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The map label for this gene is glaA

Identifier: 187735954

GI number: 187735954

Start: 1753731

End: 1755521

Strand: Reverse

Name: glaA

Synonym: Amuc_1463

Alternate gene names: 187735954

Gene position: 1755521-1753731 (Counterclockwise)

Preceding gene: 187735955

Following gene: 187735947

Centisome position: 65.9

GC content: 55.11

Gene sequence:

>1791_bases
ATGCAAAACCCCGTGGCCTCCCTGCTTTTTATTCTCGCAATGTTGACAGGGCCATGCCCGGCAGCGGATTATCCGGAACG
GACGGAGCGCACGCAATCCGCAGGGAACCATGTCTGGCATATAGACCCGGACAAGGGAAATGACGGCAATCCGGGAACGG
CCCCATCCACGGCGTGGAAAAGCATGGCGCCGGCCAACCGTCTCATCATGGCGCGGGGAGATACGCTCGTCATCCATCCG
GGGGAACATGCCGTCTCCCTGGCGCTGATGGGGGAAGGTTCCAAACAGGCCCCGGTCACCATCCGGTTCATGCCCGGCAG
GCATATCTTCAAACACGGTGCCCTGATGACCGGAAAACCGCAGATTTCCAACACCAACGATGCGCCCAACGAGCCCAAGG
CCATGGCTATCCGCCTGATGGAAGCCAAAAACATACGCCTGGAGGGAAAGCCGGGAGCCACCGACATCCTGCTGGAAGGA
AAAGCCATCTTTGTCTGCATGGAACATGCGGAAAACGTTTCCCTGAACGGCCTGGGTTTTGATTACCTGCATCCGACCAT
GGGAGAATTTCTGGTCACGGAAGTTGAAGGGGATACCATGAAAGCAACTATTCCGGACGGAACCCTGTACACAGTGAAGG
ATGGAAACCTGACCTGGCACGGACCCGGCTGGGAATTCCGCATGGGAGGGTATTCCAAAGTTTTCGATTCCGCCTCCGGC
ACTTTCCAGGGCCGTTTCGACCCCGGGAAAACAGTCATCAGAGAATTGTCTCCCGGAAAAATCAGCATTACGTTCAAGGA
AGGCTCACCAACCATGAAACCGGGCCAATCCTACCAGAACCGCAATACCCGGAGGGACTGCTGCGGCTTCTTTCAATACA
GAAGCAAAAACATCCTCTGGAATAACTGCCATATTTACTATATGCACGGCATGGGCGTCGTTTCCCAGTTCTGCGAGAAC
ATCATGTTCAGCCACTTGAAAATAGCCCCGCGCCCCCGTTCCCTCCGCACCAATTCCTCCTGGGCGGATAATCTGCACTT
TTCCGGATGCCGGGGAAAAATCATCGTCAAAGATTGCGTGCTGGGAGCCTCCCATGATGACGCCGTTAATGTTCATGGAA
CCCACTTGCGCATTATAGACAGGCCGGCCCCCAACAAAATCACCGTCCGGTTCATGCATCCCCAGACCTTCGGCTTTGAC
GCCTTTGCCGCAGGAGACCGGATCGATTATGTTTCCTGCAACACGCTGGTACCTTATGCATCCAATACCGTTTCCGGCGT
CAAACAACTCAATGAAAAGGAAATAGAACTTACATTGCAACATCCCAATCCCGGGAACATCCAGCCTGACGATGTTGTGG
AAAACGTCACATGGACGCCGTCCGTCCACATCAGCAATACGGTATGCCGCCACATTCCCACCAGGGGCTTCCTGCTCACC
ACTAGGAAGCCGGTGCTGGTTGAACGGTGCCGGTTTGAAAAAACGGGCATGCCCGCCATCCTGGTGGAAGATGACGCCTC
CGGCTGGTATGAATCCGGCGTGGTCAGGAACATGACCATTTCCCGCAATACCTTTATCCAATGCGGAGAAGCCGTCATCC
AGATCGTGCCGCACGCTCCACGGCCGGAAGGGGACGTTCACCGGAACATCACCATTACCGGAAACACGTTTGACCTCAAA
AACGGAACCGCCATCCGCATTCGCCATACCGGTGACGTCAAGGCGGAGAAAAACACTTTCACCAAAGACGGGAAGAAAAT
CCCTGAGGAAAAGGCGGTGGATATCCGGTAG

Upstream 100 bases:

>100_bases
GGGGCCTCCCAGGTGAGCCATGGAAAAGCTGCGGCTTTTTCTCCCGGCCCTGCAAGAATTATCCTTGTCCCGAAAACCGT
GTTCCTGTAGGAGTTGCAGC

Downstream 100 bases:

>100_bases
AAAACCTCTTTCTTACCGGTGCCGGGAAACATGCACCGTTACGGAAACGCTGTCCGTCCGCGGCAGAATAAACTTGCGCA
GGGTAACAACCACGTGCCGC

Product: hypothetical protein

Products: NA

Alternate protein names: Exo-alpha-galactosidase A

Number of amino acids: Translated: 596; Mature: 596

Protein sequence:

>596_residues
MQNPVASLLFILAMLTGPCPAADYPERTERTQSAGNHVWHIDPDKGNDGNPGTAPSTAWKSMAPANRLIMARGDTLVIHP
GEHAVSLALMGEGSKQAPVTIRFMPGRHIFKHGALMTGKPQISNTNDAPNEPKAMAIRLMEAKNIRLEGKPGATDILLEG
KAIFVCMEHAENVSLNGLGFDYLHPTMGEFLVTEVEGDTMKATIPDGTLYTVKDGNLTWHGPGWEFRMGGYSKVFDSASG
TFQGRFDPGKTVIRELSPGKISITFKEGSPTMKPGQSYQNRNTRRDCCGFFQYRSKNILWNNCHIYYMHGMGVVSQFCEN
IMFSHLKIAPRPRSLRTNSSWADNLHFSGCRGKIIVKDCVLGASHDDAVNVHGTHLRIIDRPAPNKITVRFMHPQTFGFD
AFAAGDRIDYVSCNTLVPYASNTVSGVKQLNEKEIELTLQHPNPGNIQPDDVVENVTWTPSVHISNTVCRHIPTRGFLLT
TRKPVLVERCRFEKTGMPAILVEDDASGWYESGVVRNMTISRNTFIQCGEAVIQIVPHAPRPEGDVHRNITITGNTFDLK
NGTAIRIRHTGDVKAEKNTFTKDGKKIPEEKAVDIR

Sequences:

>Translated_596_residues
MQNPVASLLFILAMLTGPCPAADYPERTERTQSAGNHVWHIDPDKGNDGNPGTAPSTAWKSMAPANRLIMARGDTLVIHP
GEHAVSLALMGEGSKQAPVTIRFMPGRHIFKHGALMTGKPQISNTNDAPNEPKAMAIRLMEAKNIRLEGKPGATDILLEG
KAIFVCMEHAENVSLNGLGFDYLHPTMGEFLVTEVEGDTMKATIPDGTLYTVKDGNLTWHGPGWEFRMGGYSKVFDSASG
TFQGRFDPGKTVIRELSPGKISITFKEGSPTMKPGQSYQNRNTRRDCCGFFQYRSKNILWNNCHIYYMHGMGVVSQFCEN
IMFSHLKIAPRPRSLRTNSSWADNLHFSGCRGKIIVKDCVLGASHDDAVNVHGTHLRIIDRPAPNKITVRFMHPQTFGFD
AFAAGDRIDYVSCNTLVPYASNTVSGVKQLNEKEIELTLQHPNPGNIQPDDVVENVTWTPSVHISNTVCRHIPTRGFLLT
TRKPVLVERCRFEKTGMPAILVEDDASGWYESGVVRNMTISRNTFIQCGEAVIQIVPHAPRPEGDVHRNITITGNTFDLK
NGTAIRIRHTGDVKAEKNTFTKDGKKIPEEKAVDIR
>Mature_596_residues
MQNPVASLLFILAMLTGPCPAADYPERTERTQSAGNHVWHIDPDKGNDGNPGTAPSTAWKSMAPANRLIMARGDTLVIHP
GEHAVSLALMGEGSKQAPVTIRFMPGRHIFKHGALMTGKPQISNTNDAPNEPKAMAIRLMEAKNIRLEGKPGATDILLEG
KAIFVCMEHAENVSLNGLGFDYLHPTMGEFLVTEVEGDTMKATIPDGTLYTVKDGNLTWHGPGWEFRMGGYSKVFDSASG
TFQGRFDPGKTVIRELSPGKISITFKEGSPTMKPGQSYQNRNTRRDCCGFFQYRSKNILWNNCHIYYMHGMGVVSQFCEN
IMFSHLKIAPRPRSLRTNSSWADNLHFSGCRGKIIVKDCVLGASHDDAVNVHGTHLRIIDRPAPNKITVRFMHPQTFGFD
AFAAGDRIDYVSCNTLVPYASNTVSGVKQLNEKEIELTLQHPNPGNIQPDDVVENVTWTPSVHISNTVCRHIPTRGFLLT
TRKPVLVERCRFEKTGMPAILVEDDASGWYESGVVRNMTISRNTFIQCGEAVIQIVPHAPRPEGDVHRNITITGNTFDLK
NGTAIRIRHTGDVKAEKNTFTKDGKKIPEEKAVDIR

Specific function: Alpha-galactosidase that specifically removes branched alpha-1,3-linked galactose residues present in blood group B antigens. Has no activity toward linear alpha-1,3-linked galactose residues

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 4 PbH1 repeats

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLAA_AKKM8 (B2UL12)

Other databases:

- EMBL:   CP001071
- RefSeq:   YP_001878066.1
- GeneID:   6275708
- GenomeReviews:   CP001071_GR
- KEGG:   amu:Amuc_1463
- OMA:   LKLRFMH
- ProtClustDB:   CLSK823424
- InterPro:   IPR006626
- InterPro:   IPR012334
- InterPro:   IPR011050
- Gene3D:   G3DSA:2.160.20.10
- SMART:   SM00710

Pfam domain/function: SSF51126 Pectin_lyas_like

EC number: =3.2.1.22

Molecular weight: Translated: 65953; Mature: 65953

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNPVASLLFILAMLTGPCPAADYPERTERTQSAGNHVWHIDPDKGNDGNPGTAPSTAWK
CCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCHHHH
SMAPANRLIMARGDTLVIHPGEHAVSLALMGEGSKQAPVTIRFMPGRHIFKHGALMTGKP
HCCCCCEEEEEECCEEEEECCCCEEEEEEECCCCCCCCEEEEECCCCHHHHCCCEEECCC
QISNTNDAPNEPKAMAIRLMEAKNIRLEGKPGATDILLEGKAIFVCMEHAENVSLNGLGF
CCCCCCCCCCCCCEEEEEEEECCCEEEECCCCCEEEEECCCEEEEEEECCCCCEECCCCC
DYLHPTMGEFLVTEVEGDTMKATIPDGTLYTVKDGNLTWHGPGWEFRMGGYSKVFDSASG
HHHCCCCCCEEEEEECCCEEEEECCCCEEEEEECCCEEECCCCEEEECCCHHHHHCCCCC
TFQGRFDPGKTVIRELSPGKISITFKEGSPTMKPGQSYQNRNTRRDCCGFFQYRSKNILW
EEEECCCCHHHHHHHCCCCEEEEEEECCCCCCCCCCCHHCCCCHHHHHHHHHHCCCCEEE
NNCHIYYMHGMGVVSQFCENIMFSHLKIAPRPRSLRTNSSWADNLHFSGCRGKIIVKDCV
ECEEEEEEECHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCEECCCCCEEEEEEEE
LGASHDDAVNVHGTHLRIIDRPAPNKITVRFMHPQTFGFDAFAAGDRIDYVSCNTLVPYA
ECCCCCCEEEECCEEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCEEEEEECCEECCCC
SNTVSGVKQLNEKEIELTLQHPNPGNIQPDDVVENVTWTPSVHISNTVCRHIPTRGFLLT
CCHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHCCCCCCCEEECCHHHHHCCCCCEEEE
TRKPVLVERCRFEKTGMPAILVEDDASGWYESGVVRNMTISRNTFIQCGEAVIQIVPHAP
CCCCHHHHHHCCCCCCCCEEEEECCCCCHHHCCEEEEEEECCCHHHHHCCHHHEECCCCC
RPEGDVHRNITITGNTFDLKNGTAIRIRHTGDVKAEKNTFTKDGKKIPEEKAVDIR
CCCCCCEEEEEEECCEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQNPVASLLFILAMLTGPCPAADYPERTERTQSAGNHVWHIDPDKGNDGNPGTAPSTAWK
CCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCHHHH
SMAPANRLIMARGDTLVIHPGEHAVSLALMGEGSKQAPVTIRFMPGRHIFKHGALMTGKP
HCCCCCEEEEEECCEEEEECCCCEEEEEEECCCCCCCCEEEEECCCCHHHHCCCEEECCC
QISNTNDAPNEPKAMAIRLMEAKNIRLEGKPGATDILLEGKAIFVCMEHAENVSLNGLGF
CCCCCCCCCCCCCEEEEEEEECCCEEEECCCCCEEEEECCCEEEEEEECCCCCEECCCCC
DYLHPTMGEFLVTEVEGDTMKATIPDGTLYTVKDGNLTWHGPGWEFRMGGYSKVFDSASG
HHHCCCCCCEEEEEECCCEEEEECCCCEEEEEECCCEEECCCCEEEECCCHHHHHCCCCC
TFQGRFDPGKTVIRELSPGKISITFKEGSPTMKPGQSYQNRNTRRDCCGFFQYRSKNILW
EEEECCCCHHHHHHHCCCCEEEEEEECCCCCCCCCCCHHCCCCHHHHHHHHHHCCCCEEE
NNCHIYYMHGMGVVSQFCENIMFSHLKIAPRPRSLRTNSSWADNLHFSGCRGKIIVKDCV
ECEEEEEEECHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCEECCCCCEEEEEEEE
LGASHDDAVNVHGTHLRIIDRPAPNKITVRFMHPQTFGFDAFAAGDRIDYVSCNTLVPYA
ECCCCCCEEEECCEEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCEEEEEECCEECCCC
SNTVSGVKQLNEKEIELTLQHPNPGNIQPDDVVENVTWTPSVHISNTVCRHIPTRGFLLT
CCHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHCCCCCCCEEECCHHHHHCCCCCEEEE
TRKPVLVERCRFEKTGMPAILVEDDASGWYESGVVRNMTISRNTFIQCGEAVIQIVPHAP
CCCCHHHHHHCCCCCCCCEEEEECCCCCHHHCCEEEEEEECCCHHHHHCCHHHEECCCCC
RPEGDVHRNITITGNTFDLKNGTAIRIRHTGDVKAEKNTFTKDGKKIPEEKAVDIR
CCCCCCEEEEEEECCEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA