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The map label for this gene is tldD

Identifier: 187730693

GI number: 187730693

Start: 3047693

End: 3049138

Strand: Reverse

Name: tldD

Synonym: SbBS512_E3276

Alternate gene names: 187730693

Gene position: 3049138-3047693 (Counterclockwise)

Preceding gene: 187731278

Following gene: 187732389

Centisome position: 66.06

GC content: 54.98

Gene sequence:

>1446_bases
ATGACTCTTAACCTGGTAAGTGAACAATTGCTAGCGGCGAACGGCCTGAAACATCAGGACTTGTTCGCGATCCTCGGTCA
ACTGGCCGAACGTCGCCTTGATTATGGCGATCTCTATTTTCAGTCGAGCTATCACGAATCCTGGGTTTTAGAAGACCGCA
TTATTAAAGATGGTTCTTACAACATCGATCAGGGCGTTGGCGTGCGTGCAATCAGCGGTGAAAAAACCGGATTTGCTTAC
GCTGACCAAATCAGCCTGCTGGCGCTGGAACAGAGTGCGCAAGCGGCGCGCACCATCGTCCGTGATAGTGGTGATGGCAA
AGTACAGACGCTGGGCGCGGTAGGGCATAGCCCGTTGTATACCTCGGTAGATCCGCTGCAAAGCATGAGCCGTGAAGAGA
AGCTGGATATCCTGCGTCGCGTCGATAAGGTTGCTCGCGAAGCGGACAAGCGCGTACAGGAAGTGACTGCCAGCCTCAGT
GGTGTCTATGAATTAATTCTGGTTGCGGCCACCGACGGCACGCTAGCGGCGGATGTCCGTCCGCTGGTGCGTCTTTCCGT
GAGCGTTCTGGTCGAAGAAGATGGCAAACGCGAACGCGGTGCCGGTGGCGGTGGCGGTCGTTTTGGTTATGAGTTCTTCC
TTGCCGATCTTGACGGCGAAGTCCGTGCGGATGCATGGGCAAAAGAAGCAGTGCGTATGGCGCTGGTCAATCTTTCTGCC
GTTGCTGCACCAGCGGGCACCATGCCGGTAGTACTTGGCGCAGGTTGGCCGGGCGTGCTGTTGCATGAAGCGGTAGGTCA
CGGTCTGGAAGGCGACTTCAACCGCCGCGGCACTTCAGTATTTAGTGGGCAGGTCGGGGAGCTGGTGGCTTCAGAACTGT
GTACCGTGGTTGATGACGGCACGATGGTCGATCGCCGTGGTTCGGTGGCGATTGATGACGAAGGTACGCCAGGCCAGTAC
AACGTGCTGATTGAGAACGGCATTCTGAAAGGCTACATGCAGGATAAACTCAACGCGCGTTTGATGGGGATGACGCCGAC
TGGCAACGGTCGCCGTGAATCCTACGCCCATCTGCCCATGCCGCGTATGACCAACACCTATATGCTGCCGGGTAAATCGA
CCCCGCAGGAAATTATTGAATCCGTTGAGTACGGTATCTATGCACCGAACTTTGGTGGCGGTCAGGTGGATATCACCTCC
GGCAAATTCGTTTTCTCCACTTCAGAAGCATATCTGATTGAAAACGGTAAAGTAACGAAGCCGGTGAGAGGCGCAACGTT
GATTGGTTCCGGTATCGAAACCATGCAGCAGATTTCGATGGTTGGCAACGACCTGAAACTGGATAACGGCGTAGGTGTCT
GCGGTAAAGAAGGGCAAAGTTTGCCGGTTGGCGTGGGCCAGCCAACGCTGAAAGTTGATAACCTGACTGTTGGCGGTACT
GCGTAA

Upstream 100 bases:

>100_bases
AACGAGCCAGAACATAACCGTAGGTCGGATAGGGCGTTCACGCCGCATCCGGCAGCCGTAAAAAATCCTCTACTGCAGTA
ACTAACGAGTAGCAAAAACG

Downstream 100 bases:

>100_bases
TAATTTCATTATTTTCAGAAGGATAATTAATCTTTCTACATGCACGAACGGTCCCCTCGCTCCTCTGGGGTTAGGGTGAG
GGGAACCCGTTGGCACAGGT

Product: protease TldD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 481; Mature: 480

Protein sequence:

>481_residues
MTLNLVSEQLLAANGLKHQDLFAILGQLAERRLDYGDLYFQSSYHESWVLEDRIIKDGSYNIDQGVGVRAISGEKTGFAY
ADQISLLALEQSAQAARTIVRDSGDGKVQTLGAVGHSPLYTSVDPLQSMSREEKLDILRRVDKVAREADKRVQEVTASLS
GVYELILVAATDGTLAADVRPLVRLSVSVLVEEDGKRERGAGGGGGRFGYEFFLADLDGEVRADAWAKEAVRMALVNLSA
VAAPAGTMPVVLGAGWPGVLLHEAVGHGLEGDFNRRGTSVFSGQVGELVASELCTVVDDGTMVDRRGSVAIDDEGTPGQY
NVLIENGILKGYMQDKLNARLMGMTPTGNGRRESYAHLPMPRMTNTYMLPGKSTPQEIIESVEYGIYAPNFGGGQVDITS
GKFVFSTSEAYLIENGKVTKPVRGATLIGSGIETMQQISMVGNDLKLDNGVGVCGKEGQSLPVGVGQPTLKVDNLTVGGT
A

Sequences:

>Translated_481_residues
MTLNLVSEQLLAANGLKHQDLFAILGQLAERRLDYGDLYFQSSYHESWVLEDRIIKDGSYNIDQGVGVRAISGEKTGFAY
ADQISLLALEQSAQAARTIVRDSGDGKVQTLGAVGHSPLYTSVDPLQSMSREEKLDILRRVDKVAREADKRVQEVTASLS
GVYELILVAATDGTLAADVRPLVRLSVSVLVEEDGKRERGAGGGGGRFGYEFFLADLDGEVRADAWAKEAVRMALVNLSA
VAAPAGTMPVVLGAGWPGVLLHEAVGHGLEGDFNRRGTSVFSGQVGELVASELCTVVDDGTMVDRRGSVAIDDEGTPGQY
NVLIENGILKGYMQDKLNARLMGMTPTGNGRRESYAHLPMPRMTNTYMLPGKSTPQEIIESVEYGIYAPNFGGGQVDITS
GKFVFSTSEAYLIENGKVTKPVRGATLIGSGIETMQQISMVGNDLKLDNGVGVCGKEGQSLPVGVGQPTLKVDNLTVGGT
A
>Mature_480_residues
TLNLVSEQLLAANGLKHQDLFAILGQLAERRLDYGDLYFQSSYHESWVLEDRIIKDGSYNIDQGVGVRAISGEKTGFAYA
DQISLLALEQSAQAARTIVRDSGDGKVQTLGAVGHSPLYTSVDPLQSMSREEKLDILRRVDKVAREADKRVQEVTASLSG
VYELILVAATDGTLAADVRPLVRLSVSVLVEEDGKRERGAGGGGGRFGYEFFLADLDGEVRADAWAKEAVRMALVNLSAV
AAPAGTMPVVLGAGWPGVLLHEAVGHGLEGDFNRRGTSVFSGQVGELVASELCTVVDDGTMVDRRGSVAIDDEGTPGQYN
VLIENGILKGYMQDKLNARLMGMTPTGNGRRESYAHLPMPRMTNTYMLPGKSTPQEIIESVEYGIYAPNFGGGQVDITSG
KFVFSTSEAYLIENGKVTKPVRGATLIGSGIETMQQISMVGNDLKLDNGVGVCGKEGQSLPVGVGQPTLKVDNLTVGGTA

Specific function: Suppresses the inhibitory activity of the carbon storage regulator (CsrA) [H]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=481, Percent_Identity=99.1683991683992, Blast_Score=965, Evalue=0.0,
Organism=Escherichia coli, GI1790682, Length=408, Percent_Identity=20.5882352941176, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 51305; Mature: 51174

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLNLVSEQLLAANGLKHQDLFAILGQLAERRLDYGDLYFQSSYHESWVLEDRIIKDGSY
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEHHHEECCCCC
NIDQGVGVRAISGEKTGFAYADQISLLALEQSAQAARTIVRDSGDGKVQTLGAVGHSPLY
CCCCCCCEEEECCCCCCCEECCCEEEEEEHHHHHHHHHHHHCCCCCCEEEEECCCCCCCC
TSVDPLQSMSREEKLDILRRVDKVAREADKRVQEVTASLSGVYELILVAATDGTLAADVR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCHHHHH
PLVRLSVSVLVEEDGKRERGAGGGGGRFGYEFFLADLDGEVRADAWAKEAVRMALVNLSA
HHHHHEEEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
VAAPAGTMPVVLGAGWPGVLLHEAVGHGLEGDFNRRGTSVFSGQVGELVASELCTVVDDG
HCCCCCCCCEEEECCCCHHHHHHHHCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHCCC
TMVDRRGSVAIDDEGTPGQYNVLIENGILKGYMQDKLNARLMGMTPTGNGRRESYAHLPM
EEEECCCCEEECCCCCCCEEEEEEECCHHHHHHHHCCCCEEEEECCCCCCCCCCEECCCC
PRMTNTYMLPGKSTPQEIIESVEYGIYAPNFGGGQVDITSGKFVFSTSEAYLIENGKVTK
CCCCCEEECCCCCCHHHHHHHHHCCEECCCCCCCEEEEECCEEEEECCCEEEEECCCCCC
PVRGATLIGSGIETMQQISMVGNDLKLDNGVGVCGKEGQSLPVGVGQPTLKVDNLTVGGT
CCCCCEEECCHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCCEEECCEECCCC
A
C
>Mature Secondary Structure 
TLNLVSEQLLAANGLKHQDLFAILGQLAERRLDYGDLYFQSSYHESWVLEDRIIKDGSY
CHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEHHHEECCCCC
NIDQGVGVRAISGEKTGFAYADQISLLALEQSAQAARTIVRDSGDGKVQTLGAVGHSPLY
CCCCCCCEEEECCCCCCCEECCCEEEEEEHHHHHHHHHHHHCCCCCCEEEEECCCCCCCC
TSVDPLQSMSREEKLDILRRVDKVAREADKRVQEVTASLSGVYELILVAATDGTLAADVR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCHHHHH
PLVRLSVSVLVEEDGKRERGAGGGGGRFGYEFFLADLDGEVRADAWAKEAVRMALVNLSA
HHHHHEEEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
VAAPAGTMPVVLGAGWPGVLLHEAVGHGLEGDFNRRGTSVFSGQVGELVASELCTVVDDG
HCCCCCCCCEEEECCCCHHHHHHHHCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHCCC
TMVDRRGSVAIDDEGTPGQYNVLIENGILKGYMQDKLNARLMGMTPTGNGRRESYAHLPM
EEEECCCCEEECCCCCCCEEEEEEECCHHHHHHHHCCCCEEEEECCCCCCCCCCEECCCC
PRMTNTYMLPGKSTPQEIIESVEYGIYAPNFGGGQVDITSGKFVFSTSEAYLIENGKVTK
CCCCCEEECCCCCCHHHHHHHHHCCEECCCCCCCEEEEECCEEEEECCCEEEEECCCCCC
PVRGATLIGSGIETMQQISMVGNDLKLDNGVGVCGKEGQSLPVGVGQPTLKVDNLTVGGT
CCCCCEEECCHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCCEEECCEECCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]