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The map label for this gene is nrdR

Identifier: 186477197

GI number: 186477197

Start: 2747791

End: 2748285

Strand: Reverse

Name: nrdR

Synonym: Bphy_2448

Alternate gene names: 186477197

Gene position: 2748285-2747791 (Counterclockwise)

Preceding gene: 186477198

Following gene: 186477196

Centisome position: 78.99

GC content: 66.26

Gene sequence:

>495_bases
ATGCGCTGCCCCTTCTGCCGGCACGACGACACGCAGGTCGTCGACTCGCGGGTGTCCGAAGACGGCGCCGCGATCCGGCG
CCGCCGGCGTTGCCCGGCCTGCGACAAGCGTTTTACGACGTACGAGCGGGTCGAGCTGGCGTTGCCTTCGGTCGTCAAGA
AGGACGGCAGCCGCACGGAATTCGATCGCCGCAAGATCGTTGCGAGCATGCAACTGGCACTGCGCAAGCGTCCAGTTGCG
GCCGACGCCATCGACGCTGCCGCGTCGCGCATCGAGTATCAGCTGCTTGGCAGCGGCGAGCGCGAAGTGCGCAGTGAGCG
CCTCGGCGAACTGGTGATGAACGAACTGCGCGCGCTCGACACAATCGCGTATGTGCGCTTTGCGTCCGTGTACCGGCGTT
TCGAAGACGTCTCCGAATTCGAGGACGTGATTGAGGAATTTCGCCGGACGAACGCACCGCCGGCCGCGCCCGCGAAGCCG
ACCCGCAAGCGCTGA

Upstream 100 bases:

>100_bases
CGACGTGCTGGACAACCCCGAAGACACGGCGACGATCGAGCGCGTGCGCGCGCAGGTCGCCGAGCTGACGCAGCGTTTCC
CGGTCTACCGCTAAGCCGCC

Downstream 100 bases:

>100_bases
TTGTTCGCGCATCCGCATTTTCTCTCCCTGAAGTTCTGCCGCGAATTCATTTGACGCACGTGCATTCTCGTGCGGGAATT
CGCGCGTCCGCCACCTGGCC

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 164; Mature: 164

Protein sequence:

>164_residues
MRCPFCRHDDTQVVDSRVSEDGAAIRRRRRCPACDKRFTTYERVELALPSVVKKDGSRTEFDRRKIVASMQLALRKRPVA
ADAIDAAASRIEYQLLGSGEREVRSERLGELVMNELRALDTIAYVRFASVYRRFEDVSEFEDVIEEFRRTNAPPAAPAKP
TRKR

Sequences:

>Translated_164_residues
MRCPFCRHDDTQVVDSRVSEDGAAIRRRRRCPACDKRFTTYERVELALPSVVKKDGSRTEFDRRKIVASMQLALRKRPVA
ADAIDAAASRIEYQLLGSGEREVRSERLGELVMNELRALDTIAYVRFASVYRRFEDVSEFEDVIEEFRRTNAPPAAPAKP
TRKR
>Mature_164_residues
MRCPFCRHDDTQVVDSRVSEDGAAIRRRRRCPACDKRFTTYERVELALPSVVKKDGSRTEFDRRKIVASMQLALRKRPVA
ADAIDAAASRIEYQLLGSGEREVRSERLGELVMNELRALDTIAYVRFASVYRRFEDVSEFEDVIEEFRRTNAPPAAPAKP
TRKR

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=144, Percent_Identity=50, Blast_Score=153, Evalue=7e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_BURP8 (B2JG93)

Other databases:

- EMBL:   CP001043
- RefSeq:   YP_001858667.1
- GeneID:   6243932
- GenomeReviews:   CP001043_GR
- KEGG:   bph:Bphy_2448
- HOGENOM:   HBG351755
- OMA:   FASVYRD
- ProtClustDB:   PRK00464
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 18879; Mature: 18879

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCPFCRHDDTQVVDSRVSEDGAAIRRRRRCPACDKRFTTYERVELALPSVVKKDGSRTE
CCCCCCCCCCHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCH
FDRRKIVASMQLALRKRPVAADAIDAAASRIEYQLLGSGEREVRSERLGELVMNELRALD
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
TIAYVRFASVYRRFEDVSEFEDVIEEFRRTNAPPAAPAKPTRKR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRCPFCRHDDTQVVDSRVSEDGAAIRRRRRCPACDKRFTTYERVELALPSVVKKDGSRTE
CCCCCCCCCCHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCH
FDRRKIVASMQLALRKRPVAADAIDAAASRIEYQLLGSGEREVRSERLGELVMNELRALD
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
TIAYVRFASVYRRFEDVSEFEDVIEEFRRTNAPPAAPAKPTRKR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA