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The map label for this gene is gltB

Identifier: 187733965

GI number: 187733965

Start: 3309518

End: 3313978

Strand: Reverse

Name: gltB

Synonym: SbBS512_E3558

Alternate gene names: 187733965

Gene position: 3313978-3309518 (Counterclockwise)

Preceding gene: 187731157

Following gene: 187733386

Centisome position: 71.79

GC content: 57.05

Gene sequence:

>4461_bases
ATGTTGTACGATAAATCCCTTGAGAGGGATAACTGTGGTTTCGGCCTGATCGCCCACATAGAAGGCGAACCTAGCCACAA
GGTAGTGCGTACTGCAATACACGCACTGGCCCGCATGCAGCACCGTGGCGCGATTCTCGCCGATGGTAAAACCGGTGACG
GTTGCGGCTTGCTGTTACAAAAACCGGATCGCTTTTTTCGCATCGTTGCGCAGGAGCGCGGCTGGCGTTTAGCAAAAAAC
TACGCTGTCGGGATGCTCTTCCTGAATAAAGATCCTGAACTCGCGGCTGCCGCACGCCGCATCGTTGAAGAAGAGCTGCA
ACGCGAAACCTTGTCGATTGTGGGCTGGCGTGATGTCCCCACTAACGAAGGCGTGCTGGGTGAAATCGCCCTCTCCTCTC
TGCCCCGCATTGAGCAAATTTTCGTTAACGCTCCGGCAGGCTGGCGTCCGCGGGATATGGAGCGCCGTCTGTTTATCGCC
CGCCGCCGCATTGAAAAGCGTCTCGAAGCCGACAAAGACTTCTACGTCTGTAGCCTGTCGAATCTGGTGAACATCTATAA
AGGTCTGTGTATGCCGGCGGATCTGCCGCGCTTTTATCTGGATCTTGCGGACCTGCGTCTGGAATCGGCCATCTGCCTGT
TCCACCAGCGCTTCTCCACTAACACCGTACCGCGCTGGCCGCTGGCGCAGCCGTTCCGCTACCTGGCGCATAACGGTGAA
ATCAACACCATCACCGGTAACCGCCAATGGGCGCGTGCGCGTACCTATAAATTCCAGACGCCGCTTATCCCTGATCTGCA
CGACGCCGCACCGTTCGTCAACGAAACCGGCTCTGACTCCAGTTCGATGGATAACATGCTGGAACTGCTGCTGGCAGGCG
GGATGGATATCATCCGCGCCATGCGTCTGTTAGTGCCACCCGCCTGGCAGAACAACCCGGATATGGACCCGGAACTGCGT
GCCTTCTTTGACTTTAACTCCATGCATATGGAGCCGTGGGATGGCCCGGCGGGCATCGTGATGTCCGACGGTCGTTTTGC
CGCCTGTAACCTCGACCGTAACGGTCTGCGTCCGGCGCGCTACGTCATCACCAAAGATAAGCTCATCACCTGCGCCTCTG
AAGTCGGTATCTGGGATTACCAGCCTGACGAAGTGGTCGAAAAAGGCCGCGTCGGGCCAGGCGAACTGATGGTTATCGAC
ACCCGCAGTGGGCGTATTCTGCACTCGGCAGAAACCGATGACGATCTGAAAAGCCGCCATCCATATAAAGAGTGGATGGA
GAAAAACGTCCGCCGACTGGTACCGTTTGAAGATCTGCCCGATGAAGAAGTGGGTAGCCGCGAACTGGACGACGACACGC
TTGCCAGCTACCAGAAACAGTTTAACTACAGCGCGGAAGAGCTGGACTCCGTAATTCGCGTACTGGGCGAAAACGGTCAG
GAAGCGGTCGGTTCGATGGGCGATGATACCCCATTCGCCGTGCTCTCCAGTCAGCCGCGCATTATTTACGACTACTTCCG
CCAGCAGTTTGCCCAGGTGACTAACCCGCCAATCGACCCGCTGCGTGAAGCGCATGTTATGTCGCTCGCCACCAGTATCG
GTCGTGAAATGAACGTCTTTTGCGAAGCAGAGGGCCAGGCGCACCGTTTAAGCTTTAAATCGCCGATTCTGCTCTACTCC
GATTTCAAACAGCTCACGACGATGAAAGAGGAGCACTACCGCGCAGATACGCTGGATATCACCTTTGACGTCACTAAAAC
CACGCTCGAAGCGACAGTCAAAGAGCTGTGCGACAAAGCCGAAAAAATGGTACGTAGCGGCACCGTGCTGCTGGTGCTCT
CCGACCGGAATATCGCTAAAGATCGCCTGCCGGTTCCAGCCCCGATGGCGGTTGGCGCGATCCAGACCCGTCTGGTCGAT
CAAAGCCTGCGTTGCGATGCCAACATCATCGTCGAAACCGCCAGCGCCCGCGATCCGCACCACTTCGCCGTGTTGCTGGG
