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The map label for this gene is degP [H]

Identifier: 187735175

GI number: 187735175

Start: 786682

End: 788256

Strand: Direct

Name: degP [H]

Synonym: Amuc_0669

Alternate gene names: 187735175

Gene position: 786682-788256 (Clockwise)

Preceding gene: 187735174

Following gene: 187735176

Centisome position: 29.53

GC content: 56.63

Gene sequence:

>1575_bases
ATGATACATTCCCACACCTGTTTTCAAGGGCTGTGCGCAGTCCTGGCCGGCACCGCTCTTTCCCACGCGGATGAGCCGGC
TGTTTCCATTTCGGACTTCGGGGTAGATAAGGTCATGTCCGGCCCTGTCGTTTCCATCAATGATCAGTACAAGGGCGTCG
TGAAAATTGAGATGGATTCCCTGACTCCGGATTACGCTACTCCGTGGAATACCGGCCGCTACCAGGGGGGCATCGGCACC
GGCTTTCTGATCGGGGAAAACGCCTTCATGACGAACGCCCATGTAGTCAGCAACGCGGAACGCATTTATATCTCCATGTA
CGGAGATTCCCGTAAAATTCCCGCCAGGGTCAAATTCATCGCCCATGACGCGGATCTTGCTCTGCTGGAGGCGGACGATC
CCAGGCCCTTCAAAGGAATACGGCCTTTTGAATTCAGCAAAAACCTGCCTCATCTGGAAGACGAAGTAAGGGTGATCGGC
TACCCCATCGGCGGCAACAGGCTTTCCGTCACACGCGGCGTGGTCTCCCGCATTGATTTCACCACGTACGCCCACCCCCG
CAACACGGAACACCTGACCATCCAGGTGGACGCCGCCATTAACCCGGGCAACAGCGGTGGCCCCGTCCTGATGGGGAATA
AAGTCATCGGCGTGGCATTCCAGGGCCTGAACAACGCCAATAACACGGGGTACGTGATTCCAACCCCCGTCATCCGCCAC
TTTCTGGAAGACATCAAGGACGGTGTCTATGATGGTTACGTGGACATGGGCATTCAGGCTGCGCCCATCCTGAACCCGGC
CATGCGCAAGGCGTTCGGCCTGCCGGACGACGAAAAAGGCGTCCTGATCGGCAAGGTGCTCAAGGGGTCCTCCGCCGACG
GCGTGCTCCGCAACGGGGACCTGCTGATGAAAGTGGACGGCTATGATGTGGACAGTTCCGCCATGATTGAACTGGACGGC
CAGAAAATCAGTATGAAAGAACTCATTGAGCGCTGTTTTAAAGACGACCGGCTCCCGCTGGATATCATTCGCGACGGCAA
GCCCATGAAGGTGGAAATGGTGATGAAGCCATCCCCCTCCAGAGACCTTCTGATGGCGGAATACGATAAAATGCCCCGCT
ACGTCGTCTTTGGAGGCCTGGTGTTCCAGCCCATCCAGCGCAACGTGCTCGCGGCGGCGGACATCTCCATGCTGGACGTT
GCACTGGACATCCGGAATTACCAGGAAGACGGCGGCTGCGTGGACCATGAAGACATGGTCATCATCACCAAAGTGCTGGA
TGATGAGGTAAACGCGCGTCTGTCCGGCTCCATTTCCAATTCCATTGTGGAAAAAATCAACGGCGTAAAGGTTAAAGGCC
TTACCCACGCCTACGAACTCCTTTACCCGGAAAACATGCCGGAATACGTCGTCATCGAACTGAAAAACGGAGAGCGCCCC
CTCGTCTTTGAAGGCAAGGCCATGGAGACGGCCAACAAGCGTATCTCCAAAACCTACAATATCCCGAAAAACGCCCGCTT
GGACAGCGCCATTCCCGGCCGCCAGCCTGGCCGCAACACCACTCCCGCCCGTTAA

Upstream 100 bases:

>100_bases
AGGAAGTCAATTCCTTCCAGGAAAGCCTGGCAACACAAAGCCGCAAAAGCAACCTGTAACAACAAAACCTTCCCTGGCAA
CACAATCTTCATCTTTGCGT

Downstream 100 bases:

>100_bases
CCGCCATGAAAATTCTTTCCACTTTTTTCCTCGGTTCCCTGATGTTGCTCGGCGGCTGCCAGCCGCGCGAAGCCGGACGA
ACCGCTCCCGAACCCCAGCC

Product: 2-alkenal reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 524; Mature: 524

