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The map label for this gene is ribD [H]

Identifier: 187735315

GI number: 187735315

Start: 957476

End: 958546

Strand: Reverse

Name: ribD [H]

Synonym: Amuc_0813

Alternate gene names: 187735315

Gene position: 958546-957476 (Counterclockwise)

Preceding gene: 187735317

Following gene: 187735312

Centisome position: 35.98

GC content: 48.55

Gene sequence:

>1071_bases
ATGCTACAAAACGGCGTGAATACGAAAAATCAGGATGACTGTTGGATGAACATGGCCATAAAACTGGCCTCAAATGGAAT
TGGACTTACGAGTCCGAATCCCTGCGTGGGGGCAGTCATTGTGCATGAAAACCAGGTGATTGGTTCGGGATTTCATAAAA
AAGCCGGCTTGCCTCATGCGGAAAGAGAGGCCATTGCCGACGGAGTGGCGAATGGCAATGCCCCCCTGTTCGCGGACTCA
ACTTTGTATGTTACTCTGGAACCATGCAGTACTTCCGGGAAAACACCGCCTTGTACGGATGCCATTTTGAAATATCGTTT
CAAACGGGTAGTTTATGGTTCGGAAGATCCTAATCCCAAACACCGCGGCGCTGCGGCTGATATTCTTGAACAGGCCGGCA
TCAAGGTTACCCGCGGGGTTCTGGAGAAGGAATGTGATCGTTTAATCAGGAGGTTCAGAGTGAACATGCTGGAAGGGCGT
CCCTGGGTAATTGCAAAAAGCGCCATGTCTCTGGATGGCCGCATTTCCCGTAGTCCGGAACGTTCCCAATGGCTGACGAA
TGAAAAATCCAGATCTTTTGTACATACCCTGCGTGCCGAATGCGATGCGGTTCTTACCGGAGGGAATACCGTGCGTCTGG
ACAATCCGTCTCTGACCATTAGGAAACCGGATCGTCCTGTTTCTCCCCTTAAGGAACAACCCTGGCGTATTATTCTAACC
CATGATGCCTCTTCCATACCTGCGGATTCCATTTGTTTAACAGATGAATTTCGTGACCGCACTTTGGTTGTGGAGAATGT
TTTTAGTTATTTGGAATTATTAAAAAAATTATATAATGATAAAAAAATAGGAACTATCCTGCTGGAAGCGGGAGGCTGTC
TGGTCCGGGAATTTCTGAAAGCCGGTTTAGTCGACGAGTGGGTGGGGTTTTATGCTCCCATCATTATCGGCGGCGGTGCG
GACGGCGTAGCGCCCGGTCCGTTTCTGGAGCATGAAGCCCATCTTGAACAACCTGTTGTAAATATTTTTGGAGGTGATGT
ATGTATCCGGGGAGATATCTGTTACCGGTAA

Upstream 100 bases:

>100_bases
CTTATTCACACTAGGCACACAGTAGAAGAAGAAGGAATTTAATATTGTTAAACCTAATATTCTTCAATCACACAACGTGA
TTGTCCTTCTTCCGGTTTTC

Downstream 100 bases:

>100_bases
TGGATAAGGTCTTTTGTTTATTGGTTATCCGAAGAATTTTAAACTTGGGAAGGTAATTTTCATTAGCCCGGTGGATTTGT
CATTCAGCCCTTCCGGCCTC

Product: riboflavin biosynthesis protein RibD

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MLQNGVNTKNQDDCWMNMAIKLASNGIGLTSPNPCVGAVIVHENQVIGSGFHKKAGLPHAEREAIADGVANGNAPLFADS
TLYVTLEPCSTSGKTPPCTDAILKYRFKRVVYGSEDPNPKHRGAAADILEQAGIKVTRGVLEKECDRLIRRFRVNMLEGR
PWVIAKSAMSLDGRISRSPERSQWLTNEKSRSFVHTLRAECDAVLTGGNTVRLDNPSLTIRKPDRPVSPLKEQPWRIILT
HDASSIPADSICLTDEFRDRTLVVENVFSYLELLKKLYNDKKIGTILLEAGGCLVREFLKAGLVDEWVGFYAPIIIGGGA
DGVAPGPFLEHEAHLEQPVVNIFGGDVCIRGDICYR

Sequences:

>Translated_356_residues
MLQNGVNTKNQDDCWMNMAIKLASNGIGLTSPNPCVGAVIVHENQVIGSGFHKKAGLPHAEREAIADGVANGNAPLFADS
TLYVTLEPCSTSGKTPPCTDAILKYRFKRVVYGSEDPNPKHRGAAADILEQAGIKVTRGVLEKECDRLIRRFRVNMLEGR
PWVIAKSAMSLDGRISRSPERSQWLTNEKSRSFVHTLRAECDAVLTGGNTVRLDNPSLTIRKPDRPVSPLKEQPWRIILT
HDASSIPADSICLTDEFRDRTLVVENVFSYLELLKKLYNDKKIGTILLEAGGCLVREFLKAGLVDEWVGFYAPIIIGGGA
DGVAPGPFLEHEAHLEQPVVNIFGGDVCIRGDICYR
>Mature_356_residues
MLQNGVNTKNQDDCWMNMAIKLASNGIGLTSPNPCVGAVIVHENQVIGSGFHKKAGLPHAEREAIADGVANGNAPLFADS
TLYVTLEPCSTSGKTPPCTDAILKYRFKRVVYGSEDPNPKHRGAAADILEQAGIKVTRGVLEKECDRLIRRFRVNMLEGR
PWVIAKSAMSLDGRISRSPERSQWLTNEKSRSFVHTLRAECDAVLTGGNTVRLDNPSLTIRKPDRPVSPLKEQPWRIILT
HDASSIPADSICLTDEFRDRTLVVENVFSYLELLKKLYNDKKIGTILLEAGGCLVREFLKAGLVDEWVGFYAPIIIGGGA
DGVAPGPFLEHEAHLEQPVVNIFGGDVCIRGDICYR

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG0117

COG function: function code H; Pyrimidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=368, Percent_Identity=36.1413043478261, Blast_Score=202, Evalue=2e-53,
Organism=Escherichia coli, GI145693172, Length=148, Percent_Identity=34.4594594594595, Blast_Score=76, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 39087; Mature: 39087

Theoretical pI: Translated: 7.43; Mature: 7.43

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQNGVNTKNQDDCWMNMAIKLASNGIGLTSPNPCVGAVIVHENQVIGSGFHKKAGLPHA
CCCCCCCCCCCCHHHHHHEEEEECCCCCCCCCCCCEEEEEEECCEEECCCCHHHCCCCHH
EREAIADGVANGNAPLFADSTLYVTLEPCSTSGKTPPCTDAILKYRFKRVVYGSEDPNPK
HHHHHHHHCCCCCCCEEECCEEEEEEECCCCCCCCCCHHHHHHHHHHHHEEECCCCCCCC
HRGAAADILEQAGIKVTRGVLEKECDRLIRRFRVNMLEGRPWVIAKSAMSLDGRISRSPE
CCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCC
RSQWLTNEKSRSFVHTLRAECDAVLTGGNTVRLDNPSLTIRKPDRPVSPLKEQPWRIILT
HHHHHCCHHHHHHHHHHHHCCCEEEECCCEEEECCCEEEEECCCCCCCCHHCCCCEEEEE
HDASSIPADSICLTDEFRDRTLVVENVFSYLELLKKLYNDKKIGTILLEAGGCLVREFLK
ECCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHH
AGLVDEWVGFYAPIIIGGGADGVAPGPFLEHEAHLEQPVVNIFGGDVCIRGDICYR
CCCHHHHHHHHEEEEEECCCCCCCCCCCCCCHHHHHCCHHHHCCCCEEEECCCCCC
>Mature Secondary Structure
MLQNGVNTKNQDDCWMNMAIKLASNGIGLTSPNPCVGAVIVHENQVIGSGFHKKAGLPHA
CCCCCCCCCCCCHHHHHHEEEEECCCCCCCCCCCCEEEEEEECCEEECCCCHHHCCCCHH
EREAIADGVANGNAPLFADSTLYVTLEPCSTSGKTPPCTDAILKYRFKRVVYGSEDPNPK
HHHHHHHHCCCCCCCEEECCEEEEEEECCCCCCCCCCHHHHHHHHHHHHEEECCCCCCCC
HRGAAADILEQAGIKVTRGVLEKECDRLIRRFRVNMLEGRPWVIAKSAMSLDGRISRSPE
CCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCC
RSQWLTNEKSRSFVHTLRAECDAVLTGGNTVRLDNPSLTIRKPDRPVSPLKEQPWRIILT
HHHHHCCHHHHHHHHHHHHCCCEEEECCCEEEECCCEEEEECCCCCCCCHHCCCCEEEEE
HDASSIPADSICLTDEFRDRTLVVENVFSYLELLKKLYNDKKIGTILLEAGGCLVREFLK
ECCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHH
AGLVDEWVGFYAPIIIGGGADGVAPGPFLEHEAHLEQPVVNIFGGDVCIRGDICYR
CCCHHHHHHHHEEEEEECCCCCCCCCCCCCCHHHHHCCHHHHCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]