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The map label for this gene is kdpD [H]

Identifier: 187735648

GI number: 187735648

Start: 1384552

End: 1385679

Strand: Direct

Name: kdpD [H]

Synonym: Amuc_1154

Alternate gene names: 187735648

Gene position: 1384552-1385679 (Clockwise)

Preceding gene: 187735647

Following gene: 187735649

Centisome position: 51.97

GC content: 50.8

Gene sequence:

>1128_bases
ATGATTGACGGAAGTAACGGAGCAGAGCACTTTCTTGACCTGATACGGCGTTCTCGAAGGGGAAAGTTCAAGATTTACAT
TGGTATGATGGCCGGAGTAGGCAAGACGTACCGCATGCTGCAGGAAGCCCATGAATTGCTGAATAACGGCATTGATGTCA
GAATCGGTTACGTTGAAACCCACGGGCGGCCCGGGACTGAAGCCATGCTCCGGGGGGTGCCCGTCATCCCGCGTAAAGTG
GTTTTTTACAAAGGCAGGGAGATTGAAGAAATGGACCTGGACGCGATTCTTCAAGCCCGGCCCGAGTTGGTTATTGTTGA
CGAACTGGCTCATACCAATGTGGAAGGGAGCCGCCATCGCAAGAGATGGGAAGACGTGATGGAGCTGCTTGACGCCAATA
TTAATGTGATTTCCGCGATTAATATCCAGCATATCGAAAGCCTGAGCGGCGAAGTGAAGGAGATTACGGGGATTGAGATG
AAGGAACGGGTTCCCGACAGGATTTTGCAGGAGGCGGACGAAGTGGTGAATATCGACCTGACGTCCGAGGAATTGATCGG
CCGCCTCAAGGCCGGCAAGATTTACCGGCCTGAAAAAATCCAGATTGCCCTGGATAATTTTTTCAGAACGGAAAATATTC
TTCAGCTGCGTGAACTGGCATTGAAGGAAGTTGCTTTCCGAGTGGAGAAAAAAGTGGAAACGGAAGTATTCCCGGCAGTT
TCTTCCGCCAGAAGGGAAAAGATTCTGGCCTGCATCAGCAGCAATGAACAGACGCCCCGGCACATCATCCGAAAAGCATA
CCGGATTTCCTCGCGTTACAGTACGTCGTTTATCGCCCTTTACGTCCAGACGCCAAGGGAGTCCCCCGACCGCATCAATC
TGGCGTCCCAGCGCCATTTGCTTAATCATTTCAAGCTGGTGGCCGAACTGGGAGGGACGGTGAAGCAGGTGAGTGCGGAA
GACATACCCCAGGCGATCATCGCAACGTGCAGGGAATATCATATTACGGCTATTTGCATGGGGCATCCCGCATTCAAAAT
GCCCGGAGCCATGTTCAAGATACTGGGATATAAACAATTTCTGCGTGTCTTGTCGGAGATGAAGATAGATTTAATCATCA
TTGCATAA

Upstream 100 bases:

>100_bases
GGCTTCATGTCATGGTAACGCCCGCAATTGATTTTCATTTTCAAAAGATTCTGTAAAATCAACAAGATGTTTTTAACCGC
AGGAGCCGGGTGAATTTAAT

Downstream 100 bases:

>100_bases
AAAACAGAGGTAAATTTGAAAATAAGGCCGGAGCCGGTTCTTTTCACAGGAAGCAGGCGATGAGATTATCATGCTTGTCT
TCCCTGAGCGGAACGGATTG

Product: Osmosensitive K channel His kinase sensor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MIDGSNGAEHFLDLIRRSRRGKFKIYIGMMAGVGKTYRMLQEAHELLNNGIDVRIGYVETHGRPGTEAMLRGVPVIPRKV
VFYKGREIEEMDLDAILQARPELVIVDELAHTNVEGSRHRKRWEDVMELLDANINVISAINIQHIESLSGEVKEITGIEM
KERVPDRILQEADEVVNIDLTSEELIGRLKAGKIYRPEKIQIALDNFFRTENILQLRELALKEVAFRVEKKVETEVFPAV
SSARREKILACISSNEQTPRHIIRKAYRISSRYSTSFIALYVQTPRESPDRINLASQRHLLNHFKLVAELGGTVKQVSAE
DIPQAIIATCREYHITAICMGHPAFKMPGAMFKILGYKQFLRVLSEMKIDLIIIA

Sequences:

>Translated_375_residues
MIDGSNGAEHFLDLIRRSRRGKFKIYIGMMAGVGKTYRMLQEAHELLNNGIDVRIGYVETHGRPGTEAMLRGVPVIPRKV
VFYKGREIEEMDLDAILQARPELVIVDELAHTNVEGSRHRKRWEDVMELLDANINVISAINIQHIESLSGEVKEITGIEM
KERVPDRILQEADEVVNIDLTSEELIGRLKAGKIYRPEKIQIALDNFFRTENILQLRELALKEVAFRVEKKVETEVFPAV
SSARREKILACISSNEQTPRHIIRKAYRISSRYSTSFIALYVQTPRESPDRINLASQRHLLNHFKLVAELGGTVKQVSAE
DIPQAIIATCREYHITAICMGHPAFKMPGAMFKILGYKQFLRVLSEMKIDLIIIA
>Mature_375_residues
MIDGSNGAEHFLDLIRRSRRGKFKIYIGMMAGVGKTYRMLQEAHELLNNGIDVRIGYVETHGRPGTEAMLRGVPVIPRKV
VFYKGREIEEMDLDAILQARPELVIVDELAHTNVEGSRHRKRWEDVMELLDANINVISAINIQHIESLSGEVKEITGIEM
KERVPDRILQEADEVVNIDLTSEELIGRLKAGKIYRPEKIQIALDNFFRTENILQLRELALKEVAFRVEKKVETEVFPAV
SSARREKILACISSNEQTPRHIIRKAYRISSRYSTSFIALYVQTPRESPDRINLASQRHLLNHFKLVAELGGTVKQVSAE
DIPQAIIATCREYHITAICMGHPAFKMPGAMFKILGYKQFLRVLSEMKIDLIIIA

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon. KdpD may function as a membrane-associated protein kinase that phosphorylates kdpE in response to environmental signals [H]

COG id: COG2205

COG function: function code T; Osmosensitive K+ channel histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786912, Length=333, Percent_Identity=42.042042042042, Blast_Score=262, Evalue=3e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR003852
- InterPro:   IPR006016 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF02702 KdpD; PF00582 Usp [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 42737; Mature: 42737

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDGSNGAEHFLDLIRRSRRGKFKIYIGMMAGVGKTYRMLQEAHELLNNGIDVRIGYVET
CCCCCCCHHHHHHHHHHHCCCCEEEEEEEHHCCCHHHHHHHHHHHHHHCCCEEEEEEEEE
HGRPGTEAMLRGVPVIPRKVVFYKGREIEEMDLDAILQARPELVIVDELAHTNVEGSRHR
CCCCCHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCEEEEECHHHCCCCCHHHH
KRWEDVMELLDANINVISAINIQHIESLSGEVKEITGIEMKERVPDRILQEADEVVNIDL
HHHHHHHHHHCCCCCEEEECCHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHEEEEEC
TSEELIGRLKAGKIYRPEKIQIALDNFFRTENILQLRELALKEVAFRVEKKVETEVFPAV
CHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSARREKILACISSNEQTPRHIIRKAYRISSRYSTSFIALYVQTPRESPDRINLASQRHL
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCHHHHHHH
LNHFKLVAELGGTVKQVSAEDIPQAIIATCREYHITAICMGHPAFKMPGAMFKILGYKQF
HHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHEEEEEEECCCCHHCCHHHHHHHHHHHH
LRVLSEMKIDLIIIA
HHHHHHCCEEEEEEC
>Mature Secondary Structure
MIDGSNGAEHFLDLIRRSRRGKFKIYIGMMAGVGKTYRMLQEAHELLNNGIDVRIGYVET
CCCCCCCHHHHHHHHHHHCCCCEEEEEEEHHCCCHHHHHHHHHHHHHHCCCEEEEEEEEE
HGRPGTEAMLRGVPVIPRKVVFYKGREIEEMDLDAILQARPELVIVDELAHTNVEGSRHR
CCCCCHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCEEEEECHHHCCCCCHHHH
KRWEDVMELLDANINVISAINIQHIESLSGEVKEITGIEMKERVPDRILQEADEVVNIDL
HHHHHHHHHHCCCCCEEEECCHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHEEEEEC
TSEELIGRLKAGKIYRPEKIQIALDNFFRTENILQLRELALKEVAFRVEKKVETEVFPAV
CHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSARREKILACISSNEQTPRHIIRKAYRISSRYSTSFIALYVQTPRESPDRINLASQRHL
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCHHHHHHH
LNHFKLVAELGGTVKQVSAEDIPQAIIATCREYHITAICMGHPAFKMPGAMFKILGYKQF
HHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHEEEEEEECCCCHHCCHHHHHHHHHHHH
LRVLSEMKIDLIIIA
HHHHHHCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503; 7499326 [H]