CTTCGGCGCGACGGCTATTTATCCATACCTTGCCTATGAAACGCTGGGCCGCCTGGTAGACACCCATGCGATTGCCAAAG
ATTATCGTACCGTGATGCTCAACTACCGTAACGGCATCAACAAAGGCTTGTACAAAATCATGTCCAAAATGGGCATCTCC
ACCATCGCCTCTTACCGCTGCTCGAAACTGTTTGAAGCGGTCGGTCTGCACGATGATGTAGTGGGCCTGTGCTTCCAGGG
GACGGTCAGCCGCATTGGTGGGGCGAGCTTTGAAGACTTCCAGCAGGATCTGCTGAACCTGTCGAAACGTGCCTGGCTGG
CGCGTAAGCCCATCAGCCAGGGCGGCCTGCTGAAATACGTCCACGGCGGCGAATACCACGCTTACAACCCGGACGTGGTG
CGCACGCTGCAACAGGCGGTACAAAGCGGCGAGTACAGCGACTATCAGGAATACGCGAAGCTGGTTAATGAGCGTCCGGC
AACCACGCTGCGCGATCTGCTGGCAATTACGCCGGGTGAAAACGCGGTCAACATTGCTGATGTTGAACCGGCAAGCGAAC
TGTTTAAACGCTTTGATACCGCCGCGATGTCTATCGGCGCGTTAAGCCCGGAAGCCCACGAGGCGCTGGCGGAAGCGATG
AATAGCATCGGCGGTAACTCGAACTCCGGTGAAGGCGGCGAAGACCCGGCGCGCTATGGCACTAACAAAGTGTCGCGCAT
CAAGCAGGTGGCTTCTGGTCGCTTCGGCGTTACTCCGGCGTATCTGGTCAATGCCGACGTCATTCAGATTAAAGTCGCCC
AGGGCGCGAAGCCGGGCGAAGGCGGTCAGTTGCCGGGTGACAAAGTCACTCCTTACATCGCCAAACTGCGCTATTCGGTG
CCCGGAGTGACGCTGATCTCCCCGCCGCCGCACCACGATATCTACTCTATCGAGGACTTAGCGCAGCTCATTTTCGACCT
CAAGCAGGTTAACCCGAAAGCGATGATCTCCGTGAAGCTGGTTTCCGAACCGGGCGTAGGCACCATCGCGACTGGTGTGG
CAAAAGCTTATGCCGATTTAATCACCATCGCAGGCTATGACGGTGGCACCGGCGCAAGCCCGCTGTCGTCAGTGAAATAC
GCAGGTTGCCCGTGGGAGCTGGGGCTTGTTGAAACCCAGCAGGCGCTGGTTGCCAATGGTCTGCGTCATAAGATCCGTTT
GCAGGTCGATGGCGGCCTGAAAACCGGTGTTGATATCATCAAAGCGGCGATTCTCGGCGCAGAAAGCTTCGGCTTCGGCA
CTGGCCCAATGGTCGCGCTCGGCTGTAAATATCTGCGTATTTGCCACCTGAACAACTGCGCAACGGGTGTGGCAACTCAG
GATGACAAACTGCGTAAGAATCACTATCACGGCCTGCCGTTCAAGGTGACGAATTACTTTGAGTTTATCGCCCGTGAAAC
CCGCGAGCTGATGGCACAGCTGGGGGTAACGCGGCTGGTGGATCTGATTGGTCGCACCGACCTGCTGAAAGAGCTGGACG
GTTTCACCGCCAAACAGCAGAAACTGGCGCTGTCGAAGCTGCTGGAGACCGCCGAACCGCATCTAGGTAAGGCACTCTAC
TGCACCGAAAACAACCCGCCGTTTGATAACGGCCTGCTGAACGCGCAGTTGCTGCAACAGGCGAAACCGTTTGTCGATGG
ACGCCAGAGCAAAACCTTCTGGTTCGATATCCGCAATACCGATCGCTCCGTGGGCGCGTCGCTTTCAGGCTATATCGCCC
AGACGCACGGCGATCAGGGGCTGGCAGCCGATCCTATCAAAGCGTACTTCAACGGCACCGCAGGCCAGAGTTTCGGTGTA
TGGAACGCGGGCGGCGTGGAACTGTACCTGACCGGGGATGCCAACGACTATGTCGGTAAAGGCATGGCGGGCGGCTTAAT
CGCCATTCGTCCTCCGGTTGGTTCCGCCTTCCGCAGCCATGAAGCAAGTATTATCGGCAACACCTGCCTGTATGGCGCGA
CCGGTGGTCGTCTGTATGCCGCAGGCCGCGCGGGTGAACGTTTCGGCGTGCGGAACTCCGGTGCTATCACCGTGGTAGAA
GGCATTGGCGACAACGGCTGTGAATATATGACGGGCGGTATTGTCTGTATTCTGGGTAAAACCGGCGTTAACTTCGGTGC
GGGCATGACCGGCGGCTTCGCTTACGTTCTCGATGAAAGCGGTGATTTCCGCAAACGCGTTAACCCGGAACTGGTCGAGG
TCTTAAACGTTGACGATCTGGCGATCCATGAAGAGCATCTGCGCGGTCTTATCACCGAGCATGTTCAGCATACTGGCTCT
CAGCGCGGTGAAGAGATTCTGGCGAACTGGTCAACCTTCGCCACTAAATTTGCGCTGGTTAAACCGAAGTCCAGTGATGT
AAAAGCACTGCTGGGTCACCGTAGTCGTAGCGCAGCAGAGTTGCGCGTGCAGGCGCAGTAA

Upstream 100 bases:

>100_bases
CGCGCGTATGACACGCAACCCCCGTCGCCACGCTCTTTCTGTGCCCGTGCGCAGCGGTTCGGAAGTGGGGTTCCCGCAGA
GCCTGGGGGAGGTTCACGAT

Downstream 100 bases:

>100_bases
GGGGTAGCAACAATGAGTCAGAATGTTTATCAATTTATCGACCTGCAGCGCGTTGATCCGCCTAAGAAACCGCTGAAGAT
CCGCAAAATTGAGTTTGTTG

Product: glutamate synthase subunit alpha

Products: NA

Alternate protein names: Glutamate synthase subunit alpha; GLTS alpha chain; NADPH-GOGAT [H]

Number of amino acids: Translated: 1486; Mature: 1486

Protein sequence:

>1486_residues
MLYDKSLERDNCGFGLIAHIEGEPSHKVVRTAIHALARMQHRGAILADGKTGDGCGLLLQKPDRFFRIVAQERGWRLAKN
YAVGMLFLNKDPELAAAARRIVEEELQRETLSIVGWRDVPTNEGVLGEIALSSLPRIEQIFVNAPAGWRPRDMERRLFIA
RRRIEKRLEADKDFYVCSLSNLVNIYKGLCMPADLPRFYLDLADLRLESAICLFHQRFSTNTVPRWPLAQPFRYLAHNGE
INTITGNRQWARARTYKFQTPLIPDLHDAAPFVNETGSDSSSMDNMLELLLAGGMDIIRAMRLLVPPAWQNNPDMDPELR
AFFDFNSMHMEPWDGPAGIVMSDGRFAACNLDRNGLRPARYVITKDKLITCASEVGIWDYQPDEVVEKGRVGPGELMVID
TRSGRILHSAETDDDLKSRHPYKEWMEKNVRRLVPFEDLPDEEVGSRELDDDTLASYQKQFNYSAEELDSVIRVLGENGQ
EAVGSMGDDTPFAVLSSQPRIIYDYFRQQFAQVTNPPIDPLREAHVMSLATSIGREMNVFCEAEGQAHRLSFKSPILLYS
DFKQLTTMKEEHYRADTLDITFDVTKTTLEATVKELCDKAEKMVRSGTVLLVLSDRNIAKDRLPVPAPMAVGAIQTRLVD
QSLRCDANIIVETASARDPHHFAVLLGFGATAIYPYLAYETLGRLVDTHAIAKDYRTVMLNYRNGINKGLYKIMSKMGIS
TIASYRCSKLFEAVGLHDDVVGLCFQGTVSRIGGASFEDFQQDLLNLSKRAWLARKPISQGGLLKYVHGGEYHAYNPDVV
RTLQQAVQSGEYSDYQEYAKLVNERPATTLRDLLAITPGENAVNIADVEPASELFKRFDTAAMSIGALSPEAHEALAEAM
NSIGGNSNSGEGGEDPARYGTNKVSRIKQVASGRFGVTPAYLVNADVIQIKVAQGAKPGEGGQLPGDKVTPYIAKLRYSV
PGVTLISPPPHHDIYSIEDLAQLIFDLKQVNPKAMISVKLVSEPGVGTIATGVAKAYADLITIAGYDGGTGASPLSSVKY
AGCPWELGLVETQQALVANGLRHKIRLQVDGGLKTGVDIIKAAILGAESFGFGTGPMVALGCKYLRICHLNNCATGVATQ
DDKLRKNHYHGLPFKVTNYFEFIARETRELMAQLGVTRLVDLIGRTDLLKELDGFTAKQQKLALSKLLETAEPHLGKALY
CTENNPPFDNGLLNAQLLQQAKPFVDGRQSKTFWFDIRNTDRSVGASLSGYIAQTHGDQGLAADPIKAYFNGTAGQSFGV
WNAGGVELYLTGDANDYVGKGMAGGLIAIRPPVGSAFRSHEASIIGNTCLYGATGGRLYAAGRAGERFGVRNSGAITVVE
GIGDNGCEYMTGGIVCILGKTGVNFGAGMTGGFAYVLDESGDFRKRVNPELVEVLNVDDLAIHEEHLRGLITEHVQHTGS
QRGEEILANWSTFATKFALVKPKSSDVKALLGHRSRSAAELRVQAQ

Sequences:

