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The map label for this gene is gluP [H]

Identifier: 187735290

GI number: 187735290

Start: 923535

End: 924410

Strand: Direct

Name: gluP [H]

Synonym: Amuc_0787

Alternate gene names: 187735290

Gene position: 923535-924410 (Clockwise)

Preceding gene: 187735289

Following gene: 187735291

Centisome position: 34.67

GC content: 54.45

Gene sequence:

>876_bases
ATGCGAGCGGAGAACGAGAACTGGGGAGATACGGTACGGAATCATCTGTTTGACCAGCGCAGCGCCGTCATGGTGCACTG
GCTGATTCTGCTCAATGTAGTCATCTTTATCCTGGGATTCTTCTTCCAAGTGGACATCCCAAGGAATATTTACCCGCCTG
TCCATTTGGACTTGATCCAGCTTTACGGAGCTTACAGCGAATATACGTGCTTTCACGAGGGGGAATTATGGCGGTTGCTT
ACCTATCAGTTTCTTCACGCCAATCTGGGGCACATCATGTTCAACATGATTGCCCTGTGGTTTTTCGGCCCGGTTGTAGA
AGAACGTTTCGGCCATTGGCGCTTCCTGCTGTATTACCTGTTTTGCGGCGTGGCTGCAGCCCTGTTTTCCTCCCTGCTGG
GGTACATGGGATTTTTTGATCCGGAATGGCGCTTCATTCCCATGGTGGGGGCCTCAGGTTCCATTTACGGCATCATGGCC
GCATGCGCGGTGCTCTTTCCCCATGCCCGGGTACAGCTTCTGTTTCCTCCGGTTAATTTGAGCGTGCGCCAGTTTGCCCT
GGCCGTTCTCGGAGTCGCCGCAGCCGTCATTATCTTCCAATGGAACAATGCGGGCGGGGAAGCCGGCCATCTGGGCGGCA
TGTTCGCCGGATTTATTCTGACATTGCTGATTTTATGGAAGGAAAAGATGTCTTCCCCAAGACGGAAAGCCGCCTCTTCT
TCCCACTATTCCCCTGAGCCTTCCAGCCGCCGCCCGGCACAGGCTTACCCCTCTGAAAAGGAGGTGGATGAAATCATGGA
AAAAATATCCAGGTCCGGCCTGTCCAGCCTGACGGAGGAGGAACGGGAAATTCTCCGGCGCGCTTCCCGGCGCTGA

Upstream 100 bases:

>100_bases
CGCGCTCTGGAAATGATACGGAACATCAGCTGTCCTTCCTTGAACGGAACAGCTATTTTCCTTGTCAAAAGGTTCTGAAC
GCGATTACATGCGGCCTAAT

Downstream 100 bases:

>100_bases
ACTATTTGTTAGATATTTTTATATTTTTCGTTATTTTCCTTCCTTTTTGCCATCCATTTCCTAGCATGGATGAATGATGA
CGCGACTGTATTCCTCCACC

Product: Rhomboid family protein

Products: NA

Alternate protein names: Intramembrane serine protease [H]

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MRAENENWGDTVRNHLFDQRSAVMVHWLILLNVVIFILGFFFQVDIPRNIYPPVHLDLIQLYGAYSEYTCFHEGELWRLL
TYQFLHANLGHIMFNMIALWFFGPVVEERFGHWRFLLYYLFCGVAAALFSSLLGYMGFFDPEWRFIPMVGASGSIYGIMA
ACAVLFPHARVQLLFPPVNLSVRQFALAVLGVAAAVIIFQWNNAGGEAGHLGGMFAGFILTLLILWKEKMSSPRRKAASS
SHYSPEPSSRRPAQAYPSEKEVDEIMEKISRSGLSSLTEEEREILRRASRR

Sequences:

>Translated_291_residues
MRAENENWGDTVRNHLFDQRSAVMVHWLILLNVVIFILGFFFQVDIPRNIYPPVHLDLIQLYGAYSEYTCFHEGELWRLL
TYQFLHANLGHIMFNMIALWFFGPVVEERFGHWRFLLYYLFCGVAAALFSSLLGYMGFFDPEWRFIPMVGASGSIYGIMA
ACAVLFPHARVQLLFPPVNLSVRQFALAVLGVAAAVIIFQWNNAGGEAGHLGGMFAGFILTLLILWKEKMSSPRRKAASS
SHYSPEPSSRRPAQAYPSEKEVDEIMEKISRSGLSSLTEEEREILRRASRR
>Mature_291_residues
MRAENENWGDTVRNHLFDQRSAVMVHWLILLNVVIFILGFFFQVDIPRNIYPPVHLDLIQLYGAYSEYTCFHEGELWRLL
TYQFLHANLGHIMFNMIALWFFGPVVEERFGHWRFLLYYLFCGVAAALFSSLLGYMGFFDPEWRFIPMVGASGSIYGIMA
ACAVLFPHARVQLLFPPVNLSVRQFALAVLGVAAAVIIFQWNNAGGEAGHLGGMFAGFILTLLILWKEKMSSPRRKAASS
SHYSPEPSSRRPAQAYPSEKEVDEIMEKISRSGLSSLTEEEREILRRASRR

Specific function: Rhomboid-type serine protease that catalyzes intramembrane proteolysis. Important for normal cell division and sporulation. May act as a glucose exporter [H]

COG id: COG0705

COG function: function code R; Uncharacterized membrane protein (homolog of Drosophila rhomboid)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 TPR repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002610
- InterPro:   IPR022764
- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF01694 Rhomboid; PF00515 TPR_1 [H]

EC number: =3.4.21.105 [H]

Molecular weight: Translated: 33263; Mature: 33263

Theoretical pI: Translated: 7.71; Mature: 7.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAENENWGDTVRNHLFDQRSAVMVHWLILLNVVIFILGFFFQVDIPRNIYPPVHLDLIQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
LYGAYSEYTCFHEGELWRLLTYQFLHANLGHIMFNMIALWFFGPVVEERFGHWRFLLYYL
HHCCHHHCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FCGVAAALFSSLLGYMGFFDPEWRFIPMVGASGSIYGIMAACAVLFPHARVQLLFPPVNL
HHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCEEEEECCCCH
SVRQFALAVLGVAAAVIIFQWNNAGGEAGHLGGMFAGFILTLLILWKEKMSSPRRKAASS
HHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCC
SHYSPEPSSRRPAQAYPSEKEVDEIMEKISRSGLSSLTEEEREILRRASRR
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRAENENWGDTVRNHLFDQRSAVMVHWLILLNVVIFILGFFFQVDIPRNIYPPVHLDLIQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
LYGAYSEYTCFHEGELWRLLTYQFLHANLGHIMFNMIALWFFGPVVEERFGHWRFLLYYL
HHCCHHHCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FCGVAAALFSSLLGYMGFFDPEWRFIPMVGASGSIYGIMAACAVLFPHARVQLLFPPVNL
HHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCEEEEECCCCH
SVRQFALAVLGVAAAVIIFQWNNAGGEAGHLGGMFAGFILTLLILWKEKMSSPRRKAASS
HHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCC
SHYSPEPSSRRPAQAYPSEKEVDEIMEKISRSGLSSLTEEEREILRRASRR
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]