Protein sequence:

>524_residues
MIHSHTCFQGLCAVLAGTALSHADEPAVSISDFGVDKVMSGPVVSINDQYKGVVKIEMDSLTPDYATPWNTGRYQGGIGT
GFLIGENAFMTNAHVVSNAERIYISMYGDSRKIPARVKFIAHDADLALLEADDPRPFKGIRPFEFSKNLPHLEDEVRVIG
YPIGGNRLSVTRGVVSRIDFTTYAHPRNTEHLTIQVDAAINPGNSGGPVLMGNKVIGVAFQGLNNANNTGYVIPTPVIRH
FLEDIKDGVYDGYVDMGIQAAPILNPAMRKAFGLPDDEKGVLIGKVLKGSSADGVLRNGDLLMKVDGYDVDSSAMIELDG
QKISMKELIERCFKDDRLPLDIIRDGKPMKVEMVMKPSPSRDLLMAEYDKMPRYVVFGGLVFQPIQRNVLAAADISMLDV
ALDIRNYQEDGGCVDHEDMVIITKVLDDEVNARLSGSISNSIVEKINGVKVKGLTHAYELLYPENMPEYVVIELKNGERP
LVFEGKAMETANKRISKTYNIPKNARLDSAIPGRQPGRNTTPAR

Sequences:

>Translated_524_residues
MIHSHTCFQGLCAVLAGTALSHADEPAVSISDFGVDKVMSGPVVSINDQYKGVVKIEMDSLTPDYATPWNTGRYQGGIGT
GFLIGENAFMTNAHVVSNAERIYISMYGDSRKIPARVKFIAHDADLALLEADDPRPFKGIRPFEFSKNLPHLEDEVRVIG
YPIGGNRLSVTRGVVSRIDFTTYAHPRNTEHLTIQVDAAINPGNSGGPVLMGNKVIGVAFQGLNNANNTGYVIPTPVIRH
FLEDIKDGVYDGYVDMGIQAAPILNPAMRKAFGLPDDEKGVLIGKVLKGSSADGVLRNGDLLMKVDGYDVDSSAMIELDG
QKISMKELIERCFKDDRLPLDIIRDGKPMKVEMVMKPSPSRDLLMAEYDKMPRYVVFGGLVFQPIQRNVLAAADISMLDV
ALDIRNYQEDGGCVDHEDMVIITKVLDDEVNARLSGSISNSIVEKINGVKVKGLTHAYELLYPENMPEYVVIELKNGERP
LVFEGKAMETANKRISKTYNIPKNARLDSAIPGRQPGRNTTPAR
>Mature_524_residues
MIHSHTCFQGLCAVLAGTALSHADEPAVSISDFGVDKVMSGPVVSINDQYKGVVKIEMDSLTPDYATPWNTGRYQGGIGT
GFLIGENAFMTNAHVVSNAERIYISMYGDSRKIPARVKFIAHDADLALLEADDPRPFKGIRPFEFSKNLPHLEDEVRVIG
YPIGGNRLSVTRGVVSRIDFTTYAHPRNTEHLTIQVDAAINPGNSGGPVLMGNKVIGVAFQGLNNANNTGYVIPTPVIRH
FLEDIKDGVYDGYVDMGIQAAPILNPAMRKAFGLPDDEKGVLIGKVLKGSSADGVLRNGDLLMKVDGYDVDSSAMIELDG
QKISMKELIERCFKDDRLPLDIIRDGKPMKVEMVMKPSPSRDLLMAEYDKMPRYVVFGGLVFQPIQRNVLAAADISMLDV
ALDIRNYQEDGGCVDHEDMVIITKVLDDEVNARLSGSISNSIVEKINGVKVKGLTHAYELLYPENMPEYVVIELKNGERP
LVFEGKAMETANKRISKTYNIPKNARLDSAIPGRQPGRNTTPAR

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=256, Percent_Identity=28.515625, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI24308541, Length=273, Percent_Identity=27.4725274725275, Blast_Score=66, Evalue=8e-11,
Organism=Escherichia coli, GI1789629, Length=288, Percent_Identity=27.4305555555556, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1786356, Length=290, Percent_Identity=27.2413793103448, Blast_Score=76, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 57465; Mature: 57465

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIHSHTCFQGLCAVLAGTALSHADEPAVSISDFGVDKVMSGPVVSINDQYKGVVKIEMDS
CCCCCHHHHHHHHHHHHHHHCCCCCCCEEEHHCCHHHHCCCCEEEECCCCCEEEEEEECC
LTPDYATPWNTGRYQGGIGTGFLIGENAFMTNAHVVSNAERIYISMYGDSRKIPARVKFI
CCCCCCCCCCCCCCCCCCCCEEEEECCCEEECCEEECCCEEEEEEEECCCCCCCEEEEEE
AHDADLALLEADDPRPFKGIRPFEFSKNLPHLEDEVRVIGYPIGGNRLSVTRGVVSRIDF
EECCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEHHHHHHHHCE
TTYAHPRNTEHLTIQVDAAINPGNSGGPVLMGNKVIGVAFQGLNNANNTGYVIPTPVIRH
EEECCCCCCCEEEEEEEEEECCCCCCCCEEECCEEEEEEEECCCCCCCCCEEECHHHHHH
FLEDIKDGVYDGYVDMGIQAAPILNPAMRKAFGLPDDEKGVLIGKVLKGSSADGVLRNGD
HHHHHHCCCCCCHHHCCCEECCCCCHHHHHHCCCCCCCCCEEEEEEECCCCCCCEEECCC
LLMKVDGYDVDSSAMIELDGQKISMKELIERCFKDDRLPLDIIRDGKPMKVEMVMKPSPS
EEEEECCCCCCCCEEEEECCCEECHHHHHHHHHCCCCCCEEEECCCCCEEEEEEECCCCC
RDLLMAEYDKMPRYVVFGGLVFQPIQRNVLAAADISMLDVALDIRNYQEDGGCVDHEDMV
CCEEHHHHCCCCCEEEECCHHHHHHHCCEEECCCCEEEEEEEEHHCCCCCCCCCCCCCEE
IITKVLDDEVNARLSGSISNSIVEKINGVKVKGLTHAYELLYPENMPEYVVIELKNGERP
EEEEECCCCCCCEECCCHHHHHHHHHCCEEEECCHHEEEEECCCCCCCEEEEEECCCCCC
LVFEGKAMETANKRISKTYNIPKNARLDSAIPGRQPGRNTTPAR
EEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIHSHTCFQGLCAVLAGTALSHADEPAVSISDFGVDKVMSGPVVSINDQYKGVVKIEMDS
CCCCCHHHHHHHHHHHHHHHCCCCCCCEEEHHCCHHHHCCCCEEEECCCCCEEEEEEECC
LTPDYATPWNTGRYQGGIGTGFLIGENAFMTNAHVVSNAERIYISMYGDSRKIPARVKFI
CCCCCCCCCCCCCCCCCCCCEEEEECCCEEECCEEECCCEEEEEEEECCCCCCCEEEEEE
AHDADLALLEADDPRPFKGIRPFEFSKNLPHLEDEVRVIGYPIGGNRLSVTRGVVSRIDF
EECCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEHHHHHHHHCE
TTYAHPRNTEHLTIQVDAAINPGNSGGPVLMGNKVIGVAFQGLNNANNTGYVIPTPVIRH
EEECCCCCCCEEEEEEEEEECCCCCCCCEEECCEEEEEEEECCCCCCCCCEEECHHHHHH
FLEDIKDGVYDGYVDMGIQAAPILNPAMRKAFGLPDDEKGVLIGKVLKGSSADGVLRNGD
HHHHHHCCCCCCHHHCCCEECCCCCHHHHHHCCCCCCCCCEEEEEEECCCCCCCEEECCC
LLMKVDGYDVDSSAMIELDGQKISMKELIERCFKDDRLPLDIIRDGKPMKVEMVMKPSPS
EEEEECCCCCCCCEEEEECCCEECHHHHHHHHHCCCCCCEEEECCCCCEEEEEEECCCCC
RDLLMAEYDKMPRYVVFGGLVFQPIQRNVLAAADISMLDVALDIRNYQEDGGCVDHEDMV
CCEEHHHHCCCCCEEEECCHHHHHHHCCEEECCCCEEEEEEEEHHCCCCCCCCCCCCCEE
IITKVLDDEVNARLSGSISNSIVEKINGVKVKGLTHAYELLYPENMPEYVVIELKNGERP
EEEEECCCCCCCEECCCHHHHHHHHHCCEEEECCHHEEEEECCCCCCCEEEEEECCCCCC
LVFEGKAMETANKRISKTYNIPKNARLDSAIPGRQPGRNTTPAR
EEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]