>Translated_1486_residues
MLYDKSLERDNCGFGLIAHIEGEPSHKVVRTAIHALARMQHRGAILADGKTGDGCGLLLQKPDRFFRIVAQERGWRLAKN
YAVGMLFLNKDPELAAAARRIVEEELQRETLSIVGWRDVPTNEGVLGEIALSSLPRIEQIFVNAPAGWRPRDMERRLFIA
RRRIEKRLEADKDFYVCSLSNLVNIYKGLCMPADLPRFYLDLADLRLESAICLFHQRFSTNTVPRWPLAQPFRYLAHNGE
INTITGNRQWARARTYKFQTPLIPDLHDAAPFVNETGSDSSSMDNMLELLLAGGMDIIRAMRLLVPPAWQNNPDMDPELR
AFFDFNSMHMEPWDGPAGIVMSDGRFAACNLDRNGLRPARYVITKDKLITCASEVGIWDYQPDEVVEKGRVGPGELMVID
TRSGRILHSAETDDDLKSRHPYKEWMEKNVRRLVPFEDLPDEEVGSRELDDDTLASYQKQFNYSAEELDSVIRVLGENGQ
EAVGSMGDDTPFAVLSSQPRIIYDYFRQQFAQVTNPPIDPLREAHVMSLATSIGREMNVFCEAEGQAHRLSFKSPILLYS
DFKQLTTMKEEHYRADTLDITFDVTKTTLEATVKELCDKAEKMVRSGTVLLVLSDRNIAKDRLPVPAPMAVGAIQTRLVD
QSLRCDANIIVETASARDPHHFAVLLGFGATAIYPYLAYETLGRLVDTHAIAKDYRTVMLNYRNGINKGLYKIMSKMGIS
TIASYRCSKLFEAVGLHDDVVGLCFQGTVSRIGGASFEDFQQDLLNLSKRAWLARKPISQGGLLKYVHGGEYHAYNPDVV
RTLQQAVQSGEYSDYQEYAKLVNERPATTLRDLLAITPGENAVNIADVEPASELFKRFDTAAMSIGALSPEAHEALAEAM
NSIGGNSNSGEGGEDPARYGTNKVSRIKQVASGRFGVTPAYLVNADVIQIKVAQGAKPGEGGQLPGDKVTPYIAKLRYSV
PGVTLISPPPHHDIYSIEDLAQLIFDLKQVNPKAMISVKLVSEPGVGTIATGVAKAYADLITIAGYDGGTGASPLSSVKY
AGCPWELGLVETQQALVANGLRHKIRLQVDGGLKTGVDIIKAAILGAESFGFGTGPMVALGCKYLRICHLNNCATGVATQ
DDKLRKNHYHGLPFKVTNYFEFIARETRELMAQLGVTRLVDLIGRTDLLKELDGFTAKQQKLALSKLLETAEPHLGKALY
CTENNPPFDNGLLNAQLLQQAKPFVDGRQSKTFWFDIRNTDRSVGASLSGYIAQTHGDQGLAADPIKAYFNGTAGQSFGV
WNAGGVELYLTGDANDYVGKGMAGGLIAIRPPVGSAFRSHEASIIGNTCLYGATGGRLYAAGRAGERFGVRNSGAITVVE
GIGDNGCEYMTGGIVCILGKTGVNFGAGMTGGFAYVLDESGDFRKRVNPELVEVLNVDDLAIHEEHLRGLITEHVQHTGS
QRGEEILANWSTFATKFALVKPKSSDVKALLGHRSRSAAELRVQAQ
>Mature_1486_residues
MLYDKSLERDNCGFGLIAHIEGEPSHKVVRTAIHALARMQHRGAILADGKTGDGCGLLLQKPDRFFRIVAQERGWRLAKN
YAVGMLFLNKDPELAAAARRIVEEELQRETLSIVGWRDVPTNEGVLGEIALSSLPRIEQIFVNAPAGWRPRDMERRLFIA
RRRIEKRLEADKDFYVCSLSNLVNIYKGLCMPADLPRFYLDLADLRLESAICLFHQRFSTNTVPRWPLAQPFRYLAHNGE
INTITGNRQWARARTYKFQTPLIPDLHDAAPFVNETGSDSSSMDNMLELLLAGGMDIIRAMRLLVPPAWQNNPDMDPELR
AFFDFNSMHMEPWDGPAGIVMSDGRFAACNLDRNGLRPARYVITKDKLITCASEVGIWDYQPDEVVEKGRVGPGELMVID
TRSGRILHSAETDDDLKSRHPYKEWMEKNVRRLVPFEDLPDEEVGSRELDDDTLASYQKQFNYSAEELDSVIRVLGENGQ
EAVGSMGDDTPFAVLSSQPRIIYDYFRQQFAQVTNPPIDPLREAHVMSLATSIGREMNVFCEAEGQAHRLSFKSPILLYS
DFKQLTTMKEEHYRADTLDITFDVTKTTLEATVKELCDKAEKMVRSGTVLLVLSDRNIAKDRLPVPAPMAVGAIQTRLVD
QSLRCDANIIVETASARDPHHFAVLLGFGATAIYPYLAYETLGRLVDTHAIAKDYRTVMLNYRNGINKGLYKIMSKMGIS
TIASYRCSKLFEAVGLHDDVVGLCFQGTVSRIGGASFEDFQQDLLNLSKRAWLARKPISQGGLLKYVHGGEYHAYNPDVV
RTLQQAVQSGEYSDYQEYAKLVNERPATTLRDLLAITPGENAVNIADVEPASELFKRFDTAAMSIGALSPEAHEALAEAM
NSIGGNSNSGEGGEDPARYGTNKVSRIKQVASGRFGVTPAYLVNADVIQIKVAQGAKPGEGGQLPGDKVTPYIAKLRYSV
PGVTLISPPPHHDIYSIEDLAQLIFDLKQVNPKAMISVKLVSEPGVGTIATGVAKAYADLITIAGYDGGTGASPLSSVKY
AGCPWELGLVETQQALVANGLRHKIRLQVDGGLKTGVDIIKAAILGAESFGFGTGPMVALGCKYLRICHLNNCATGVATQ
DDKLRKNHYHGLPFKVTNYFEFIARETRELMAQLGVTRLVDLIGRTDLLKELDGFTAKQQKLALSKLLETAEPHLGKALY
CTENNPPFDNGLLNAQLLQQAKPFVDGRQSKTFWFDIRNTDRSVGASLSGYIAQTHGDQGLAADPIKAYFNGTAGQSFGV
WNAGGVELYLTGDANDYVGKGMAGGLIAIRPPVGSAFRSHEASIIGNTCLYGATGGRLYAAGRAGERFGVRNSGAITVVE
GIGDNGCEYMTGGIVCILGKTGVNFGAGMTGGFAYVLDESGDFRKRVNPELVEVLNVDDLAIHEEHLRGLITEHVQHTGS
QRGEEILANWSTFATKFALVKPKSSDVKALLGHRSRSAAELRVQAQ

Specific function: NITROGEN METABOLISM, GLUTAMATE BIOSYNTHESIS. THE CATALYZED REACTION BRINGS TOGETHER THE NITROGEN AND CARBON METABOLISM. [C]

COG id: COG0069

COG function: function code E; Glutamate synthase domain 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI308199519, Length=1486, Percent_Identity=99.5962314939435, Blast_Score=3061, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17570289, Length=1534, Percent_Identity=41.9165580182529, Blast_Score=1086, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6320030, Length=1530, Percent_Identity=41.9607843137255, Blast_Score=1140, Evalue=0.0,
Organism=Drosophila melanogaster, GI28574881, Length=1498, Percent_Identity=43.524699599466, Blast_Score=1146, Evalue=0.0,
Organism=Drosophila melanogaster, GI24665539, Length=1498, Percent_Identity=43.524699599466, Blast_Score=1146, Evalue=0.0,
Organism=Drosophila melanogaster, GI24665547, Length=369, Percent_Identity=44.9864498644986, Blast_Score=283, Evalue=8e-76,
Organism=Drosophila melanogaster, GI24665543, Length=369, Percent_Identity=44.9864498644986, Blast_Score=283, Evalue=8e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR002932
- InterPro:   IPR006982
- InterPro:   IPR002489 [H]

Pfam domain/function: PF00310 GATase_2; PF04898 Glu_syn_central; PF01645 Glu_synthase; PF01493 GXGXG [H]

EC number: =1.4.1.13 [H]

