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The map label for this gene is cobU [H]

Identifier: 187730237

GI number: 187730237

Start: 888628

End: 889062

Strand: Direct

Name: cobU [H]

Synonym: SbBS512_E0963

Alternate gene names: 187730237

Gene position: 888628-889062 (Clockwise)

Preceding gene: 187730977

Following gene: 187733522

Centisome position: 19.25

GC content: 50.57

Gene sequence:

>435_bases
ATGATGATTTTGGTGACGGGGGGCGCACGGAGCGGGAAGAGTCGCCACGCAGAGGCGCTTATTGGGGACTCTTCACAGGT
TCTGTATATCGCTACCTCGCAAATCCTTGATGATGAGATGGCTGCACGGATAGAACATCATCGGCAAGGCCGCCCGGAGC
ACTGGCGCACAGTGGAGCGCTGGCAACATCTTGATGAATTAATTCATGCAGACATTAACCCGAATGAGGTTGTGTTGCTG
GAATGCGTTACCACAATGGTGACTAATCTGTTGTTTGATTATGGCGGCGATAAAGACCCTGATGAATGGGATTATCAGGC
GATGGAACAGGCGATTAATGCTGAGATTCAGTCGTTGATTGCTGCCTGCCAACGTTGCCCCGCAAAGGTTGTATTAGTGA
CTAACGAAGTGGGGGTAATGCTGCCAACTTACTGA

Upstream 100 bases:

>100_bases
CGCGCAGTATTAATCGCGTAAATGTTTTGCGGTCAGCAACGGTGGGGGATCCATTGTTCTGTTCAATGAATACCATCATA
CATTTGAATCAGGAGTCGGT

Downstream 100 bases:

>100_bases
TTTAGTGTATGATGGTGATTTTAAGGTGCTTGCGTGGCTTCCATTTCCATCAGATGTCCTTCCTGCTCCGCTACTGAAGG
CGTGGTGCGTAACGGCAAAA

Product: bifunctional adenosylcobalamin biosynthesis protein CobU

Products: NA

Alternate protein names: Adenosylcobinamide kinase; Adenosylcobinamide-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 144; Mature: 144

Protein sequence:

>144_residues
MMILVTGGARSGKSRHAEALIGDSSQVLYIATSQILDDEMAARIEHHRQGRPEHWRTVERWQHLDELIHADINPNEVVLL
ECVTTMVTNLLFDYGGDKDPDEWDYQAMEQAINAEIQSLIAACQRCPAKVVLVTNEVGVMLPTY

Sequences:

>Translated_144_residues
MMILVTGGARSGKSRHAEALIGDSSQVLYIATSQILDDEMAARIEHHRQGRPEHWRTVERWQHLDELIHADINPNEVVLL
ECVTTMVTNLLFDYGGDKDPDEWDYQAMEQAINAEIQSLIAACQRCPAKVVLVTNEVGVMLPTY
>Mature_144_residues
MMILVTGGARSGKSRHAEALIGDSSQVLYIATSQILDDEMAARIEHHRQGRPEHWRTVERWQHLDELIHADINPNEVVLL
ECVTTMVTNLLFDYGGDKDPDEWDYQAMEQAINAEIQSLIAACQRCPAKVVLVTNEVGVMLPTY

Specific function: ATP-dependent phosphorylation of adenosylcobinamide and adds GMP to adenosylcobinamide phosphate [H]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=139, Percent_Identity=99.2805755395683, Blast_Score=289, Evalue=5e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003203 [H]

Pfam domain/function: PF02283 CobU [H]

EC number: =2.7.1.156; =2.7.7.62 [H]

Molecular weight: Translated: 16216; Mature: 16216

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMILVTGGARSGKSRHAEALIGDSSQVLYIATSQILDDEMAARIEHHRQGRPEHWRTVER
CEEEEECCCCCCCCHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
WQHLDELIHADINPNEVVLLECVTTMVTNLLFDYGGDKDPDEWDYQAMEQAINAEIQSLI
HHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
AACQRCPAKVVLVTNEVGVMLPTY
HHHHHCCCEEEEEECCCCEEECCC
>Mature Secondary Structure
MMILVTGGARSGKSRHAEALIGDSSQVLYIATSQILDDEMAARIEHHRQGRPEHWRTVER
CEEEEECCCCCCCCHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
WQHLDELIHADINPNEVVLLECVTTMVTNLLFDYGGDKDPDEWDYQAMEQAINAEIQSLI
HHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
AACQRCPAKVVLVTNEVGVMLPTY
HHHHHCCCEEEEEECCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]