHCCCCCCCCCCCCCCCCHHHHCE
VSLQPETLHNVMWAMSDRGIPRSFRTMEGFGIHTYKLVNEEGKSTFVRFHWKPVYGKKSL
EECCHHHHHHHHHHHHCCCCCCHHHHHCCCCCEEEEEECCCCCEEEEEEEEEECCCCCCE
VWDEAQVLTGRDPDFHRKDLWQSIEAGDYPEYELGLQLIPEEDADQLDFDILDATKLIPE
EECCHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHH
ALVPVEIVGKMVLNRNPDNFFAETEQVAFCPANIVPGIDFSDDPLLQGRIFSYSDTQRHR
HCCCHHHHHHHHHCCCCCHHHHCCCCEEECCCCCCCCCCCCCCCCCCCEEECCCCCHHHH
LGGANFTEIPINRPICPFHNNQRDGFHRMQIDASPANYDPNSIGNNWPRETPPEKGGFTT
CCCCCCEECCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
SPQTVSGVKERLRNPSFAEYYSHPRLFWMSQTPVEQEHIINAFSFELGKVTRPYIRERVV
CCHHHHHHHHHHCCCCHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHH
DLLTRIDPDLASGVARNLGIQLTREQLSRELPRPVCGLEQDPSLSLYAHTDGNLKGLRVS
HHHHHCCHHHHHHHHHHCCCEEHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCEEEE
LLAADGVSLKSVKEICEALHEEGIHPQIIAPHMGSVTTEEGEDLPVNGTLSGTPSVLFDS
EEEECCCCHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHC
VIVPEGEQSIAALLKDGDAKYHLRQAYRHLKAIGLPGNAKAMLEAASLPQDMDDAGLLMP
EECCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCC
KDTKSLMPSFITAMKQHRVWSREPKTLDFGA
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MKKKKPPMEDSAAPFPNGKEAAPHYTDTIDPELIKPTPKPTPPNAEPSAPGSMKMPDNAT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCHH
EKIRELDAMRSNGMGQALTSNLGVKISDDQNTLKAGSRGPSLLEDFHFLEKMAHFDQERI
HHHHHHHHHHCCCCCHHHHCCCCEEECCCCHHHHCCCCCHHHHHHHHHHHHHHHCCHHHH
PERVVHARGSGAHGYFQVYKSLSKYTKAAFLQDPGEKTPVFVRFSTVQGFRGSPDTVRDI
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCHHHHHH
RGWATKFYTKEGNYDLVGNNTPVFFIQDAIKFPDFVHAVKPEPHNEMPQGQTAHDSFWDY
HHHHHHEEECCCCEEEECCCCCEEEEECHHCCCHHHHHCCCCCCCCCCCCCCCCHHHHCE
VSLQPETLHNVMWAMSDRGIPRSFRTMEGFGIHTYKLVNEEGKSTFVRFHWKPVYGKKSL
EECCHHHHHHHHHHHHCCCCCCHHHHHCCCCCEEEEEECCCCCEEEEEEEEEECCCCCCE
VWDEAQVLTGRDPDFHRKDLWQSIEAGDYPEYELGLQLIPEEDADQLDFDILDATKLIPE
EECCHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHH
ALVPVEIVGKMVLNRNPDNFFAETEQVAFCPANIVPGIDFSDDPLLQGRIFSYSDTQRHR
HCCCHHHHHHHHHCCCCCHHHHCCCCEEECCCCCCCCCCCCCCCCCCCEEECCCCCHHHH
LGGANFTEIPINRPICPFHNNQRDGFHRMQIDASPANYDPNSIGNNWPRETPPEKGGFTT
CCCCCCEECCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
SPQTVSGVKERLRNPSFAEYYSHPRLFWMSQTPVEQEHIINAFSFELGKVTRPYIRERVV
CCHHHHHHHHHHCCCCHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHH
DLLTRIDPDLASGVARNLGIQLTREQLSRELPRPVCGLEQDPSLSLYAHTDGNLKGLRVS
HHHHHCCHHHHHHHHHHCCCEEHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCEEEE
LLAADGVSLKSVKEICEALHEEGIHPQIIAPHMGSVTTEEGEDLPVNGTLSGTPSVLFDS
EEEECCCCHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHC
VIVPEGEQSIAALLKDGDAKYHLRQAYRHLKAIGLPGNAKAMLEAASLPQDMDDAGLLMP
EECCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCC
KDTKSLMPSFITAMKQHRVWSREPKTLDFGA
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1987146; 9097039; 9278503; 9144772; 7663946; 10091651; 11455600 [H]