Molecular weight: Translated: 163314; Mature: 163314

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYDKSLERDNCGFGLIAHIEGEPSHKVVRTAIHALARMQHRGAILADGKTGDGCGLLLQ
CCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCEEEEC
KPDRFFRIVAQERGWRLAKNYAVGMLFLNKDPELAAAARRIVEEELQRETLSIVGWRDVP
CCCHHHHHHHHHCCCEEECCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHEEECCCCC
TNEGVLGEIALSSLPRIEQIFVNAPAGWRPRDMERRLFIARRRIEKRLEADKDFYVCSLS
CCCCCCHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEHH
NLVNIYKGLCMPADLPRFYLDLADLRLESAICLFHQRFSTNTVPRWPLAQPFRYLAHNGE
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCC
INTITGNRQWARARTYKFQTPLIPDLHDAAPFVNETGSDSSSMDNMLELLLAGGMDIIRA
EEEEECCCCCHHHHEEEECCCCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHH
MRLLVPPAWQNNPDMDPELRAFFDFNSMHMEPWDGPAGIVMSDGRFAACNLDRNGLRPAR
HHHHCCCCCCCCCCCCHHHHEEEECCCCCCCCCCCCCCEEEECCEEEEECCCCCCCCCCC
YVITKDKLITCASEVGIWDYQPDEVVEKGRVGPGELMVIDTRSGRILHSAETDDDLKSRH
EEEECCHHHHHHHHCCCCCCCHHHHHHCCCCCCCCEEEEECCCCEEEECCCCCHHHHHCC
PYKEWMEKNVRRLVPFEDLPDEEVGSRELDDDTLASYQKQFNYSAEELDSVIRVLGENGQ
CHHHHHHHHHHHCCCCCCCCCHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCH
EAVGSMGDDTPFAVLSSQPRIIYDYFRQQFAQVTNPPIDPLREAHVMSLATSIGREMNVF
HHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEE
CEAEGQAHRLSFKSPILLYSDFKQLTTMKEEHYRADTLDITFDVTKTTLEATVKELCDKA
EECCCCEEEEECCCCEEEHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHHHH
EKMVRSGTVLLVLSDRNIAKDRLPVPAPMAVGAIQTRLVDQSLRCDANIIVETASARDPH
HHHHHCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCC
HFAVLLGFGATAIYPYLAYETLGRLVDTHAIAKDYRTVMLNYRNGINKGLYKIMSKMGIS
EEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHCCCHHHHHHHHHHHCHH
TIASYRCSKLFEAVGLHDDVVGLCFQGTVSRIGGASFEDFQQDLLNLSKRAWLARKPISQ
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCC
GGLLKYVHGGEYHAYNPDVVRTLQQAVQSGEYSDYQEYAKLVNERPATTLRDLLAITPGE
CCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHEECCCC
NAVNIADVEPASELFKRFDTAAMSIGALSPEAHEALAEAMNSIGGNSNSGEGGEDPARYG
CCEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHC
TNKVSRIKQVASGRFGVTPAYLVNADVIQIKVAQGAKPGEGGQLPGDKVTPYIAKLRYSV
CHHHHHHHHHHCCCCCCCCCEEECCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHEECC
PGVTLISPPPHHDIYSIEDLAQLIFDLKQVNPKAMISVKLVSEPGVGTIATGVAKAYADL
CCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHH
ITIAGYDGGTGASPLSSVKYAGCPWELGLVETQQALVANGLRHKIRLQVDGGLKTGVDII
HEEECCCCCCCCCCHHHCCCCCCCEECCHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHH
KAAILGAESFGFGTGPMVALGCKYLRICHLNNCATGVATQDDKLRKNHYHGLPFKVTNYF
HHHHHCCCCCCCCCCCHHHHHHHHHEEEECCCCCCCCCCCCHHHHHCCCCCCCEEHHHHH
EFIARETRELMAQLGVTRLVDLIGRTDLLKELDGFTAKQQKLALSKLLETAEPHLGKALY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCEEE
CTENNPPFDNGLLNAQLLQQAKPFVDGRQSKTFWFDIRNTDRSVGASLSGYIAQTHGDQG
ECCCCCCCCCCCCCHHHHHHCCCCCCCCCCCEEEEEECCCCHHHCCCHHCEEEECCCCCC
LAADPIKAYFNGTAGQSFGVWNAGGVELYLTGDANDYVGKGMAGGLIAIRPPVGSAFRSH
CCCCCHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCHHCCCCCCCEEEEECCCCHHHHCC
EASIIGNTCLYGATGGRLYAAGRAGERFGVRNSGAITVVEGIGDNGCEYMTGGIVCILGK
CCCEECCEEEECCCCCEEEECCCCCCCCCCCCCCCEEEEECCCCCCCCEECCCEEEEEEC
TGVNFGAGMTGGFAYVLDESGDFRKRVNPELVEVLNVDDLAIHEEHLRGLITEHVQHTGS
CCCCCCCCCCCCEEEEECCCCCHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
QRGEEILANWSTFATKFALVKPKSSDVKALLGHRSRSAAELRVQAQ
HHHHHHHHHHHHHHHEEEEECCCCCCHHHHHCCCCCCCEEEEEECC
