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The map label for this gene is bga [H]

Identifier: 187735275

GI number: 187735275

Start: 906706

End: 908637

Strand: Reverse

Name: bga [H]

Synonym: Amuc_0771

Alternate gene names: 187735275

Gene position: 908637-906706 (Counterclockwise)

Preceding gene: 187735279

Following gene: 187735273

Centisome position: 34.11

GC content: 55.64

Gene sequence:

>1932_bases
ATGATGAAGCAATATGGTTTCAGTTGGTCTGCCGCACTGATGGCCGTCGGAGTGGGAGCATTGGCATGGGCTGGCCCTGA
GGCTGTCCAGAATGTACAGAAACCCGCTCTTTCCGGAGGACCCCCCGTTGTGTTCGGGTTCGGCGGGGAAGGGAACCAGG
AGTTCATGCTGAACGGGAAACCCTTCCAGATCCGCGGCGCGGAGATGCATCCCCAGCGCATTCCCCGGGAATACTGGAGG
CACCGCATCAGGACCGCCAAGGCTATGGGGCTGAATACTATTGCATTTTATGTGTTCTGGAATGACCATGAGCAGCCGGA
CGGCAGCTTTGACTTTAAGACGGGCAATCGGGATCTGGAAGGGTTCCTCAAGTTATGCCAGGAGGAAGGAATGTGGGTTT
TATTCCGCCCCGGCCCCTATGCATGCGGGGAATGGGATCTGGGTGGGCTGCCTCATTATTTGCTGAAGGATCCCAAGGCC
AAGTTGAGAACTACGGAAGACGCCAAATTCATGAAGGCGCAGACGCGTTATCTGGAGGCCGTGGCTCGTGTGGCGGAGCC
TTTTTTAGCCAAAAACGGGGGCCCCATTCTGATGACCCAGCTTGAAAACGAATACGGGAGCTACCAGCGTAAAGACCGCA
AGTATATGGAATGGCTGAAGGCGTTCTGGAGCAGGAAGGGTTTTGGCCCCTTTTACACCTCCGACGGCGCGGGAGAACAT
TTTCTGAAAGGCGTGGTGCTTCCAGGCGTGGCCGTAGGGCTGGATCCGGGGCTGAACGACGGCCATTGGGCAGTGGCTAA
TAAATGCAATCCGGGAGTTCCCGTTTTTTCCTCGGAAACATATCCGGGTTGGCTGCGGCACTGGGGGGAGGGGAATTGGG
CTCCCACCCCTGGAGTGGTCAACCACGTCCGCTGGTTTATGGACAAGGGGCGTTCCTTCAGCTTGTTCGTTTTCCACGGA
GGCACCAATTTCGGATTCTCGGCCGGAGCCAACAACGGAGGGCCGGGAAAATACCAGCCGGACCTGACGAGTTATGATTA
CGGTTCTCCCGTGGATGAGCAGGGGCGGATGAATGAATATTATGCCCAGATGAGGGAAATCATTTTGAAAAAGTTGCCTC
CCGAAGCCGCTGTGCCGGAACCTCCCGCAGACATTCCGGCCATGGAAATTCCGGAGTTCACGCCCGCAGTGCATGCCGGC
CTTTGGGAGAACCTGCCCAAGCCTTTCCGGTCCAAGTTCCCGCAGCCTCCCTATTTTGAACAATGGAACCAGAACCAGGG
TATTGCCGTTTACAGAACGGCCGTTCCGTCAGGACCGCCTGAAACGCTGGAATTTACCAATGTCAATGACTATGCCCAGG
TGTATCTGGATGGAGAGCTGGTCGGCACGCTGGATCGGCGGCTGGGGCAGAAGAGCGTGAAACTGCCGGAGCGCAGGAAG
CCGGGGACGCTGGAAGTTCTGGTAGAGGCCATGGGACATATTAATTTTCATATCAGCATGGAGAGTGACCGCAAGGGGAT
TTACGGTCCTGTGAAGCTGGGAACGCGGGAGTTAAAGAACTGGACGGTGAGGGCGCTTCCCCTGAAAGCTGATTCCATTG
TGCGGGCTCCCAAAGGAAAGGGGCCTTCCCAGAAACGGGAAGGGGCGCATTTCCGGGCCGTTGTAAATATTGAAGAGCCT
CAGGACACGTTTCTGGATATGTCCCGCTATGTCAAGGGGTATGTATGGGTGAACGGAATCAACGTGGGGCGCTATTGGAA
TGTGGGACCTCAGTTAAGGCTGTATGTCCCGGCCCCATTCCTGAAAAAAGGGGAGAATGTGATTGATATTCTGGACCTGC
ACGAAAAGGAGCCCAAGCCTGTCCGCGGCATGAAGGAACGCAACAAGGAACCCGGAAAGATAAATACCAAAAACCTGGAC
AACCAGTGGTAA

Upstream 100 bases:

>100_bases
CGTCAGATTTCTGGCGGAGGGGAAGGGTATTCCGAAGATTCGGAGAAGAGAGAAAAAAATTGTTATTGGCAACCGTCTTC
AAATGAATTAACTGTTCAAC

Downstream 100 bases:

>100_bases
TGCTGGTGCGTTTTCCGCTTGCGGTTCCGGATTTTCCATGAATTTGAACTATGGGAAAGACCGCAAGCGGGGAGTAGATT
TCCTGGCGCCGCAGTTTCCC

Product: Beta-galactosidase

Products: NA

Alternate protein names: Lactase [H]

Number of amino acids: Translated: 643; Mature: 643

Protein sequence:

>643_residues
MMKQYGFSWSAALMAVGVGALAWAGPEAVQNVQKPALSGGPPVVFGFGGEGNQEFMLNGKPFQIRGAEMHPQRIPREYWR
HRIRTAKAMGLNTIAFYVFWNDHEQPDGSFDFKTGNRDLEGFLKLCQEEGMWVLFRPGPYACGEWDLGGLPHYLLKDPKA
KLRTTEDAKFMKAQTRYLEAVARVAEPFLAKNGGPILMTQLENEYGSYQRKDRKYMEWLKAFWSRKGFGPFYTSDGAGEH
FLKGVVLPGVAVGLDPGLNDGHWAVANKCNPGVPVFSSETYPGWLRHWGEGNWAPTPGVVNHVRWFMDKGRSFSLFVFHG
GTNFGFSAGANNGGPGKYQPDLTSYDYGSPVDEQGRMNEYYAQMREIILKKLPPEAAVPEPPADIPAMEIPEFTPAVHAG
LWENLPKPFRSKFPQPPYFEQWNQNQGIAVYRTAVPSGPPETLEFTNVNDYAQVYLDGELVGTLDRRLGQKSVKLPERRK
PGTLEVLVEAMGHINFHISMESDRKGIYGPVKLGTRELKNWTVRALPLKADSIVRAPKGKGPSQKREGAHFRAVVNIEEP
QDTFLDMSRYVKGYVWVNGINVGRYWNVGPQLRLYVPAPFLKKGENVIDILDLHEKEPKPVRGMKERNKEPGKINTKNLD
NQW

Sequences:

>Translated_643_residues
MMKQYGFSWSAALMAVGVGALAWAGPEAVQNVQKPALSGGPPVVFGFGGEGNQEFMLNGKPFQIRGAEMHPQRIPREYWR
HRIRTAKAMGLNTIAFYVFWNDHEQPDGSFDFKTGNRDLEGFLKLCQEEGMWVLFRPGPYACGEWDLGGLPHYLLKDPKA
KLRTTEDAKFMKAQTRYLEAVARVAEPFLAKNGGPILMTQLENEYGSYQRKDRKYMEWLKAFWSRKGFGPFYTSDGAGEH
FLKGVVLPGVAVGLDPGLNDGHWAVANKCNPGVPVFSSETYPGWLRHWGEGNWAPTPGVVNHVRWFMDKGRSFSLFVFHG
GTNFGFSAGANNGGPGKYQPDLTSYDYGSPVDEQGRMNEYYAQMREIILKKLPPEAAVPEPPADIPAMEIPEFTPAVHAG
LWENLPKPFRSKFPQPPYFEQWNQNQGIAVYRTAVPSGPPETLEFTNVNDYAQVYLDGELVGTLDRRLGQKSVKLPERRK
PGTLEVLVEAMGHINFHISMESDRKGIYGPVKLGTRELKNWTVRALPLKADSIVRAPKGKGPSQKREGAHFRAVVNIEEP
QDTFLDMSRYVKGYVWVNGINVGRYWNVGPQLRLYVPAPFLKKGENVIDILDLHEKEPKPVRGMKERNKEPGKINTKNLD
NQW
>Mature_643_residues
MMKQYGFSWSAALMAVGVGALAWAGPEAVQNVQKPALSGGPPVVFGFGGEGNQEFMLNGKPFQIRGAEMHPQRIPREYWR
HRIRTAKAMGLNTIAFYVFWNDHEQPDGSFDFKTGNRDLEGFLKLCQEEGMWVLFRPGPYACGEWDLGGLPHYLLKDPKA
KLRTTEDAKFMKAQTRYLEAVARVAEPFLAKNGGPILMTQLENEYGSYQRKDRKYMEWLKAFWSRKGFGPFYTSDGAGEH
FLKGVVLPGVAVGLDPGLNDGHWAVANKCNPGVPVFSSETYPGWLRHWGEGNWAPTPGVVNHVRWFMDKGRSFSLFVFHG
GTNFGFSAGANNGGPGKYQPDLTSYDYGSPVDEQGRMNEYYAQMREIILKKLPPEAAVPEPPADIPAMEIPEFTPAVHAG
LWENLPKPFRSKFPQPPYFEQWNQNQGIAVYRTAVPSGPPETLEFTNVNDYAQVYLDGELVGTLDRRLGQKSVKLPERRK
PGTLEVLVEAMGHINFHISMESDRKGIYGPVKLGTRELKNWTVRALPLKADSIVRAPKGKGPSQKREGAHFRAVVNIEEP
QDTFLDMSRYVKGYVWVNGINVGRYWNVGPQLRLYVPAPFLKKGENVIDILDLHEKEPKPVRGMKERNKEPGKINTKNLD
NQW

Specific function: Preferentially hydrolyzes beta(1->3) galactosyl linkages over beta(1->4) linkages [H]

COG id: COG1874

COG function: function code G; Beta-galactosidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 35 family [H]

Homologues:

Organism=Homo sapiens, GI164519026, Length=576, Percent_Identity=33.8541666666667, Blast_Score=314, Evalue=2e-85,
Organism=Homo sapiens, GI119372308, Length=600, Percent_Identity=35.5, Blast_Score=297, Evalue=2e-80,
Organism=Homo sapiens, GI119372312, Length=600, Percent_Identity=35.5, Blast_Score=297, Evalue=2e-80,
Organism=Homo sapiens, GI31543093, Length=577, Percent_Identity=34.8353552859619, Blast_Score=294, Evalue=2e-79,
Organism=Homo sapiens, GI40255043, Length=616, Percent_Identity=34.2532467532467, Blast_Score=266, Evalue=7e-71,
Organism=Homo sapiens, GI208022658, Length=378, Percent_Identity=34.6560846560847, Blast_Score=157, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI72000600, Length=603, Percent_Identity=33.4991708126036, Blast_Score=285, Evalue=5e-77,
Organism=Caenorhabditis elegans, GI17568491, Length=599, Percent_Identity=27.7128547579299, Blast_Score=213, Evalue=3e-55,
Organism=Drosophila melanogaster, GI24582088, Length=616, Percent_Identity=36.6883116883117, Blast_Score=311, Evalue=7e-85,
Organism=Drosophila melanogaster, GI24646169, Length=600, Percent_Identity=34.5, Blast_Score=300, Evalue=3e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008979
- InterPro:   IPR019801
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR001944 [H]

Pfam domain/function: PF01301 Glyco_hydro_35 [H]

EC number: =3.2.1.23 [H]

Molecular weight: Translated: 72407; Mature: 72407

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: PS01182 GLYCOSYL_HYDROL_F35