>Mature Secondary Structure
MLYDKSLERDNCGFGLIAHIEGEPSHKVVRTAIHALARMQHRGAILADGKTGDGCGLLLQ
CCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCEEEEC
KPDRFFRIVAQERGWRLAKNYAVGMLFLNKDPELAAAARRIVEEELQRETLSIVGWRDVP
CCCHHHHHHHHHCCCEEECCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHEEECCCCC
TNEGVLGEIALSSLPRIEQIFVNAPAGWRPRDMERRLFIARRRIEKRLEADKDFYVCSLS
CCCCCCHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEHH
NLVNIYKGLCMPADLPRFYLDLADLRLESAICLFHQRFSTNTVPRWPLAQPFRYLAHNGE
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCC
INTITGNRQWARARTYKFQTPLIPDLHDAAPFVNETGSDSSSMDNMLELLLAGGMDIIRA
EEEEECCCCCHHHHEEEECCCCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHH
MRLLVPPAWQNNPDMDPELRAFFDFNSMHMEPWDGPAGIVMSDGRFAACNLDRNGLRPAR
HHHHCCCCCCCCCCCCHHHHEEEECCCCCCCCCCCCCCEEEECCEEEEECCCCCCCCCCC
YVITKDKLITCASEVGIWDYQPDEVVEKGRVGPGELMVIDTRSGRILHSAETDDDLKSRH
EEEECCHHHHHHHHCCCCCCCHHHHHHCCCCCCCCEEEEECCCCEEEECCCCCHHHHHCC
PYKEWMEKNVRRLVPFEDLPDEEVGSRELDDDTLASYQKQFNYSAEELDSVIRVLGENGQ
CHHHHHHHHHHHCCCCCCCCCHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCH
EAVGSMGDDTPFAVLSSQPRIIYDYFRQQFAQVTNPPIDPLREAHVMSLATSIGREMNVF
HHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEE
CEAEGQAHRLSFKSPILLYSDFKQLTTMKEEHYRADTLDITFDVTKTTLEATVKELCDKA
EECCCCEEEEECCCCEEEHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHHHH
EKMVRSGTVLLVLSDRNIAKDRLPVPAPMAVGAIQTRLVDQSLRCDANIIVETASARDPH
HHHHHCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCC
HFAVLLGFGATAIYPYLAYETLGRLVDTHAIAKDYRTVMLNYRNGINKGLYKIMSKMGIS
EEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHCCCHHHHHHHHHHHCHH
TIASYRCSKLFEAVGLHDDVVGLCFQGTVSRIGGASFEDFQQDLLNLSKRAWLARKPISQ
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCC
GGLLKYVHGGEYHAYNPDVVRTLQQAVQSGEYSDYQEYAKLVNERPATTLRDLLAITPGE
CCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHEECCCC
NAVNIADVEPASELFKRFDTAAMSIGALSPEAHEALAEAMNSIGGNSNSGEGGEDPARYG
CCEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHC
TNKVSRIKQVASGRFGVTPAYLVNADVIQIKVAQGAKPGEGGQLPGDKVTPYIAKLRYSV
CHHHHHHHHHHCCCCCCCCCEEECCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHEECC
PGVTLISPPPHHDIYSIEDLAQLIFDLKQVNPKAMISVKLVSEPGVGTIATGVAKAYADL
CCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHH
ITIAGYDGGTGASPLSSVKYAGCPWELGLVETQQALVANGLRHKIRLQVDGGLKTGVDII
HEEECCCCCCCCCCHHHCCCCCCCEECCHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHH
KAAILGAESFGFGTGPMVALGCKYLRICHLNNCATGVATQDDKLRKNHYHGLPFKVTNYF
HHHHHCCCCCCCCCCCHHHHHHHHHEEEECCCCCCCCCCCCHHHHHCCCCCCCEEHHHHH
EFIARETRELMAQLGVTRLVDLIGRTDLLKELDGFTAKQQKLALSKLLETAEPHLGKALY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCEEE
CTENNPPFDNGLLNAQLLQQAKPFVDGRQSKTFWFDIRNTDRSVGASLSGYIAQTHGDQG
ECCCCCCCCCCCCCHHHHHHCCCCCCCCCCCEEEEEECCCCHHHCCCHHCEEEECCCCCC
LAADPIKAYFNGTAGQSFGVWNAGGVELYLTGDANDYVGKGMAGGLIAIRPPVGSAFRSH
CCCCCHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCHHCCCCCCCEEEEECCCCHHHHCC
EASIIGNTCLYGATGGRLYAAGRAGERFGVRNSGAITVVEGIGDNGCEYMTGGIVCILGK
CCCEECCEEEECCCCCEEEECCCCCCCCCCCCCCCEEEEECCCCCCCCEECCCEEEEEEC
TGVNFGAGMTGGFAYVLDESGDFRKRVNPELVEVLNVDDLAIHEEHLRGLITEHVQHTGS
CCCCCCCCCCCCEEEEECCCCCHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
QRGEEILANWSTFATKFALVKPKSSDVKALLGHRSRSAAELRVQAQ
HHHHHHHHHHHHHHHEEEEECCCCCCHHHHHCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3326786; 9278503; 1673677; 2643092 [H]