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKQYGFSWSAALMAVGVGALAWAGPEAVQNVQKPALSGGPPVVFGFGGEGNQEFMLNGK
CCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEECCC
PFQIRGAEMHPQRIPREYWRHRIRTAKAMGLNTIAFYVFWNDHEQPDGSFDFKTGNRDLE
CEEEECCCCCHHHCCHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCEECCCCCCCHH
GFLKLCQEEGMWVLFRPGPYACGEWDLGGLPHYLLKDPKAKLRTTEDAKFMKAQTRYLEA
HHHHHHHHCCCEEEECCCCCCCCCCCCCCCCHHHHCCCHHHCCCCCHHHHHHHHHHHHHH
VARVAEPFLAKNGGPILMTQLENEYGSYQRKDRKYMEWLKAFWSRKGFGPFYTSDGAGEH
HHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHH
FLKGVVLPGVAVGLDPGLNDGHWAVANKCNPGVPVFSSETYPGWLRHWGEGNWAPTPGVV
HHHHHHCCCEEEECCCCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCHHH
NHVRWFMDKGRSFSLFVFHGGTNFGFSAGANNGGPGKYQPDLTSYDYGSPVDEQGRMNEY
HHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
YAQMREIILKKLPPEAAVPEPPADIPAMEIPEFTPAVHAGLWENLPKPFRSKFPQPPYFE
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHCCCCCCCHH
QWNQNQGIAVYRTAVPSGPPETLEFTNVNDYAQVYLDGELVGTLDRRLGQKSVKLPERRK
HCCCCCCEEEEEECCCCCCCCCEEECCCCCEEEEEECCHHHHHHHHHCCCHHCCCCCCCC
PGTLEVLVEAMGHINFHISMESDRKGIYGPVKLGTRELKNWTVRALPLKADSIVRAPKGK
CCHHHHHHHHHCCEEEEEEECCCCCCCCCCHHHCHHHHCCCEEEEEEECCHHHEECCCCC
GPSQKREGAHFRAVVNIEEPQDTFLDMSRYVKGYVWVNGINVGRYWNVGPQLRLYVPAPF
CCCCCCCCCEEEEEEEECCCHHHHHHHHHHHEEEEEEEEEEECCEECCCCCEEEEECCHH
LKKGENVIDILDLHEKEPKPVRGMKERNKEPGKINTKNLDNQW
HHCCCCEEEEECCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MMKQYGFSWSAALMAVGVGALAWAGPEAVQNVQKPALSGGPPVVFGFGGEGNQEFMLNGK
CCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEECCC
PFQIRGAEMHPQRIPREYWRHRIRTAKAMGLNTIAFYVFWNDHEQPDGSFDFKTGNRDLE
CEEEECCCCCHHHCCHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCEECCCCCCCHH
GFLKLCQEEGMWVLFRPGPYACGEWDLGGLPHYLLKDPKAKLRTTEDAKFMKAQTRYLEA
HHHHHHHHCCCEEEECCCCCCCCCCCCCCCCHHHHCCCHHHCCCCCHHHHHHHHHHHHHH
VARVAEPFLAKNGGPILMTQLENEYGSYQRKDRKYMEWLKAFWSRKGFGPFYTSDGAGEH
HHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHH
FLKGVVLPGVAVGLDPGLNDGHWAVANKCNPGVPVFSSETYPGWLRHWGEGNWAPTPGVV
HHHHHHCCCEEEECCCCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCHHH
NHVRWFMDKGRSFSLFVFHGGTNFGFSAGANNGGPGKYQPDLTSYDYGSPVDEQGRMNEY
HHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
YAQMREIILKKLPPEAAVPEPPADIPAMEIPEFTPAVHAGLWENLPKPFRSKFPQPPYFE
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHCCCCCCCHH
QWNQNQGIAVYRTAVPSGPPETLEFTNVNDYAQVYLDGELVGTLDRRLGQKSVKLPERRK
HCCCCCCEEEEEECCCCCCCCCEEECCCCCEEEEEECCHHHHHHHHHCCCHHCCCCCCCC
PGTLEVLVEAMGHINFHISMESDRKGIYGPVKLGTRELKNWTVRALPLKADSIVRAPKGK
CCHHHHHHHHHCCEEEEEEECCCCCCCCCCHHHCHHHHCCCEEEEEEECCHHHEECCCCC
GPSQKREGAHFRAVVNIEEPQDTFLDMSRYVKGYVWVNGINVGRYWNVGPQLRLYVPAPF
CCCCCCCCCEEEEEEEECCCHHHHHHHHHHHEEEEEEEEEEECCEECCCCCEEEEECCHH
LKKGENVIDILDLHEKEPKPVRGMKERNKEPGKINTKNLDNQW
HHCCCCEEEEECCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8563148 [H]